Grants for Public Housing Authorities

This grant provides funding for innovative researchers to explore groundbreaking ideas that could transform the prevention and treatment of HIV/AIDS, particularly among individuals with substance use disorders.

This grant provides funding to U.S. higher education institutions to support predoctoral training programs in neuroscience, focusing on developing a diverse group of skilled scientists through comprehensive research training and mentorship.

This funding opportunity supports researchers with a strong background in promoting diversity, equity, inclusion, and accessibility in biomedical fields, enabling them to conduct scientific research while advancing DEIA initiatives within the academic and scientific communities.

Reissue of RFA-NS-18-019: Understanding the dynamic activity of neural circuits is central to the NIH BRAIN Initiative. The invention, proof-of-concept investigation, and optimization of new technologies through iterative feedback from end users are key components of the BRAIN Initiative. This FOA seeks applications to optimize existing or emerging technologies through iterative testing with end users. The technologies and approaches should have potential to address major challenges associated with recording and modulation (including various modalities for stimulation/activation, inhibition and manipulation) of cells (i.e., neuronal and non-neuronal) and networks to enable transformative understanding of dynamic signaling in the central nervous system (CNS). These technologies and approaches should have previously demonstrated their transformative potential through initial proof-of-concept testing and are now ready for accelerated refinement. In conjunction, the manufacturing techniques should be scalable towards sustainable, broad dissemination and user-friendly incorporation into regular neuroscience research.Proposed technologies should be compatible with experiments in behaving animals, validated under in vivo experimental conditions, and capable of reducing major barriers to conducting neurobiological experiments and making new discoveries about the CNS. Technologies may engage diverse types of signaling beyond neuronal electrical activity such as optical, electrical, magnetic, acoustic or genetic recording/manipulation. Applications that seek to integrate multiple approaches are encouraged. If suitable, applications are expected to integrate appropriate domains of expertise, including biological, chemical and physical sciences, engineering, computational modeling and statistical analysis.

