Grants for Nonprofits - Education

The Outreach and Restoration Grant Program is a collaborative effort between the Chesapeake Bay Trust and various partners including BGE, Charles County, the City of Baltimore Department of Public Works, and others. This program is designed to foster community engagement, raise awareness, and facilitate on-the-ground restoration projects. Its core mission aligns with increasing knowledge, changing behaviors, and accelerating the stewardship of natural resources within Maryland. The Trust encourages projects that recognize the interconnectedness of environmental and human health, aiming for co-benefits such as improved air quality, access to green spaces, and reduced flooding, alongside direct natural resource improvements. The program targets a diverse range of organizations, encompassing both community-related and environmental-focused missions. Eligible applicants include 501(c)3 private nonprofits, faith-based organizations, community and homeowners associations, public agencies, and educational institutions. The overarching impact goals are to increase public understanding of environmental challenges and solutions, address community environmental health disparities, implement demonstration-scale community-inspired restoration projects, and expand the base of public support for the restoration and protection of Maryland's natural resources. Projects funded through this grant program must meet one or both of two primary goals: engaging specific audiences in community sustainability and environmental health issues through knowledge-building or behavior-change efforts, and accomplishing on-the-ground restoration that enhances the health of Maryland's natural resources, specifically through water quality improvement or habitat enhancement. These priorities are further broken down into four distinct funding tracks: Outreach/Knowledge Building (up to $50,000), Behavior Change (up to $75,000), Restoration (up to $100,000), and Outreach and Restoration (up to $125,000), allowing applicants to focus on their specific expertise and project scope. Expected outcomes and measurable results include increased knowledge and altered behaviors among community members regarding environmental stewardship. On-the-ground restoration projects are expected to yield tangible improvements in water quality and habitat health. The program seeks to demonstrate the effectiveness of community-led stewardship efforts and address local environmental health disparities. By engaging a broad spectrum of organizations and communities, the Chesapeake Bay Trust and its partners aim to build a stronger, more informed base of support for long-term environmental protection and restoration across the state of Maryland.

The NYSCA/GHHN Conservation Treatment Grant is a collaborative initiative between the New York State Council on the Arts (NYSCA) and the Greater Hudson Heritage Network (GHHN). This program offers financial assistance for treatment procedures aimed at stabilizing and preserving objects held in the collections of museums, historical, and cultural organizations across New York State. The grant's mission is aligned with supporting the arts and cultural heritage by safeguarding significant artifacts and ensuring their longevity for public access and historical record. Additional funding from the Robert David Lion Gardiner Foundation specifically supports projects from Long Island and New York City, further extending the reach and impact of this conservation effort. The grant targets nonprofit organizations, including museums, historical organizations, and other cultural institutions that are incorporated in or registered to do business in New York State and own, care for, and exhibit collections to the public. This includes institutions of all sizes, with encouragement for those with smaller budgets to apply. The impact goal is to aid in the stabilization and preservation of cultural objects, thereby contributing to a more inclusive narrative of New York State's history and diverse cultural expression. The program explicitly prioritizes objects involving historically marginalized and underrepresented communities, such as African American/Caribbean, Latino/Hispanic, Asian/Pacific Islander, Middle Eastern, Native American/Indigenous, LGBTQIA, and people with disabilities, to tell a more inclusive story of the state. The funding priorities of the NYSCA/GHHN Conservation Treatment Grant embrace a wide spectrum of cultural expression and artistic pluralism. Organizations are encouraged to demonstrate a holistic commitment to DEIA (diversity, equity, inclusion, and access). The program believes that the objects chosen for conservation reflect what an organization values, therefore, objects and stories that contribute to a more inclusive narrative of New York State are highly valued. This focus aims to ensure that a broader range of cultural heritage is preserved and made accessible to the public, fostering a richer understanding of the state's diverse past. Expected outcomes include the successful conservation of various 3D objects, such as paintings, works on paper, textiles, furniture, frames, sculpture, historical, ethnographic, and decorative objects. Measurable results will be seen in the number of objects treated, the types of communities represented by the conserved objects, and the adherence to professional conservation standards. The grant also supports related costs such as in-state transportation, insurance for treated works, and treatment costs for integral supports, stands, and mounts. For outdoor sculptures, a description of an existing or planned maintenance program is required, indicating a commitment to long-term preservation. The grant operates under the strategic priority of promoting cultural preservation through professional conservation practices, while also advancing diversity, equity, inclusion, and access within the cultural heritage sector. The theory of change is that by providing financial support for the conservation of diverse cultural objects, the program will empower New York State's cultural organizations to tell more inclusive narratives, preserve valuable historical artifacts, and make these collections accessible to a wider public. This will ultimately enrich the understanding of New York's cultural landscape and foster greater engagement with its varied histories.

