Ending HIV and TB as public health threats through an accelerated and sustained comprehensive response in India

The U.S. Department of Health and Human Services, through the Centers for Disease Control and Prevention, Global Health Center, Division of Global HIV and Tuberculosis, is offering the cooperative agreement Ending HIV and TB as public health threats through an accelerated and sustained comprehensive response in India under opportunity CDC-RFA-JG-26-0142. The program supports U.S. global health priorities by reducing HIV, tuberculosis, and other priority disease incidence and mortality through data-driven activities and stronger public health systems. CDC intends the award to support India's Ministry of Health and Family Welfare, including the National AIDS Control Organization, Central Tuberculosis Division, State AIDS Control Societies, and other national programs. The program emphasizes efficiency, sustainability, local ownership, evidence-based practices, and strengthened capacity to prevent, detect, and respond to infectious disease threats. The purpose is to accelerate progress toward ending HIV and TB as public health threats while building sustainable health systems that improve efficiency, country program ownership, and global health security. Proposed activities should strengthen evidence-based HIV and TB programs, implement integrated models of service delivery for HIV, TB, and associated comorbidities, and strengthen country-led ownership through resilient systems. Priority work includes prevention of new infections, innovative case finding, early diagnosis and linkage to care, treatment adherence and continuity, viral load suppression, TB prevention and molecular diagnosis, management of drug resistance, integration of hepatitis, STI, noncommunicable disease, and other relevant services, workforce development, surveillance, data use, and cooperation with government, community, faith-based, private-sector, and other interest holders. Projects must be conducted in India. CDC expects total Year 1 funding of 6000000 dollars across approximately one to two awards and encourages applicants to apply for the expected total NOFO funding for Year 1. A request exceeding 6000000 dollars for Year 1 is nonresponsive. The planned period of performance consists of five 12-month budget periods, for a total of five years, with continuation funding dependent on available funds, satisfactory progress, program priorities, and the federal government's determination that continued funding is in its best interest. Applicants must organize Year 1 activities into anticipated funding components covering quarterly global HIV and TB planning targets and activities, additional targets and activities, global TB priorities, and emerging public health priorities. CDC may use results-based funding linked to measurable milestones and program indicators. There is no required cost sharing or matching. Funds must be used for reasonable program purposes consistent with the award and applicable law. Restrictions include clinical research, generally pre-award costs without prior written approval, prohibited lobbying activities, needle exchange programs, and specified abortion and involuntary sterilization activities. Furniture and equipment generally may not be purchased unless clearly identified and justified. Eligibility is unrestricted by organizational type. Eligible applicants include state, county, city or township, and special district governments; independent school districts; public and state-controlled and private institutions of higher education; federally recognized Native American tribal governments and other Native American tribal organizations; public and Indian housing authorities; nonprofits with or without 501(c)(3) status; for-profit organizations other than small businesses; small businesses; and foreign or non-U.S.-based public or private nonprofit or for-profit entities. Regardless of organizational type, the project must be conducted in India. A local organization applying under the NOFO must comply with India's Foreign Contribution Regulation Act and submit documentation of active FCRA registration; failure to provide required FCRA documentation makes the application nonresponsive. CDC also provides a local organization funding preference worth 30 additional points during selection when sufficient documentation establishes that the applicant meets the applicable global HIV and TB local organization definition. Applications are submitted through Grants.gov for opportunity CDC-RFA-JG-26-0142. Applicants must maintain required SAM.gov and Grants.gov registrations and submit by 11:59 p.m. Eastern Time on September 16, 2026. The application includes a one-page project abstract, a project narrative limited to 20 pages, a budget narrative, required attachments, SF-424, SF-424A, and SF-LLL when applicable. The project narrative must address Background; Approach, including Strategies and Activities and Outcomes; Organizational Capacity; Coordination; Evaluation and Performance Measurement Plan; Data Management Plan; and Work Plan. Required attachments include a table of contents, experience statement, financial capability statement, resumes and job descriptions, organizational chart, statement of prior award, and required FCRA registration for applicable local organizations. Additional conditional attachments include an indirect cost agreement, letters of commitment, report on overlap, and local organization preference documentation. Application materials must be in English, monetary amounts must be stated in U.S. dollars, and required narrative formatting includes 12-point font, single spacing, one-inch margins, and page numbers. Applications first undergo a responsiveness review. Applications that are late, exceed the project narrative page limit, request more than the Year 1 funding limit, propose research, fail eligibility requirements, are not in English, use a currency other than U.S. dollars in the budget or budget narrative, fail required FCRA documentation where applicable, or fall outside the NOFO scope will not advance. Responsive applications undergo merit review for a total of 100 points: Approach is worth 40 points, Organizational Capacity is worth 35 points, and Data, Monitoring, and Evaluation is worth 25 points. The Approach review emphasizes innovative and sustainable HIV and TB services, effective case finding and linkage to care, treatment and re-engagement strategies supporting durable viral suppression, and capacity to work with national public health institutes to strengthen surveillance and response. Applicants qualifying for the local organization preference receive 30 additional points during the selection process. CDC expects to inform applicants of their application status by the end of December 2026, with an expected award and project start date of January 1, 2027. The NOFO does not state that this competition recurs annually or on another regular schedule, so no recurrence is assumed. Program questions may be directed to DGHTNOFOs@cdc.gov. The named grants management contact is Randolph Williams at gur2@cdc.gov. Grants.gov technical support is available at support@grants.gov and 1-800-518-4726 in the United States, with international telephone support at 1-606-545-5035. Award recipients must complete required monitoring, evaluation, data management, performance, and financial reporting, including a detailed Evaluation and Performance Measurement Plan and Data Management Plan within the first six months of the award.

Follow the exact required project narrative headings and order and keep the narrative within 20 pages. Do not request more than 6000000 dollars for Year 1. Present feasible, innovative, sustainable approaches for HIV and TB case finding, linkage, treatment continuity, re-engagement, viral suppression, and integrated care. Demonstrate transition to local ownership and effective cooperation with national public health institutions. Support claims of organizational capacity with the required attachments and recent relevant experience. Link budget amounts to activities and key milestones, organize Year 1 costs by funding component, and address monitoring, evaluation, data management, and measurable outcomes. Local organizations should ensure active FCRA documentation is included, and qualifying local organizations should provide sufficient documentation for the 30-point local organization funding preference.