Grants for Nonprofits - Health

The Boston Athletic Association (B.A.A.) Gives Back Grant Program, now in its second round for 2024, is an initiative by the Boston Athletic Association to support nonprofit organizations in Massachusetts. Launched in 2023, the program has already benefited 32 organizations, distributing $400,000 to date. This grant program is a direct reflection of the B.A.A.'s core mission, which is to promote a healthy lifestyle through sports, particularly running, with the overarching goal of building healthy communities. The program aligns with the B.A.A.'s strategic priorities by investing in local nonprofits that share this commitment to community well-being through athletic engagement. The primary beneficiaries of this grant program are nonprofit organizations that are registered 501(c)(3)s or public agencies, are non-political, and are located in and serve residents of Massachusetts. These organizations must demonstrate a program that directly advances the B.A.A.'s mission of fostering healthy lifestyles through sports, especially running. The impact goal is to strengthen communities statewide by supporting initiatives that encourage physical activity and promote overall health. The program's priorities and focuses are centered on supporting organizations that use sports, particularly running, as a vehicle for community health and development. The grants range from $5,000 to $15,000 in this funding round, indicating a focus on providing accessible funding to a broad range of qualifying organizations. The B.A.A. emphasizes that organizations are eligible to receive funding once per calendar year, suggesting a commitment to sustained support for its partners. The expected outcomes of the B.A.A. Gives Back Grant Program include an increase in community engagement in healthy lifestyle activities, improved access to sports and running programs for Massachusetts residents, and the empowerment of local nonprofits to expand their reach and impact. While specific measurable results are not detailed in this description, the historical data of 32 organizations benefiting and $400,000 awarded statewide since inception serve as initial indicators of the program's reach and the B.A.A.'s theory of change—that by investing in local sports and running initiatives, they can foster healthier, more vibrant communities across the state.

