Grants for Public Housing Authorities

This funding provides financial and technical support to organizations and partners working to remove barriers in waterways, helping to restore fish passage and improve aquatic ecosystems across the United States.

This funding opportunity supports researchers in developing and testing innovative devices for diagnosing and treating disorders of the nervous system through small clinical studies and safety assessments.

The National Institute on Drug Abuse (NIDA) Cutting-Edge Basic Research Award (CEBRA) is designed to foster highly innovative or conceptually creative research related to the etiology, pathophysiology, prevention, or treatment of substance use disorders (SUDs). It supports high-risk and potentially high-impact research that is underrepresented or not included in NIDA's current portfolio that has the potential to transform SUD research. The proposed research should: 1. develop, and/or adapt, revolutionary techniques or methods for addiction research or that show promising future applicability to SUD research; and /or 2. test an innovative and significant hypothesis for which there are scant precedent or preliminary data and which, if confirmed, would transform current thinking.

This Notice of Funding Opportunity (NOFO) invites applications to participate in a research program cooperative agreement to support theOptimizing Health of Children and Adolescents with Perinatal HIV Exposure Initiative. The objective of this NOFO is to generate information needed to develop and to test interventions for the early detection and reduction of long-term effects of in utero/perinatal exposure toantiretroviral therapy (ART) and/or HIV among individuals who are HIV exposed but uninfected (IHEU).Investigators with innovative thinking and new approaches to address the public health issues facing IHEUs are encouraged to apply.

Program Description Overview The U.S. Department of Justice (DOJ), Office of Justice Programs (OJP), Office for Victims of Crime (OVC) is seeking applications for funding. OJP is committed to advancing work that promotes civil rights and equity, increases access to justice, supports crime victims and individuals impacted by the justice system, strengthens community safety and protects the public from crime and evolving threats, and builds trust between law enforcement and the community. With this solicitation, OVC seeks to provide funding for housing services for victims of human trafficking, as defined by 22 U.S.C. § 7102(11). This program furthers the DOJ’s mission to uphold the rule of law, to keep our country safe, and to protect civil rights.

This funding opportunity supports innovative projects that develop new technologies for recording and modulating brain activity, aimed at advancing research on central nervous system diseases and disorders.

This funding opportunity provides financial support for institutions to create and manage accessible data archives that enhance neuroscience research by storing and sharing data generated by the BRAIN Initiative and related studies, while promoting inclusivity in research participation.

This funding opportunity supports innovative pilot research projects that explore the biological, behavioral, and social factors influencing HIV-related health issues, particularly those affecting kidney and digestive diseases.

State Promotion of Strategies to Advance Oral Health is a three-year competitive announcement that continues the Centers for Disease Control and Prevention's investment in supporting oral health programs. This Funding Opportunity Announcement aims to enable recipients to focus on priority populations and the following strategies: 1) access to optimally fluoridated water and receipt of Evidence-based Preventive Dental Services, 2) adherence to infection prevention and control recommendations, 3) access to data to build evidence for public health practice, and 4) access to care and untreated decay, and 5) foundational information supporting integrated medical and dental services for persons with diabetes. The proposed program follows previous Notice of Funding Opportunities (NOFOs) and incorporates programmatic strategies implemented in NOFO DP18-1810 [FY2018 FY2023].