The Oregon Arts Commission's Arts Learning Grants program aims to foster high-quality projects that enhance learning in and through the arts for K-12 students. This initiative aligns with the foundation's mission by promoting artistic engagement and education, recognizing the vital role of arts in student development. The program seeks to bridge the gap between artists and educators, facilitating a knowledge exchange that enriches both teaching practices and student experiences. The primary beneficiaries of this grant are K-12 students who will gain responsive learning opportunities in the arts. The program also targets artists and educators, fostering collaboration and professional development. The overarching impact goals are to improve the achievement, skills, and attitudes of learners by providing access to high-quality arts education. This focuses on holistic development, recognizing that arts education contributes to academic success, critical thinking, and personal growth. Key priorities for this grant include the quality of learning opportunities, the responsiveness of the project to specific population needs, and the appropriateness of the selected teaching artists' skill sets. Artistic excellence and merit are also critical considerations. The program emphasizes strong project support, evaluating the readiness of staff, the viability of recruitment plans for target populations, and the commitment to supporting teaching artists throughout the project. The clarity and relevance of the project budget are also reviewed to ensure efficient and effective use of funds. Expected outcomes include enhanced artistic skills, improved attitudes towards learning, and increased achievement among K-12 students. Measurable results will be assessed based on the articulation of changes in learners as a result of the project and the viability of the process used to measure these changes. This structured evaluation approach ensures that projects are not only well-intentioned but also demonstrably effective in achieving their stated goals. The Oregon Arts Commission's strategic priority through this program is to strengthen arts education across the state. While a specific "theory of change" is not explicitly detailed, it can be inferred that the commission believes that by investing in high-quality arts learning opportunities and fostering collaboration between artists and educators, K-12 students will experience improved outcomes in their artistic abilities, academic achievement, and personal development, ultimately contributing to a more culturally enriched and educated populace.

The Manhattan Composting Award, offered by the Manhattan Borough, aims to combat climate change by reducing organic waste in the waste stream through supporting composting programs. This initiative aligns with a broader mission to address environmental challenges at the local level by fostering sustainable practices within the community. The grant specifically focuses on promoting composting as an accessible and effective method for waste reduction, thereby contributing to a healthier environment and mitigating the effects of climate change within Manhattan. The primary beneficiaries of this grant are youth, seniors, intergenerational populations, and the broader Manhattan community. The grant seeks to impact these groups by increasing their engagement in composting activities and enhancing their understanding of its importance. The goal is to empower residents with the knowledge and resources to participate in organic waste diversion, leading to a measurable reduction in the volume of organic materials sent to landfills. Project priorities for the Manhattan Composting Award include the establishment and expansion of composting and composting education programs tailored for youth and seniors, as well as initiatives that foster intergenerational participation. Community engagement efforts that highlight the benefits of composting and the diverse options available throughout Manhattan are also a key focus. These priorities underscore a comprehensive approach to integrating composting into the daily lives of residents across different age groups and demographics. The expected outcomes of this grant include a significant increase in the number of composting programs implemented and the level of community participation in these programs. Measurable results will likely involve tracking the volume of organic waste diverted from landfills, the number of individuals educated through composting programs, and the establishment of new composting infrastructure. While a specific theory of change or explicit strategic priorities of the "foundation" (in this case, the Manhattan Borough) are not detailed, the program implicitly operates on the theory that increased community participation and education in composting will directly lead to reduced waste, a cleaner environment, and a more sustainable urban ecosystem. The focus on education and community engagement suggests a belief that empowering residents with knowledge and practical skills is the most effective way to achieve long-term environmental benefits.

This grant provides financial support to New Jersey-based nonprofit organizations focused on history and humanities, helping them address specific operational challenges and enhance their stability through targeted projects.