Funding Opportunity Description The NIH Research Education Program (R25) supports research educational activities that complement other formal training programs in the mission areas of the NIH Institutes and Centers. The overarching goal of this R25 program is to support educational activities that encourage individuals from diverse backgrounds, including those from groups underrepresented in the biomedical and behavioral sciences, to pursue further studies or careers in research. Background A major goal of the National Plan to address Alzheimer’s Disease (AD) and Alzheimer’s Disease-related Dementias (ADRD) is to reduce the burden of AD/ADRD by accelerating research toward treatments, improving care and support for people facing these conditions now, and reducing the risk of AD/ADRD by promoting brain health. Despite this, there is a shortage of scientists conducting the wide variety of necessary innovative and interdisciplinary research projects, including basic biomedical, clinical, translational, prevention, and treatment research on AD/ADRD. This Funding Opportunity Announcement (FOA) aims to address goal G-4 of the National Institute on Aging's Strategic Directions for Research (2020-2025): Attract and train more researchers from diverse scientific and cultural backgrounds." This will include supporting the recruitment of early-stage investigators from diverse backgrounds, including those from groups underrepresented in the biomedical and behavioral sciences, to the NIH AD/ADRD portfolio. This FOA also aims to address the lack of early exposure to high-quality, hands-on research education experiences in the AD/ADRD field, another major barrier to increasing the AD/ADRD capable workforce. To further expand the AD/ADRD training pipeline for earlier stage students, NIA will support summer research experiences for high school students, undergraduates, or science teachers. The expectation is that such a program would incubate and develop the next generation of early-stage investigators to pursue research careers representative of in NIA mission critical areas, namely AD/ADRD research. Proposed programs should provide authentic "open-ended", hands-on exposure to AD/ADRD research as it relates to aging as part of a comprehensive program based in sound educational practices designed to stimulate the interest and advance the knowledge base of participants. In addition to hands-on research experiences, programs are expected to include complementary educational enrichment activities that support the participants' scientific development, such as relevant workshops (e.g., scientific writing and presentation skills), journal clubs, technical laboratory coursework, and training in rigor and reproducibility. Program goals and objectives should be grounded in literature and appropriate for the educational level of the audience to be reached, including the content to be conveyed, and the intended outcome(s). Outcomes for high school students may include preparing them for undergraduate admissions and enhancing their interest in pursuing a science decree. Outcomes for college students may include: reinforcing their intent to graduate with a science degree, preparing them for graduate or medical school admissions, and/or preparing them for careers in AD/ADRD research. Support for science teachers will be limited to those programs with a clear plan for how teachers will utilize their summer experience in their teaching during the school year, such as enhancing the STEM curriculum or increasing number of STEM courses taught. Focus on High School Students, Undergraduates, or Science Teachers: Science education research has demonstrated that early exposure to scientific research leads to the retention of trainees in science, technology, engineering, and mathematics (STEM). The President’s Council of Advisors on Science and Technology (PCAST) specifically highlights the need for retention of trainees in STEM by involving them in contemporary, hands-on research experiences especially during the first two years of college. Summer research experiences provide important experiential learning to sustain students interests in STEM and medicine careers. The short-term summer experience, in contrast to a year-long experience, allows for a focused and concentrated effort on instruction, and intentionally coincides with the time of year when the target populations of this program (i.e., high school students, undergraduate college students, and science teachers) would typically have the opportunity to engage in such a research educational experience. For the purpose of this announcement, institutions should explain how this program will be developed in a way that will foster diversity and inclusion at their organization. As indicated below, applicants must include a Recruitment Plan to Enhance Diversity which describes the program’s proposed recruitment efforts and how the proposed plan reflects past experiences in recruiting individuals from diverse backgrounds, including those from groups underrepresented in the biomedical and behavioral sciences (see NOT-OD-20-031 for additional information on NIH's Notice of Interest in Diversity). All programs are expected to be inclusive, supportive, and safe, and to provide opportunities for participants to interact with investigators who could contribute to their growth. Applications from a variety of institutions, including those from minority serving institutions (MSIs), are encouraged. Applicants should consider how the developed programs can optimize participation and potentially include additional participants from outside the applicant institution, especially those in local and/or affiliated institutions. Applicants must demonstrate how this program will add significant value over existing programs at the applicant institution. Each institution must have a unique program structure that maximizes resources, departments, and faculty at the applicant institution to address the target population. Applicants are encouraged to propose collaborations with affiliated and/or local institutions, as appropriate. Applicants are also encouraged to partner with existing NIH-funded or other federally-funded resources and programs and leverage training activities from both federal and private-sector partners including, but not limited to, the following: Alzheimer's Disease Research Centers (ADRCs) Centers on the Demography and Economics of Aging Claude D. Pepper Older Americans Independence Center (OAIC) Edward R. Roybal Centers for Translation Research in the Behavioral and Social Sciences of Aging Nathan Shock Centers Resource Centers for Minority Aging Research (RCMAR) NCATS Clinical and Translational Science Awards (CTSA) Research Centers in Minority Institutions Program (RCMI) Non-Responsiveness Criteria Applications that propose programs primarily outside of AD/ADRD research, or have a general STEM focus, will be considered non-responsive to this FOA and will be withdrawn prior to review. Research education programs may complement ongoing research training and education occurring at the applicant institution, but the proposed educational experiences must be distinct from those training and education programs currently receiving Federal support. R25 programs may augment institutional research training programs (e.g., T32, T90), but cannot be used to replace or circumvent Ruth L. Kirschstein National Research Service Award (NRSA) programs,

This funding opportunity supports researchers who have received a specific career development award to conduct small-scale projects that will help them become independent investigators.