Every year more than 795,000 people in the United States have a stroke. On average, thats 1 person every 40 seconds. On average, 1 American dies from a stroke every 3 minutes and 14 seconds. Approximately 9.4 million American adults 20 years of age self-report having had a stroke. These data are disturbing, more so as 80% of strokes are preventable.Prevention begins with implementing equity-focused systems and interventions that assist populations at the highest risk in detecting and managing cardiovascular disease (CVD) and mitigating systemic social conditions that contribute to the increased prevalence of CVD. Roughly 1 in 10 (9.9% 28.6 million) adults in the US have at least 1 type of CVD, including coronary heart disease, heart failure, or stroke. This number excludes hypertension, a risk factor for and cause of CVD but not a type of CVD. However, hypertension or high blood pressure is a critical risk factor for stroke. An estimated 120 million American adults (48.1%) have it, most (3 in 4) dont have it controlled, and 1 in 5 adults is unaware they have hypertension. High blood cholesterol, smoking, obesity, and diabetes also contribute to stroke risk.Heart disease, stroke, and their modifiable risk factors are experienced disproportionately throughout the US population based on race and ethnicity, social factors, and geography. Non-Hispanic Black Americans have a higher prevalence and highest death rate from stroke than any other racial group. While non-Hispanic Blacks had the highest age-adjusted stroke death among all races and ethnicities (59.6 per 100,000) in 2021, the age-adjusted stroke death rate for individuals across the board increased from 38.8 per 100,000 in 2020 to 41.1 per 100,000 in 2021. Stroke deaths also increased in southern states, where populations at a higher risk, specifically communities of color, exist. These numbers highlight the critical need to improve access to quality care for those at the highest risk of stroke and for stroke patients.In 2001, Congress provided funding to CDC to establish the Paul Coverdell National Acute Stroke Registry, named after the late US Senator Paul Coverdell of Georgia, who suffered a fatal stroke in 2000 while serving in Congress. In 2012, as the program expanded, the name changed to the Paul Coverdell National Acute Stroke Program. The aim has been to support the implementation of comprehensive stroke systems for individuals at the highest risk of stroke and for stroke patients across the continuum of care from the onset of stroke symptoms through rehabilitation and recovery.This new iteration of Coverdell supports state stroke systems in partnerships with learning collaboratives or coalitions to improve state-level stroke care for those at the highest risk. Recipients will be required to execute a dual approach to addressing stroke in the coordinated systems of care and the implementation of prevention activities in community settings. Recipients will continue their collection and analysis of in-hospital stroke data for those who have experienced a stroke while adding a deep focus on understanding and mitigating the stroke risks among individuals in their communities, also ensuring post-discharge follow-up in either rehabilitation facilities or other community-supportive recovery services.This NOFO requires Coverdell recipients to integrate their work with CDCs other funded programs in states where they exist to mitigate systemic inequities and reduce the prevalence of CVD and hypertension so that another person doesnt die from a stroke every 3 minutes and 14 seconds.

With this solicitation, BJA seeks to support law enforcement, correctional officers, probation and parole, and sheriffs departments in effectively partnering with mental health, substance use, community service professionals and agencies to promote public safety and make sure that appropriate responses are provided to individuals in crisis who have behavioral health conditions, intellectual disabilities, developmental disabilities, or physical disabilities, and/or traumatic brain injuries. Funding Categories: Category 1: Training Program for Law Enforcement Officers, including campus-based police; law enforcement agencies, including probation and parole (field-based); and sheriff's departments (patrol-based) Category 2: Training Program for Correctional Officers, Probation and Parole (facility-based), and Sheriff Departments (facility-based)

The NIH Directors New Innovator Award Program supports early stage investigators of exceptional creativity who propose bold and highly innovative research projects with the potential to produce a major impact on broad, important areas relevant to the mission of NIH. For the program to support the best possible researchers and research, applications are sought which reflect the full diversity of the research workforce. To support innovative and novel research across the vast NIH mission, individuals from diverse backgrounds (including those from underrepresented groups; see Notice of NIHs Interest in Diversity) and from the full spectrum of eligible institutions in all geographic locations are encouraged to apply to this Notice of Funding Opportunity. Applications in all topics relevant to the broad mission of NIH are welcome, including, but not limited to, behavioral, social, biomedical, applied, and formal sciences and topics that may involve basic, translational, or clinical research. The NIH Director's New Innovator Award Program complements other ongoing efforts by NIH and its Institutes and Centers to fund early stage investigators. The NIH Directors New Innovator Award Program is a component of the High-Risk, High-Reward Research (HRHR) Program of the NIH Common Fund.

This funding opportunity supports innovative research to measure brain changes over time in people of all ages, including those with cognitive or emotional challenges, to better understand brain development and aging.