The purpose of this Notice of Funding Opportunity (NOFO) is to support milestone-driven projects focused on developing and utilizing novel predictive models, assays, tools, and/or platforms based on penetration and efflux of small molecules to facilitate therapeutic discovery for select Gram-negative bacterial pathogens: carbapenem-resistant Acinetobacter, carbapenem-resistant Enterobacteriaceae (CRE), and multidrug-resistant Pseudomonas aeruginosa. A number of Gram-negative bacterial pathogens are associated with the alarming increase in rates of drug resistance in healthcare and community settings. This group includes carbapenem-resistant Acinetobacter , carbapenem-resistant Enterobacterales (CRE), and MDR Pseudomonas aeruginosa that have been designated as “urgent” or “serious” threats in a recent report by the Centers for Disease Control and Prevention (CDC). A significant threat arises from the lack of effective therapeutic options available to treat some of these infections and is exacerbated by the scarcity of novel compounds effective against antimicrobial resistant (AR) and multidrug-resistant (MDR) Gram-negative bacteria in the discovery and development pipeline. In recent years, several public forums (including NIAID-sponsored workshops) identified the lack of understanding of the principles that govern compound penetration into, and efflux out of, Gram-negative bacteria as a key bottleneck for the rational discovery of novel lead therapeutic compounds. The paucity of suitable assays/tools/models to inform structure-activity relationships and guide optimization of whole cell penetration (and efflux avoidance) is reflected in the failure of medicinal chemistry efforts to advance novel chemical classes of compounds with Gram-negative activity. As more Gram-negative bacteria become resistant to antimicrobials and therapeutic options become limited or nonexistent, it becomes imperative to understand and rationalize the principles that allow molecules to penetrate Gram-negative bacteria, while avoiding efflux and overt toxicity toward eukaryotic cells. Therefore, developing new assays, tools, and models is paramount for overcoming this key bottleneck and facilitating the development of novel compounds targeting Gram-negative pathogens. Research Objectives and Scope The objective of this NOFO is to support milestone-driven projects focused on developing and utilizing novel predictive models, assays, tools, and/or platforms aimed at gaining a better understanding of the rules and compound properties that govern the penetration and efflux of drug-like small molecules into Gram-negative bacterial pathogens. This NOFO also supports the preclinical development of novel Gram-negative antibacterial therapeutics based on the tools and models hereby developed. Applications must focus on one or more of the following Gram-negative bacterial pathogens: carbapenem-resistant Acinetobacter, carbapenem-resistant Enterobacterales (CRE), and/or MDR Pseudomonas aeruginosa. Projects should complete assay/tool/model development prior to the end of the third year of the project period and initiate discovery activities to demonstrate its utility in supporting a corresponding medicinal chemistry program to generate a lead chemical series with demonstrated activity against one or more targeted Gram-negative bacteria. This NOFO will also support subsequent preclinical development of a promising lead antibacterial. Given the complex challenges of this research, this initiative encourages applications from multi-disciplinary teams composed of relevant experts in areas such as bacterial physiology, microbiology, bacterial membrane biology, medicinal chemistry, pharmacology, computation, and specialized technologies (microscopy, spectroscopy, electrophysiology, machine learning, etc.), as appropriate. Collaboration with, and utilization of, the NIAID Chemistry Center for Combating Antibiotic-Resistant Bacteria (CC4CARB), is recommended for completion of project relevant medicinal chemistry tasks. Close collaboration between academic and industry partners is highly encouraged to optimally combine innovative basic science with drug discovery expertise and proper access to compound libraries more typically available from industry. Examples of assay and model development activities include, but are not limited to: Quantitative cellular (or model system) assays to measure drug penetration and efflux, independent from standard minimum inhibitory concentration (MIC) testing; Innovative quantitative assays to measure drug concentrations in the bacterial cytoplasm and/or periplasmic space; Innovative technologies for dissecting and assessment of the kinetics of drug penetration and efflux from bacteria; and Computational algorithms for describing/predicting physical-chemical properties/guidelines needed by small molecules for optimal Gram-negative penetration and efflux avoidance. Applicants should demonstrate the utility of the developed tools and/or assays to predict and measure potency of candidate therapeutics against Gram-negative targets through one or more approaches. For example, using the developed models and/or assays to guide a medicinal chemistry campaign aimed at producing a novel chemical series with Gram-negative activity; screening existing libraries using the computational algorithms developed as a tool to find compounds with Gram-negative activity; or profiling existing libraries of compounds with known Gram-negative activity. Applications including the following will be considered non-responsive and will not be reviewed: Projects that do not focus on at least one select Gram-negative pathogen (carbapenem-resistant Acinetobacter, carbapenem-resistant Enterobacterales, or MDR Pseudomonas aeruginosa); Projects focused only on Gram-positive bacteria or Mycobacterium tuberculosis; Projects that do not focus on penetration and efflux of small molecules; Applications not containing a Milestone and Timeline attachment; Applications proposing Clinical trials; and Research on HIV/AIDS.

Talbot Arts invites grant applications for its Community Arts Development (CAD) Program, aimed at funding arts activities that serve Talbot County, Maryland. This program aligns with Talbot Arts' mission to engage all community members through targeted outreach, fostering equitable access to diverse and inclusive local arts activities. The simplified application process, accessible support, and transparent evaluations are designed to create an even playing field for all applicants, ensuring that the focus remains on the artistic merit and community impact of proposed activities. The CAD program primarily targets non-profit and government-related organizations that provide artistic experiences for citizens and visitors to Talbot County. A particular emphasis is placed on bringing arts to underserved communities, including individuals in healthcare settings, the economically disadvantaged, seniors, and those with special needs. The impact goal is to broaden participation in the arts, enriching the lives of these specific groups and the wider community by making artistic expression and engagement more accessible. Priorities for funding include proposals demonstrating strong artistic merit and organizational effectiveness—the ability of the applying organization to successfully carry out the proposed activity. Crucially, Talbot Arts seeks projects that exemplify service to the community, focusing on how well the proposed activity or program will benefit students, residents, and guests of Talbot County. This strategic focus ensures that grants are awarded to initiatives that can demonstrate both artistic quality and tangible community benefit. Expected outcomes include an increase in diverse and inclusive local arts activities, particularly in underserved areas, and a more engaged community through participation in the arts. While specific measurable results are not detailed in terms of quantifiable metrics within the provided text, the criteria of "organizational effectiveness" and "service to the community" imply an expectation of successful project implementation and positive community reception. Grants typically range from $1,000 to $24,000, with an overall program size between $100,000 and $500,000, supporting activities for a duration of one year, specifically from July 1, 2024, through June 30, 2025.