Funding Opportunity Description The NIH Research Education Program (R25) supports research educational activities that complement other formal training programs in the mission areas of the NIH Institutes and Centers. The overarching goal of this R25 program is to support educational activities that encourage individuals from diverse backgrounds, including those from groups underrepresented in the biomedical and behavioral sciences, to pursue further studies or careers in research. Background A major goal of the National Plan to address Alzheimer’s Disease (AD) and Alzheimer’s Disease-related Dementias (ADRD) is to reduce the burden of AD/ADRD by accelerating research toward treatments, improving care and support for people facing these conditions now, and reducing the risk of AD/ADRD by promoting brain health. Despite this, there is a shortage of scientists conducting the wide variety of necessary innovative and interdisciplinary research projects, including basic biomedical, clinical, translational, prevention, and treatment research on AD/ADRD. This Funding Opportunity Annoucnment (FOA) aims to address goal G-4 of the National Institute on Aging's Strategic Directions for Research (2020-2025): "Attract and train more researchers from diverse scientific and cultural backgrounds." This will include supporting the recruitment of a variety of early-stage investigators from diverse backgrounds, including those from groups underrepresented in the biomedical and behavioral sciences, to the NIH AD/ADRD portfolio. This FOA also aims to address the lack of early exposure to high-quality, hands-on research education experiences in the AD/ADRD field, another major barrier to increasing the AD/ADRD capable workforce. To further expand the AD/ADRD training pipeline, NIA will support one-to-two-year intensive research experiences for recent baccalaureates, with a focus on receipt of mentorship for pursuing future research careers. The expectation is that such a program would help to transition the next generation of early-stage investigators into research careers representative of NIA mission critical areas, namely AD/ADRD research. Proposed programs should involve participants in independent research projects in AD/ADRD as it relates to aging. Participants will be required to work as research postbaccalaureates at nine person-months (75% full-time) effort, with the other three person-months (25% full-time effort) devoted to further academic and professional development. Academic development opportunities may include courses, seminars, or supplemental instruction that will enhance the technical, operational, and professional skills of the participants. Training in rigor and reproducibility is required. Professional development opportunities may include entrance exam preparation and conference and workshop participation. Program training objectives and mentoring activities should be grounded in literature and enable trainees to pursue advanced degrees and other research-related science career opportunities. Focus on Postbaccalaureates: Postbaccalaureate programs consist of studies pursued after the completion of one's bachelor’s degree, but before entering an advanced degree program, such as a master s, doctoral, or clinical degree program. The Association of American Medical Colleges (AAMC) reports an increased number of prospective medical students taking time off between the completion of their undergraduate education and enrollment in medical school. While students may take these gap years for a variety of reasons and be involved in a range of activities, almost half of such students report being involved in research during this time. Moreover, the COVID-19 pandemic has impacted students decisions to take gap years in a way that has been leading to a rise in the number of students taking this path. Literature shows that postbaccalaureate programs enable recent graduates to pursue advanced degrees and other research-related science career opportunities. For the purpose of this announcement, institutions should explain how this program will be developed in a way that will foster diversity and inclusion at their organization. As indicated below, applicants must include a Recruitment Plan to Enhance Diversity which describes the program’s proposed recruitment efforts and how the proposed plan reflects past experiences in recruiting individuals from diverse backgrounds, including those from groups underrepresented in the biomedical and behavioral sciences (see NOT-OD-20-031 for additional information on NIH's Notice of Interest in Diversity). All programs are expected to be inclusive, supportive, and safe, and to provide opportunities for participants to interact with investigators who could contribute to their growth. Applications from a variety of institutions, including those from minority serving institutions (MSIs), are encouraged. Applicants should consider how the developed programs can optimize participation and potentially include additional participants from outside the applicant institution, especially those in local and/or affiliated institutions. Applicants must demonstrate how this program will add significant value over existing programs at the applicant institution. Each institution must have a unique program structure that maximizes resources, departments, and faculty at the applicant institution. Applicants are encouraged to propose collaborations with affiliated and/or local institutions, as appropriate. Applicants are also encouraged to partner with existing NIH-funded or other federally funded resources and programs and leverage training activities from both federal and private-sector partners including, but not limited to, the following: Alzheimer's Disease Research Centers (ARDCs) Centers on the Demography and Economics of Aging Claude D. Pepper Older Americans Independence Center (OAIC) Edward R. Roybal Centers for Translation Research in the Behavioral and Social Sciences of Aging Nathan Shock Centers Resource Centers for Minority Aging Research (RCMAR) NCATS Clinical and Translational Science Awards (CTSA) Research Centers in Minority Institutions Program (RCMI) Non-Responsiveness Criteria Applications that propose programs primarily outside of AD/ADRD research, or have a general STEM focus, will be considered non-responsive to this FOA and will be withdrawn prior to review. Research education programs may complement ongoing research training and education occurring at the applicant institution, but the proposed educational experiences must be distinct from those training and education programs currently receiving Federal support. R25 programs may augment institutional research training programs (e.g., T32, T90), but cannot be used to replace or circumvent Ruth L. Kirschstein National Research Service Award (NRSA) programs.

