Grants for Special district governments - Health

The grant titled "Mechanistic Investigations into ADRD Associated Protein Structures in Biological Settings" aims to use recent advancements in structural biology to study protein assemblies related to Alzheimer's disease and related dementias (AD/ADRD) in their natural environments within cells and tissues, with the goal of developing ligands that can identify and monitor these proteins in patients.

This funding opportunity supports the development of innovative computational tools to enhance the use of the human pangenome in genomic research, particularly for applications in cancer, aging, and diverse populations.

The purpose of this Funding Opportunity Announcement (FOA) is to diversify the translational research workforce for Alzheimer's disease and Alzheimer's disease-related dementias (AD/ADRD). This initiative will emphasize the development of skills in data science and drug discovery, and their application to various aspects of AD/ADRD research (from populations studies to research that can lead to new treatments and diagnostics, including all aspects of behavioral and social research). This initiative will support early career, independent investigators from diverse backgrounds to gain critical translational skills in data science and drug discovery. The long-term goal of this program is to develop a diverse translational workforce that can effectively participate in and/or lead a team-science, precision medicine approach to AD/ADRD treatment, prevention, early detection, and disease management and care.

This grant provides funding for research projects that implement screening and intervention strategies for alcohol, tobacco, and drug use among adult populations facing health disparities, such as racial minorities and low-income communities.

This funding opportunity supports researchers developing innovative technologies to enhance the delivery of treatments for HIV and substance use disorders, focusing on improving patient outcomes and understanding the effects of addictive substances.

This funding opportunity provides small grants to early-career researchers who have received specific NHLBI K awards, allowing them to expand their research projects or explore new studies that build on their previous work.

The "Early-Stage Dissemination and Implementation Research in Communication Disorders" grant aims to fund preliminary research projects that focus on improving the dissemination and implementation of treatments for hearing, balance, taste, smell, voice, speech, and language disorders, with a requirement to incorporate a Dissemination and Implementation (D&I) process model and other core D&I research elements.

The purpose of this NOFO is to seek applications for a Coordinating Center (CC) for the Multi-Sectoral Preventive Interventions (MSPI) Research Network. Members of the Multi-Sectoral Preventive Interventions (MSPI) Research Network, including the CC and separately funded research projects, will work collaboratively with the NIH to test prospective multi-sectoral preventive interventions that address social determinants of health in populations that experience health disparities. The MSPI Research Network will include the CC funded under this Cooperative Agreement and up to 10 Research Projects funded under the companion UG3/UH3 Phased Cooperative Agreement NOFO, Multi-sectoral preventive interventions that address social determinants of health in populations that experience health disparities. The CC will provide overarching support and guidance to the network in three domains: (1) administration, coordination, and communication; (2) methodology, data, and analytic support and consultation; and (3) community and other collaborator engagement and dissemination support. It is important that applicants for the CC also read the companion NOFO to understand the full mission and structure of the research network.

This Notice of Funding Opportunity (NOFO) solicits applications for one or more Data Coordinating Centers (DCCs) to support BRAIN CONNECTS, a networked consortium of Comprehensive Centers and Specialized Projects funded under RFA-NS-22-047, RFA-NS-22-048, and RFA-NS-22-049. The goals of these awards are to develop the research capacity and technical capabilities for comprehensive brain-wide connectivity mapping in mouse, human, and non-human primate (NHP). BRAIN CONNECTS projects will collect and process unprecedented volumes of anatomical data by scaling up cutting-edge acquisition modalities and analysis methods, to demonstrate the feasibility of collecting, reconstructing, analyzing, integrating, disseminating, and interpreting connectivity maps from entire brains. The resulting feasibility data from these awards are expected to inform NIH decisions on program continuation in a potential subsequent five-year funding period for production of brain-wide wiring diagrams. NIH expects to fund one or more BRAIN CONNECTS DCCs, which will collaborate with CONNECTS data generating projects to (1) coordinate activities of the BRAIN CONNECTS Network, (2) develop and harmonize common data processing pipelines, (3) integrate and disseminate data analytic tools and capabilities, (4) establish a unified knowledge base for connectivity data of diverse modalities, and (5) organize and implement outreach and engagement to the wider research community and the general public. Awards will be integrated into the BRAIN CONNECTS Network as a coordinated effort aimed at developing the ability to generate wiring diagrams spanning entire brains across multiple scales and species.

This funding opportunity supports research that explores how diet and lipid metabolism affect cancer growth and progression, encouraging collaboration between cancer researchers and nutrition experts.

This funding opportunity supports U.S. institutions in providing research education and mentorship for recent graduates from diverse backgrounds to prepare them for neuroscience doctoral programs.

This funding opportunity provides financial support for multidisciplinary research teams to investigate tuberculosis and its interactions with the host, aiming to improve understanding and treatment of the disease.

This funding opportunity provides financial support for innovative research projects that explore the complex relationship between adolescent social media use and mental health, particularly focusing on underserved youth populations.

This funding opportunity provides financial support for short-term projects that enhance local governance, infrastructure, education, and public safety in U.S. territories and freely associated states.

This funding opportunity supports collaborations between academic institutions and industry to develop innovative technologies that improve disease diagnosis, treatment, and management, particularly for underserved populations.

This funding opportunity supports research into how certain diabetes medications may influence cancer risk, encouraging studies that explore the underlying biological mechanisms involved.

This funding opportunity is designed for healthcare institutions and organizations in the U.S. to improve the management and outcomes of migraine patients in emergency departments.

This grant provides funding for innovative research using invasive brain recording and stimulation techniques in humans to improve understanding of the neural circuits involved in mental health disorders.

The purpose of the NINDS Research Program Award (RPA) is to provide longer-term support, and increased freedom and flexibility, to Program Directors (PDs)/Principal Investigators (PIs), to allow them to redirect their time away from the administrative burden of writing and managing multiple grant applications and towards engaging in the lab. This RPA affords investigators at most career stages the opportunity to advance their long-term research goals, rigorously explore exciting research opportunities, and mentor students and postdoctorates, which support and align with the mission of NINDS. RPAs will support the overall research programs of NINDS-funded investigators for up to 8 years, at a level commensurate with a PD/PIs recent NINDS support (Part 2, Section II). This funding stability will provide eligible investigators increased security, allowing them to undertake research projects that require a longer timeframe or to embark upon research that breaks new ground. Research activities outside of the NINDS mission, or traditionally supported by another NIH Institute or Center, will not be considered through this program. Benefits of the RPA include: A more stable funding environment, facilitating the pursuit of longer-term research goals; Flexible funding, enabling investigators to pursue research opportunities as they arise, not tied to specific aims; Reduced time spent writing grant applications and managing multiple grant awards, allowing investigators to spend more time conducting and overseeing research; More time for PDs/PIs to mentor and foster a diverse workforce in their laboratories. NINDS is committed to enhancing the diversity and inclusiveness of the neuroscience workforce. A diverse NIH-supported scientific workforce, including individuals from underrepresented groups, fosters scientific innovation, enhances global competitiveness, contributes to robust learning environments, and improves the quality of the research. See the Notice of NIH

This funding opportunity supports researchers conducting observational studies to improve understanding and treatment of musculoskeletal, rheumatic, and skin diseases, with a focus on patient outcomes and disease progression.