Grants for Special district governments - Health

This funding opportunity invites research institutions to join a collaborative effort aimed at advancing stillbirth research, particularly focusing on reducing stillbirth rates in vulnerable populations through innovative scientific approaches.

This funding opportunity provides financial support for the development of innovative informatics tools that will help researchers effectively utilize the human pangenome reference to advance genomics research across various applications.

This funding opportunity provides financial support to various organizations for developing and implementing public health strategies aimed at improving brain health and addressing the challenges of Alzheimer’s disease and related dementias, particularly for underserved populations.

To advance the field of patient-centered clinical decision support through research that tests tools and resources in real-world settings. The mission of the Agency for Healthcare Research and Quality (AHRQ) is to produce evidence to make healthcare safer, higher quality, and more accessible, equitable, and affordable, and to work within the U.S. Department of Health and Human Services and with other partners to make sure the evidence is understood and used. The purpose of this Notice of Funding Opportunity (NOFO) is to conduct research on patient-centered clinical decision support (PC CDS), a nascent area within the larger field of CDS. Through the AHRQ-funded Patient Centered Outcomes Research (PCOR) CDS Initiative and the CDS Innovation Collaborative specifically, PC CDS resources are now publicly available for interested researchers to further build upon, develop, and test, in real-world settings. Innovative research is needed to understand how to make traditional, clinician-facing CDS more patient-centered, while also engaging patients, families, and caregivers in a co-design process to design and implement these tools. BACKGROUND Clinical decision support refers to digital tools that are used to help inform patient care. Patient-centered clinical decision support (PC CDS), in contrast to traditional clinician-facing CDS, is CDS that focuses on the patient, or their caregiver, and facilitates their active involvement in healthcare decision-making with their clinicians. PC CDS uses information from patient-centered outcomes research findings and/or patient-specific information and has the potential to be transformative by enabling higher-quality care delivery and improved outcomes. PC CDS can also support shared decision making (SDM), which AHRQ defines as a collaborative process in which patients and clinicians work together to make healthcare decisions informed by evidence, the care team's knowledge and experience, and the patient's values, goals, preferences, and circumstances. PC CDS can also support shared care planning enabling patients, caregivers, and clinicians to work together to tailor a clinical plan to align with a given patients priorities and goals. PC CDS is a developing field and has the potential to increase the quality and experience of patient care. AHRQ’s CDS Initiative is supported by the Patient Centered Outcomes Research Trust Fund (PCOR TF) and is guided by AHRQ’s PCOR TF strategic framework (https://www.ahrq.gov/pcor/strategic-framework/index.html). Since 2016, AHRQ’s PCOR CDS Initiative has been building tools, concepts, frameworks, and conducting pilot projects. Much of AHRQ’s recent effort has focused on patient-centered CDS, and several past projects have generated resources that could be highly useful to the developing PC CDS field. Examples of these projects include AHRQ’s PC CDS Learning Network and CDS Connect, as well as a project that assessed the current state and future directions with PC CDS. Additional information for CDS projects is available on the PCOR CDS Initiative webpage. AHRQ’s most recent PC CDS project, the CDS Innovation Collaborative, or CDSiC, is a multi-component stakeholder-driven initiative that produced a rich set of resources and tested concepts around different aspects of PC CDS. As part of the CDSiC, four workgroups were formed, each around a specific area of PC CDS, with the charge to create products (e.g., frameworks, guides, checklists) that could be used in the clinical field to establish or measure use of PC CDS. These products could address clinical workflows or the development of CDS technologies, among other areas related to PC CDS. During the first two years of the CDSiC, these workgroups created numerous products that addressed PC CDS in different areas. These areas included CDS outcomes, trust and patient-centeredness, and scaling and dissemination. One workgroup also focused on the existing standards and regulatory frameworks that could impact the future uptake and use of PC CDS. Applicants can examine, using these products and tools, how PC CDS can support shared decision making and care planning among individuals with complex needs including older adults, people living with multiple chronic conditions, frailty, disabilities, and/or socioeconomic disadvantage and how this may foster the delivery of person-centered care. They may also study strategies to scale and spread effective tools including use in lower resourced and safety net instituions. Applicants responding to this NOFO must propose to use the resources developed by AHRQ's PCOR CDS Initiative, or any of the many products developed by the ongoing CDSiC, to further explore their usefulness, impact, and practical application in real-world settings. For example, CDSiC products that could be used may include the Taxonomy of Patient Preferences, Integration of Patient-Centered CDS into Shared Decision Making, Approaches to Measuring Patient-Centered CDS Workflow