NIH Stroke Clinical Trials Network (StrokeNet) Infrastructure National Coordinating Center (NCC) and National Data Management Center (NDMC)

The NIH Stroke Clinical Trials Network Infrastructure - National Coordinating Center and National Data Management Center opportunity is a forecasted federal cooperative agreement from the U.S. Department of Health and Human Services through the National Institutes of Health and the National Institute of Neurological Disorders and Stroke. The opportunity number is RFA-NS-28-003, and the associated Assistance Listing is 93.853, Extramural Research Programs in the Neurosciences and Neurological Disorders. The National Institute of Neurological Disorders and Stroke seeks to continue support for the infrastructure of the NIH Stroke Clinical Trials Network, also known as NIH StrokeNet. The network conducts clinical trials intended to advance acute stroke treatment, stroke prevention, and stroke recovery and rehabilitation across the lifespan. The purpose of NIH StrokeNet is to improve outcomes for people who experience stroke by evaluating promising new therapies for patients with stroke and individuals at risk for stroke. Through this forecasted opportunity, the program expects to encourage applications for two components of the national network infrastructure: a National Coordinating Center and a National Data Management Center. These centers are intended to support the NIH StrokeNet clinical trial network. The opportunity is categorized under Health and uses a cooperative agreement as the funding instrument. The forecast identifies an expected total of two awards. No estimated total program funding, award ceiling, or award floor is provided in the available notice. The opportunity does not require cost sharing or matching. The source does not provide additional spending rules, indirect cost restrictions, subaward limits, or a stated performance period. Eligibility is broad and includes state governments, county governments, city or township governments, special district governments, independent school districts, public housing authorities and Indian housing authorities, federally recognized Native American tribal governments, other Native American tribal organizations, public and state controlled institutions of higher education, private institutions of higher education, nonprofit organizations with or without federal 501(c)(3) status, for profit organizations other than small businesses, small businesses, and other eligible applicants described in the notice. Additional eligible applicants include eligible agencies of the federal government, U.S. territories or possessions, faith-based or community-based organizations, and regional organizations. Applications are not currently being solicited. The notice is a forecast intended to give potential applicants sufficient time to develop meaningful collaborations and responsive applications for the centers. The estimated posting date is December 20, 2027, so the opportunity is presently in an early engagement stage rather than accepting applications. No letter of intent, concept paper, pre-proposal, notice of intent, or other pre-application gating requirement is identified in the provided forecast. The source also does not yet provide application questions, required attachments, review or evaluation criteria, portal-specific submission instructions, or other detailed application components. The estimated application due date is January 25, 2028. The estimated award date is December 1, 2028, and the estimated project start date is also December 1, 2028. The fiscal year identified for the opportunity is 2029. The forecast was issued September 10, 2026 and was last updated September 10, 2026. No recurring annual or other periodic application cycle is stated, so the opportunity is treated as nonrecurring based on the currently available information. Because this is a forecast, the posting and application dates are estimates and may be further defined when the full funding opportunity is posted. The grantor contact identified for questions is the National Institute of Neurological Disorders and Stroke StrokeNet program. The notice instructs interested parties to make contact by email at strokenetinquiry@mail.nih.gov. No individual contact person or telephone number is provided. The available source also does not contain an explicit direct PDF URL for a NOFO, RFA, application package, or guidelines document. Potential applicants therefore have advance notice of the planned competition and its expected timing, but the detailed submission requirements, funding amounts, evaluation criteria, and complete application instructions remain unavailable in this forecast.

Use the forecast period to develop meaningful collaborations and a responsive center application. Align proposed planning with the National Coordinating Center or National Data Management Center role and with NIH StrokeNet's clinical trial mission involving acute stroke treatment, stroke prevention, and stroke recovery and rehabilitation.