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Grants for Small businesses - Income Security and Social Services

Explore 279 grant opportunities

Translational Research in Maternal and Pediatric Pharmacology and Therapeutics (R01 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jul 7, 2026

Date Added

Nov 19, 2024

This funding opportunity supports research aimed at improving drug safety and effectiveness for pregnant individuals, breastfeeding individuals, and children, particularly those with disabilities, by developing innovative tools and models tailored to their unique health needs.

Education
State governments
Leveraging Extant Data to Understand Developmental Trajectories of Late Talking Children (R21 Clinical Trial Not Allowed)
$200,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 20, 2024

Date Added

Oct 17, 2023

This funding opportunity provides financial support for researchers to analyze existing data on late talking children, particularly focusing on underrepresented populations, to better understand their developmental trajectories and improve language outcomes.

Health
State governments
HEAL Initiative: Development of Therapies and Technologies Directed at Enhanced Pain Management (R41/R42 Clinical Trial Not Allowed)
$275,766
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Apr 4, 2025

Date Added

Sep 15, 2022

This funding opportunity supports U.S.-based small businesses in developing innovative, non-addictive therapies and technologies for improved pain management, addressing the opioid crisis through preclinical research and technological advancements.

Education
Small businesses
Blueprint Neurotherapeutics Network (BPN): Biologic-based Drug Discovery and Development for Disorders of the Nervous System (U44 Clinical Trial Optional)
$1,500,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Aug 19, 2024

Date Added

Jun 17, 2024

The Blueprint Neurotherapeutics Network for Biologics (BPN-Biologics) provides support for biologic-based therapeutic discovery and development, from lead optimization through phase I clinical testing. This Funding Opportunity Announcement (FOA) supports preclinical discovery and development of potential therapeutic Biotechnology Products and Biologics including, but not limited to, large biologic macromolecules, (e.g., proteins, antibodies, and peptides), gene-based therapies (i.e., oligonucleotide- and viral-based), cell therapies, and novel emerging therapies (e.g., microbial and microbiome therapies). Applicants will collaborate with NIH-funded consultants and can augment their project with NIH contract research organizations (CROs) that specialize in manufacturing, scaling, pharmacokinetics, toxicology, and Phase I clinical testing. BPN-Biologics awardee institutions retain their assignment of IP rights and gain assignment of IP rights from the BPN-Biologics contractors (and thereby control the patent prosecution and licensing negotiations) for biotherapeutic candidates developed in this program.

Education
Small businesses
National Center on Head Start Early Learning, Health and Family Engagement
$15,000,000
U.S. Department of Health & Human Services (Administration for Children and Families - OHS)
Federal

Application Deadline

Not specified

Date Added

Jun 27, 2025

This funding opportunity provides $15 million to organizations that will develop training and support resources for Head Start programs, focusing on improving early learning, health, and family engagement for children and families.

Income Security and Social Services
City or township governments
RFA C-25.1 Texas Diagnostic and Devices Company Awards
Contact for amount
Cancer Prevention and Research Institute of Texas
State

Application Deadline

May 1, 2024

Date Added

Apr 18, 2024

Funding available through this RFA supports the ongoing research and development of diagnostic tests and devices to treat, detect, diagnose, monitor, and assist in the treatment of cancer. Relevant areas include: Devices and assays for cancer detection, diagnosis, prognosis, monitoring, treatment and prediction of response or resistance to treatment Markers for cancer prevention and control, companion diagnostic to a therapy Development of diagnostic tests to distinguish high-risk early lesions Generally, at the time that an applicant applies to CPRIT pursuant to this RFA, the company has developed a commercial prototype of the device or a pictorial representation of the functional components/elements of the device. With respect to diagnostics, the company has developed assays that work on human samples and whose importance is well justified for development into clinical assays. The applicant should be working toward submitting an Investigational Device Exemption (IDE) or a 510(k) or Premarketing Approval (PMA) and is typically within one year from filing an IDE (or later stage work.) Potential applicants that are not at or near this stage of product development should consider applying for a Texas Seed Company Award. With appropriate justification, companies may use CPRIT funds to support studies that establish preclinical proof of concept, product validation, design, production, manufacturing and development, and clinical studies demonstrating safety and efficacy.