and Lifeflow Impacts, or the PC CDS Performance Measurement Inventory User Guide. Links to and descriptions of the products are available on the CDSiC Stakeholder Center webpage (https://cdsic.ahrq.gov/cdsic/cdsic-stakeholder-community-outreach-center ) The CDSiC's Innovation Center (https://cdsic.ahrq.gov/cdsic/innovation-center) developed a comprehensive report around measurement of PC CDS and created two pilot dashboards that can help clinicians understand and use Patient Generated Health Data. Additional information on other PCOR CDS projects is available at https://cds.ahrq.gov/about. Examples of Highly Responsive Projects include: A community hospital with a large priority population, selects from the CDSiC portfolio of projects generated by the Trust and Patient-Centeredness workgroup. The recipient selects the source credibility product from the Trust and Patient Centeredness workgroup and conducts a study to understand how their population perceives the information they receive from within their existing electronic health record (EHR) system. Patients provide input, and the approach is assessed against existing CDS tools, as well as the definition of PC CDS as defined by the CDSiC, to assess their level of patient-centeredness. A small startup company is developing applications (apps) to help patients improve their healthcare. The startup leverages two products from the CDSiC standards and regulatory frameworks workgroup: Advancing Standardized Representations for Patient Preferences to Support Patient-Centered Clinical Decision Support and an Environmental Scan that reveals opportunities to evolve standards and regulatory frameworks to advance PC CDS. The company works with a patient advocacy organization to co-design the patient-facing PC CDS app, uses standards to leverage existing patient generated health data (PGHD), and incorporates a final assessment as to the level of patient-centeredness of their technology. A primary care physician group is working to reduce clinician burnout with the goal of improving patient outcomes. The group looks at the CDSiC’s Taxonomy of Patient Preferences and assesses how they can incorporate these concepts into restructured workflows. The group then also uses CDSiC’s product called Approaches to Patient-Centered CDS Workflow and Lifeflow Impact, which provides a framework to help identify the optimal point for a patient-centered CDS tool’s deployment in a patient’s lifeflow. Their study will also assess how increased patient-centeredness in their CDS tools do not inadvertently have a negative impact on clinician workflows or experience. All projects are encouraged to: Incorporate Clinical Quality Language (CQL) and other HL7 standards into their project design, if appropriate for developing, integrating, (or modifying) their CDS with their EHR system or other health information technology (Health IT) components to become more patient-centered. OBJECTIVES AND SCOPE This NOFO aims to support innovative collaborative research to understand how clinical decision support tools in real-world settings can be improved to become more patient centered. Recipients will become part of an existing community of researchers who have an interest in PC CDS including AHRQ, the CDSiC, and other researchers. Interested applicants may include health information technology experts, patient advocates and representatives, clinicians, electronic health record developers, policymakers, payors, as well as leaders from research and academic medical institutions. All projects must: Utilize one or more of the products from the CDSiC or the PCOR CDS Initiative, which are available on the project website: cdsic.ahrq.gov, or another resource available from the PCOR CDS Initiative (cds.ahrq.gov), which includes the PC CDS Learning Network, CDS Connect, or AHRQ's Evaluation project that assessed the current state and future directions with PC CDS; If CDSiC products are used specifically, applicants must identify if any other frameworks are being used to evaluate the performance of their PC CDS (e.g., RE-AIM or other); Apply the definition of patient-centered CDS (available here: https://cdsic.ahrq.gov/cdsic/patient-centered-clinical-cds-infographic) and describe the degree to which each of the 4 elements are incorporated into the patient-centered CDS tool: knowledge, patient data, delivery, and use. Apply an equity lens, consistent with AHRQ's PCOR Strategic Framework. Apply at least 1 of the 4 priorities from AHRQ's PCOR Strategic Framework. Include meaningful and substantial participation from patients and/or patient representatives in the co-design, implementation, and evaluation of their research, to also be reflected in the proposed budget. Fully describe their research ecosystem. If developing or extending a digital tool, be mobile friendly to be more accessible to a broader population (for example, a patient-facing portal, website, etc.). If the research or tool will be incorporated into an EHR system, the facility must have a mature, functioning EHR system (e.g., the facility is not planning any significant system upgrade or migration). Otherwise, an alternative means to test and evaluate the selected CDS product can be described. If the research strategy intends to modify an existing clinical workflow that is currently clinician-focused, to become a patient-centric or patient-facing approach, then the strategy must include an evaluation component to characterize the performance of the PC CDS tool versus the previous clinician-facing workflow. If the proposed project plans to promote implementation of SDM, it should align with AHRQ’s definition of SDM (available here: https://www.ahrq.gov/sdm/about/index.html) and include at least one validated measure of SDM in its evaluation.