The NIH Director's Early Independence Award supports rigorous and promising junior investigators who wish to pursue independent research soon after completion of their terminal doctoral degree or post-graduate clinical training, thereby forgoing the traditional post-doctoral training period and accelerating their entry into an independent research career. For the program to support the best possible researchers and research, applications are sought which reflect the full diversity of the research workforce. To support innovative and novel research across the vast NIH mission, individuals from diverse backgrounds (including those from underrepresented groups; see Notice of NIHs Interest in Diversity) and from the full spectrum of eligible institutions in all geographic locations are encouraged to apply to this Notice of Funding Opportunity. In addition, applications in all topics relevant to the broad mission of NIH are welcome, including, but not limited to, topics in the behavioral, social, biomedical, applied, and formal sciences and topics that may involve basic, translational, or clinical research. The NIH Director's Early Independence Award is a component of the High-Risk, High-Reward Research program of the NIH Common Fund.

This funding opportunity supports researchers from various fields in developing innovative methods to study brain changes over time, focusing on both healthy individuals and those with specific cognitive or emotional challenges.

This funding opportunity supports researchers conducting small clinical trials to develop and test innovative devices for recording and stimulating the human brain, aimed at treating central nervous system disorders.

This Notice of Funding Opportunity Announcement (NOFO) invites applications to develop and maintain a (NSC3). The goal of the NSC3 is to provide logistical and organization support of the NSC. Applicants should be familiar with Nathan Shock Centers (NSC) activities, but they do not need to be part of an NSC. Major activities of the proposed NSC3 will include improving visibility of the NSC nationally and internationally, improving collaboration and coordination among NSC, enhancing NSC training activities, facilitating the sharing of resources, and interacting with NIA and NSC to develop strategies and plans for further development. The successful application will include a plan to improve transparency and the interactions of NSC with the research community. It should also leverage existing bioinformatics resources. The NSC3 director will be a participant in the NIA's Research Centers Collaborative Network.

