Grants for Nonprofits - Health

This funding opportunity provides additional financial support for early-stage cancer researchers who have made significant progress in their work, allowing them to extend their research efforts and move towards greater independence in their scientific careers.

This funding opportunity supports educational and mentorship programs that encourage undergraduate and post-baccalaureate students from diverse backgrounds to pursue careers in genomics research.

This funding opportunity announcement (FOA) invites research projects that seek to explain the underlying mechanisms, processes, and trajectories of social relationships and how these factors affect outcomes in human health, illness, recovery, and overall wellbeing. Types of projects submitted under this FOA include studies that prospectively assign human participants to conditions (i.e., experimentally manipulate independent variables) and that assess biomedical and/or behavioral outcomes in humans to understand fundamental aspects of phenomena related to social connectedness and isolatedness. NIH considers such studies as prospective basic science studies involving human participants that meet the NIH definition of basic research and fall within the NIH definition of clinical trials (see, e.g., NOT-OD-19-024) Types of studies that should submit under this FOA include studies that prospectively assign human participants to conditions (i.e., experimentally manipulate independent variables) and that assess biomedical or behavioral outcomes in humans for the purpose of understanding the fundamental aspects of phenomena without specific application towards processes or products in mind. Applications proposing studies that include but not limited to model animal research or observational studies involving humans should submit under the companion Clinical Trials Not Allowed version of this FOA.

The City of Jurupa Valley's Community Service Grant Program aims to support local organizations that demonstrate effectiveness in fundraising and volunteer service for community programs, with a focus on fostering self-sufficiency. The program provides mini-grant funding for projects that benefit residents within Jurupa Valley, encouraging organizations to develop stable private funding sources and discouraging over-reliance on City financial assistance for ongoing operations. This aligns with the City Council's goal to support robust community programs while promoting sustainable financial practices among local non-profits. The target beneficiaries of this grant program are the residents of Jurupa Valley, who will benefit from social welfare, educational, charitable, athletic, cultural, or recreational programs. Non-profits awarded grants, up to $5,000 each, are expected to implement projects or programs that directly serve and improve the general community. The overarching impact goal is to enhance the quality of life and well-being for Jurupa Valley residents through diverse and beneficial community initiatives, ultimately strengthening the social fabric of the city. The program prioritizes organizations with current 501(c)(3) tax-exempt status that engage in activities for a public purpose within Jurupa Valley. Funding is specifically prohibited for certain uses, including salaries, scholarships, debt satisfaction, religious or political purposes, and mass mailings that violate the Political Reform Act. Eligibility also excludes organizations where City Council members are on the board, those involved in lawsuits against the City, or those engaging in prohibited or adverse activities to the community's health and safety. These restrictions ensure that grants are directed towards transparent, community-focused, and legally compliant initiatives. Expected outcomes include the successful implementation of various community-benefiting programs and projects, leading to tangible improvements in the social, educational, and cultural landscape of Jurupa Valley. While specific measurable results are not detailed, the emphasis on organizations demonstrating effectiveness in fundraising and volunteer services suggests an expectation of program sustainability and community engagement. The City Council's strategic priority, as adopted in Resolution No. 2014-48, is to support programs that benefit residents and promote the City, ensuring that all funding contributes to a public purpose.

This funding opportunity supports tourism-related projects and events in Cowlitz County, Washington, aimed at attracting visitors and enhancing the local hospitality experience.

This funding opportunity supports researchers investigating new and existing risk factors for liver cancer, focusing on population-based studies to improve understanding and prevention of the disease in the U.S.

This funding opportunity supports U.S. research institutions and cancer centers in developing innovative treatments for limited-stage small cell lung cancer by combining immunotherapy with advanced radiation therapies.