Poynter Reporting Grants for Transgender Coverage Grant Amount: $10,000 to $15,000 (three grants available) Eligibility: Reporters planning projects on all platforms (online, radio, video, print). Must have attended or watched both Beat Academy Transgender Coverage webinars. If not attended, enroll in the course. Support: One-on-one coaching available as needed. Focus: Strong applications focus on concrete local examples of transgender issues. Focus can be personal, family, community, or state level. Emphasis on a crisp story pitch, clear reporting plan, and evidence of reporting skill. Projects should be completed by December 31, 2024. Application Details: Applications due by May 3, 2024. Winners announced in late May. For questions, email Jon Greenberg at beatacademy@poynter.org. Funding Source: Supported by the Gill Foundation.

The Hampton Roads Community Foundation is offering Community Grants for Health & Wellness to enhance the health of the region's residents. This initiative aligns with the foundation's mission to improve community well-being by addressing critical health disparities. The program focuses on the understanding that various factors, including genetics, education, individual behavior, environment, and access to quality healthcare, contribute to a person's overall health and wellness. The foundation's strategic approach is to support programs that tackle these multifaceted challenges, particularly for under-resourced populations. The primary beneficiaries of this grant program are residents of South Hampton Roads, including specific counties and cities within Virginia, who face health disparities and challenges in accessing quality healthcare. The program targets individuals in Chesapeake, the Eastern Shore of Virginia (Accomack and Northampton counties), Franklin, Isle of Wight County, Norfolk, Portsmouth, Suffolk, and Virginia Beach. The impact goal is to improve the health status of these populations by increasing access to essential health services and promoting healthy behaviors. The program prioritizes efforts that support participant access to primary, dental, and/or mental/behavioral health services, including substance/drug abuse treatment. A significant focus is also placed on sustained programs that encourage healthy behaviors known to reduce chronic diseases such as Type II diabetes, heart disease, and lung disease, especially in populations with high rates of health disparity. Preference will be given to programs that emphasize improving participants' health literacy, indicating a strategic focus on empowering individuals with knowledge to make informed health decisions. Expected outcomes include individuals with health disparities connecting with a medical home and receiving care/treatment that leads to an improved health status. For oral care programs, the outcome is that individuals complete a dental treatment plan. Improved behavioral health needs or conditions of clients are also a key outcome. Measurable results will include participants increasing their knowledge of chronic disease conditions and exhibiting healthy behaviors that lead to improved health, thereby contributing to the foundation's broader theory of change which posits that increased access, education, and behavioral changes will lead to a healthier community.

This funding opportunity supports public humanities projects in Iowa that foster community engagement and educational programming about the human experience, available to individuals, nonprofits, local governments, and higher education institutions.

