Grants for Independent school districts - Health

This funding opportunity supports small-scale research projects that analyze existing genomic data to advance understanding of dental, oral, and craniofacial health, particularly focusing on health disparities and biological pathways for intervention.

The "Early- and Late-Stage Clinical Trials for the Spectrum of Alzheimer's Disease/Alzheimer's Disease-Related Dementias and Age-Related Cognitive Decline" grant is a $20 million funding opportunity from the National Institutes of Health, aimed at supporting innovative clinical trials that develop and test pharmacological and non-pharmacological interventions for Alzheimer's disease and age-related cognitive decline over a five-year period.

This grant provides funding for researchers to develop a vaccine against Kaposi sarcoma herpesvirus (KSHV), aiming to prevent infection and treat related diseases in affected populations.

This funding opportunity provides financial support for researchers to utilize existing data to advance studies on substance use and addiction, encouraging innovative analysis without the need for new data collection.

This funding opportunity provides financial support to higher education institutions and nonprofits to establish or renew research centers focused on advancing studies related to Alzheimer's disease and related dementias, promoting collaboration, innovation, and diversity in research efforts.

This funding opportunity provides financial support to researchers with active NIH grants to quickly adapt their projects to address urgent public health crises that have emerged unexpectedly.

This funding opportunity supports short-term research projects that explore the ethical challenges arising from advancements in neurotechnology and brain science, encouraging collaboration between ethicists and neuroscientists.

The "Clinical Trial Readiness for Rare Diseases, Disorders, and Syndromes" grant aims to fund research projects that prepare for clinical trials in rare diseases by developing effective strategies for testing potential treatments or diagnostics, improving success rates with robust biomarkers and assessment measures, or by understanding the progression of a rare disease to design future clinical trials.

This funding opportunity provides financial support for research projects aimed at overcoming barriers to HIV prevention for marginalized individuals who use substances, focusing on improving access to and retention in PrEP care.

This funding opportunity supports U.S. research institutions in training and developing Ph.D. students from underrepresented groups in biomedical research to address national health-related challenges.

The purpose of this Funding Opportunity Announcement (FOA) is to support innovative multidisciplinary and multi-level research designed to develop and/or test interventions to optimize care of persons with Type 2 diabetes from populations with health/health care disparities concordant with evidence-based guidelines. NIH-designated health disparity populations include racial and ethnic minorities (Blacks/African Americans, Hispanics/Latinos, American Indians/Alaska Natives, Asians, Native Hawaiians and other Pacific Islanders), sexual and gender minorities, socioeconomically disadvantaged populations, and underserved rural populations. Proposed projects would be expected to develop and/or test patient-centered strategies, which in addition to optimal glycemic control, would aim at completing other recommended guidelines (e.g., annual eye/foot and urine albumin exam, optimal blood pressure control, intake of ACEIs or ARBs/statin/aspirin and influenza/pneumonia vaccines).

This funding opportunity supports U.S. institutions in developing educational programs for psychiatry residents to enhance their research skills and encourage careers in mental health research.

This funding opportunity invites research institutions to join a collaborative effort aimed at advancing stillbirth research, particularly focusing on reducing stillbirth rates in vulnerable populations through innovative scientific approaches.

This funding opportunity provides financial support for the development of innovative informatics tools that will help researchers effectively utilize the human pangenome reference to advance genomics research across various applications.

This grant provides financial support to tax-exempt organizations in Boone County, Iowa, for projects that enhance community well-being in areas such as arts, education, health, and environmental protection.

This funding opportunity provides financial support to various organizations for developing and implementing public health strategies aimed at improving brain health and addressing the challenges of Alzheimer’s disease and related dementias, particularly for underserved populations.

The Joe DeMott Port Allegany Community Development Fund, administered by the McKean County Community Foundation, is currently accepting applications. This grant program aims to support a wide array of projects, aligning with the Foundation's broader mission of fostering community well-being and development. The fund's focus areas, including arts, community development, education, environment, and health and social services, reflect a comprehensive approach to addressing the diverse needs within the Port Allegany School District. The primary beneficiaries of this fund are organizations operating within the Port Allegany School District, specifically 501c3 organizations, schools, municipalities, or religious organizations that serve the public. The impact goal is to enhance the quality of life and promote growth in these key areas. By supporting local initiatives, the fund seeks to empower community groups to implement projects that create positive, tangible changes for residents. The program prioritizes projects that fall under the aforementioned categories: arts, community development, education, environment, or health and social services. This broad scope allows for a variety of innovative and impactful projects to be considered. The strategic priority of the McKean County Community Foundation, as evidenced by this fund, is to invest in local communities to cultivate sustainable development and address critical needs across multiple sectors. While specific expected outcomes and measurable results are not explicitly detailed in the provided information, the nature of the supported areas implies a desire for improved community infrastructure, enhanced educational opportunities, increased access to arts and cultural experiences, a healthier environment, and more robust social support systems. The theory of change behind this fund is likely that by providing financial resources to local organizations, they can effectively implement projects that lead to a stronger, more vibrant, and more resilient Port Allegany community. The maximum grant amount of $1400 suggests an emphasis on supporting numerous smaller-scale, impactful initiatives.