To enhance community engagement, neighborhood identity, public safety strategies, repairs or upgrades to improve overall safety, positive interactions/outcomes and messaging along with fostering resident collaboration. This program is intended to reduce violent and other crime, spur neighborhood investment and development from within and out, reduce code violations, and more, through Association and resident-led projects and programs with respect to resident health and safety, enhancing dignity, aging in place, and other necessary quality of life repairs. Neighborhoods have the opportunity to assist residents in experiencing value through “community”, and how this and partnerships support strength and stability. Eligibility: Application is open to not-for-profit Neighborhood Associations that are registered (or will partner with an Association who is registered) with the City of Kansas City and with the State of Missouri. Application Period: Applications will open on May 14, 2024, and close on June 21, 2024.

This funding opportunity provides financial support for community development projects that improve facilities, infrastructure, and public services for low- and moderate-income residents in specific areas of San Diego County.

The Albert W. Rice Charitable Foundation is inviting applications for its grant program, which aims to support and promote high-quality educational, human services, and health care programming for underserved populations. This initiative is deeply aligned with the foundation's mission to address critical community needs, particularly within the city of Worcester and its surrounding towns in Massachusetts. The foundation's long-standing commitment to these areas reflects a strategic priority to foster community well-being and equitable access to essential services. The grant program primarily targets nonprofit organizations that serve the residents of Worcester and nearby communities in Massachusetts. The beneficiaries are diverse, encompassing individuals and families requiring support in education, health, and human services. The overarching impact goal is to strengthen the social fabric of these communities by empowering organizations that provide direct services to those most in need, thereby contributing to a healthier, more educated, and more supported population. The foundation's priorities and focus areas are clearly defined: education, health, and human services. Within these broad categories, the foundation seeks programs that demonstrate a commitment to underserved populations. While the specific outcomes are not explicitly detailed as measurable results in the provided information, the implicit expected outcomes involve improved access to quality services, enhanced educational opportunities, better health outcomes, and strengthened human service provisions for the target demographic. From a strategic perspective, the Albert W. Rice Charitable Foundation operates with a theory of change centered on supporting local nonprofit organizations as key agents of positive societal change. By providing financial grants, the foundation enables these organizations to expand their reach, enhance their programs, and ultimately create a tangible, beneficial impact on the lives of individuals in Worcester and its adjacent towns. Grant awards typically range from $15,000 to $25,000, though they can extend from $10,000 to $40,000, with durations of either one or two years, indicating a commitment to both short-term impact and sustained support for effective initiatives.

The Southern Monterey County Foundation (SMCF) offers grants to organizations that serve the communities of Southern Monterey County, specifically King City and all points south, excluding the coastal region. The foundation's mission is to support nonprofit organizations with strong leadership and the capacity to provide essential community resources and services. This grant program directly aligns with SMCF's mission by channeling funds to local initiatives that address critical needs within its defined service area. The target beneficiaries of these grants are residents and communities in Southern Monterey County. The impact goals include measurable improvements in identified community needs, the establishment of new community programs, and the expansion of existing ones that tackle high-priority issues. The SMCF aims to foster stronger, more resilient communities by investing in projects and programs that yield tangible benefits for the local population. In 2020, the foundation prioritized specific types of requests. These include funding for specific projects or one-time costs designed to produce a measurable impact on an identified community need. Additionally, grants are given to establish or expand community programs that address high-priority community issues or needs. These priorities reflect the SMCF's strategic focus on outcomes-based funding and its commitment to addressing pressing local challenges. Eligibility for these grants extends to 501(c)3 nonprofit organizations, public programs (such as schools, parks, and public health initiatives), and church-sponsored activities that benefit a broader community beyond their own membership. Organizations and collaboratives that are not legally incorporated can also apply, provided they have a 501(c)3 fiscal sponsor. The foundation's strategic priorities include supporting a diverse range of organizations capable of delivering impactful services, emphasizing fiscal responsibility through the fiscal sponsor requirement for unincorporated groups. The expected outcomes of the SMCF grant program are positive and measurable changes in Southern Monterey County communities. This includes addressing specific community needs, fostering the growth of vital community programs, and enhancing the overall well-being of residents. The foundation's theory of change appears to be that by strategically investing in projects and programs with clear objectives and measurable results, it can empower local organizations to drive meaningful and sustainable improvements in the region.