All work supported under this Grant shall focus on reducing health disparities for the populations across the state impacted by the high prevalence of cardiovascular disease (CVD), exacerbated by health inequities and disparities, social determinants, such as low incomes, poor health care, and unfair opportunity structures.  Financial Notes: National Cardiovascular 2304 Strategy 3B ADHS will identify one (1) Subrecipient to create or expand a (CHW) led community-clinical linkage partnership/program in one of the following counties: Apache, Cochise, Coconino, Gila, Graham, Greenlee, Mohave, Navajo, Pima, Pinal, Santa Cruz, Yavapai, or Yuma. The Subrecipient shall work with the CCL partnership/program to identify and train a team of CHWs to recruit for and implement the CCL partnership/program, providing a continuum of care and services which extend the benefits of clinical interventions and address social services and support needs leading to optimal health outcomes. Innovative Cardiovascular 2305 Strategies 3A and 3B ADHS will identify one (1) contractor to create or expand a community-clinical linkage partnership/program within Maricopa County. The Subrecipient shall work within a CCL partnerships/programs to identify and train dedicated CHWs (or their equivalents) through a CHW SDOH referral system to create and enhance community clinical links to identify social determinants of health {(SDoH) e.g., housing, transportation, access to care, and community resources} and respond to the individual social services and support needs within each county, providing a continuum of care and services which extend the benefits of clinical interventions and address social services and support needs leading to optimal health outcomes.

This grant provides funding to support postdoctoral researchers transitioning to independent faculty positions, focusing on innovative research in pain management and substance use disorders.

This funding opportunity supports the development of innovative molecular and genetic tools for neuroscientific research, enabling precise access to specific brain cell types across various vertebrate species, with a strong emphasis on collaboration, inclusivity, and resource sharing.

This funding opportunity supports doctoral students from underrepresented backgrounds in mental health research to complete their dissertation projects and advance their careers in the field.

This funding opportunity supports research projects that aim to improve access to and effectiveness of treatment for Alcohol Use Disorder, particularly for underserved populations, by addressing barriers and enhancing care delivery.

This funding opportunity supports researchers who have received a specific career development award to conduct small-scale projects that will help them become independent investigators.

