Grants for State governments - Health

This funding opportunity supports large-scale research projects aimed at combating antibiotic-resistant infections in various healthcare settings, targeting institutions and organizations dedicated to improving public health and patient safety.

This funding opportunity provides financial support for organizations to plan and host two virtual summits focused on improving maternal and child health in Wisconsin, targeting local and Tribal health agencies.

This funding opportunity supports researchers and organizations in developing and validating innovative screening assays to discover new chemical compounds for treating mental health disorders.

This funding opportunity supports researchers investigating genetic mouse models that experience early life challenges, aiming to advance our understanding of congenital diseases and developmental disorders.

This funding opportunity supports research centers focused on improving mental health and addressing health disparities related to HIV/AIDS, particularly for early-career and underrepresented researchers.

This funding opportunity supports experienced researchers in expanding their expertise and exploring new research directions in the fields of hearing, balance, smell, taste, voice, speech, and language sciences through intensive career development and basic experimental studies involving human participants.

This funding opportunity supports innovative educational programs that develop skills in cancer prevention, diagnosis, treatment, and patient care for professionals in the field.

The "Revision Applications for Incorporation of Novel NCI-Supported Technology to Accelerate Cancer Research" grant aims to encourage current NCI U01 research projects to incorporate new technologies from the NCI Innovative Molecular Analysis Technologies program, in order to enhance their original research and speed up scientific discoveries in cancer research.

This funding opportunity provides financial support for the development of affordable and culturally appropriate biomedical technologies aimed at reducing healthcare disparities among underserved populations in the United States.

This opportunity provides access to valuable biospecimens from a major study on brain development in children, aimed at researchers investigating adolescent health across various institutions and organizations.

This funding opportunity provides financial support to organizations that create long-term safe homes and comprehensive care for women and girls who have experienced sexual exploitation and trafficking.

The "Neuromodulation/Neurostimulation Device Development for Mental Health Applications" grant aims to fund the development of innovative brain stimulation devices or significant hardware/software enhancements to existing FDA-approved devices, with a focus on improving precision and delivery, for the treatment of mental health disorders.

This funding opportunity supports U.S. institutions and organizations in developing animal models and biological resources to advance research on Down syndrome and its related health conditions.

This funding opportunity provides support for the ongoing development and maintenance of valuable informatics tools and resources that enhance cancer research and management, benefiting researchers and the broader cancer community.

