Grants for City or township governments - Science and Technology

The Arizona Department of Health Services (ADHS) Bureau of Women’s and Children’s Health (BWCH) oversees Adolescent Health programming to improve the health and well-being of young people in the state. As of 2005, BWCH has been administering state lottery funds for the prevention of teen pregnancies and sexually transmitted infections (STIs). According to the Arizona Vital Statistics, from 2011 to 2021, the teen birth rate for Arizona teenagers ages fifteen through nineteen (15-19) has declined from thirty-six point nine (36.9) to fifteen point three (15.3) per 1,000 females. The repeat birth rates of youth of the same age, who had already had a child decreased from 142.7 in 2011 to 135.8 per 1,000 in 2021. Despite the declines, birth rates for Arizona teens ages fifteen through nineteen (15-19)   exceeds   the   national   rate   of   thirteen   point   nine   (13.9)   in   2021 (https://blogs.cdc.gov/nchs/2023/01/20/7245/). Arizona's racial and ethnic groups exhibit significant disparities in teen pregnancy rates, with Hispanic, American Indian, and African American females aged nineteen (19) or younger experiencing the highest rates. In 2021, American Indian youth had a notably elevated pregnancy rate of sixteen point three (16.3) per 1,000 females, surpassing the state average of ten point six (10.6) per 1,000. Similarly, rates for Hispanic or Latino youth were fourteen point four (14.4) per 1,000, and for Black or African American youth, they were twelve point six (12.6) per 1,000, both above the state average, while rates for White Non-Hispanics six (6) per 1,000 and Asian or Pacific Islanders three point four (3.4) per 1,000 were considerably lower. Teen pregnancy is intricately linked with complex factors such as school failure, behavioral issues, and family challenges, which often hinder youths’ ability to avoid pregnancy. Positive Youth Development (PYD) programs present a promising approach by emphasizing the enhancement of protective factors over merely addressing risk behaviors. These programs have shown efficacy in reducing sexual risk behaviors, Human immunodeficiency virus (HIV), other sexually transmitted diseases (STDs), and unintended pregnancies. By fostering ongoing development and maturation, PYD programs empower youth to recognize and manage risk-taking behaviors, making them a viable strategy for teen pregnancy prevention (Gavin et al., 2010). According to the 2021 Arizona Surveillance STD case data, forty-nine percent (49%) of STD cases (chlamydia, gonorrhea, and syphilis) in Arizona were among adolescents under the age of twenty-five (25). Since 2019, the rate of chlamydia among teenagers fifteen through nineteen (15-19) years old has been slowly decreasing but still remains high at 2,031 per 100,000 in 2019 to 1,729 per 100,000 in 2021. For gonorrhea, the rate among these teenagers increased from 384 per 100,000 in 2019 to 467 per 100,000 in 2021. As for syphilis, in 2019, twenty-two (22) per 100,000 fifteen through nineteen (15-19) year-old teenagers were reported to have syphilis, increasing to twenty-six (26) per 100,000 in 2021. Regarding STDs/STIs, major disparities between Arizona’s racial and ethnic groups also persist. The Arizona 2021 Annual STD Report indicates that Black (994 per 100,000) and American Indian/Alaska Native (787 per 100,000) populations have consistently higher rates of chlamydia, the Black population (763 per 100,000) continues to have the highest rate of gonorrhea, and the American Indian/Alaska Native (172 per 100,000) and Black (123 per 100,000) populations have the highest rates of syphilis, surpassing their Hispanic, White, and Asian/Pacific Islander counterparts. Financial Notes: Approximately $700,000.00 will be available each Grant year for a five (5) year grant period to provide services to youth for the prevention of teen pregnancies and STIs. Annual funding for services will be provided during the state fiscal year, from July through June; Therefore, the first and last years of funding will be partial funding: first year funded upon award through June 30, 2025; fifth year from July 1, 2029 through September 30, 2029. Budgets will be reviewed annually and may be decreased based on: 1. Changes in state lottery funding allocations. 2. Failure to meet the number of youths proposed to be served; or meet the required program completion by youth for Teen Pregnancy Prevention Programming. 3. Failure to comply with Grant requirements. 4. Negative audit findings. 5. Failure to spend budget funds efficiently.

This funding opportunity provides financial support to nonprofit organizations in New York and Massachusetts that enhance their capacity to serve young people with intellectual and learning disabilities, mental health challenges, and substance use disorders, particularly those from historically marginalized communities.

This grant provides funding for U.S.-based organizations to develop and implement innovative tools that use Earth observation data to improve water resource management and address challenges like drought and water scarcity, in collaboration with end users such as water management agencies and utilities.

This grant provides funding to higher education institutions and organizations to improve faculty skills in using educational technology and assistive tools in special education programs, enhancing learning for students with disabilities.

