Grants for Special District Governments

This funding opportunity supports a wide range of organizations in developing innovative drug therapies for Alzheimer's disease and related dementias, focusing on non-traditional treatment targets and requiring collaboration with NIH throughout the clinical trial process.

This funding opportunity supports research projects aimed at improving diagnostic safety and reducing errors in outpatient healthcare settings, particularly for underserved populations.

This notice of funding opportunity (NOFO) is the first in an anticipated series of Landowner Support for Forest Resilience NOFOs. Landowner Support for Forest Resilience is currently funded by four Inflation Reduction Act (IRA) provisions (Public Law No: 117-169. Subtitle D, Sec. 23002(a) (1 ), (2), (3), and (4)), which encompass cost share and payment incentives for forestry practices and support participation of underserved landowners and small-acreage landowners (owning less than 2,500 acres) in emerging private markets for climate mitigation or forest resilience. Landowner Support for Forest Resilience falls under the USDA Forest Service's existing Landscape Scale Restoration Program, as authorized under Section 13A of the Cooperative Forestry Assistance Act of 1978 (16 U.S.C. 2109a). This program advances the Biden-Harris Administration's Justice40 Initiative. Established by Executive Order 14008 on Tackling the Climate Crisis at Home and Abroad, the Justice40 Initiative has made it a goal that 40 percent of the overall benefits of certain federal investments, such as climate, clean energy, and other areas, flow to disadvantaged communities. This notice of funding opportunity (NOFO) solicits proposals for two IRA provisions: Subtitle D, Sec. 23002 (a)(2) and Subtitle D, Sec. 23002 (a)(3). These provisions provide the USDA Forest Service with funding to:Support the participation of underserved forest landowners in emerging private markets for climate mitigation or forest resilience.Support the participation of forest landowners who own less than 2,500 acres of forest land in emerging private markets for climate mitigation or forest resilience.

This funding opportunity supports experienced researchers looking to expand their expertise or shift their career focus through advanced training and research experiences at various institutions.

This funding opportunity supports research aimed at understanding and reducing diagnostic errors in outpatient healthcare settings, particularly focusing on underserved populations and the factors contributing to these errors.

This grant provides financial support and mentorship for outstanding graduate students in the U.S. who are pursuing a PhD in cancer research, helping them transition to postdoctoral training and independent research careers.

The goal of this concept is to support exploratory research and preliminary interventions to address the interrelated and compounding contextual factors that contribute to substance use and HIV risk among sexual trafficking survivors. This would be accomplished through research that builds new interventions and models of care that can effectively engage ST survivors in care for SUD, HIV, trauma, and other mental health outcomes and addresses key structural and social determinants of health that contribute to risk for ST as well as barriers to and facilitators of escaping continued exploitation.

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) invites applications for projects to expand, improve, or transform the utility of mammalian cancer and tumor models for translational research. With this NOFO, the NCI intends to encourage submission of projects devoted to demonstrating that mammalian models or their derivatives used for translational research are robust representations of human biology, are appropriate to test questions of clinical importance, and provide reliable information for patients' benefit. These practical goals contrast with the goals of many mechanistic, NCI-supported R01 projects that employ mammals, or develop and use mammalian cancer models, transplantation tumor models, or models derived from mammalian or human tissues or cells for hypothesis-testing, non-clinical research. Among many other possible endeavors, applicants in response to this FOA could propose demonstrations of how to overcome translational deficiencies of mammalian oncology models, define new uses of mammalian models or their genetics for unexplored translational challenges, advance standard practices for use of translational models, test approaches to validate and credential models, or challenge current practices for how models are used translationally

This funding opportunity provides substantial financial support to state and local public health agencies to modernize their operations, expand their workforce, and improve data systems, ultimately enhancing public health services and addressing health disparities.

This grant provides funding for research projects that implement screening and intervention strategies for alcohol, tobacco, and drug use among adult populations facing health disparities, such as racial minorities and low-income communities.

This funding opportunity supports researchers in validating biomarkers for Alzheimer’s disease and related dementias to improve diagnosis, treatment, and monitoring, particularly in diverse populations.

This funding opportunity supports students enrolled in dual-degree medical and research training programs, helping them develop into independent physician-scientists through mentored research and clinical training.

This Notice of Funding Opportunity (NOFO) aims to support research on interdisciplinary population approaches to increasing awareness of the relationship between alcohol and cancer risk, understanding and changing social norms related to alcohol consumption, developing and/or evaluating alcohol policy approaches, and the development, testing, and implementation of population-level interventions to reduce alcohol-related cancer risk. Applications that address multiple levels of consumption, such as moderate and heavy drinking, are of particular interest, as well as those focusing on alcohol use disorder (AUD) from the perspective of cancer prevention and control. Proposals addressing understudied areas are encouraged, as is attention to underrepresented minority (URM) populations experiencing cancer and alcohol-related disparities such as American Indian, Alaskan Native, and sexual and gender minority populations.