The purpose of this funding opportunity announcement (FOA) is to solicit applications for pilot projects to elucidate a role for understudied proteins associated with rare diseases. Awards will support generation of preliminary data and/or tools around eligible understudied protein(s).Funding Opportunity Description Introduction The National Center for Advancing Translational Sciences (NCATS) at the National Institutes of Health (NIH), is transforming the translational science process so that new treatments and cures for disease can be delivered to patients faster. NCATS strives to develop innovations to reduce, remove or bypass costly and time-consuming bottlenecks in the translational research pipeline in an effort to speed the delivery of new drugs, diagnostics and medical devices to patients. This funding opportunity announcement (FOA) aims to promote innovative research to increase knowledge of understudied proteins associated with rare diseases. The submission of small research grant (R03) applications is encouraged from institutions and organizations proposing projects leading to a better understanding of eligible proteins listed below. Small research (R03) grants provide flexibility for initiating discrete, well-defined projects that realistically can be completed in one year and require only limited levels of funding. This program supports different types of projects including, but not limited to, the following: Pilot or feasibility studies; Small, self-contained research projects; Development of research methodology; and/or Development of assays to support compound screening projects; Development of human cell or animal based models. These awards will support generation of preliminary data and tools around eligible understudied protein(s) with the intent of elucidating the function of these proteins in the context of rare disease and obtaining sufficient preliminary data and/or research resources for subsequent grant applications and/or drug discovery projects. These grants are non-renewable. This Funding Opportunity Announcement does not accept applications proposing clinical trial(s). Background The human genome has revealed a great deal about the human proteome, though significant portions of the genome remain understudied. Only a subset of expressed proteins demonstrates the requisite properties to serve as targets for the development of therapeutics. Many bona fide drug targets likely remain to be studied in the Druggable Proteome (DP), which can be defined as the fraction of proteins which have the ability to bind drug-like molecules. The term "drug-like" refers to the physical, biochemical, and pharmacological attributes of small molecule compounds that are generally recognized to be required for efficacious clinical drugs in humans. While the number of proteins in the DP is upwards of 4,500, the existing clinical pharmacopeia is represented by only a few hundred targets, leaving a huge swath of druggable biology unexploited. The expanded exploration of the relationship between the protein and the rare disease phenotype, or the development of a useful tool or reagent can accelerate research into a previously understudied protein. Many interesting and critical biological processes and potential therapeutic avenues remain unexplored because an initial catalyzing event (e.g., association with a biologic process or phenotype, creation of tools or reagents for the protein, etc.) has not yet occurred. The purpose of this FOA is to spark such catalyzing events through the support of small R03 awards to identify novel drug targets for the treatment of human disease, specifically rare disease Objectives and Scope The goal of this specific solicitation is to provide a needed opportunity for the collection of preliminary data around the role of understudied proteins associated with rare diseases. This FOA will provide funding to support research that will characterize new targets for treatment of human disease among the understudied proteins of the Druggable Proteome. These projects should be carried out in a short period of time with limited resources as defined by the funding mechanism. It has been recognized through workshops and publications that understudied proteins become illuminated when (1) there are tools to study the protein (e.g., tools that modulate protein activity) and/or (2) there is biochemical, cellular, or animal model evidence of disease/physiological relevance. This FOA was developed to address the need for expanded research and validation experiments on eligible understudied protein(s), with the intent of producing preliminary data to address the lack of biochemical, cellular, or animal model data associated with many understudied proteins. It is expected that the award will be used to obtain preliminary data and/or research resources for subsequent grant applications and/or drug discovery projects. The NIH supports research on a broad range of diseases that are defined as rare; that is diseases affecting fewer than 200,000 individuals in the United States (per the Rare Disease Act of 2002). Collectively, there are an estimated 7,000 rare diseases, which affect approximately 25-30 million people in the United States. Most are serious or life-threatening, with a disproportionate number of rare diseases affecting children. At this time, effective treatments are available for fewer than 5%. The IDG Program has linked over 6,000 proteins to rare diseases, with over 80% of these proteins considered extremely understudied. For the purposes of this FOA, eligible proteins are those that have an association with rare disease through data mining of the encyclopedia of rare disease annotations for precision medicine (eRAM) and Orphanet, are considered understudied (those proteins that lack small molecule binders and/or have limited biological characterization) and are within a protein family that is traditionally considered druggable.

This funding opportunity provides financial support to public housing authorities, nonprofits, and other eligible organizations to hire service coordinators who help residents of public and Indian housing communities access resources for economic and housing self-sufficiency.

This grant provides funding to organizations in Northeast Georgia that work to prevent childhood trauma and promote resilience among young people from birth to age 26.

The NIH Research Education Program (UE5) supports research education activities in the mission areas of the NIH. The overarching goal of this UE5 program is to support educational activities that encourage individuals from diverse backgrounds, including those from groups underrepresented in the biomedical and behavioral sciences, to pursue further studies or careers in computational genomics and data science research. To accomplish the stated over-arching goal, this NOFO will support creative educational activities with a primary focus on: Courses for Skills Development Specifically, this UE5 program will support faculty members at minority-serving institutions (MSIs) to create undergraduate or masters degree courses in computational genomics, data science, or a combination of these topics. Support for this activity will be provided by the Educational Hub for Enhancing Diversity in Computational Genomics and Data Science, created through RFA-HG-22-002. For developing skills in computational genomics and data science, these courses will leverage the resources of NIH cloud computing platforms such as NHGRIs AnVIL and the All of Us Researcher Workbench.

