Grants for City or township governments - Health

ERF was established to increase collaboration between Cal ICH, Local Jurisdictions, and Continuums of Care (CoCs) for the following purposes: • Assist Local Jurisdictions in ensuring the safety and wellness of people experiencing homelessness in encampments.• Provide grants to Local Jurisdictions and CoCs to resolve critical encampment concerns and transition individuals into safe and stable housing.• Encourage a data-informed, coordinated approach to address encampment concerns.

This funding opportunity supports researchers exploring the ethical, legal, and social issues related to human genetic and genomic research, particularly as these technologies become more integrated into healthcare and society.

The purpose of this Funding Opportunity Announcement (FOA) is to correlate immune system development patterns between two or more age groups - neonates, infants, and children and adolescents and further understand the impact of infectious diseases, microbiome and environmental factors on the ontogeny and development of the pediatric immune system, from birth, transitioning into adolescence and adulthood with the focus of impact during pregnancy and post-natal period.Purpose The purpose of this Funding Opportunity Announcement (FOA) is to correlate immune system in general and development patterns in particular, between two or more age groups - neonates, infants, and children and adolescents and further understand the impact of infectious diseases, microbiome and environmental factors on the ontogeny and development of the pediatric immune system, from birth, transitioning into adolescence and adulthood with the focus of impact during pregnancy and post-natal period. Background Worldwide, mortality in children under the age of 5 is predominantly due to infectious diseases and immune modulations associated with these infections. Pediatric immune system is remarkably different from adult immune system and also forms the basis for overall wellbeing and providing an adequate disease encountering status to adulthood. A protected and systematically trained pediatric immune system results in a robust and efficient adult immune system. Moreover, immune system in children responds strongly, rapidly and robustly in comparison to adult immune system to immunization, diet and environmental factors. Knowledge of development of the pediatric immune system in response to exposure to childhood infections and vaccinations, microbiome and the environmental factors can help chart pathways that provide strategies to prevent and treat infectious diseases more efficiently. These variations between pediatric and adult immune systems offer insight into better understanding strategies for developing immune-therapeutics and vaccines against infections. The research focus in the current announcement is multi-disciplinary. The focus however is in the areas of immune ontogeny and development, the mechanisms of infant and neonatal immunity or relationship between ontogeny of immunosuppression, susceptibility to infection during infancy or studies on effect of early infections or vaccinations that train the immune system. It is expected to diversify areas in existing research and draw comparisons between age groups or specific organ system development (for example, projects of interest might investigate immune cell ontogeny in lung alveoli from infancy to adult hood or immune alterations due to exposure to a specific immunogen (like measles or BCG vaccine) at infancy vs adolescence and the chronic effect of air pollution). More specifically, the aim here is to elucidate immune system development patterns in infants, children and adolescents focusing on both the innate immunity and the development of diverse antibodies or T cell maturation, with relevance to chronic infections (not limited to HIV, CMV, TB and the current SARS-CoV2 pandemic as well). Further, the intention is to expand the science to include additional internal factors like microbial metabolites and/or external factors like the environment that modulate the developing immune system so that a research program that is multi-disciplinary can be developed to address the interaction between host and pathogen. Research Scope The over-arching scope of this FOA is: to correlate immune system in general and development patterns in particular, between two or more age groups - neonates, infants, and children and adolescents to understand the evolution or immune ontogeny in human immune system development focusing on either or both, innate and adaptive immune systems with additional focus on internal factors like the microbiome and/or external factors like the environment. Further, the scope can be covered under these following topics and is not limited to: Study in young children vs adolescents vs adults, development of immunity and variations in immune system in physiology and in response to infectious diseases focusing on MTCT diseases (HIV, CMV, TB, Syphilis, SARS-CoV2 etc.), not limited to, broadly neutralizing antibodies (bNAbs), development of mucosal antibodies, germinal center formation and maturation; correlate with T cell development and identification of immunogens that activate T cells without enhancing infection. Characterize the impact of age, environmental factors, microbial metabolites and microbiome composition in relation to the immune responses against acute or chronic infectious diseases not limited to HIV, TB, CMV, SARS-CoV2 etc., and their contribution towards the development of a robust immune system development using novel technologies (RNA seq, imaging of immunogens and cellular interactions, single cell imaging). Understand cellular and soluble immune system components and the developmental pathways, including the microbiome, that regulate these components in specific age-groups. For example, developing immune profiles of HIV exposed un-infected (HEU) infants in comparison with the immune profile of an adolescent living with HIV and how these immune alterations prepare the immune system to encounter future infections. Study the contribution of increased exposure to environmental factors, pathogens, extensive or scheduled immunization early in life on enhanced cross-talk between innate and adaptive immune systems; specific inflammatory responses generated by innate immune factors and their downstream effect on cellular immune development. Delineate the role of human microbiome in health and disease and the environmental factors to observe correlation of immune responses against acute and chronic infections and focus on transfer of microbes and immune factors from human milk to infants. For example, assess alterations in immune profiles of known oral microbial clusters in CMV infected child vs immune profiles in an adolescent. Understand the impact of variations of microbiome in specific organ systems (gut vs oral vs vaginal microbiomes) in age defined profiles and their effect on immune ontogeny with emphasis on Virome . Influence of maternal microbiome on the effect of microbial composition and development of immunity in the offspring; detailed studies exploring placental microbiome and correlation with maternal oral microbial microbiome are encouraged. Projects that will be considered non-responsive for this FOA include, but are not limited to: Applications proposing vaccine advocacy. Applications proposing to focus exclusively on effects of microbiome and not studying the relevance of these effects on immune system development. Applications proposing to focus exclusively on epigenomic approaches. Applications focusing on immunization strategies in infants for altering early immune responses.