The Lumpkin Family Foundation’s **Land, Health, Community (LHC) Grant Program** serves as its core philanthropic initiative, advancing the family’s long-standing commitment to holistic community well-being in East Central Illinois. At least half of the foundation’s annual grantmaking is directed to this region, with a focus on fostering prosperity, health, leadership, and environmental stewardship. Through the LHC program, the foundation seeks to nurture communities that are economically strong, physically and mentally healthy, socially engaged, and environmentally conscious—each element reinforcing the others to create long-term resilience and vitality. A central vision of the program is to strengthen local food systems and agricultural economies while supporting residents’ physical and mental health. The foundation encourages projects that promote access to healthy, affordable food, strengthen local farm businesses, and integrate sustainable land use practices. Equally important is the cultivation of social cohesion and civic capacity—empowering communities to collaborate on shared goals, retain talent, and attract new opportunities. The emphasis on leadership development and collaborative problem-solving underscores the foundation’s belief in community-driven progress. In response to growing awareness of mental health challenges, the Lumpkin Family Foundation has expanded the LHC program to include **nature-based mental wellness initiatives**. These efforts support programs that demonstrate the connection between engagement with nature and improved mental well-being. Priority is given to projects that help youth and young adults reduce screen time through outdoor experiences, provide self-care opportunities for mental health practitioners, and create healing environments for trauma-impacted individuals such as foster youth. The foundation recognizes the strong research-based link between time spent in nature and improvements in happiness, social connectedness, and emotional balance. Successful proposals often integrate multiple LHC focus areas, combining personal health, environmental stewardship, agricultural innovation, and mental wellness. The foundation particularly values programs that promote sustainable farming, develop green practices that add productivity while protecting the land, and build community capacity through education and collaboration. Preference is given to rural organizations and those located in **Coles County** and surrounding areas, reflecting the foundation’s deep roots in East Central Illinois. Through the Land, Health, Community Grant Program, the Lumpkin Family Foundation continues to invest in the long-term vitality of its home region. By uniting efforts in agriculture, health, the environment, and mental wellness, the program fosters communities that are not only economically stable but also socially vibrant and emotionally healthy—a living model of the foundation’s belief in the interdependence of land, people, and place.

The DOD Pancreatic Cancer, Translational Research Partnership Award is a funding opportunity designed to support collaborative research projects between clinicians and scientists, with the aim of accelerating the development and application of innovative ideas in pancreatic cancer treatment, prevention, diagnosis, and survivorship, and encouraging the reciprocal exchange of knowledge between basic and clinical science.

This funding opportunity supports innovative research projects aimed at making significant advancements in breast cancer prevention, diagnosis, and treatment, involving collaboration with breast cancer survivors as advocates.

This funding is available to the City of Diamond Bar for community development projects that benefit low to moderate-income residents through housing, public improvements, and economic opportunities.

The Research Infrastructure in the Social and Behavioral Sciences Program (RISBS) supports projects that create computational tools and data to facilitate basic research in the social and behavioral sciences that can lead to improved health, prosperity and security. Projects should be aimed at creating computational tools and data to enable research by social scientists. Examples include, but are not limited to, data collection or assembly efforts that result in new resources for a community of researchers or software platforms that facilitate data collection efforts by others. RISBS does not support research by PIs except in service of creation of the infrastructure. Innovation is especially encouraged. RISBS directly supports three key longitudinal surveys and panel studies that provide researchers with data on how American society functions and changes over time (and in 2010 were recognized as among the 60 most significant "discoveries or advances that... have had a large impact or influence on every Americans life... call[ed] the Sensational 60, in honor of NSFs 60th anniversary): The American National Election Study, which started in 1948 and has been funded by NSF since 1977, provides gold standard data on voting, public opinion, and political participation in U.S. national elections. The General Social Survey, a nationally representative interview survey of the U.S. adult population, collects data on a wide range of topics and has been funded by NSF since its inception in 1972. The Panel Study of Income Dynamics, a longitudinal survey of a nationally representative sample of U.S. families begun in 1968 (with NSF taking over most of its funding in 1980) collects data on a wide array of economic, social and health factors. The RISBS program administers separate solicitations for the American National Election Study (ANES), the General Social Survey (GSS) and the Panel Study of Income Dynamics (PSID). These solicitations have specific requirements and submission deadlines. Other infrastructure proposals may be submitted directly to the RISBS program at any time or transferred from other SBE programs following the respective programs submission guidelines. RISBS also collaborates with other programs in the social and behavioral sciences through a co-funding process to support projects that create especially valuable tools for researchers in those fields or are furthering innovations in research infrastructure. Prospective PIs may also be interested in the Human Networks and Data Science Program Infrastructure(HNDS-I), which supports proposals addressing the development of data resources and relevant analytic techniques that support research in the social, behavioral and economic sciences.Prospective PIs are strongly encouraged to contact the RISBS program officers and/or program officers from other SBE programs that may be applicable to the proposal before submitting to RISBS and to refer to the NSF Proposal Award Policies Procedures Guide (PAPPG) policies on duplicate or substantially similar proposals.