This NOFO invites applications for the Nathan Shock Centers of Excellence in Basic Biology of Aging (NSC). These Center grants will provide funding for leadership, training, research, and outreach activities that will increase and disseminate scientific knowledge in areas supported by the NIA's Division of Aging Biology. The NSC were created in 1995 in honor of Nathan Shock, founding head of the NIH Gerontology Research Center. The NSC provide, both within and beyond their institutions, intellectual leadership and innovation; training; pertinent service cores focused on the needs of the field; and opportunities for research career development. They each collaborate substantially with other NSC and other NIA-funded Centers through the Research Centers Collaborative Network (RCCN). The NSC awards are intended for institutions committed to research on the basic biology of aging, The awards will facilitate further sustained progress on basic research on aging biology, either overall or on a key area within the field. Research Objectives To achieve the objectives above, applicants may propose a sustained research program focused on aging biology as a general term, or by identifying a well-defined and focused area within the field. If a focused research area is selected, service core activities (see below) should be consistent with that selection. Reviewers will be instructed to accept either approach (general or focused) as responsive to this NOFO. It is crucial to the design of each NSC that applicants specify the goals to be achieved within the five-year award period, to provide a plan to reach these goals, and to outline a method to evaluate progress toward these goals. The selection of core activities (see below) should follow from these considerations. Applications in response to this NOFO must include the following: Provide intellectual leadership in biology of aging research, serving as a resource for experimental design and guidance on the appropriate uses and limitations of aging metrics. Support multidisciplinary and translational research. Provide access to technologies through the cores. Develop technology (in the cores) for emerging areas of research in biology of aging. Leverage local institutional resources. Collaborate with other NSC and The Nathan Shock Centers Coordinating Center (NSC3) on multi-center research education, mentorship, and outreach programs. Interface with other NSC, the NSC3, and other NIH funded centers directly (as appropriate) or through the NIA-supported RCCN. To support these goals, each application must include the following: A core to support administrative functions. This core will manage outreach activities including courses, lectures and symposia – if such activities are proposed. This core will also be responsible for advertising the activities of the NSC, through development of a functional website, and participation in a common Data Coordination Center (see below). The leader of this core must be a PD/PI. A research development core to support pilot/feasibility projects, as well as provide support for investigators entering the field of biology of aging research. At least two research core activities uniquely focused on issues of interest to the biology of aging. These are further discussed below. Support for Research Each NSC may select an area of research focus from a broad range of topics, including, but not limited to, the following examples: Drivers of aging (often considered hallmarks); Metrics of aging, including biomarkers, clocks, computer-based modeling, imaging, etc.; Life course approaches to aging biology; Species-differences and similarities in aging; Medicinal chemistry for development of gerotherapeutics and geroprotective pharmacological interventions; Development and dissemination of new technologies to retain age-of-donor traits for in vitro systems; Facilitation of translation to clinical research; and Support for biology of aging research in IDeA states. Support for Outreach and Education Each NSC should place special emphasis on career development, engaging the public and providing education around the topic of aging biology, including, but not limited to the following examples: Mini-sabbaticals for mid-career and senior investigators (emphasizing new-to-aging research); Community engagement – inform about biology of aging and opportunities for citizen science; Webinars; and Symposia. Applicants must provide plans for the following elements: Leadership succession; Fostering an inclusive and accessible research training environment; and Evaluation: Applications must include a clear description of their objectives and a plan for evaluating the NSC, including all activities supported by the NSC, in line with the broader NSC program goals. The application must specify baseline metrics of NSC activities (e.g., numbers and characteristics of workshop participants, scientific dissemination, databases, networking opportunities with other funders, users of resources, etc.), as well as clearly defined milestones with metrics to gauge the short- or long-term success of the NSC in achieving its objectives. Wherever appropriate, applicants are encouraged to obtain feedback from participants to help identify weaknesses and to provide suggestions for improvements. The NSC evaluation plan should focus on the activities of the NSC, not the entire NSC program. NIH will evaluate the entire NSC program and NSC in five years, including the role of the NSC in fostering the success of the program. Based on the review, NIA will evaluate the effectiveness of the program, and determine whether to (a) continue the program as currently configured, (b) continue the program with modifications, or (c) discontinue the program after sunset and review period. Pre-Application Webinar A webinar is planned to provide prospective applicants the opportunity to understand and ask questions on the scientific scope of this NOFO and technical details for applying. The webinar will be open to all prospective applicants. Participation in the webinar is not a prerequisite to applying to this NOFO, but prospective applicants will need to register in order to participate. Prospective applicants are also encouraged to submit their questions in advance of the webinar; further details on where to submit the questions will be provided once the webinar has been scheduled. Please refer to the registration page for further details on the pre-application webinar, including the time and date and registration information.

This grant provides funding for research projects that test strategies to reduce suicide risk by promoting safe storage of lethal means, such as firearms, in healthcare and community settings.

"Fluctuating cognition can occur in many types of dementia and is a core clinical feature of Dementia with Lewy Bodies. Cognitive fluctuations can last from seconds to days, are unpredictable (e.g., do not just occur in the evenings, as with sun-downing), and are associated with poor daily functioning for the patient. A number of small studies have suggested that cognitive fluctuations in subjects with dementia may be related to epileptiform discharges and impaired oscillatory activity on EEG, but it is not clear that these are the only factors involved in patient populations that often experience dysautonomia, orthostasis, and sleep disturbances. The etiology of cognitive fluctuations may be multi-factorial and may vary in different dementia populations. Understanding the physiology related to cognitive fluctuations is a critical next step to the development of treatment approaches and improving quality of life for these patients. This initiate would encourage research that will better characterize the physiology responsible for cognitive fluctuations in ADRD populations. Given their variable appearance and time course, it is anticipated that wearable digital devices will be important for capturing fluctuations in a timely fashion, and applicants should consider incorporating those device(s) capable of acquiring the relevant data to support the hypothesized mechanism(s). Applicants may focus on assessing multiple mechanisms in a specific ADRD population, or may chose to compare mechanisms across multiple types of ADRDs. "