Grants for Public and State controlled institutions of higher education - Health

This funding opportunity provides financial support for community-led initiatives in Ohio aimed at improving maternal health outcomes, particularly for underserved populations, by addressing healthcare access and social determinants of health.

The Black, Indigenous, and People of Color Fund aims to promote equity for Native American, Latino, African, Arab, and Asian communities in Maine through leadership investment, policy change, and alleviating race-based disparities. The fund focuses on organizations with BIPOC leadership and involvement, prioritizing racial equity, health, leadership development, and economic opportunities. It offers two-year general support grants of up to $10,000 per year, with the first grants awarded in 2024. Organizations must be based in Maine and meet specific community service criteria to qualify. Grant renewed every year. Grant Annual opening/closing deadlines: November 15th to February 15th

The objective of this research proposal is to develop physiologically based pharmacokinetic (PBPK) model-based mechanistic in vitro in vivo correlations (IVIVCs) for two major types of long acting injectables (LAIs) such as crystalline suspensions and polymer-based implants by considering their distinct characteristics. The goal of the project is to develop a bottom-up mechanistic PBPK model for these two LAI categories by accounting for the influence of critical formulation attributes of each LAI drug product type to predict its in vivo release mechanism. The model formulation parameters and relevant physiology should be informed with suitable in vitro and in vivo experiments. A suitable preclinical animal model can be used to validate the PBPK model based IVIVCs for both LAI suspensions and polymer based implants. The use of PBPK modelling provides a unique opportunity to understand how the physicochemical properties of drug molecules/polymer, implant specific properties, critical formulation attributes, and physiology, among other things, influence the in vivo release mechanisms of LAI drug products and their disposition characteristics. Moreover, once developed, a mechanistic PBPK model can help to define the 'safe space' for critical formulation attributes relevant to the reference listed drug (RLD) product, explain sources of PK variability and extrapolate predictions to human subjects by leveraging animal model data and by accounting for species-specific physiological differences.

This funding opportunity supports research projects that investigate the relationship between HIV and aging, focusing on improving health outcomes for older adults living with HIV, particularly in diverse and underserved populations.

The National Academy of Sciences Gulf Research Program is investing $50 million in the Gulf Futures Challenge to fund projects addressing critical challenges in the Gulf region. The Challenge aims to discover and promote innovative and transformative solutions by leveraging the talent and knowledge of the Gulf's people. The competition focuses on three main areas: energy transition, environmental change along the coast, and healthy and resilient communities. Up to ten finalists will receive up to $1 million in project development support, with two finalists awarded $20 million each to implement their solutions. Eligible applicants include nonprofits, state, local, and tribal governments, and academic institutions from Alabama, Florida, Louisiana, Mississippi, or Texas, with projects located within 100 miles of the Gulf coastline. The registration deadline is August 20, 2024, and the application deadline is September 20, 2024.

This funding opportunity supports collaborative cancer prevention and education programs in Indiana, specifically targeting high-burden cancers and underserved communities, with a focus on reducing risk behaviors and improving health outcomes.

This funding opportunity supports research projects that develop and implement effective tobacco use treatment services for cancer survivors across diverse clinical settings, with a focus on equitable access and reducing health disparities.

This funding opportunity supports graduate students from diverse backgrounds in neuroscience to complete their Ph.D. and transition into postdoctoral research positions, promoting career development and research training.

This funding opportunity provides financial support to organizations developing medical respite programs that offer short-term care for individuals experiencing homelessness who need a safe place to recover from illness or injury.

This funding opportunity supports U.S. institutions training addiction medicine and psychiatry fellows to improve substance use disorder treatment in underserved and rural communities.

This funding opportunity provides financial support for early-career researchers from diverse backgrounds to develop their skills in cancer research under the mentorship of experienced scientists, without leading independent clinical trials.

This grant provides funding for research to develop and test combined neuromodulation and behavioral treatment strategies for individuals with Stimulant Use Disorder, particularly targeting those with vulnerable traits like low executive function and impulsivity.

This funding opportunity supports research to improve stem cell-derived islet cells for transplantation therapies, targeting interdisciplinary collaborations among scientists and institutions focused on diabetes and cell biology.

The purpose of the Mentored Research Scientist Career Development Award in Tobacco Regulatory Research (K01) is to provide support and protected time (three, four, or five years) for an intensive, supervised career development experience in biomedical, behavioral, and social science research that will inform the development and evaluation of regulations on tobacco product manufacturing, distribution, and marketing and that will lead to research independence. Research projects must address the research priorities related to the regulatory authority of the Food and Drug Administration (FDA) Center for Tobacco Products (CTP) as mandated by the Family Smoking Prevention and Tobacco Control Act (FSPTCA), Public Law 111-31.

