Grants for Small businesses - Health

This Notice of Funding Opportunity (NOFO) invites applications from eligible small businesses to develop solutions for commercialization that can be used to enable regional clinician-to-clinician genomic medicine eConsult services. Specifically, we seek products, such as technologies or services, that will allow for the development and sustainment of eConsult services. Eligible United States small business concerns (SBCs) may submit Small Business Technology Transfer (STTR) Phase I, and Fast-Track grant applications. Small business applicants interested in submitting a Small Business Innovation Research (SBIR) grant application should submit to the related funding opportunity, PAR-24-106. SBIR and STTR are phased programs. The main objective in SBIR and STTR Phase I is to establish the technical merit and feasibility of the proposed research and development efforts. An SBIR and STTR Phase II continues the R&D efforts to advance the technology toward ultimate commercialization. At the conclusion of an SBIR/STTR Phase II, it is expected that the small business will fully commercialize their product or technology using non-SBIR/STTR funds (either federal or non-federal). Small businesses that are eligible to submit Phase II applications for projects that were supported with a Phase I SBIR or STTR award are expected to submit the regular Phase II application as a "Renewal" application based on the awarded Phase I SBIR or STTR project. Only one Phase II application may be awarded for a specific project supported by a Phase I award.

This grant provides researchers with access to advanced facilities and technical support for developing non-hormonal contraception and reproductive health products, without direct funding.

This funding opportunity provides financial support to nonprofit organizations, government entities, and select for-profits for programs addressing substance use disorders in West Virginia, focusing on areas such as foster care, youth prevention, recovery housing, and workforce development.

This grant provides funding for researchers worldwide to advance scientific understanding and treatment options for Angelman Syndrome, a rare genetic disorder affecting neurodevelopment.

This funding opportunity supports independent researchers in studying the prevention, diagnosis, and treatment of diseases related to military toxic exposures, benefiting Service Members, Veterans, and their families.

This funding opportunity supports research projects that explore the basic mechanisms and effects of trained immunity in the innate immune system, targeting a wide range of institutions and researchers interested in immune responses and related diseases.

This funding opportunity provides financial support to organizations that create and manage equine therapy programs aimed at improving the well-being and quality of life for disabled veterans and members of the Armed Forces.

The National Cancer Institute (NCI) intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for the RNA Modifications Driving Oncogenesis (RNAMoDO) Initiative. It aims to promote mechanistic research in the emerging area of RNA modifications that drive oncogenesis, with a focus on the central role of RNA modifications in translational reprogramming of cancer cells. RNA modifications have been recognized to exert a substantial impact on gene expression and function and their de-regulation has been linked to the cancer phenotype. In particular, recent insights point to a crucial role for mRNA, tRNA, and rRNA modifications in translational reprogramming during tumor initiation, progression, and adaptation to therapy. However, the molecular mechanisms underlying this reshaping of the translatome caused by dynamic changes in RNA modifications, and especially the interplay between different RNA modifications within and across RNA molecules during translation, are not understood and represent the focus of this initiative. Historically, the research community has largely pursued investigations of RNA modifications by studying single RNA species and modification types. However, elucidating how dysregulation of mRNA, tRNA, and rRNA modifications reprograms translation to drive oncogenesis is not likely feasible for any single research laboratory, but will require the combination of expertise in mRNA, tRNA and rRNA biology, translational regulation, and cancer research. To stimulate progress in this emerging field, the RNAMoDO program will support collaborative research projects, preferably using an MPI structure, on how modifications in mRNA, tRNA, and rRNA molecules can drive the oncogenic process through translational reprogramming. To be responsive to the NOFO, each project will also explore the impact of interactions between modifications residing on the same or different RNA molecules during translation. This Notice of Intent to Publish (NOITP) is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. The NOFO is expected to be published in the early Fall of 2024, with an expected application due date in November 2024. The NOFO will utilize the U01 mechanism for Research Project Cooperative Agreement (Clinical Trial Not Allowed). Potential applicants are encouraged to view the presentation of this initiative to the NCI Board of Scientific Advisors (BSA), available at: (https://videocast.nih.gov/watch=54423) beginning at 1 hour, 32 minutes, 52 seconds. Presentation slides are downloadable at https://deainfo.nci.nih.gov/advisory/bsa/0324/Maas.pdf.

This funding opportunity provides financial support to food recovery organizations and local jurisdictions in Orange County to improve infrastructure and expand programs that divert surplus edible food from landfills, in line with California's environmental mandates.

This funding opportunity supports research partnerships between technology developers and academic researchers to optimize and evaluate digital mental health interventions, particularly for underserved populations.

This funding opportunity supports research projects aimed at developing safe and effective medications for treating substance use disorders, particularly for substances like cocaine, methamphetamine, and cannabis, and is open to a wide range of eligible institutions and organizations.

This funding opportunity provides financial support for small businesses to develop innovative medical devices specifically designed to help children and young adults affected by substance use and addiction.

The National Institute on Aging is offering a grant for graduate students interested in aging-related research, providing funding and support for their doctoral dissertation projects and transition into postdoctoral positions in the field.

This funding opportunity supports researchers at higher education institutions and nonprofits to explore how dietary fats influence cancer growth and progression through molecular mechanisms, with a focus on preclinical studies.

The purpose of this program is to strengthen the behavioral health workforce in rural Northern Border Regional Commission (NBRC) service areas through supporting the recruitment and retention of behavioral health care providers.

This funding opportunity supports small U.S.-based businesses in developing and scaling innovative therapies using extracellular vesicles for regenerative medicine applications, such as tissue and organ repair.

Grant Title: Pilot projects to enhance utility and usage of data sets from the Molecular Transducers of Physical Activity Consortium (MoTrPAC) aims to fund small research projects that develop innovative methods to analyze and utilize MoTrPAC data, particularly focusing on how physical activity affects health, with a budget of up to $50,000 for one year.

This funding opportunity supports diverse research teams in developing innovative therapies for adult glioblastoma, focusing on translating promising treatments into early clinical trials.

This funding opportunity supports organizations in developing training and outreach initiatives to enhance the use of pediatric research data, focusing on childhood cancer and congenital anomalies.

This funding opportunity supports students enrolled in dual-degree medical and research training programs, helping them develop into independent physician-scientists through mentored research and clinical training.