This funding opportunity supports innovative research projects that explore how climate change affects cancer risks, treatment, and survivorship, with a focus on developing solutions to mitigate these impacts and address health inequities.

The "Advanced Development and Validation of Emerging Molecular and Cellular Analysis Technologies for Basic and Clinical Cancer Research" grant aims to fund exploratory research projects that further develop and validate innovative technologies for analyzing molecular and cellular aspects of cancer, with the goal of improving cancer research, detection, diagnosis, treatment, and understanding of health disparities.

This grant provides funding for researchers to investigate the biological mechanisms behind adverse effects related to anti-beta-amyloid immunotherapy in Alzheimer's disease, with the goal of developing strategies to protect the blood-brain barrier and improve treatment safety.

This funding opportunity is designed for eligible institutions to expand and modernize facilities that breed Specific Pathogen Free non-human primates, essential for advancing HIV/AIDS research.

This funding opportunity supports U.S.-based organizations in developing and testing effective cancer interventions that improve health outcomes for diverse populations across the entire cancer control continuum, particularly in under-resourced communities.

The Michigan Office of the Environmental Justice Public Advocate in the Department of Environment, Great Lakes and Energy (EGLE) offers the Environmental Justice (EJ) Impact Grant program. This program is designed to reduce environmental health burdens and impacts within Michigan’s Environmental Justice communities. The core mission of this grant aligns with the broader goal of promoting environmental equity and public health, particularly in areas disproportionately affected by environmental issues. The primary target beneficiaries of this program are residents within Michigan’s Environmental Justice communities. The overarching impact goal is to positively affect these residents by funding place-based and equity-focused projects. This direct focus on communities facing environmental injustice ensures that the grant addresses critical needs where they are most prevalent, aiming for tangible improvements in their living environments and health outcomes. The program prioritizes several key areas for funding. These include community improvement projects aimed at enhancing public health, initiating or expanding monitoring of background pollution levels in air, water, or soil (with air monitoring equipment classified as air quality sensors and not for regulatory use), new or improved equipment or management techniques to improve indoor air quality in schools, and the remediation/redevelopment of contaminated or blighted sites. These priorities reflect a comprehensive approach to environmental justice, addressing both pollution and its direct impacts on community well-being. Expected outcomes include measurable improvements in public health through community projects, enhanced understanding of pollution levels via monitoring, better indoor air quality in schools, and the revitalization of environmentally degraded areas. The program has a total of $20,000,000 available, with a maximum of $500,000 per applicant. This substantial funding allows for significant, impactful projects. Eligible applicants include federally recognized Tribes, community-based non-profit organizations (including grassroots and frontline organizations), schools, institutions of higher education, and local governments, reflecting a strategic approach to engage diverse stakeholders in achieving environmental justice.

