Animal and Biological Material Resource Centers (P40) (Clinical Trials Not-Allowed)

The National Institutes of Health (NIH), a part of the U.S. Department of Health and Human Services, has issued a Funding Opportunity Announcement (FOA) under the identifier RFA-OD-23-001. This FOA, titled "Animal and Biological Material Resource Centers (P40) (Clinical Trials Not-Allowed)," seeks to fund grant applications aimed at supporting the biomedical research infrastructure through the development and maintenance of resource centers. These centers are designed to support special colonies of laboratory animals and provide critical resources such as informatics tools, reagents, and cultures, which are essential to facilitating rigorous, reproducible biomedical research across a broad range of disciplines. The purpose of this FOA is to enable the establishment or continued operation of Animal and Biological Material Resource Centers that have broad relevance to multiple NIH Institutes and Centers. These centers are expected to align with the NIH Office of Research Infrastructure Programs (ORIP), which supports NIH-wide infrastructure needs. Resources provided by the centers must enhance experimental reproducibility and scientific rigor. Applications may propose either to maintain existing, proven resources or to develop new resources where necessary. Applicants are encouraged to consult with NIH staff early in the process to determine the alignment of their resource proposal with ORIP's priorities and the competitiveness of their application. Funding will be provided through grants, and the opportunity is classified under the "Health" category of funding activity. No cost sharing or matching is required. There are no explicit award floor or ceiling amounts provided in the FOA. Instead, the size of the awards will depend on the scope and need demonstrated in each application. The FOA is intended to support projects with national relevance, and foreign institutions are not eligible to apply, although foreign components of U.S.-based organizations are allowed. Eligibility for this grant is broad and includes state and local governments, higher education institutions, tribal entities, non-profit and for-profit organizations, as well as special interest groups such as minority-serving institutions and faith-based organizations. This inclusive approach ensures that a wide range of qualified entities can contribute to advancing biomedical research infrastructure. However, non-U.S. institutions are excluded from applying directly, which maintains the national scope of the initiative. The application process does not involve pre-application steps such as a Letter of Intent. Applications for the current cycle are being accepted through May 9, 2026. The FOA was originally posted on January 9, 2023, and last updated on January 20, 2026. The next anticipated application cycle, inferred from the current due date and the recurring nature of the opportunity, is projected for May 2027. The FOA is available on the NIH Grants website, and applicants encountering issues can contact NIH Grants Information via email at grantsinfo@nih.gov. This funding opportunity is ideal for institutions engaged in biomedical research and development, particularly those looking to enhance national research capabilities through the development and dissemination of animal models and biological resources. Projects funded under this FOA will play a vital role in strengthening the nation’s research infrastructure and supporting the scientific community at large.

Applicants should clearly demonstrate national relevance across NIH ICs and reproducibility impact. Consult NIH staff before applying.