To advance the field of patient-centered clinical decision support through research that tests tools and resources in real-world settings. The mission of the Agency for Healthcare Research and Quality (AHRQ) is to produce evidence to make healthcare safer, higher quality, and more accessible, equitable, and affordable, and to work within the U.S. Department of Health and Human Services and with other partners to make sure the evidence is understood and used. The purpose of this Notice of Funding Opportunity (NOFO) is to conduct research on patient-centered clinical decision support (PC CDS), a nascent area within the larger field of CDS. Through the AHRQ-funded Patient Centered Outcomes Research (PCOR) CDS Initiative and the CDS Innovation Collaborative specifically, PC CDS resources are now publicly available for interested researchers to further build upon, develop, and test, in real-world settings. Innovative research is needed to understand how to make traditional, clinician-facing CDS more patient-centered, while also engaging patients, families, and caregivers in a co-design process to design and implement these tools. BACKGROUND Clinical decision support refers to digital tools that are used to help inform patient care. Patient-centered clinical decision support (PC CDS), in contrast to traditional clinician-facing CDS, is CDS that focuses on the patient, or their caregiver, and facilitates their active involvement in healthcare decision-making with their clinicians. PC CDS uses information from patient-centered outcomes research findings and/or patient-specific information and has the potential to be transformative by enabling higher-quality care delivery and improved outcomes. PC CDS can also support shared decision making (SDM), which AHRQ defines as a collaborative process in which patients and clinicians work together to make healthcare decisions informed by evidence, the care team's knowledge and experience, and the patient's values, goals, preferences, and circumstances. PC CDS can also support shared care planning enabling patients, caregivers, and clinicians to work together to tailor a clinical plan to align with a given patients priorities and goals. PC CDS is a developing field and has the potential to increase the quality and experience of patient care. AHRQ’s CDS Initiative is supported by the Patient Centered Outcomes Research Trust Fund (PCOR TF) and is guided by AHRQ’s PCOR TF strategic framework (https://www.ahrq.gov/pcor/strategic-framework/index.html). Since 2016, AHRQ’s PCOR CDS Initiative has been building tools, concepts, frameworks, and conducting pilot projects. Much of AHRQ’s recent effort has focused on patient-centered CDS, and several past projects have generated resources that could be highly useful to the developing PC CDS field. Examples of these projects include AHRQ’s PC CDS Learning Network and CDS Connect, as well as a project that assessed the current state and future directions with PC CDS. Additional information for CDS projects is available on the PCOR CDS Initiative webpage. AHRQ’s most recent PC CDS project, the CDS Innovation Collaborative, or CDSiC, is a multi-component stakeholder-driven initiative that produced a rich set of resources and tested concepts around different aspects of PC CDS. As part of the CDSiC, four workgroups were formed, each around a specific area of PC CDS, with the charge to create products (e.g., frameworks, guides, checklists) that could be used in the clinical field to establish or measure use of PC CDS. These products could address clinical workflows or the development of CDS technologies, among other areas related to PC CDS. During the first two years of the CDSiC, these workgroups created numerous products that addressed PC CDS in different areas. These areas included CDS outcomes, trust and patient-centeredness, and scaling and dissemination. One workgroup also focused on the existing standards and regulatory frameworks that could impact the future uptake and use of PC CDS. Applicants can examine, using these products and tools, how PC CDS can support shared decision making and care planning among individuals with complex needs including older adults, people living with multiple chronic conditions, frailty, disabilities, and/or socioeconomic disadvantage and how this may foster the delivery of person-centered care. They may also study strategies to scale and spread effective tools including use in lower resourced and safety net instituions. Applicants responding to this NOFO must propose to use the resources developed by AHRQ's PCOR CDS Initiative, or any of the many products developed by the ongoing CDSiC, to further explore their usefulness, impact, and practical application in real-world settings. For example, CDSiC products that could be used may include the Taxonomy of Patient Preferences, Integration of Patient-Centered CDS into Shared Decision Making, Approaches to Measuring Patient-Centered CDS Workflow and Lifeflow Impacts, or the PC CDS Performance Measurement Inventory User Guide. Links to and descriptions of the products are available on the CDSiC Stakeholder Center webpage (https://cdsic.ahrq.gov/cdsic/cdsic-stakeholder-community-outreach-center ) The CDSiC's Innovation Center (https://cdsic.ahrq.gov/cdsic/innovation-center) developed a comprehensive report around measurement of PC CDS and created two pilot dashboards that can help clinicians understand and use Patient Generated Health Data. Additional information on other PCOR CDS projects is available at https://cds.ahrq.gov/about. Examples of Highly Responsive Projects include: A community hospital with a large priority population, selects from the CDSiC portfolio of projects generated by the Trust and Patient-Centeredness workgroup. The recipient selects the source credibility product from the