Grants for Special District Governments

The URGenT network grant aims to speed up the development and clinical testing of gene-based therapies for ultra-rare neurological or neuromuscular disorders, with the ultimate goal of initiating a clinical trial.

This funding opportunity supports researchers in developing new screening methods and treatments for serious genetic conditions in newborns that could greatly benefit from early detection and intervention.

This grant provides access to specialized resources and expertise for researchers developing gene-based therapies for extremely rare neurological disorders, helping them prepare for regulatory submissions and advance their therapeutic projects.

This funding opportunity supports innovative research on new screening methods and treatments for severe conditions detectable in newborns, aimed at improving early detection and health outcomes.

This funding opportunity provides financial support for researchers to develop innovative screening methods and therapies for newborn conditions, aiming to improve early detection and management of potentially serious health issues in infants.

The "Modulating Human Microbiome Function to Enhance Immune Responses Against Cancer" grant aims to fund preliminary research into how the human microbiome affects the body's immune response to cancer, with a focus on how specific microbes or their byproducts can either increase or prevent tumor formation, and how the amount, timing, and duration of beneficial microbes can impact their effectiveness.

This grant provides funding for researchers to explore how the human microbiome influences immune responses to prevent cancer, aiming to identify new strategies for cancer prevention.

This grant provides funding for researchers to develop and validate new diagnostic tools and treatment measures for Functional Neurological Disorders, aiming to improve clinical trial readiness and patient care.

The National Institute for Occupational Safety and Health (NIOSH), Centers for Disease Control and Prevention (CDC), invites grant applications for Training Project Grants (TPGs) that are focused on occupational safety and health training. NIOSH is mandated to provide an adequate supply of qualified personnel to carry out the purposes of the Occupational Safety and Health Act, and the TPGs are one of the principal means for meeting this mandate. The majority of TPGs are in academic institutions that provide high quality training in the core occupational safety and health disciplines of industrial hygiene (IH), occupational health nursing (OHN), occupational medicine residency (OMR), occupational safety (OS), as well as allied disciplines. NIOSH also funds non-academic programs to meet specific training needs of targeted populations including firefighters, commercial fishermen and occupational health and safety interns.

This Funding Opportunity Announcement (FOA) will support extramural research to investigate and mitigate challenges facing clinical assay development and subsequent analytical validation due to preanalytical variability in tumor tissue biopsies, blood biospecimens utilized as liquid biopsies", or other biospecimens as described in this FOA. Extramural research funded under this FOA may include investigations of preanalytical variability associated with the procurement and study of small biopsies (core biopsies, small excision samples), blood utilized for "liquid biopsies", tissue swabs, tissue secretions, pleural and esophageal aspirates, feces, or bodily fluids like sweat, urine, CSF, breast milk and saliva. Investigator-designed experiments will explore how different biospecimen preanalytical conditions affect emerging and clinically relevant biomarkers quantified by a variety of testing platforms. The results from this research program will improve the understanding of how analytical quantification of clinically relevant biomarkers is affected by variation in biospecimen collection, processing, and storage procedures. The overall goal is to expedite biomarker clinical assay development through evidence-based standardization of biopsy handling practices.

This funding opportunity provides financial support for research projects aimed at improving antibiotic use and reducing infections in healthcare settings, particularly in hospitals, long-term care facilities, and outpatient environments.

This funding opportunity provides financial support for research projects aimed at improving antibiotic use, reducing the spread of antibiotic-resistant bacteria, and preventing healthcare-associated infections across various healthcare settings.

The "Neuromodulation/Neurostimulation Device Development for Mental Health Applications" grant aims to fund the development of innovative brain stimulation devices or significant hardware/software enhancements to existing FDA-approved devices, with a focus on improving precision and delivery, for the treatment of mental health disorders.

The "Exploratory Grants in Cancer Control" is a funding opportunity aimed at supporting early-stage research projects that focus on understanding and controlling cancer through behavior modification, screening, and the development of innovative techniques or methodologies that could significantly impact the field of cancer research.

This grant provides funding for innovative teams to develop or significantly enhance neuromodulation devices aimed at improving treatments for mental health disorders.

This funding opportunity supports interdisciplinary research centers focused on advancing the understanding and treatment of communication disorders, such as hearing and speech issues, through collaborative projects and clinical trials.

This funding opportunity announcement (FOA) invites research projects that seek to model the underlying mechanisms, processes, and trajectories of social relationships and how these factors affect outcomes in health, illness, recovery, and overall wellbeing. Both animal and human subjects research projects are welcome. Researchers proposing basic science experimental studies involving human participants should consider the companion FOA TEMP-14931 "Research on Biopsychosocial Factors of Social Connectedness and Isolation on Health, Wellbeing, Illness, and Recovery (R01 Basic Experimental Studies with Humans Required)".

This funding opportunity announcement (FOA) invites research projects that seek to explain the underlying mechanisms, processes, and trajectories of social relationships and how these factors affect outcomes in human health, illness, recovery, and overall wellbeing. Types of projects submitted under this FOA include mechanistic studies that are classified as clinical trials. Mechanistic studies are defined as studies with the objective to understand the mechanism(s) of action of an intervention, a biological or behavioral process, or the pathophysiology of a disease/condition. See NOT-AT-20-001 and NOT-MH-19-006 for examples of clinical trials that are/are not considered mechanistic studies. Clinical trials that propose to influence a clinical outcome, test safety or feasibility of an intervention, demonstrate the clinical efficacy or effectiveness of an intervention, or analyze the effect size of an intervention on clinical outcomes are ineligible for this FOA. Types of studies that should submit under this FOA include clinical trials that assess biomedical or behavioral outcomes in humans for the purpose of understanding the fundamental aspects of phenomena without specific application towards processes or products in mind. Researchers proposing basic science experimental studies involving human participants should consider this FOAs companion for basic experimental studies with humans, TEMP-14931, Research on Health, Wellbeing, Illness, and Recovery (R01 Basic Experimental Studies with Humans Required). Applications proposing studies that include, but are not limited to, model animal research or observational studies involving humans should submit under the companion FOA, TEMP-14934, "Research on Biopsychosocial Factors of Social Connectedness and Isolation on Health, Wellbeing, Illness, and Recovery (R01 Clinical Trials Not Allowed).

This funding opportunity announcement (FOA) invites research projects that seek to explain the underlying mechanisms, processes, and trajectories of social relationships and how these factors affect outcomes in human health, illness, recovery, and overall wellbeing. Types of projects submitted under this FOA include studies that prospectively assign human participants to conditions (i.e., experimentally manipulate independent variables) and that assess biomedical and/or behavioral outcomes in humans to understand fundamental aspects of phenomena related to social connectedness and isolatedness. NIH considers such studies as prospective basic science studies involving human participants that meet the NIH definition of basic research and fall within the NIH definition of clinical trials (see, e.g., NOT-OD-19-024) Types of studies that should submit under this FOA include studies that prospectively assign human participants to conditions (i.e., experimentally manipulate independent variables) and that assess biomedical or behavioral outcomes in humans for the purpose of understanding the fundamental aspects of phenomena without specific application towards processes or products in mind. Applications proposing studies that include but not limited to model animal research or observational studies involving humans should submit under the companion Clinical Trials Not Allowed version of this FOA.

The purpose of the NIA Career Transition Award (CTA) is to facilitate the transition of mentored researchers to tenure-track faculty conducting research that advances the mission of NIA. This three-year award provides protected time through salary and research support and is targeted at applicants who plan to start a tenure-track faculty position within a year of the award.