Strategic Prevention Framework - Partnerships for Success for Communities/Tribes

The Strategic Prevention Framework - Partnerships for Success for Communities/Tribes program is administered by the U.S. Department of Health and Human Services through the Substance Abuse and Mental Health Services Administration (SAMHSA), specifically under the Center for Substance Abuse Prevention. This federal initiative is part of a broader national effort to address substance use and its related behavioral health challenges by investing in prevention infrastructure and community-based strategies. The program aligns with SAMHSA’s mission to reduce the impact of substance abuse and mental illness on America’s communities by supporting evidence-based prevention services and strengthening local capacity. The primary purpose of this funding opportunity is to prevent and reduce the initiation and progression of substance use and its associated consequences. The program emphasizes strengthening protective factors, reducing risk factors, building resilience, and promoting overall well-being. It is designed to support communities and tribal entities in implementing comprehensive prevention strategies that are evidence-based, evidence-informed, or community-defined. In addition to direct service delivery, the program seeks to expand and enhance the capacity of prevention providers to effectively implement and sustain these strategies. Funding under this opportunity is intended to support community-based prevention services, including planning, implementation, evaluation, and capacity-building activities. While specific allowable costs are not detailed in the forecast, typical SAMHSA prevention grants support personnel, program implementation, training, evaluation, and infrastructure development necessary to deliver prevention services. There is no cost-sharing or matching requirement associated with this opportunity, which lowers the barrier to entry for eligible organizations and allows full federal funding to be utilized for program activities. Eligibility for this program is broad and inclusive, targeting entities capable of delivering prevention services within communities and tribal settings. Eligible applicants include political subdivisions of states, Indian tribes and tribal organizations, health facilities or programs operated by or in coordination with the Indian Health Service, and other public or private nonprofit organizations, including faith-based organizations. This inclusive eligibility structure ensures that a wide range of organizations with community reach and prevention expertise can participate. The application process is expected to be administered through Grants.gov once the opportunity is officially posted. As this is currently a forecasted opportunity, specific submission requirements, application components, and evaluation criteria have not yet been released. However, SAMHSA grants typically require detailed project narratives, budgets, work plans, and evaluation strategies. Applicants are generally evaluated based on the quality of their proposed approach, organizational capacity, and alignment with program goals. The timeline for this opportunity indicates that it is in the forecast stage, with an estimated posting date of May 29, 2026. Application deadlines, award dates, and project start dates have not yet been specified. The program is expected to make approximately 32 awards, with total program funding estimated at $8,200,000. Interested applicants are encouraged to monitor Grants.gov for updates and prepare in advance by aligning their prevention strategies with SAMHSA priorities. For additional information, applicants may contact the program representative via email or phone as provided in the opportunity listing.