Limited Competition: High Impact Specialized Innovation Programs in Clinical and Translational Science (RC2 Clinical Trial Optional)
This funding opportunity is designed to support innovative and high-risk projects that advance clinical and translational science at specific research hubs, encouraging the development of new capabilities and resources that can be shared with other institutions.
The purpose of the High Impact Specialized Innovation Programs (SIPs) funded through the RC2 mechanism is to support the development and demonstration of high risk/high reward unique projects, capabilities, research platforms, infrastructure and/or resources to significantly advance clinical and translational science at awarded UM1 Clinical and Translational Science Award (CTSA) Program hubs. Successful programs supported through this funding opportunity are expected to lay a strong foundation for future adoption and/or dissemination of capabilities to additional CTSA Program hubs.This is a Notice of Funding Opportunity (NOFO) for a Limited Competition that will invite application(s) from eligible organization(s) to apply. Please see Section III. Eligibility for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding.
Award Range
Not specified - Not specified
Total Program Funding
Not specified
Number of Awards
Not specified
Matching Requirement
No
Eligible Applicants
Additional Requirements
Eligibility is limited to primary UM1 CTSA awardee institutions or those applying under PAR-24-272. Partner organizations are not eligible as lead applicants. SIP awards must be linked to an active UM1 award and are limited to two per hub.
Geographic Eligibility
All
Application Opens
March 9, 2026
Application Closes
September 28, 2026
Grantor
U.S. Department of Health and Human Services (National Institutes of Health)
Phone
301-827-2017Subscribe to view contact details

