Informing global polio eradication efforts through innovative modeling approaches

The Centers for Disease Control and Prevention, within the U.S. Department of Health and Human Services, forecasts a federal discretionary cooperative agreement titled "Informing global polio eradication efforts through innovative modeling approaches." The opportunity number is CDC-RFA-JG-27-0077, and the associated Assistance Listing is 93.185, Immunization Research, Demonstration, Public Information and Education Training and Clinical Skills Improvement Projects. The opportunity is categorized under Health and is intended to support work that informs global polio eradication efforts through disease modeling. The forecast identifies one expected award and estimated total program funding of $2,000,000. The planned cooperative agreement will provide critical disease modeling to support decision making related to polio eradication. The stated scope includes developing strategies for circulating vaccine-derived poliovirus type 2, or cVDPV2, outbreak response; determining optimal surveillance approaches following global wild poliovirus eradication; and developing surveillance approaches capable of detecting containment breaches. The work is also intended to assess the economic implications of outbreak response and surveillance strategies. These objectives place statistical and mathematical modeling at the center of the planned funded activity. In addition to the disease modeling objectives, the opportunity is intended to strengthen workforce capacity. The forecast states that the program will build capacity for a diverse public health workforce of statistical and mathematical modelers and will develop workforce capacity for students working in statistical and mathematical modeling for polio and other vaccine-preventable diseases. The source does not provide detailed allowable-cost rules, prohibited expenditures, indirect cost limitations, subaward restrictions, or other spending restrictions. It does state that cost sharing or matching is not required. Eligibility is broad. The forecast identifies Native American tribal organizations other than federally recognized tribal governments; nonprofits with 501(c)(3) status other than institutions of higher education; nonprofits without 501(c)(3) status other than institutions of higher education; private institutions of higher education; public and state controlled institutions of higher education; small businesses; independent school districts; county governments; special district governments; for-profit organizations other than small businesses; public housing authorities and Indian housing authorities; state governments; city or township governments; and federally recognized Native American tribal governments. The source also identifies Others and Unrestricted, subject to any clarification in the additional eligibility field. That field states N/A, so no additional eligibility restrictions are provided. This opportunity is currently a forecast rather than an open application. The forecast was issued and last updated on August 31, 2026. The estimated posting date is December 14, 2026, and the estimated application due date is February 12, 2027. Electronically submitted applications must be submitted no later than 11:59 p.m. Eastern Time on the listed application due date. Because only forecast information is provided, the source does not identify application forms, required narrative questions, attachments, a letter of intent, concept paper, pre-proposal, notice of intent, or other pre-application gating requirement. It also does not provide evaluation or scoring criteria. The estimated award date is August 1, 2027, and the estimated project start date is September 1, 2027. The opportunity is associated with fiscal year 2027, and the listed archive date is March 14, 2027. No project end date or complete period of performance is provided. The forecast does not state that the opportunity is annual, biennial, quarterly, continuously available, or otherwise recurring, so no recurrence is established from the available information. Questions regarding the forecast may be directed to Julie Jenks at JJenks@cdc.gov or 404-718-2794.

Align proposed modeling work with the stated priorities for cVDPV2 outbreak response, surveillance following global wild poliovirus eradication, detection of containment breaches, economic implications of outbreak response and surveillance strategies, and statistical and mathematical modeling workforce capacity.