This notice is subject to availability of funding. A. PROGRAM DESCRIPTION U.S. Embassy Belgrade of the U.S. Department of State announces an open competition for organizations to submit applications for the University Partnership Program. Please follow all instructions below. Priority Region: Serbia Program Objectives: The U.S. Embassy works to assist the Serbian people to strengthen democracy, rule of law, and the protection of human rights; help fight brain drain and advance the countrys economic development; promote regional stability and cooperation; cooperate with international partners to combat crime, terrorism, human trafficking, and other global challenges; and make further progress towards Serbias accession into the European Union. We also strive to explain U.S. policies, culture, society, and values to Serbian audiences and deepen ties between our two countries. University Partnership proposals should support these goals while facilitating lasting connections between Serbian and American institutions of higher education. Proposals can involve in-person and/or virtual exchanges for students, faculty, and/or administrators as well as any of the following activities: curriculum development; needs assessments; joint online courses; joint research projects; development of a joint degree program; development of a study abroad program; sharing of best teaching practices and instructional methods; support for participation in academic conferences or student competitions (e.g., moot court, Model U.S. Congress, Model United Nations); establishing an American Studies course or academic program; setting up a center focused on American Studies; and/or establishing or strengthening a career development center or a research and development center. Participants and Audiences: Participants or primary audiences for university partnership proposals should be Serbian and American students, professors/academics, and/or administrators. Depending on focus, projects may have secondary audiences or beneficiaries including media, civil society organizations or wider professional audiences, which you may note in the proposal. If your project idea might involve citizens or any other countries, check D.7 in the full text of the NOFO to understand restrictions on funding. B. FEDERAL AWARD INFORMATION Length of performance period: 6 to 30 months (including the evaluation) Number of awards anticipated: 1-5 awards (dependent on amounts) Award amounts: awards may range from a minimum of $25,000 to a maximum of $300,000. For returning applicants to the University Partnership Program, (previous grantees seeking additional support) awards will be capped at $75,000. Total available funding: $450,000 Type of Funding: FY23/24 Economic Support Funds under the Foreign Assistance Act. Anticipated program start date: Flexible, but not earlier than September 1, 2024. Cost Sharing or Matching: Cost sharing is allowed but not required and will not impact funding decisions. While filling out the application, you will be required to tell us whether you are also receiving funding from other donors for your project. Please be aware, however, that you must be able to carry out all the activities described in your application with the funding you receive, even if the contributions from other donors or other funding sources fail to materialize. C. APPLICATION AND SUBMISSION INFORMATION Requesting the Application Package: Application forms required below are available at https://rs.usembassy.gov/grants-programs and in the Related Documents Tab. Content and Form of Application Submission: Please follow all instructions below carefully. Proposals that do not meet the requirements of this announcement or fail to comply with the stated requirements will be ineligible. Content of Application Please ensure: The proposal clearly addresses the goals and objectives of this funding opportunity All documents are in English All budgets are in U.S. dollars All pages are numbered All documents are formatted to 8 x 11 paper, and All Microsoft Word documents are single-spaced, 12 point Calibri font, with a minimum of 1-inch margins. The following documents are required: 1. Mandatory application forms SF-424 (Application for Federal Assistance organizations) SF-424A (Budget Information for Non-Construction programs) SF-424B (Assurances for Non-Construction programs) (note: the SF-424B is only required for individuals and for organizations not registered in SAM.gov) 2. Grant Application Form for FY2024 (Fiscal year 2024). Note: Detailed instructions for filling out the grant application are included with the form. 3. Budget Justification Narrative (Excel Spreadsheet): After filling out the SF-424A Budget (above), use the Excel spreadsheet template to describe and explain each of the budget expenses in detail. See section H. Other Information: Guidelines for Budget Submissions below for further information. 4. Attachments: 1-page CV or resume of key personnel who are proposed for the program Letters of support from program partners describing the roles and responsibilities of each partner If your organization has a Negotiated Indirect Cost Rate Agreement (NICRA) and includes NICRA charges in the budget, your latest NICRA should be included as a PDF file. Official permission letters, if required for program activities. Required Registrations: All organizations, whether based in the United States or in another country, must have a Unique Entity Identifier (UEI) and an active registration with the SAM.gov. To be eligible for consideration, every Serbia-based applicant organization must also be registered in the territory of the Republic of Serbia with the Agencija za privredne registre (APR), or the relevant court. Submission Dates and Times: Applications are due no later than May 15, 2024. Funding Restrictions: You may NOT apply for a grant from PDS if your project: Involves partisan political activity; Involves charitable activities and/or the distribution of humanitarian aid; Is a fundraising campaign; Is commercial in nature, i.e., you or a project partner are making money from this project, or the activity supports a current or future business or entrepreneurial venture; Involves the provision of health care services, childcare, food subsidies, or other social services to populations. This funding opportunity aims to support specific projects with objectives which can be achieved within a set timeframe. We will not accept applications which are aimed more broadly at supporting your organizations usual or typical daily activities and operations. Those will be deemed technically ineligible and will not be considered for funding by the review committee. Other Submission Requirements: All application materials must be submitted by email to BelgradeUniP@state.gov IF PDS does not receive a complete project proposal at the above address by the deadline, it will be considered technically ineligible and will not be considered for funding. Review and Selection Process: A review committee will evaluate all eligible applications. You may be asked to submit additional information and/or a revised budget. Please also be aware that, depending on the availability of funding, PDS might be able to fund only part of the budget that you have requested. Anticipated Announcement and Federal Award Dates: PDS anticipates that final funding decisions will be made by June 30, 2024. D. FEDERAL AWARDING AGENCY CONTACTS If you have any questions about the grant application process, please contact: BelgradeUniP@state.gov. The full text of the NOFO and the required documents are available at https://rs.usembassy.gov/grants-programs/ and in the Related Documents tab. Information Session. PDS will hold a virtual information session on April 17, 2024, at 15:00 (3 pm) Central European time to discuss this funding opportunity and to answer questions from potential applicants. Please contact PDS at BelgradeUniP@state.gov for details.