This grant provides funding for research projects aimed at improving the diagnosis and treatment of health conditions related to the September 11, 2001, terrorist attacks, specifically for individuals who were exposed in New York City and surrounding areas.

This funding opportunity provides financial support to states and organizations for developing a coordinated care model that improves health services for children with serious, long-term medical conditions.

This grant provides funding to strengthen the management and evaluation of human resources in Malawi's national HIV and TB programs, focusing on hiring skilled personnel to support epidemic control efforts.

This funding opportunity supports multidisciplinary research teams in the U.S. working on complex biomedical questions, with a focus on advancing foundational biological processes and addressing critical health issues.

The purpose of the USAID Usalama ya Afya Duniani activity is to support the strengthening of Tanzanias capacities to develop, validate, and implement interventions to prevent, detect, and respond to EID threats in Tanzania using a One Health approach.The United States Agency for International Development (USAID) Mission in Dar es Salaam, Tanzania is publishing this Request for Information (RFI) to obtain information and inputs from all capable and interested entities for the anticipated USAID Usalama wa Afya Duniani activity. This activity is designed to identify and implement proven, collaborative, and evidence-based Global Health Security approaches in Tanzania, in support of strengthening the country’s capabilities to prevent, detect and respond to emerging infectious disease outbreaks.

Dear Interested Applicants:This Annual Program Statement (APS) publicizes in accordance with ADS 303.3.5.2(b) as the intention of the United States Government (USG), as represented by the United States Agency for International Development (USAID), Indonesia Mission, to fund one or multiple awards to improve the capacity of the National Tuberculosis Program, local partners, and communities to effectively detect, diagnose, and treat people affected by tuberculosis and provide preventive services to all people in need, while building a sustainable and resilient health system in Indonesia.This document is an umbrella APS that is not calling for any submission and will not solicit any concept papers nor applications. Prospective applicants will be provided a fair opportunity to develop and submit competitive applications to USAID for potential funding via APS Addendums under this APS. USAID Indonesia intends to make several assistance awards with US and local NGOs to assist the Government of Indonesia (GOI) in accelerating achievement toward its 2030 TB elimination.Following this APS, USAID will issue APS Addendum(s) with more detailed information for applicants to submit their applications. USAID Indonesia may utilize co-creation with prospective applicants during various stages of APS Addendum procurements and applicants may be invited to participate in virtual or in-person events. If/when there is any change related to this APS, the mission will amend this APS accordingly.Issuance of this APS does not commit USAID to make any awards nor to pay for the costs incurred in the preparation and submission of an application. USAID also reserves the right to reject any application received in response to the APS Addendum(s). USAID reserves the right not to conduct a co-creation and request Full Applications from successful applicants at the concept paper stage, or to conduct co-creation at a later stage of the process. The actual number of awards under this APS is subject to the availability of funds and the viability of applications received. USAID also reserves the right to award multiple awards or no awards at all through this APS.This APS and the APS Addendum will be posted on www.sam.gov and www.grants.gov. It is the responsibility of the Applicant to regularly check both websites to ensure they have the latest information pertaining to this APS and to ensure that the APS has been received from the internet in its entirety. USAID bears no responsibility for any data errors resulting from transmission or conversion process. If you have difficulty registering on www.grants.gov or accessing the APS document, please contact the Grants.gov Helpdesk at 1-800-518-4726 or via email at support@grants.gov for technical assistance.Thank you for your interest in USAID programs.

This grant provides funding to early-stage researchers exploring innovative chemical and pharmacological approaches to understanding and treating substance use disorders.

This funding opportunity provides financial support to local governments, tribal entities, and certain non-profits in Oklahoma for various solid waste management initiatives, including cleanup efforts and equipment purchases, to promote environmental sustainability.

The STRIPE program grant is designed to fund pre-clinical research that explores how radiopharmaceutical therapy affects cancer cells and their environment, with the aim of developing new targeting strategies and informing the design of future RPT-based clinical trials.

This funding opportunity supports innovative interventions to improve the health and quality of life for people living with HIV, particularly those from racial and ethnic minority populations and low-income backgrounds, by addressing related health issues and promoting successful aging.