NLM wishes to accelerate the availability of and access to secure, complete data sets and computational models that can serve as the basis of transformative biomedical discoveries by improving the speed and scope of the curation processes.NLM wishes to accelerate the availability of and access to secure, complete data sets and computational models that can serve as the basis of transformative biomedical discoveries by improving the speed and scope of the curation processes. This Funding Opportunity Announcement is focused on automating curation of biomedical digital assets in support of Goal 1. Objective 1.1 of the NLM Strategic Plan 2017-2027: An important research direction will develop strategies for curation at scale." The ability to re-use, integrate or add to existing data sets will open new avenues of opportunity and can speed discoveries that will improve health. But this promise will go unrealized without advances in automated and autonomous curation. Objective 1.2: Automatic, autonomous curation strategies will allow for operational efficiency as well as accelerate the speed of discovery Digital curation involves characterizing, annotating, managing, and preserving digital assets such as research data sets, computational and other types of models, reusable visualization tools, and other digital assets. Proficient curation of digital assets maximizes their reuse potential, mitigates risk of obsolescence, reduces the likelihood that their long-term value will diminish or be lost, and helps assure reproducibility of research. The evolving digital ecosystem supports data-driven biomedical discovery by providing access to large quantities of biomedical and health-related data, to computational models and to open source software and code. The scope, scale and heterogeneity of digital data alone are vast, ranging from genome sequences to biomedical images, from observational health findings to environmental measurements, from family histories to sensor readings from personal trackers. As the amount and complexity of digital assets continue to grow, manual curation will not scale to meet future needs. At the same time, as researchers make research data sets, models and other tools available for new uses or re-analysis, it is important to minimize duplication and simplify the process of finding, managing, visualizing and mining all types of digital assets. To help researchers who want to find, interoperate and use these data sources to make new discoveries, and to share their findings so others can build upon them, the purpose of this funding announcement is to encourage applications for new approaches that (1) increase the speed and assure quality and security of storage techniques, retrieval strategies, annotation methods, data standards, visualization tools and other advanced data management approaches and (2) improve our ability to make biomedical data and other digital research assets findable, accessible, interoperable and reusable (FAIR).

The United States Agency for International Development (USAID) plans to invest in a five-year cooperative agreement titled GH Social and Behavior Change (SBC) Activity to support countries in achieving desired improvements in health and development outcomes.The GH SBC Activity will build upon current USAID investments in SBC research and programming, including both global and bilateral projects, to guide integration of SBC evidence and theory in development programming, support generation and use of new learning, strengthen local technical and organizational capacity, and drive local leadership of SBC programming for better, broader, and more sustainable results. The project will fulfill a global leadership function within SBC, working through new and existing partnerships to create opportunities for locally-driven, innovative, and cost-effective SBC programs; systematic integration of SBC best practices within public and private health systems; and generating, synthesizing, and catalyzing the application of evidence-based and theory-informed SBC in diverse program settings to accelerate achievement of global health and development goals.The strategic objective of the project is to increase implementation of theory-informed, evidence-based, locally-led SBC programming. While focused primarily on health, the project may address SBC needs in other sectors, with particular attention to areas of potential complementarity such as environmental conservation, agriculture, food security, and nutrition. Within the health sector, the project will maintain a substantive but non-exclusive focus on family planning, reproductive health (FP/RH) and reproductive empowerment; malaria; and maternal, newborn, and child health (MNCH), with attention to emerging pandemic threats and other infectious diseases. Considerations of USAID priorities such as localization, gender integration, youth engagement/integration, health systems strengthening, the inclusion of LGBTQI+ people, the inclusion of people with physical and cognitive disabilities, engaging the voices, skills, and experiences of allincluding marginalized and underrepresented groups such as racial, ethnic, and Indigenous communities and climate change, will be a focus across the project.Please see the Full GH Social and Behavior Change (SBC) Activity RFA under the "Related Documents" tab.

The purpose of the Pathway to Independence Award in Tobacco Regulatory Research (K99/R00) is to increase and maintain a strong cohort of new and talented independent investigators conducting research that will inform the development and evaluation of regulations on tobacco product manufacturing, distribution, and marketing. This program is designed to facilitate a timely transition of outstanding postdoctoral researchers with a research and/or clinical doctorate degree from mentored, postdoctoral research positions to independent, tenure-track or equivalent faculty positions

This grant provides funding for researchers to develop and test advanced imaging tracers that can help understand and treat mental health and neurodegenerative disorders in humans.

The purpose of this initiative is to: 1.Support mining of SCORCH data to identify cell types, transcripts, enhancers, or transcriptional networks that play a role in HIV/ART or SUD molecular responses 2.Support functional validation studies (e.g. epigenomic or transcriptomic manipulation, high throughput secondary screening, etc.) to confirm or deny a biological role for data-mined cell types, transcripts, enhancers, or transcriptional networks in HIV/ART or SUD molecular responses 3.Provide foundational knowledge for understanding SUD and/or HIV/ART molecular mechanisms and to generate validated targets that could serve as a foundation for new SUD or HIV therapeutics (including NeuroHIV cognitive phenotypes)

This funding opportunity is designed to support researchers exploring how RNA modifications affect brain aging and contribute to Alzheimer's disease and related dementias.