Title II Juvenile Justice Council grants are specifically awarded to local juvenile justice councils to implement programs, policies and practices that improve the effectiveness of local juvenile justice systems, reduce unnecessary juvenile justice system involvement and/or analyze and reduce Racial and Ethnic Disparities (RED) in each council’s local system. Because this model of local governance, collaboration and data-driven decision-making has proven effective, the Illinois Juvenile Justice Commission is allocating funding to support local juvenile justice councils and the development of data-driven, collaborative local juvenile justice plans which guide future system improvement efforts. The Illinois Juvenile Court Act provides that each county or group of counties may establish a local juvenile justice council [705 ILCS 405/6-12]. The purpose of this council, according to the Act, is “to provide a forum for the development of a community based interagency assessment of the local juvenile justice system, to develop a county juvenile justice plan for the prevention of juvenile delinquency, and to make recommendations to the county board, or county boards, for more effectively utilizing existing community resources in dealing with juveniles who are found to be involved in crime, or who are truant or have been suspended or expelled from school.” Through juvenile justice councils, the Act prescribes a response to juveniles in conflict with the law that is comprehensive, driven by data and analysis, and collaborative across all systems that touch these youth. As embodied in the Juvenile Court Act, Juvenile Justice Councils provide a structure to ensure that local jurisdictions respond to youth in conflict with the law in a manner which is data-driven, strategic, and focused on serving youth, families and communities in the most effective ways possible. Unfortunately, very few jurisdictions in Illinois have developed councils that operate in the manner envisioned in the Act. In some communities, youth become involved in the juvenile justice system unnecessarily because alternatives do not exist, or are not embedded within the system decision-making process. Because the needs and resources are different in each community in Illinois, a one-size-fits-all approach is not likely to be very effective. Local councils are in the best position to craft solutions that meet the local community’s needs and take into account local resources. Empowering and supporting local juvenile justice councils can also stem the tide of racial and ethnic disparity in the juvenile justice system at the front door and help ensure that no youth enters the juvenile justice system unnecessarily. Such local ownership is the best way to ensure more effective long-term programming and sustained systemic change. This, in turn, will reduce the costs associated with incarcerating youth in correctional facilities, reduce rates of recidivism, reduce the number of crime victims, and ultimately create safer communities in Illinois. Juvenile Justice Youth Serving Programs: The federal Office of Juvenile Justice and Delinquency Prevention (OJJDP) provides funding directly to states through its Title II Formula Grants Program (Title II) to support state and local delinquency prevention, intervention efforts and juvenile justice system improvements. These funds are used to help states implement comprehensive state juvenile justice plans based on detailed studies of needs in their jurisdictions. State Advisory Groups, comprised of members appointed by the governor, set priorities for funded activities. The State Advisory Group for Illinois, the Illinois Juvenile Justice Commission (IJJC), administers the Title II funds. These funds support a broad range of juvenile justice activities at the state and local level that are designed to improve the juvenile justice system through the development of more effective education, training, research, prevention, diversion, treatment, and rehabilitation programs in the area of juvenile delinquency. These programs or projects can be designed to be developed, implemented and evaluated directly or through grants and contracts with public and private agencies. Title II also funds state and local activities designed to ensure and maintain the state's compliance with the Core Requirements of the JJDPA. • Deinstitutionalization of Status Offenders (DSO) • Adult Jail and Lock-Up Removal (Jail Removal) • "Sight and Sound" Separation • Address Racial and Ethnic Disparities (RED); In some communities, youth become involved in the juvenile justice system unnecessarily because alternatives do not exist or are not embedded within the system decision-making process. Because the needs and resources are different in each community in Illinois, a one-size-fits-all approach is not likely to be very effective. Local juvenile justice systems and community-based providers are in prime position to craft solutions and develop youth serving programs that meet the local community's needs and take into account local resources. Empowering and supporting local youth programming can also stem the tide of racial and ethnic disparity in the juvenile justice system at the front door and help ensure that no youth enters the juvenile justice system unnecessarily. Investing in local communities will reduce the costs associated with incarcerating youth in correctional facilities, reduce rates of recidivism, reduce the number of crime victims, and ultimately create safer communities in Illinois.

This funding opportunity provides financial support for early-stage researchers in the U.S. to explore innovative studies on HIV-related health issues, such as comorbidities and coinfections, with the potential to transform understanding and treatment in this field.