The William Penn Foundation is offering a grant of $500,000 to $1 million over three years to projects that increase access to mental health services for caregivers and young children in Philadelphia, particularly those facing barriers such as low income, cultural or linguistic issues, with a focus on expanding services in high-risk areas and advocating for relevant policies.

This funding opportunity provides financial support to nonprofits and government agencies for projects that help prevent homelessness and ensure housing stability for seniors in North County San Diego.

The Cow Creek Umpqua Indian Foundation offers grant opportunities for nonprofit 501(c)(3) organizations and local governmental bodies within Douglas County, Oregon. Focusing on Basic Needs, Abuse Prevention and Intervention, Education, Health and Wellness, and Community Support, the Foundation aims to fund projects that have a significant impact within the communities of Coos, Deschutes, Douglas, Jackson, Josephine, Klamath, and Lane Counties. With a maximum grant amount of $15,000. The Foundation emphasizes support for small grants that contribute meaningfully to the project or program, limiting organizations to one proposal per year unless specified otherwise. A final report is required from all grantees before reapplying. Grant renewed every year. Grant Annual Fall opening/closing deadlines: March 2nd to September 1st

The District of Columbia Child and Family Services Agency (CFSA) is offering a grant for its Home Visitation and Parent Education & Supports Program. This initiative aims to bolster family wellbeing and build protective factors within families. The program's core mission aligns with CFSA's goal to prevent child abuse and neglect by strengthening parent-child bonds, promoting healthy child development, and enhancing overall family functioning. The agency seeks to achieve this through innovative, community-based prevention programs. The primary beneficiaries of this program are parents and caregivers within the District of Columbia, particularly those who would benefit from home visitation, parent education, and prevention services. The impact goals are to provide families with service navigation, connecting them with governmental and community resources, offer wrap-around services such as food and clothing, and deliver high-fidelity, nationally recognized, evidence-based programs. Ultimately, the program strives to improve the mental and emotional health of children during their early years, increase protective factors, and significantly reduce the risk of child abuse and neglect. The program prioritizes innovative approaches, including video technology, motivational interviewing, tailored curricula, and engaging activities based on evidence-based or evidence-informed models. CFSA is specifically looking to fund programs that creatively strengthen the attachment between parents and their children. The expected outcomes include a stronger parent-child bond, enhanced healthy child development, improved family functioning, and a reduction in child abuse and neglect incidents. Measurable results will likely stem from the implementation of these evidence-based programs and the demonstrated improvements in family wellbeing and protective factors. CFSA's strategic priority is to fund innovative and community-based child abuse and neglect prevention programs. Their theory of change is that by equipping parents and caregivers with essential tools and resources, and by fostering strong parent-child attachments through evidence-based interventions, they can significantly improve children's mental and emotional health in early life. This approach, by increasing protective factors, directly addresses and aims to mitigate the root causes of child abuse and neglect, thereby enhancing overall community well-being.

The Ottawa County Community Foundation (OCCF) annually awards Community Grants to support charitable programs and initiatives across diverse fields including education, health, social services, economic development, natural resources, and the arts. These grants are funded through various sources such as Unrestricted and Donor Advised Funds, alongside annual donations. Eligible applicants include nonprofit 501(c)(3) organizations located in or serving Ottawa County, who must submit their proposals exclusively via the Foundation’s online application portal between January 1 and March 1 at 11:59 p.m. each year.

The Jeannette F. Schlobach grant program, funded by the Community Foundations of the Hudson Valley, offers $10,000 to $100,000 to nonprofit organizations in Dutchess, Putnam, or Ulster Counties, New York, that provide services such as case management, housing, education, job training, and health services to residents impacted by poverty, with a focus on historically marginalized and under-funded communities.

This grant provides funding for researchers and institutions to develop advanced imaging and biomarker technologies that improve the early detection of aggressive cancers and precancerous lesions, ultimately enhancing patient outcomes and clinical decision-making.

This funding opportunity supports innovative community-based projects aimed at reducing health disparities related to dementia and cognitive decline among underserved populations as they age.

The C. J. Stafford and Dot Stafford Memorial Trust supports charitable organizations that serve residents of San Diego County, California. The trust invests in local initiatives that strengthen community well being and address needs across several fields of interest. Priority program areas include arts and culture, education, health, and human services. Average grants range from 5,000 to 7,500 dollars, with total annual giving of about 50,000 dollars. Funds may be used for projects or programs that benefit San Diego County residents and are consistent with the trust mission. Eligible applicants must be public charities qualified under Section 501(c)(3) of the Internal Revenue Code. Applications are accepted only through the online grant application form or accessible alternative; no other formats are accepted. Grants are geographically limited to San Diego County, California. Applications are due May 1, 2024. Grant duration is not specified. Additional information is available through the trustee portal referenced by Wells Fargo.