Business and Commerce
Small businesses
CFMC’s Small Opportunity Grants
$5,000
Community Foundation for Monterey County (CFMC)
Private
Rolling

Application Deadline

Not specified

Date Added

Nov 21, 2023

Program: CFMC Small Opportunity Grants Program Funder: Community Foundation for Monterey County (CFMC) Award Details: Grants typically range between $1,000 and $5,000, with larger grants up to $10,000 considered as exceptions. The grant amount can be used to support emerging organizations and ventures, urgent needs, and time-sensitive efforts where a small amount of money will make a difference. The grants are one-time and not ongoing program support. Eligibility: Eligible organizations include 501(c)3 nonprofit organizations, fiscally-sponsored organizations, and occasionally other unincorporated public benefit organizations serving Monterey County residents. Fiscal sponsors may submit applications for multiple sponsored groups. Individual organizations within a collaborative applying for a grant may also apply for their own Opportunity Grant as long as it is not for the same project as that of the collaborative. Businesses and individuals are generally not eligible, except for social enterprises associated with a local nonprofit. Application Process: Before submitting an application, it is recommended to review the Opportunity Grant Guidelines and application. A conversation with the program officer prior to submission is highly encouraged. The application process is fairly simple and online. Applications are accepted year-round, and decisions are usually made within two months of submission. Evaluation: A final report is required within one year of receiving the grant. The report should include a narrative evaluation that details how the grant was used, its impact on the organization or community, lessons learned, and next steps. To apply for CFMC Small Opportunity Grants Program or access additional information about eligibility criteria and guidelines, visit their Online Grants Manager at [https://www.grantinterface.com/Home/Logon?urlkey=cfmco](https://www.grantinterface.com/Home/Logon?urlkey=cfmco). For any questions or further assistance regarding eligibility or applying with a fiscal sponsor, contact the staff person for the specific grant opportunity or the Grantmaking Coordinator.

Capacity Building
Nonprofits
OJJDP FY25 Family-Based Alternative Justice
$750,000
U.S. Department of Justice (Office of Juvenile Justice Delinquency Prevention)
Federal

Application Deadline

May 8, 2026

Date Added

Mar 26, 2026

This funding opportunity provides financial support to organizations that help families at risk of involvement in the justice system by offering rehabilitation services and resources to keep parents and children together.

Law Justice and Legal Services
County governments
Strengthening Public Health Infrastructure in Maryland
$500,000
St. Mary’s County Health Department (SMCHD)
Local

Application Deadline

Not specified

Date Added

Nov 27, 2024

This funding opportunity provides financial support to organizations in St. Mary’s County that aim to reduce health disparities and improve health outcomes for vulnerable populations through culturally competent and evidence-based initiatives.

Health
Small businesses
Prevent Elder and Vulnerable Adult Abuse, Exploitation, Neglect Grant Program
$150,000
Michigan Department of Health and Human Services (MDHHS)
State

Application Deadline

Jul 1, 2026

Date Added

Jun 9, 2026

This funding opportunity provides financial support to nonprofit organizations, local health departments, and other eligible entities to implement programs that prevent abuse, neglect, and exploitation of older adults and vulnerable populations in Michigan.

Health
Nonprofits
Commercial Façade Improvement Matching Grant Program
$10,000
City of Santa Monica
Local

Application Deadline

Not specified

Date Added

Dec 3, 2024

This program provides matching funds to small businesses in Santa Monica for exterior improvements, prioritizing those owned by minorities, women, and LGBTQ+ individuals, as well as businesses serving low- and moderate-income areas.

Safety
City or township governments
Development of Animal Models and Related Biological Materials for Down Syndrome Research (R21 Clinical Trial Not Allowed)
$200,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 16, 2025

Date Added

Nov 26, 2024

This funding opportunity supports researchers in developing innovative animal models and biological tools to advance the understanding of Down syndrome and its related health conditions.

Health
State governments
BRAIN Initiative: New Concepts and Early-Stage Research for Recording and Modulation in the Nervous System (R21) (Clinical Trial Not Allowed)
$200,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Dec 10, 2024

This grant provides funding for innovative researchers to develop new technologies that can precisely record and manipulate neural activity in the nervous system, with a focus on enhancing inclusivity and collaboration across diverse fields.