The 2024-2025 Ag Conservation Research Grants program, offered by the Pennsylvania Department of Agriculture, aims to fund agricultural conservation research. This initiative aligns with the broader mission of promoting sustainable agricultural practices and protecting natural resources within the state. The funding, made available through the Clean Streams Fund Nutrient Management federal ARPA funds, underscores a strategic priority to improve water quality and address nutrient management challenges. The target beneficiaries of this grant program are researchers and institutions capable of conducting agricultural conservation research within Pennsylvania. The program's impact goals are to generate actionable data and recommendations that can inform and improve agricultural conservation efforts. This includes identifying sources of pollution, quantifying the effectiveness of various practices, and developing new methods for environmental protection. The program prioritizes several research topic areas, including identifying nuisance emissions in the mushroom industry and their mitigation, quantifying emissions from the mushroom industry, and measuring the impact of best practices. It also focuses on quantifying the impact of Manure Treatment Technologies (MTT) on water quality and providing recommendations for their improved utilization. Furthermore, the program seeks to quantify the impact of precision feeding on nutrient reductions and the climate benefits of best management practices installed through the Agriculture Conservation Assistance Program and Conservation Excellence Grant programs (ACAP & CEG). Expected outcomes include the development of new and improved conservation practices, a better understanding of the environmental impacts of agricultural operations, and evidence-based recommendations for policy and practice. Measurable results will stem from the quantification of emissions, nutrient reductions, and climate impacts, as well as the evaluation of technologies and practices. The department intends to make up to $1,500,000 available for grants under the program, with research to be conducted from July 1, 2024, to June 30, 2026, with the possibility of extension.

The Red Coats' Community Grants program is designed to fund smaller projects for nonprofit organizations in Northeast Florida, specifically in Baker, Clay, Duval, Nassau, and St. Johns counties. This program aligns with the Red Coats' mission, which involves a group of civic and corporate leaders overseeing THE PLAYERS volunteer efforts and a special grant program for local nonprofits. The grants are intended to support community needs within this five-county area, with individual awards of up to $15,000. The target beneficiaries of this program are citizens within the five-county area, served by eligible nonprofit organizations. The program aims to address specific community needs and provide services aligned with priority focus areas. These areas include youth services, education, character development, health, wellness and sports, and military support. The overarching impact goal is to foster broad community support and create positive change in these key sectors. The Red Coats prioritize funding organizations that demonstrate broad community support and actively address identified community needs. A crucial focus is on ensuring services are provided without discrimination, as protected by law. The program specifically excludes funding for individuals, private foundations, grant-making bodies, operational expenses (including salaries), travel or conference expenses, sponsorships with tangible staff benefits, political action committees, political causes or candidates, debt reduction, and gifts, honorariums, or gratuities. The expected outcomes of the grant program are to strengthen nonprofit organizations' capacity to deliver vital services in the priority areas. Measurable results would be tied to the specific projects funded, such as improved educational outcomes for youth, enhanced health and wellness initiatives, or increased support for military families. The foundation's strategic priorities are evident in its focus on local community development through targeted support in these key areas, leveraging the involvement of civic and corporate leaders to achieve its philanthropic goals.

The purpose of this initiative is to advance research that reduces firearm injury and disparities through the development and evaluation of firearm injury primary prevention interventions leveraging community healthcare settings. This funding opportunity solicits applications that focus on primary prevention of firearm injury leveraging community healthcare settings. Applications may propose intervention studies with a rigorous design including, but not limited to, policy implementation studies, natural experiments and other studies with a quasi-experimental design, as well as those meeting the NIH definition of a clinical trial. Aims may focus on efficacy, effectiveness, or hybrid effectiveness/implementation research. Health or behavioral outcomes for this funding opportunity should be appropriate to the aims and should include, but are not limited to, changes in behavior related to firearm injury prevention and firearm safety procedures, and implementation outcomes. Change in knowledge of firearm injury prevention measures may be a secondary outcome (e.g., as a mechanism of action) but should not be the focus of the project. Multi-level, multi-disciplinary interventions and outcomes are encouraged, including individual, interpersonal, organizational, and community levels. Individual level outcomes should be one of the outcome levels included. Rigorous methods that address potential sources of bias that are appropriate to the study design are expected. Intervention studies are expected to include a theory-informed examination of the mechanisms of intervention effects. Projects that are responsive to this funding opportunity include R01 studies of all size, from small, single-site, three-year projects such as to adapt an intervention to the community or to test efficacy of an intervention, to large multi-site trials to test effectiveness and implementation strategies. Applications that meet any of the non-responsiveness criteria will be considered non-responsive and will not be reviewed. Implementation studies should include an evaluation of the effectiveness of the intervention in the site or sites. Years requested and project budgets should reflect the scope of the project. A description of plans for community engagement, including clear justification of the planned approach, is required. Projects that focus on populations that experience health disparities are highly encouraged.