This funding opportunity supports innovative research projects aimed at improving mental health services and addressing disparities in access and quality, particularly for underserved populations.

The Duplin County Community Foundation (DCCF) Grant Program is currently accepting applications to support qualified charitable organizations serving the local community of Duplin County, North Carolina. This grant program is aligned with the DCCF's mission to address a broad range of local needs. The grant-making fund supports various purposes, including human services, education, youth development, health, food/nutrition, and arts. The foundation's strategic priority is to foster a responsive grant-making approach that addresses the diverse needs within the community, ensuring that funds are directed where they can have the most significant impact. The target beneficiaries of this grant program are organizations that serve the community-at-large within Duplin County. This includes 501(c)(3) public charity nonprofit organizations, organizations with a fiscal agent who is a 501(c)(3) public charity nonprofit, local governments (including public schools), and fire and rescue departments. Religious entities may also apply for funding to support social outreach and charitable service programs benefiting the community, but not for general operating support. The impact goal is to strengthen the local community by supporting essential services and programs that improve the quality of life for its residents. The foundation aims to create a ripple effect of positive change through its investments. The program prioritizes initiatives that meet local needs in a wide array of areas. This broad focus allows for flexibility in addressing emerging challenges and opportunities within Duplin County. The expected outcomes include enhanced community services, improved educational opportunities, healthier residents, and greater access to nutritious food and artistic programs. Measurable results would be evidenced by the number of individuals served by grant-funded programs, improvements in specific indicators related to health or education, and the overall positive impact on the well-being of Duplin County residents. The Duplin County Community Foundation's theory of change is rooted in the belief that by providing financial support to well-aligned and impactful local organizations, the foundation can empower these entities to deliver vital services and programs. This, in turn, leads to a stronger, more resilient, and vibrant community. The foundation emphasizes inclusivity, requiring organizations to offer programs and services without discrimination based on age, race, national origin, ethnicity, gender, physical ability, sexual orientation, political affiliation, or religious belief, ensuring equitable access to resources and benefits for all residents. The typical grant range from the community grantmaking fund is $500 to $1,000.

The Indiana Office of Community & Rural Affairs (OCRA) is seeking applications for its Building Socially Connected Communities Program, a grant initiative designed to address concerning public health statistics in Indiana through a community and economic development lens. This program aligns with the foundation's mission to enhance community resilience and foster economic growth across the state. By investing in initiatives that build social connections, strengthen community bonds, and enhance the overall quality of life for Hoosiers, OCRA aims to strategically counter social isolation and loneliness, which diminish social capital and impact individual and community well-being. The program targets all counties in Indiana and aims to benefit individuals experiencing social isolation and loneliness, local businesses affected by decreased community engagement, and communities striving for greater economic vibrancy and social cohesion. The impact goals are to improve individual health outcomes, enhance community well-being and social capital, foster community engagement, support local businesses, and contribute to the overall economic health of Indiana’s communities. The program's priorities and focus areas include Community Infrastructure Enhancement (e.g., community centers, meeting spaces), Social Clubs & Interest Groups tailored to older adults, Community Well-Being Programs (e.g., mental health awareness, loneliness stigma reduction, accessible resources), Local Business Support (e.g., creating inviting spaces for social interactions), Transportation Accessibility in rural areas, and Intergenerational Initiatives. These focus areas reflect the foundation's strategic priority to create strong, connected communities. Expected outcomes and measurable results include increased social connections, stronger community bonds, enhanced quality of life, greater community engagement, improved economic vibrancy through local business support, and increased access to community events and essential services. The foundation's theory of change posits that by strategically investing in these areas, communities will experience a positive shift in social fabric, economic health, and overall well-being, contributing to Indiana’s statewide development goals. Funding information includes a total of $200,000 available. Applicants can apply for either Quick Action projects (maximum $5,000, minimum $1,000, 1:1 match with 30% in-kind) or Large Impact projects (maximum $50,000, minimum $5,001, 1:1 cash match). Eligible applicants are local government, non-profit organizations, and community groups. Ineligible activities range from plants and Wi-Fi to one-time use products, permanent public restrooms, taxes, food/drink, gaming, illegal/political/unsanctioned activities, demolition, salaries, administration fees, and pre-award expenses.

This funding opportunity provides financial support for researchers and institutions to discover and develop new treatments for serious fungal infections that are difficult to treat due to resistance and safety issues.

This funding opportunity provides financial support to schools and organizations to promote safe walking, biking, and rolling to school, fostering healthier transportation habits and improving community infrastructure for students in grades K-12.

This funding opportunity supports research projects that aim to improve the adoption and sustainability of effective health interventions, particularly in underserved communities, while also addressing the reduction of ineffective practices.

The "BRAIN Initiative: Research Resource Grants for Technology Integration and Dissemination" grant aims to support the distribution, integration, and minor improvement of existing neuroscience research tools and technologies, as well as user training, to help achieve the goals outlined in the "BRAIN 2025: A Scientific Vision" report.