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Grants for Small Businesses

Explore 4,852 grant opportunities available for Small Businesses

Exploratory Clinical Neuroscience Research on Substance Use Disorders (R61/R33 Clinical Trial Optional)
$500,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 9, 2025

Date Added

Apr 10, 2023

This funding opportunity supports innovative clinical research to explore the brain mechanisms behind substance use disorders, targeting a wide range of researchers and institutions dedicated to addressing addiction challenges.

Education
State governments
Exploratory Clinical Neuroscience Research on Substance Use Disorders (R61/R33 Basic Experimental Studies with Humans (BESH) Required)
$500,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 9, 2025

Date Added

Apr 10, 2023

This funding opportunity provides financial support for innovative research aimed at understanding the brain mechanisms behind substance use disorders, targeting a wide range of applicants including universities, nonprofits, and private organizations.

Education
State governments
Development and Application of PET and SPECT Imaging Ligands as Biomarkers for Drug Discovery and for Pathophysiological Studies of CNS Disorders (R01 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 6, 2025

Date Added

Apr 7, 2023

This grant provides funding for researchers to develop and test advanced imaging tracers that can help understand and treat mental health and neurodegenerative disorders in humans.

Health
State governments
BRAIN Initiative: Exploratory Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (R61 Basic Experimental Studies with Humans Required)
$2,100,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Mar 31, 2023

This funding opportunity supports early-stage research projects that use invasive techniques to study human brain activity, aiming to advance our understanding of cognition and behavior.

Science and Technology
Public and State controlled institutions of higher education
Pulmonary Outcomes and Sequelae after Treatment-TB (POST-TB) (R01 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 7, 2025

Date Added

Mar 30, 2023

This funding opportunity supports research on the long-term lung health effects of tuberculosis treatment, particularly for individuals co-infected with HIV, aiming to improve understanding and management of post-TB lung disease.

Health
State governments
NIDCR Research Grants for Analyses of Existing Genomics Data (R01) (Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 7, 2025

Date Added

Mar 28, 2023

This funding opportunity supports researchers analyzing existing genomic data related to dental, oral, and craniofacial health to address research gaps and improve health outcomes.

Health
State governments
NIDCR Small Research Grants for Analyses of Existing Genomics Data (R03 Clinical Trial Not Allowed)
$100,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 7, 2025

Date Added

Mar 28, 2023

This funding opportunity supports small-scale research projects that analyze existing genomic data to advance understanding of dental, oral, and craniofacial health, particularly focusing on health disparities and biological pathways for intervention.

Health
State governments
Instrumentation Grant Program for Resource-Limited Institutions (S10 - Clinical Trial Not Allowed)
$250,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jul 3, 2025

Date Added

Mar 21, 2023

This funding opportunity provides financial support for under-resourced U.S. institutions to acquire advanced scientific instruments that enhance biomedical research and education, particularly for students from diverse and underserved backgrounds.

Health
State governments
Research With Activities Related to Diversity (ReWARD) (R01 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 5, 2024

Date Added

Mar 16, 2023

This funding opportunity supports researchers with a strong background in promoting diversity, equity, inclusion, and accessibility in biomedical fields, enabling them to conduct scientific research while advancing DEIA initiatives within the academic and scientific communities.

Education
State governments
Avenir Award Program for Research on Substance Use Disorders and HIV (DP2 Clinical Trial Optional)
$375,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Aug 15, 2025

Date Added

Mar 10, 2023

This funding opportunity supports early-stage researchers in the U.S. who are developing innovative projects to address the intersection of substance use disorders and HIV, with the goal of improving treatment and reducing incidence in affected populations.

Education
State governments
Centers for AIDS Research (P30 Clinical Trial Not Allowed)
$3,250,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Aug 4, 2025

Date Added

Mar 9, 2023

This funding opportunity provides substantial financial support to higher education institutions and nonprofit organizations to establish collaborative centers that advance research and resources for HIV/AIDS.

