Grants for Public and State controlled institutions of higher education - Health

Reissue of RFA-MH-22-115 to comply with DMSP policy. The purpose of this Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative is to encourage applications that will develop and validate novel tools to facilitate the detailed analysis and manipulation of complex circuits and provide insights into cellular interactions that underlie brain function. Critical advances in the treatment of brain disorders in human populations are hindered by our lack of ability to monitor and manipulate circuitry in safe, minimally-invasive ways. Clinical intervention with novel cell and circuit specific tools will require extensive focused research designed to remove barriers to delivery of gene therapies. In addition to identification and removal of barriers, the need to specifically target dysfunctional circuitry poses additional challenges. Neuroscience has experienced an impressive influx of exciting new research tools in the past decade, especially since the launch of the BRAIN Initiative. However, the majority of these cutting edge tools have been developed for use in model organisms, primarily rodents, fish and flies. These cutting edge tools, such as viral delivery of genetic constructs, are increasingly adaptable to large brains and more importantly are emerging as potential human therapeutic strategies for brain disorders. A pressing need to develop tools for use in large brains, more directly relevant to the human brain is the focus of this initiative. The new tools and technologies should inform and/or exploit cell-type and/or circuit-level specificity. Plans for validating the utility of the tool/technology will be an essential feature of a successful application.

This funding opportunity supports researchers in planning high-risk, multi-center clinical studies focused on kidney, digestive, diabetes, and metabolic disorders, helping them develop essential protocols and administrative frameworks before conducting the actual trials.

This funding opportunity supports research to improve cancer care and outcomes for sexual and gender minority survivors by addressing their unique challenges and engaging community partners in the process.

This grant provides funding for researchers to evaluate community and societal programs aimed at preventing adverse childhood experiences and addressing social and health inequities.

This funding opportunity provides financial support to community organizations and health facilities to deliver hepatitis C treatment in accessible, non-traditional settings for people who inject drugs, aiming to eliminate health disparities and improve health equity.

The United Black Fund of Greater Cleveland (UBFGC) has announced the "Community Thrive" grant, a special funding opportunity designed to combat mental health issues and gun violence in the community. This initiative aligns with UBFGC's mission to identify and partner with organizations that are making a positive impact on the devastating effects of these issues, demonstrating a commitment to community well-being and social justice. The grant supports programs, resources, and support services that aim to improve mental health and/or reduce the incidence of gun violence, reflecting a strategic priority to foster a healthier and safer Cuyahoga County. The grant targets organizations serving Cuyahoga County that provide programming to support mental health or gun violence prevention/intervention work. The beneficiaries include youth and adults affected by depression, those at risk of suicide, individuals struggling with school violence/absenteeism, anger management, and social media addiction. In terms of gun violence, the grant aims to support families affected by gun violence, promote gun safety, and address gun culture and laws. The expected impact is a reduction in mental health crises and gun violence incidents, leading to improved community well-being and safety. The "Community Thrive" grant prioritizes projects that impact mental health wellness, including addressing depression, suicide prevention, school violence, anger management, and social media addiction. For gun violence prevention, the grant seeks innovative approaches such as education and awareness campaigns, and community-based interventions that tackle root causes. Specific areas of interest include preventing shootings in schools, universities, religious institutions, and retail locations, as well as supporting affected families. The grant also considers proposals addressing gun culture, gun safety, and gun laws. Applicants must be established organizations with a proven track record of at least three years, demonstrating their impact through data. They must serve Cuyahoga County and provide a minimum of one letter of support. A key criterion is that funding must be utilized for 80% programming and 20% operations and/or marketing. The organization must be a 501(c)(3) or have a fiscal agent, and a one-page strategic plan summary outlining the use of funds is required. The grant does not support one-time events, sponsorships, or fundraising campaigns, emphasizing a focus on sustained programming with a minimum execution period of one year, commencing January 1, 2024. These criteria reflect UBFGC's theory of change, which emphasizes evidence-based, long-term, and community-focused interventions.

This grant provides funding to support postdoctoral researchers from underrepresented backgrounds in transitioning to independent cancer research roles, with a focus on clinical trials and addressing cancer health disparities.

The purpose of this Funding Opportunity Announcement (FOA) is to encourage pilot and/or feasibility research in the following areas: 1) the development and pilot testing of new or adapted interventions to prevent or delay the initiation of substance use and/or the progression from use to misuse or disorder and 2) pre-trial feasibility and acceptability testing of services and service system research relevant to the prevention of substance use. In addition to the prevention of substance use, misuse and disorder, other outcomes of interest for the research supported through FOA include a reduction in negative sequalae such as deaths related to impaired driving, suicidal behavior (e.g., nonfatal and fatal attempts), and drug- or alcohol-related acquisition or transmission of HIV infection and viral hepatitis among diverse populations and settings.

This grant provides funding to institutions and organizations for establishing a centralized data coordination center that will manage and share research data on how socioenvironmental factors influence neurocognitive development and addiction risk.

This funding opportunity supports multi-site clinical trials for innovative treatments and interventions aimed at preventing or alleviating symptoms of Alzheimer's disease and related dementias, inviting applications from a diverse range of organizations and institutions.

This funding opportunity supports innovative research projects aimed at developing tools and treatments for diagnosing and mitigating injuries from radiation exposure during public health emergencies.

This funding opportunity announcement (FOA) encourages innovative research to develop, characterize, and improve animal models, biological materials, and novel technologies to better understand human health and disease. This FOA also seeks projects aimed at improving the diagnosis and control of diseases that interfere with animal use for biomedical research. The proposed project must have broad application to multiple NIH Institutes or Centers (ICs) to align with the Office of Research Infrastructure Programs (ORIP) trans-NIH mission. The proposed studies must explore multiple body systems or evaluate diseases that impact multiple body systems. Applications that develop models focused on a specific disease or area of research, or only propose studies primarily relevant to a single NIH IC will be considered not acceptable to this FOA.

This funding opportunity supports early-career clinical researchers in the U.S. to develop expertise in implementation science for substance use prevention and treatment through mentored clinical trials addressing the overdose crisis.

The "Development and Validation of Human Cellular Models for Alzheimer's Disease-Related Dementias (ADRD)" grant aims to fund the creation and testing of new, complex human cell models that accurately represent Alzheimer's and related dementias, with the goal of improving our understanding of these diseases and aiding in the development of potential therapies.

This grant provides funding for educational programs that improve the skills and knowledge of researchers analyzing large, complex datasets related to brain function, behavior, and social factors affecting health outcomes.

This funding opportunity supports innovative, time-sensitive research projects that enhance ongoing clinical studies related to arthritis, musculoskeletal, and skin diseases by leveraging existing patient data and samples.

This funding opportunity supports established biomedical data repositories and knowledgebases to enhance their operations and community engagement, ensuring they remain vital resources for researchers in the biomedical field.

This funding opportunity supports research that develops innovative tools to measure and enhance children's language development, particularly by engaging diverse communities and understanding environmental influences.

This funding opportunity supports community-based organizations in the Mid-Atlantic region to implement sustainable forestry initiatives that promote environmental justice, improve public health, and create green job opportunities in disadvantaged areas.

This funding opportunity provides financial support for researchers developing innovative, non-opioid treatments for various types of pain, with a focus on early-stage studies and collaboration with underrepresented populations.