This grant provides funding to nonprofit organizations that train instructors to educate hazardous materials employees on safe handling and transportation practices.

The "CCRP Initiative: Countermeasures Against Chemical Threats (CounterACT) Therapeutics Discovery and Early-Stage Development" grant aims to fund the early-stage development of treatments to reduce the harmful health effects caused by exposure to toxic chemicals, which could be used in terrorist attacks or accidentally released from industrial sites, with the end goal of producing at least one well-characterized therapeutic candidate.

This program provides financial support to Minnesota-based businesses and organizations for replacing or retrofitting refrigeration systems with environmentally friendly options that reduce harmful greenhouse gas emissions.

Through this Funding Opportunity Announcement (FOA), the National Cancer Institute (NCI) invites applications for support of investigator-initiated studies addressing mechanisms by which bariatric surgery impacts cancer risk, and seeks to draw in talented scientists who study bariatric surgery to investigate its effects on cancer, rather than shorter-term outcomes such as weight loss and diabetes.Through this Funding Opportunity Announcement (FOA), the National Cancer Institute (NCI) invites applications for support of investigator-initiated studies addressing mechanisms by which bariatric surgery impacts cancer risk, and seeks to draw in talented scientists who study bariatric surgery to investigate its effects on cancer, rather than shorter-term outcomes such as weight loss and diabetes. Background Obesity: Obesity will soon surpass smoking tobacco as the number one cause of preventable death both in the United States and worldwide. Bariatric (metabolic) surgery is the most effective strategy to achieve significant initial and sustained weight loss among individuals who are morbidly obese. Bariatric surgery provides dramatic improvement in metabolic function, associated with a reduction in type 2 diabetes mellitus (T2DM) and cardiovascular (CV) risk. Bariatric surgery also appears to reduce the risk of certain obesity-related cancers, although which cancers are favorably impacted vary by study, and the mechanism(s) driving this risk reduction is mostly speculative. Bariatric surgery is performed in over 250,000 people in the U.S. annually, and the frequency is rising. Studies evaluating which bariatric surgery procedure(s) are most effective in cancer risk reduction could help bring to light new pathways to target for cancer prevention. Bariatric Surgery: Importantly, it is not yet clear from clinical and preclinical studies if the benefit from bariatric surgery arises from weight loss alone or if there is also a surgery-specific benefit. One mechanism for a possible surgery-specific effect is elevated bile acids (BA), both intestinal and circulating, after gastric bypass surgery such as Roux-en-Y gastric bypass (RYGB) that are proposed to be central to weight loss and other metabolic benefits. The interaction between BA and intestinal microbes is also an area of intense interest. Studies have identified important changes after bariatric surgery in the composition and function of the gut microbiome, which may mediate bariatric surgery effects. Fecal microbiota transplantation (FMT) from humans or mice that had undergone bariatric surgery to germ-free recipient mice showed decreased weight gain and decreased adiposity are both transmissible traits. In addition, FMT induced important host metabolic changes including decreased energy harvest from the diet, increased resting energy expenditure, and increased lipid utilization. The data suggest a causal link between gut microbiota and the metabolic and weight loss effects of bariatric surgery. If validated, the findings will provide insight into the mechanisms driving the benefit of bariatric surgery on cancer risk and would be useful to further scientific understanding and patient care. Animal Models: Several diets or genetically induced animal models of obesity have consistently demonstrated the benefits of weight loss on cancer risk, and these obesity-induced tumor models may be adaptable to bariatric surgery studies, such as the Kras model of pancreatic cancer. Animal models have been developed to study the effects of bariatric surgery. Rodent animal models are most often used due to feasibility (low cost, ease of housing) and have been used extensively to study the mechanism(s) of bariatric surgery responsible for the reduction or elimination of T2DM and CV risk. However, very little has been reported on bariatric surgery and cancer risk despite the fact that both rat and murine models of mammary and other cancers develop in 6 months or less, making it feasible to assess mechanistic changes that influence cancer risk. Bariatric Surgery and Cancer Risk: Obese patients undergo bariatric surgery for a variety of reasons, including weight loss and improvement in metabolic dysfunction. Physician advice regarding the potential benefit of bariatric surgery and cancer risk reduction can currently only be given in generalities based on large-scale studies and not targeted to the individual. Many but not all bariatric surgery investigations document an overall cancer risk reduction among women but not men. Some but not all bariatric surgery studies have found that both women and men undergoing