Logistics Center for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) (U24 Clinical Trials Not Allowed)

The National Institutes of Health (NIH), through the Office of Strategic Coordination within the Common Fund, has released a funding opportunity titled Logistics Center for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI). This initiative is part of a broader NIH effort to accelerate biomedical discovery and translate research into improved prevention strategies and treatments. The PRIMED-AI program focuses on advancing clinical decision support tools that integrate imaging data with other multimodal health data sources, enabling more personalized and effective healthcare solutions. The purpose of this specific funding opportunity is to establish a centralized Logistics Center that will coordinate and support the activities of the PRIMED-AI Consortium. The center will play a critical role in maximizing program impact by providing administrative, evaluation, and outreach infrastructure. It will facilitate collaboration among consortium members, manage communication and meetings, and oversee dissemination of tools and resources developed through the program. The Logistics Center is also responsible for creating and maintaining a web portal to promote access to PRIMED-AI outputs and support engagement with scientific, clinical, and patient communities. Funding for this opportunity is provided through a cooperative agreement mechanism, indicating substantial involvement from NIH program staff throughout the project lifecycle. The total anticipated funding is approximately 750000 dollars, with one award expected. The project period may extend up to five years, with a first-year budget cap of 575000 dollars in direct costs and up to 2500000 dollars annually for the remaining years. A significant portion of the budget in later years must be allocated to restricted funds supporting collaboration and outreach initiatives, including partnerships and development of educational materials to improve adoption of AI-based tools. Eligible applicants include a wide range of U.S.-based entities such as higher education institutions, nonprofits, for-profit organizations, and government entities at the state, local, and tribal levels. Foreign organizations and non-U.S. components are not eligible. Applications must be submitted by organizations with appropriate registrations, including SAM, Grants.gov, and eRA Commons. A multi-Principal Investigator structure is required, reflecting the complexity and collaborative nature of the Logistics Center. The application process requires strict adherence to NIH submission guidelines and includes detailed components such as a research strategy, administration plan, evaluation framework, outreach strategy, and a comprehensive milestones and timeline document. Applications must be submitted electronically via Grants.gov or NIH systems by October 2, 2026. Review will occur through NIH peer review processes, evaluating criteria such as significance, investigator qualifications, innovation, approach, and environment. Awards are expected to begin in July 2027 following advisory council review. There is no cost-sharing requirement for this opportunity. Applicants must also comply with NIH policies on data management, cybersecurity, and reporting. The Logistics Center will be expected to collaborate closely with other PRIMED-AI components, participate in consortium governance, and contribute to shared policies and standards. For inquiries, applicants may contact the PRIMED-AI program via email at ODPRIMED-AI@od.nih.gov. This funding opportunity represents a significant investment in advancing AI-driven precision medicine through coordinated infrastructure and collaboration.

Emphasize demonstrated experience managing large scale collaborative research programs and clearly define coordination strategies milestones and evaluation mechanisms aligned with PRIMED-AI goals