This grant provides funding to support the development of comprehensive strategies for creating next-generation HIV treatments and prevention methods, helping researchers prepare for FDA approval processes.

This notice of funding opportunity (NOFO) is the first in an anticipated series of Landowner Support for Forest Resilience NOFOs. Landowner Support for Forest Resilience is currently funded by four Inflation Reduction Act (IRA) provisions (Public Law No: 117-169. Subtitle D, Sec. 23002(a) (1 ), (2), (3), and (4)), which encompass cost share and payment incentives for forestry practices and support participation of underserved landowners and small-acreage landowners (owning less than 2,500 acres) in emerging private markets for climate mitigation or forest resilience. Landowner Support for Forest Resilience falls under the USDA Forest Service's existing Landscape Scale Restoration Program, as authorized under Section 13A of the Cooperative Forestry Assistance Act of 1978 (16 U.S.C. 2109a). This program advances the Biden-Harris Administration's Justice40 Initiative. Established by Executive Order 14008 on Tackling the Climate Crisis at Home and Abroad, the Justice40 Initiative has made it a goal that 40 percent of the overall benefits of certain federal investments, such as climate, clean energy, and other areas, flow to disadvantaged communities. This notice of funding opportunity (NOFO) solicits proposals for two IRA provisions: Subtitle D, Sec. 23002 (a)(2) and Subtitle D, Sec. 23002 (a)(3). These provisions provide the USDA Forest Service with funding to:Support the participation of underserved forest landowners in emerging private markets for climate mitigation or forest resilience.Support the participation of forest landowners who own less than 2,500 acres of forest land in emerging private markets for climate mitigation or forest resilience.

The Administration for Children and Families (ACF) plans to solicit applications for awards to support researchers conducting secondary analyses of data to address key questions of relevance to the Child Care and Development Fund (CCDF). CCDF is the primary federal funding source for child care subsidies and aims to help eligible low-income working families access child care and to improve the quality of child care for all children. CCDF also aims to improve implementation of high-quality child care programs to 1) promote childrens healthy development and learning and 2) support the education, training, and well-being of child care workers through efforts that include child care licensing, quality rating and improvement systems (QRIS) and professional development opportunities. Analyzing existing data sets may provide researchers an efficient and cost-effective method for answering critical research questions of relevance to CCDF. Findings from these awards are intended to inform policy, program administration, and future research.Topics of particular interest to ACF may include, but are not limited to: reducing barriers to access and/or improvements in access to child care and early education, particularly high-quality programs for those most in need of services; consumer education; recruiting and retaining a qualified early care and education (ECE) workforce; stabilizing the supply of high-quality care and education programs; improving teacher and caregiver competencies through professional development; supporting workforce well-being; and, approaches to engage, support, and meet the needs of families. Data sets of particular interest to ACF may include, but are not limited to, the 2019 National Survey of Early Care and Education and state- or territory-level workforce registry, subsidy, Quality Rating and Improvement System (QRIS), licensing, monitoring, Child Care Resource and Referral (CCR), or Preschool Development Grants B-5 data.

This opportunity provides access to valuable biospecimens from a major study on brain development in children, aimed at researchers investigating adolescent health across various institutions and organizations.

This funding opportunity supports research projects that explore how patients' beliefs and expectations about cancer treatment can improve symptom management, particularly for underserved populations facing unique challenges in care.

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) solicits applications for identification of small molecules that function to elucidate the biology of disease as chemical probes or function as agonists or antagonists of disease target(s) for therapy or immunotherapy. The NOFO is intended to support discovery research for the identification of validated hits relevant to health-related outcomes of participating NIH Institutes. Stages of discovery research covered by this NOFO include: 1) assay development for specific biological targets and disease mechanisms relevant to the mission of participating NIH Institutes with the intent to screen for small molecule compounds that show potential as probes for use in advancing knowledge about the known targets, identifying new targets, or as pre-therapeutic leads; 2) screen implementation high throughput target-focused approaches or moderate throughput phenotypic- and fragment-based approaches to identify initial screening hits; 3) hit validation, including implementation of secondary assays that are orthogonal to the primary assay, advanced cheminformatics analysis and initial medicinal chemistry inspection to prioritize the hit set, and follow-up assays to characterize mode and mechanism of action of the validated hits; 4) hit-to-lead optimization, including SAR to optimize target engagement, selectivity and to minimize chemical liabilities, ADME, PK and PD studies, and, if appropriate, in vivo modeling to test efficacy or biological effects.

The "HEAL Initiative: Understanding Individual Differences in Human Pain Conditions" grant aims to fund research that explores the differences in how individuals experience pain, with the goal of improving personalized pain treatment strategies and understanding the impact of factors like additional health conditions or substance use.