This funding opportunity supports early-stage researchers in the U.S. who are developing innovative projects to address the intersection of substance use disorders and HIV, with the goal of improving treatment and reducing incidence in affected populations.

This funding opportunity provides substantial financial support to higher education institutions and nonprofit organizations to establish collaborative centers that advance research and resources for HIV/AIDS.

This funding opportunity provides significant financial support to U.S. higher education institutions and research organizations with established HIV/AIDS research programs, enabling them to enhance their research infrastructure and foster interdisciplinary collaboration in the fight against HIV/AIDS.

The purpose of this Funding Opportunity Announcement (FOA) is to invite R21 applications on chronic conditions understudied among women and/or that disproportionately affect populations of women who are understudied, underrepresented, and underreported in biomedical Research should align with Goal 1 of the 2019-2023 Trans-NIH Strategic Plan for Women's Health Research "Advancing Science for the Health of Women." The awards under this FOA will be administered by NIH ICs using funds that have been made available through the Office of Research on Womens Health (ORWH) and the scientific partnering Institutes and Centers across NIH.

The purpose of this Funding Opportunity Announcement (FOA) is to invite R01 applications on chronic conditions understudied among women and/or that disproportionately affect populations of women who are understudied, underrepresented, and underreported in biomedical Research should align with Goal 1 of the 2019-2023 Trans-NIH Strategic Plan for Women's Health Research "Advancing Science for the Health of Women." The awards under this FOA will be administered by NIH ICs using funds that have been made available through the Office of Research on Womens Health (ORWH) and the scientific partnering Institutes and Centers across NIH.

This initiative will support national service centers for molecular structure determination by high resolution cryoelectron microscopy (cryoEM). The centers will provide access to state-of-the-art equipment, technical support, and training for the production and analysis of high-resolution data and offer equal-opportunity nationwide access to services through an open application process.

This funding opportunity provides financial support to U.S.-based organizations for the late-stage development and dissemination of biomedical technologies that have shown laboratory feasibility, aiming to enhance their accessibility and usability in the research community.

This funding opportunity supports the creation of mentoring networks that provide professional development and career guidance for graduate students, postdoctoral scholars, and early-career researchers in mental health, helping them advance towards independent research careers.

This funding opportunity supports U.S. institutions in developing educational programs for psychiatry residents to enhance their research skills and encourage careers in mental health research.

This funding opportunity supports short courses that train researchers in advanced mental health research skills, targeting graduate students, postdoctoral scholars, and early-career investigators across the nation.

This funding opportunity supports innovative research projects aimed at improving drug safety and effectiveness for pregnant and lactating individuals, children, and those with disabilities, encouraging collaboration among various institutions and disciplines.

This funding opportunity supports research aimed at improving drug safety and effectiveness for pregnant women, breastfeeding mothers, and children, encouraging innovative studies that address their unique health needs.

This funding opportunity supports the development and sharing of valuable genomic resources for researchers and organizations involved in basic and clinical genomics, ensuring broad access and community engagement.