Trust and Patient Centeredness workgroup and conducts a study to understand how their population perceives the information they receive from within their existing electronic health record (EHR) system. Patients provide input, and the approach is assessed against existing CDS tools, as well as the definition of PC CDS as defined by the CDSiC, to assess their level of patient-centeredness. A small startup company is developing applications (apps) to help patients improve their healthcare. The startup leverages two products from the CDSiC standards and regulatory frameworks workgroup: Advancing Standardized Representations for Patient Preferences to Support Patient-Centered Clinical Decision Support and an Environmental Scan that reveals opportunities to evolve standards and regulatory frameworks to advance PC CDS. The company works with a patient advocacy organization to co-design the patient-facing PC CDS app, uses standards to leverage existing patient generated health data (PGHD), and incorporates a final assessment as to the level of patient-centeredness of their technology. A primary care physician group is working to reduce clinician burnout with the goal of improving patient outcomes. The group looks at the CDSiC’s Taxonomy of Patient Preferences and assesses how they can incorporate these concepts into restructured workflows. The group then also uses CDSiC’s product called Approaches to Patient-Centered CDS Workflow and Lifeflow Impact, which provides a framework to help identify the optimal point for a patient-centered CDS tool’s deployment in a patient’s lifeflow. Their study will also assess how increased patient-centeredness in their CDS tools do not inadvertently have a negative impact on clinician workflows or experience. All projects are encouraged to: Incorporate Clinical Quality Language (CQL) and other HL7 standards into their project design, if appropriate for developing, integrating, (or modifying) their CDS with their EHR system or other health information technology (Health IT) components to become more patient-centered. OBJECTIVES AND SCOPE This NOFO aims to support innovative collaborative research to understand how clinical decision support tools in real-world settings can be improved to become more patient centered. Recipients will become part of an existing community of researchers who have an interest in PC CDS including AHRQ, the CDSiC, and other researchers. Interested applicants may include health information technology experts, patient advocates and representatives, clinicians, electronic health record developers, policymakers, payors, as well as leaders from research and academic medical institutions. All projects must: Utilize one or more of the products from the CDSiC or the PCOR CDS Initiative, which are available on the project website: cdsic.ahrq.gov, or another resource available from the PCOR CDS Initiative (cds.ahrq.gov), which includes the PC CDS Learning Network, CDS Connect, or AHRQ's Evaluation project that assessed the current state and future directions with PC CDS; If CDSiC products are used specifically, applicants must identify if any other frameworks are being used to evaluate the performance of their PC CDS (e.g., RE-AIM or other); Apply the definition of patient-centered CDS (available here: https://cdsic.ahrq.gov/cdsic/patient-centered-clinical-cds-infographic) and describe the degree to which each of the 4 elements are incorporated into the patient-centered CDS tool: knowledge, patient data, delivery, and use. Apply an equity lens, consistent with AHRQ's PCOR Strategic Framework. Apply at least 1 of the 4 priorities from AHRQ's PCOR Strategic Framework. Include meaningful and substantial participation from patients and/or patient representatives in the co-design, implementation, and evaluation of their research, to also be reflected in the proposed budget. Fully describe their research ecosystem. If developing or extending a digital tool, be mobile friendly to be more accessible to a broader population (for example, a patient-facing portal, website, etc.). If the research or tool will be incorporated into an EHR system, the facility must have a mature, functioning EHR system (e.g., the facility is not planning any significant system upgrade or migration). Otherwise, an alternative means to test and evaluate the selected CDS product can be described. If the research strategy intends to modify an existing clinical workflow that is currently clinician-focused, to become a patient-centric or patient-facing approach, then the strategy must include an evaluation component to characterize the performance of the PC CDS tool versus the previous clinician-facing workflow. If the proposed project plans to promote implementation of SDM, it should align with AHRQ’s definition of SDM (available here: https://www.ahrq.gov/sdm/about/index.html) and include at least one validated measure of SDM in its evaluation.

This funding opportunity supports high-risk, multi-center observational studies aimed at improving understanding and treatment of diabetes, digestive diseases, and kidney-related conditions, targeting a wide range of eligible public and private institutions.

This grant, under the authority of Public Act 53 of 2022, is part of the American Rescue Plan Act of 2021, designated to enhance public outdoor recreation facilities through the development, renovation, or redevelopment of local parks and trails. The funding aims to modernize these facilities and promote public recreation, equity, tourism, and economic recovery from the impacts of the COVID-19 pandemic. Eligible subrecipients must maintain an active SAM registration and use the funds in accordance with the established terms, including meeting deadlines for expense obligations and expenditures by specific dates in 2024 and 2026 respectively.