The NIAID Research Opportunities for New and "At-Risk" Investigators to Promote Workforce Diversity (R01 Clinical Trial Optional), designated as PAR-22-241, is a funding opportunity issued by the NIH's National Institute of Allergy and Infectious Diseases (NIAID). The program targets New Investigators (NI) and At-Risk Investigators from underrepresented backgrounds in the biomedical, clinical, behavioral, and social sciences. New Investigators are those who have not previously secured substantial independent NIH funding, while At-Risk Investigators are those with previous funding but face a lack of funding in the following fiscal year unless a new grant is awarded. This initiative aligns with the goals of the 21st Century Cures Act to encourage new researchers, foster early independence, and support a more diverse scientific workforce. This funding announcement supports research relevant to the NIAID mission, including the study and treatment of infectious, immunologic, and allergic diseases. Research areas of focus include microbiology, immunology, infectious diseases, AIDS, transplantation, and emerging diseases. Although clinical trials are optional, applicants proposing NIH-defined clinical trials must consult with NIAID before submission. The funding opportunity is open to projects that advance diversity in the R01 investigator pool and those promoting representation from underrepresented groups in line with NIH’s interest in enhancing diversity across all health-related fields. To apply, investigators must be affiliated with U.S.-based higher education institutions or eligible nonprofits and for-profit organizations. This opportunity is also open to minority-serving institutions, such as Hispanic-serving Institutions, HBCUs, and Tribally Controlled Colleges and Universities. Non-domestic (non-U.S.) entities are not eligible, although foreign components of U.S. organizations are permitted. An essential part of the application process is an Eligibility Certification Letter from the applicant institution verifying the applicant’s eligibility and alignment with the program’s diversity objectives. Applications missing this letter will be considered incomplete. Funding levels are based on the project’s actual needs and are not capped, with a project duration of up to five years. NIAID also expects applicants to allocate funding in their budgets for mandatory attendance at a workshop designed to foster networking, collaboration, and professional growth among awardees, to be held every three years starting in 2025. Additional support for necessary accommodations for researchers with disabilities may also be included in the budget. The application process requires thorough adherence to NIH’s submission guidelines, which include registrations with SAM, Grants.gov, eRA Commons, and the acquisition of a UEI. Applications are accepted electronically through the NIH ASSIST system, Grants.gov Workspace, or a system-to-system solution. The next deadline cycle follows NIH’s standard due dates, with submissions due at 5:00 PM local time. Applicants are advised to submit early to address potential errors before the due date. Applications will be evaluated on scientific merit and alignment with program priorities, using criteria focused on the significance of the research, investigator qualifications, project innovation, approach, and institutional environment. Specific review criteria for clinical trials include the adequacy of study design, data management, and statistical analysis plans. Following peer review, recommended applications will receive secondary review by the NIAID advisory council. Final award decisions consider both scientific merit and relevance to NIAID’s mission and diversity goals.

This funding opportunity supports researchers in developing innovative theories and methods to better understand the complex genetic and non-genetic factors influencing human traits and health, with a focus on interdisciplinary approaches and diverse perspectives.

This funding opportunity provides support for mid-career and senior researchers to gain new skills and knowledge in dental, oral, and craniofacial research by collaborating with experts in different scientific fields.

This funding opportunity provides financial support to community-based organizations in Illinois to improve blood pressure control and address social factors affecting cardiovascular health among adults at high risk.

This funding opportunity provides financial support to a wide range of organizations for improving public health surveillance and treatment practices for inherited bleeding disorders, ultimately aiming to enhance health outcomes for affected individuals.

The purpose of the Delta Health Systems Implementation Program (DSIP) is to improve healthcare delivery in rural areas by implementing projects that will improve the financial sustainability of hospitals and allow for increased access to care in rural communities. These projects focus on financial and operational improvement, quality improvement, telehealth, and workforce development in hospitals in the in the rural counties and parishes of the Delta region. This program supports HRSA's collaboration with the Delta Regional Authority.

This grant provides funding to nonprofit organizations in Baldwin County, Alabama, and surrounding areas to support programs that assist people and animals facing hardship, neglect, or abuse.

This funding opportunity supports U.S. institutions and organizations in developing centers that integrate advanced translational science into cancer clinical trials, enhancing research on precision medicine and rare cancers.

This funding opportunity provides support for research projects that utilize health information technology to improve healthcare access, quality, and outcomes for underserved populations in the U.S. experiencing health disparities.

The grant titled "BRAIN Initiative: Engineering and optimization of molecular technologies for functional dissection of neural circuits" aims to support the development and enhancement of molecular tools that can specifically target brain cells, enabling the observation and control of neural circuits in experimental animals.