Health
State governments
Van Wert County Foundation Grant
Contact for amount
Van Wert County Foundation
Private
Rolling

Application Deadline

Not specified

Date Added

Nov 24, 2023

The grant opportunity is open to organizations of all types across the USA, including nonprofits, startups, researchers, local governments, and small businesses. The grant applications are accepted bi-annually, with a spring cycle running from March 1 to May 1 and a fall cycle running from September 1 to November 1. To apply for the grant, applicants need to create an organizational and user account in the grants portal. The application can be saved as a draft and edited before submission. The grants portal also allows grantees to check the status of their grant, submit electronic grant reports if required, and access application history. All applicants are required to create an account using their email address as the username. They need to provide contact information and their organization's information, including the EIN/Tax ID number. Organizations should consolidate all applications into one user account for easy access to their full history of grants and requests. Applicants can manage their online accounts by editing contact information, beginning the application process, accessing drafts and submitted applications, and completing the reporting process for grant awards. If a grant writer works for multiple organizations, they should contact the Van Wert County Foundation to discuss their options. Before starting the application process, it is recommended to read the Grant FAQs provided on the website. To access the Grant Portal and start the application process, applicants can visit this link: [Grant Portal Link](https://www.grantinterface.com/Home/Logon?urlkey=VanwertGrants)

Capacity Building
Nonprofits
City of Pittsburg Facade Improvement Grant Program
$10,000
City of Pitsburg
Local

Application Deadline

Jun 30, 2024

Date Added

Jun 12, 2024

The City of Pittsburg Façade Improvement Grant Program aims to stimulate investment in the local business community by offering up to $10,000 for façade enhancements to eligible businesses. This initiative aligns with the city's mission to support and foster the growth of its local businesses, recognizing them as essential for community vitality, opportunity creation, and creativity. By focusing on visible improvements to storefronts, the program directly contributes to the beautification of public-facing areas and the overall image of the city. The primary beneficiaries of this program are small, brick-and-mortar businesses with public-facing storefronts located within Pittsburg city limits and holding an active City of Pittsburg Business License. Shopping centers with five or fewer tenants are also eligible. The program explicitly excludes home-based businesses and businesses that sell tobacco, alcohol, cannabis products, or adult materials. The impact goal is to create more inviting storefronts, improve neighborhood characteristics, encourage reinvestment in older buildings, and increase potential foot traffic for businesses, ultimately benefiting the businesses, their customers, and the wider Pittsburg community. The program prioritizes enhancements and beautification of public-facing building façades that will improve the image and characteristics of the building, the business, and the City. Specific focuses include signage, awnings, exterior paint (including anti-graffiti), architectural treatments, stucco, cladding, and/or siding repair, windows, front entrance doors, exterior lighting, planter boxes, and bicycle racks. The City seeks businesses that will provide the maximum return on investment and long-lasting benefits. A property-owner-led application is highly encouraged to ensure uniform projects, though individual tenants can also apply. The expected outcomes include a more aesthetically pleasing urban environment, increased business visibility, and a more inviting experience for customers. Measurable results will include the number of façades improved, the amount of grant funds dispersed (up to $10,000 per applicant from a $30,000 budget), and potentially qualitative feedback on improved neighborhood characteristics and increased foot traffic. The City's strategic priority is to invest in its local businesses to help them thrive, with a theory of change that by improving the physical appearance of business fronts, the city can stimulate economic activity, enhance community pride, and foster a more vibrant local economy.

Business and Commerce
Small businesses
Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 26, 2025

Date Added

Dec 22, 2023

This funding opportunity supports early stage researchers in pursuing innovative and high-risk scientific projects that significantly diverge from their previous work, without the need for preliminary data.

Education
State governments
HEAL Initiative: Translating Research to Practice to End the Overdose Crisis (R33 Clinical Trial Optional)
$750,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Mar 20, 2025

Date Added

Dec 18, 2024

This funding opportunity supports research projects that develop and implement effective strategies to reduce overdose deaths and improve addiction treatment across various settings, targeting diverse populations and addressing health disparities.

Education
State governments
Opportunities for HIV Cure Strategies at the Time of ART Initiation (R21 Clinical Trial Not Allowed)
$200,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 7, 2025

Date Added

Sep 20, 2023

This funding opportunity supports innovative research aimed at developing new strategies for curing HIV at the start of antiretroviral therapy, targeting researchers and institutions focused on reducing the HIV reservoir and improving immune responses.

Health
State governments
Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (Parent F32)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Sep 7, 2023

This funding opportunity supports postdoctoral researchers in biomedical and behavioral fields, providing mentorship and resources to help them develop into independent scientists.

Education
State governments
Rehabilitation Research Career Development Programs (K12 Clinical Trial Optional)
$850,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Mar 19, 2025

Date Added

Dec 6, 2024

This grant provides funding to support career development and mentoring for junior faculty in clinical rehabilitation fields, helping them transition to independent research roles that improve the health and quality of life for individuals with chronic disabilities.

Health
State governments