The purpose of this NOFO is to support projects to test prospective multi-sectoral preventive interventions that address social determinants of health in populations that experience health disparities. These research projects will be part of the Multi-Sectoral Preventive Interventions (MSPI) Research Network, which will also include a Coordinating Center (NOFO xxx). Funded under a cooperative agreement, projects participating in the MSPI Research Network will collaborate to share approaches, methods, and data, working closely with NIH Institutes, Offices and Centers. Applicants applying to this NOFO are encouraged to review the Coordinating Center NOFO to fully understand the MSPI Research Network structure and activities. This NOFO solicits bi-phasic research projects proposed in UG3/UH3 Phased Innovation Awards Cooperative Agreement applications. Funding for the UG3 phase (phase I) will be used to demonstrate sufficient preparation, feasibility and capacity to meet foundational milestone targets specific to the work proposed. A UG3 project that meets its milestones will be administratively considered by NIH and prioritized for transition to the UH3 award (phase II). Applicants responding to this NOFO must address specific aims and milestones for both the UG3 and UH3 phases.

This grant provides funding to non-profit organizations in Southern California for innovative projects that support long-term recovery from the Palisades and Eaton Wildfires, focusing on housing stability, mental health, and assistance for underserved communities.

This funding opportunity provides support for organizations to implement and evaluate a mental health campaign aimed at reducing suicide rates among disproportionately affected populations, such as veterans, rural communities, and LGBTQ individuals.

This funding opportunity supports researchers at various institutions to conduct basic experimental studies involving human participants, aimed at advancing our understanding of fundamental biological and behavioral processes.

The "Effectiveness of School-Based Health Centers to Advance Health Equity" grant aims to fund research into how school-based health centers can effectively address the health needs of underserved school-aged children, particularly in managing and preventing chronic illnesses and understanding how these centers can improve health outcomes for at-risk groups such as immigrant youth and those in rural areas.

This Funding Opportunity Announcement (FOA) encourages research grant applications directed toward developing next-generation human cell-derived microphysiological systems (MPS) and related assays that replicate complex nervous system architectures and physiology with improved fidelity over current capabilities. Supported projects will be expected to enable future studies of complex nervous system development, function and aging in healthy and disease states.

The City of Bakersfield is offering competitive grants for property and/or business owners within designated Downtown business district corridors: 18th, 19th streets and Wall Street Alley (between F and Q streets), and H Street and Chester Avenue (between 24th Street and Truxtun Avenue). The grants are specifically intended for large-scale exterior façade improvements to eligible properties and applicants within these areas. This initiative is funded by $1.5 million in American Rescue Plan Act (ARPA) funding, demonstrating a commitment to local economic recovery and revitalization. While the prompt asks for "foundation mission alignment," the context indicates this is a city-led grant, and its mission is aligned with urban development and supporting local businesses impacted by economic downturns. The target beneficiaries for this program include small businesses (defined as having no more than 500 employees), non-profit organizations (tax-exempt under Section 501(c)(3)), and businesses within "impacted industries." Impacted industries are those that experienced a negative economic impact during the pandemic, specifically citing tourism, travel, and hospitality. Other industries are considered impacted if they experienced at least 8 percent employment loss from pre-pandemic levels or comparable economic impacts. The impact goal is to stimulate economic recovery and enhance the aesthetic and functional appeal of the downtown business corridors, thereby fostering a more vibrant and attractive commercial environment. The program's priorities and focuses are clearly on exterior façade improvements. The City anticipates awarding funding to 4-6 projects, with individual grants ranging from $10,000 to $100,000. For awarded funding of $100,000 and over, a 10% private investment match is required, along with a public hearing before the City Council. This matching requirement encourages community investment and shared responsibility in the revitalization efforts. The grant duration is two years, providing a reasonable timeframe for project completion. Expected outcomes include visible improvements to the downtown business districts, increased private investment in the local economy, and support for businesses and non-profits that have been economically impacted. The measurable results are tied to the number of projects funded (4-6 anticipated), the total amount of ARPA funding allocated ($1.5 million), and the specific improvements made to property exteriors. The strategic priority here is the revitalization of key downtown commercial areas, using ARPA funds to mitigate the economic effects of the pandemic and promote long-term community resilience and growth. The theory of change posits that by investing in exterior improvements and supporting local businesses, the City can create a more appealing and economically robust downtown core, attracting more visitors and fostering greater community engagement.