bariatric surgery have an increased risk of colorectal cancer (CRC). Older studies which assessed bariatric surgery and cancer risk may not be useful to guide targeted advice to patients, as one of the most common procedures performed in the past, gastric banding, is only performed in 1% of bariatric surgery procedures today. The two most common bariatric surgery procedures currently performed are sleeve gastrectomy and RYGB. As such, planned animal and/or human studies should focus on the mechanistic effects of the two procedures that are currently in common use. Human biospecimens and/or data may be available from cohorts to enhance the studies proposed including the Longitudinal Assessment of Bariatric Surgery (LABS), Adolescent Bariatrics: Assessing Health Benefits & Risks (Teen-LABS), and NCI Cohort Consortium Members. Applications that include collaborators from fields outside of cancer research will be given special programmatic consideration. Responsive applications may investigate animal models, human studies, or a combination of both. General Area of Research and Scope of Work for this FOA General Area of Research Examples of relevant areas of research include but are not limited to: Do alterations in cancer risk biomarkers occur before weight loss? If so, in what organ, tissue, or cell type do they originate? Is maximum weight loss or long-term weight loss more important for cancer risk reduction? If so, how do the two differ at a cellular and/or biochemical level? What mechanism(s) explain the evidence that bariatric surgery is more beneficial in cancer risk reduction in women than men? Does bariatric surgery increase or decrease the risk of CRC, and if so, what are the mechanism(s)? Which cancers are decreased in incidence by bariatric surgery, and what are the mechanism(s) that explain the effect? Are any cancers increased in incidence by bariatric surgery? If so, through what mechanism(s)? Does the specific bariatric surgery procedure have an impact on cancer risk? If so, what are the mechanism(s) driving the difference in impact? Does racial or ethnic background influence the impact of bariatric surgery on cancer risk, and if so, what are the mechanism(s) involved? How does bariatric surgery affect the penetrance of high-risk genetic predisposition to cancer? Scope of Work and Additional Guidance It is anticipated that studies will evaluate bariatric surgery animal models where a significant proportion of the animals develop cancer. Similarly, human studies involving individuals who will or have undergone bariatric surgery are also encouraged, so long as within the cohort to be studied the number of enrolled subjects who develop cancer is adequate to for a statistically powered endpoint linking cancer (and not a biomarker of cancer) to a molecular mechanism as the driver of cancer. When appropriate and feasible, the investigators may want to evaluate mechanisms influenced by bariatric surgery in animal models of cancer and evaluate potential changes that might correlate with humans due to bariatric surgery. We define mechanism as a biologic endpoint based on analyzed samples from bariatric surgery animal models or from subjects who have or are planned to undergo bariatric surgery. This FOA does not support studies where an epidemiologic endpoint is the primary aim of the project. The mechanism(s) to be studied should evaluate samples collected from animals or humans who have undergone bariatric surgery who did or did not develop cancer. If both animals and humans are studied, the mechanisms chosen should be based on a cancer endpoint. Applications Not Responsive to This FOA The following types of activities remain outside the scope of this FOA, and applications proposing them are non-responsive to this FOA and will not be reviewed. This FOA is not intended for epidemiologic studies, where the primary endpoint is the assessment of cancer in a cohort of animals or humans, which has undergone bariatric surgery and mechanistic studies evaluating bodily fluid or tissue samples are nonexistent or of secondary endpoints. Application that focuses entirely on in vitro investigations. Epidemiologic investigations as the primary focus of the application. Animal or human studies that do not evaluate tissue and/or bodily fluid samples collected from participants who have undergone bariatric surgery, some of which developed cancer after surgery. Application, which includes a clinical trial that does not have a bariatric surgeon as a key investigator on the team. NOTE: Applicants to this FOA are strongly encouraged to contact NCI staff as soon as possible in the development of the application (preferably no later than 12 weeks prior to the application due date) to discuss the details of their proposed clinical trial, so that NCI staff can help the applicant understand whether the proposed clinical trial is within the goals and mission of the NCI and is appropriate for this FOA.

This funding opportunity provides financial support for research projects that aim to improve the adoption and sustainability of effective health interventions, particularly in underrepresented communities, by addressing barriers and promoting equitable health outcomes.

This funding opportunity provides financial support to local nonprofit organizations in Murfreesboro to deliver essential services and affordable housing solutions for low- and moderate-income residents.