The purpose of the NIH Midcareer Investigator Award in Patient-Oriented Research (K24) is to provide support to mid-career health-professional doctorates for protected time to devote to patient-oriented research (POR) and to act as research mentors primarily for clinical residents, clinical fellows and/or junior clinical faculty. Section I. Funding Opportunity Description The overall goal of the NIH Research Career Development program is to help ensure that a diverse pool of highly trained scientists is available in appropriate scientific disciplines to address the Nation's biomedical, behavioral, and clinical research needs. NIH Institutes and Centers (ICs) support a variety of mentored and non-mentored career development award programs designed to foster the transition of new investigators to research independence and to support established investigators in achieving specific objectives. Candidates should review the different career development (K) award programs to determine the best program to support their goals. More information about Career programs may be found at the NIH Extramural Training Mechanisms website. The NIH Midcareer Investigator Award in Patient-Oriented Research (K24) is designed to enable mid-career clinician-scientists to: Devote more time to augment their capabilities in Patient-Oriented Research (POR); and Provide mentoring to junior clinical investigators in the conduct of POR (see below for definition). The K24 award is intended to provide protected time to mid-career clinical investigators to provide mentoring to junior clinical investigators, particularly K23 grantees, in POR and to stabilize the careers of these investigators. The intent is to allow these investigators to continue to conduct POR and be available as mentors in POR. It is expected that K24 recipients will obtain new or additional independent, peer-reviewed funding for POR as PD/PI and establish and assume leadership roles in collaborative POR programs. In addition, it is expected that there will be an increased effort and commitment to act as a mentor to beginning clinician investigators in POR to enhance the research productivity of both the K24 investigator and increase the pool of well-trained clinical researchers of the future. For the purposes of the K24 award, Patient-Oriented Research is defined as research conducted with human subjects (or on material of human origin such as tissues, specimens and cognitive phenomena) for which an investigator (or colleague) directly interacts with human subjects. This area of research includes: (1) mechanisms of human disease; (2) therapeutic interventions; (3) clinical trials, and; (4) the development of new technologies. Excluded from this definition are in vitro studies that utilize human tissues but do not deal directly with patients. In other words, patient-oriented research is research in which it is necessary to know the identity of the patients from whom the cells or tissues under study are derived. Studies falling under Exemption 4 for human subjects research are not included in this definition. See also the NIH Director's Panel on Clinical Research Report. NIH defines a clinical trial as "A research study in which one or more human subjects are prospectively assigned to one or more interventions (which may include placebo or other control) to evaluate the effects of those interventions on health-related biomedical or behavioral outcomes." (NOT-OD-15-015). NIH not only supports trials of safety and efficacy, it also supports mechanistic exploratory studies that meet the definition of a clinical trial and are designed to explore or understand a biological or behavioral process, the pathophysiology of a disease, or the mechanism of action of an intervention. These studies may focus on basic and/or translational discovery research in healthy human subjects and in human subjects who are affected by the pathophysiology of diseases and disorders. By addressing basic questions and concepts in biology, behavior, and pathophysiology, these studies may provide insight into understanding human diseases and disorders along with potential treatments or preventive strategies. NIH also supports biomarker studies that meet the definition of a clinical trial and that may provide information about physiological function, target engagement of novel therapeutics, and/or the impact of therapeutics on treatment response. NIH thus supports studies that meet the definition of clinical trials (as noted above) but do not seek to establish safety, clinical efficacy, effectiveness, clinical management, and/or implementation of preventive, therapeutic, and services interventions. Note: This Funding Opportunity Announcement (FOA) is designed specifically for applicants proposing to serve as the lead investigator of an independent clinical trial, a clinical trial feasibility study, or a separate ancillary clinical trial, as part of their research and career development. Applicants not planning an independent clinical trial, or proposing to gain research experience in a clinical trial led by another investigator, must apply to companion FOA Special Note: Because of the differences in individual Institute and Center (IC) program requirements for this FOA, prospective candidates are strongly encouraged to consult the Table of IC-Specific Information, Requirements and Staff Contacts, to make sure that their application is appropriate for the requirements of one of the participating NIH ICs. See Section VIII. Other Information for award authorities and regulations. Section II. Award Information Funding Instrument Grant: A support mechanism providing money, property, or both to an eligible entity to carry out an approved project or activity. Application Types Allowed New Resubmission Revision Renewal The OER Glossary and the SF424 (R&R) Application Guide provide details on these application types. Only those application types listed here are allowed for this FOA. Clinical Trial? Required: Only accepting applications that propose an independent clinical trial(s) Need help determining whether you are doing a clinical trial? Funds Available and Anticipated Number of Awards The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications. Award Budget Award budgets are composed of salary and other program-related expenses, as described below. Award Project Period The total project period may not exceed 5 years.

This grant provides funding for research on behavioral sleep interventions aimed at improving sleep and mental health outcomes for adolescents and young adults, particularly those from underserved populations.

This funding opportunity provides financial support for research sites to study Type 1 diabetic nephropathy by recruiting patients, conducting kidney biopsies, and collecting data to identify new treatment targets and improve precision medicine approaches.

Substance use needs to be better incorporated into interventions for the engagement and retention of sexual minority persons in prevention and care with attention to emergent interventions such as long-acting PrEP. Social determinants of health associated with HIV and problematic substance use such as homelessness and criminal justice involvement also demonstrate disproportionate impact among sexual and gender minorities and need attention. Changing self-definition of sexual minority status has implications for outreach and provider stigma and needs to be better integrated into interventions. This initiative will address these gap areas and support epidemiologic, intervention, and implementation research that incorporates attention to HIV as a syndemic including comorbidities such as STIs, HCV, and psychiatric disorder.

This grant provides funding to U.S. institutions to foster collaboration and support early-career researchers in benign urology through training, resource sharing, and professional development opportunities.

This funding opportunity supports a central coordinating center that will enhance collaboration and provide resources for research in nonmalignant hematology, particularly aimed at fostering the development of junior investigators and innovative projects across multiple institutions.