Education
State governments
Developmental Centers for AIDS Research (P30 Clinical Trial Not Allowed)
$1,000,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Aug 4, 2025

Date Added

Mar 9, 2023

This funding opportunity provides significant financial support to U.S. higher education institutions and research organizations with established HIV/AIDS research programs, enabling them to enhance their research infrastructure and foster interdisciplinary collaboration in the fight against HIV/AIDS.

Education
State governments
Biomedical Technology Optimization and Dissemination Center (BTOD)(RM1-Clinical Trial Not Allowed)
$850,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 27, 2026

Date Added

Mar 7, 2023

This funding opportunity provides financial support to U.S.-based organizations for the late-stage development and dissemination of biomedical technologies that have shown laboratory feasibility, aiming to enhance their accessibility and usability in the research community.

Health
State governments
NIMH Mentoring Networks for Mental Health Research Education (R25 Clinical Trial Not Allowed)
$200,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

May 25, 2025

Date Added

Mar 3, 2023

This funding opportunity supports the creation of mentoring networks that provide professional development and career guidance for graduate students, postdoctoral scholars, and early-career researchers in mental health, helping them advance towards independent research careers.

Health
State governments
NIMH Research Education Programs for Psychiatry Residents (R25- Independent Clinical Trial Not Allowed)
$200,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

May 25, 2025

Date Added

Mar 3, 2023

This funding opportunity supports U.S. institutions in developing educational programs for psychiatry residents to enhance their research skills and encourage careers in mental health research.

Health
State governments
NIMH Short Courses for Mental Health Related Research (R25 -Independent Clinical Trial Not Allowed)
$200,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

May 25, 2025

Date Added

Mar 3, 2023

This funding opportunity supports short courses that train researchers in advanced mental health research skills, targeting graduate students, postdoctoral scholars, and early-career investigators across the nation.

Health
State governments
Genomic Community Resources (U24 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 25, 2026

Date Added

Mar 1, 2023

This funding opportunity supports the development and sharing of valuable genomic resources for researchers and organizations involved in basic and clinical genomics, ensuring broad access and community engagement.

Education
State governments
NIH SIREN Neurologic Clinical Trials (UG3/UH3 - Clinical Trial Required)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 7, 2024

Date Added

Feb 8, 2023

This funding opportunity announcement (FOA) encourages applications for multi-center clinical trials focused on neurological emergencies. Successful applicants will collaborate and conduct the trial within the NIH SIREN Network. The NIH SIREN Clinical Coordinating Center (CCC) will work with the successful applicants to implement the proposed trial efficiently and the SIREN Data Coordinating Center (DCC) will provide statistical and data management support. The NIH SIREN hubs and their affiliated clinical sites will provide on-site implementation of the clinical protocols.The NIH SIREN Network will also be uniquely poised to collaborate with other US and international consortia necessary to conduct larger, definitive trials of promising interventions for neurological emergencies.Multi-center clinical trials in stroke treatment, recovery, or prevention supported by NINDS will be conducted in the NIH StrokeNet, and not within SIREN. Applicants do not need to be part of the existing SIREN infrastructure to apply under this FOA.

Health
State governments
Collaborative Program Grant for Multidisciplinary Teams (RM1 - Clinical Trial Optional)
$1,500,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

May 27, 2026

Date Added

Feb 3, 2023

This funding opportunity supports multidisciplinary research teams in the U.S. working on complex biomedical questions, with a focus on advancing foundational biological processes and addressing critical health issues.

Health
State governments
NIMHD Exploratory/Developmental Research Grant Program (R21 - Clinical Trial Optional)
$200,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 16, 2025

Date Added

Feb 1, 2023

This funding opportunity supports innovative research projects aimed at improving health outcomes and reducing disparities for minority populations in the U.S. through short-term studies and pilot interventions.

Health
State governments

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