Proposers must retrieve the instructions document (zip file) associated with the application package for this opportunity as there is at least one required form that must be attached to the submitted proposal package. The National Aeronautics and Space Administration (NASA) Science Mission Directorate (SMD) released its annual omnibus Research Announcement (NRA), Research Opportunities in Space and Earth Sciences (ROSES) 2024 (OMB Approval Number 2700-0092, CFDA Number 43.001) on February 14, 2024. In this case "omnibus" means that this NRA has many individual program elements, each with its own due dates and topics. All together these cover the wide range of basic and applied supporting research and technology in space and Earth sciences supported by SMD. Awards will be made as grants, cooperative agreements, contracts, and inter- or intra-agency transfers, depending on the nature of the work proposed, the proposing organization, and/or program requirements. However, most extramural research awards deriving from ROSES will be grants, and many program elements of ROSES specifically exclude contracts, because contracts would not be appropriate for the nature of the work solicited. The typical period of performance for an award is three years, but some programs may allow up to five years and others specify shorter periods. In most cases, organizations of every type, Government and private, for profit and not-for-profit, domestic and foreign (with some caveats), may submit proposals without restriction on teaming arrangements. Tables listing the program elements and due dates (Tables 2 and 3), a table that provides a very top level summary of proposal contents (Table 1), and the full text of the ROSES-2024 "Summary of Solicitation", may all be found NSPIRES at http://solicitation.nasaprs.com/ROSES2024. This synopsis is associated with one of the individual program elements within ROSES, but this is a generic summary that is posted for all ROSES elements. For specific information on this particular program element download and read the PDF of the text of this program element by going to Tables 2 or 3 of this NRA at http://solicitation.nasaprs.com/ROSES2024table2 and http://solicitation.nasaprs.com/ROSES2024table3, respectively, click the title of the program element of interest, a hypertext link will take you to a page for that particular program element. On that page, on the right side under "Announcement Documents" the link on the bottom will be to the PDF of the text of the call for proposals. For example, if one were interested in The Lunar Data Analysis Program (NNH24ZDA001N-LDAP) one would follow the link to the NSPIRES page for that program element and then to read the text of the call one would click on C.8 Lunar Data Analysis Program (.pdf) to download the text of the call. If one wanted to set it into the context of the goals, objectives and know the default rules for all elements within Appendix C, the planetary science division, one might download and read C.1 Planetary Science Research Program Overview (.pdf) from that same page. While the letters and numbers are different for each element within ROSES (A.12, B.7, etc.) the basic configuration is always the same, e.g., the letter indicates the Science Division (A is Earth Science, B is Heliophysics etc.) and whatever the letter, #1 is always the division overview. Frequently asked questions for ROSES are posted at http://science.nasa.gov/researchers/sara/faqs. Questions concerning general ROSES-2024 policies and procedures may be directed to Max Bernstein, Lead for Research, Science Mission Directorate, at sara@nasa.gov, but technical questions concerning specific program elements should be directed to the point(s) of contact for that particular element, who may be found either at the end of the individual program element in the summary table of key information or on the web list of topics and points of contact at: http://science.nasa.gov/researchers/sara/program-officers-list. Not all program elements are known at the time of the release of ROSES. To be informed of new program elements or amendments to this NRA, proposers may subscribe to: (1) The SMD mailing lists (by logging in at http://nspires.nasaprs.com and checking the appropriate boxes under "Account Management" and "Email Subscriptions"), (2) The ROSES-2024 blog feed for amendments, clarifications, and corrections to at https://science.nasa.gov/researchers/solicitations/roses-2024/, and (3) The ROSES-2024 due date Google calendars (one for each science division). Instructions are at https://science.nasa.gov/researchers/sara/library-and-useful-links (link from the words due date calendar).

This funding opportunity provides financial support for research projects that aim to improve the inclusion, independence, and quality of life for individuals with disabilities, particularly focusing on underserved populations and critical issues affecting these communities.

The Southern Sustainable Agriculture Research & Education (SSARE) Education Grants program is designed to fund education and outreach activities that benefit the sustainable agriculture community. This grant directly aligns with SSARE's mission to promote efforts in farmer innovations, community resilience, business success, agricultural diversification, and best management practices. The core objective is to support projects that develop sustainable agriculture systems or move existing systems towards sustainability. The primary beneficiaries of these grants are farmers and farming communities, including those involved in indigenous agriculture producing for community food systems. Academic institutions, non-profits, non-governmental organizations (NGOs), 1890 land-grant university faculty/extension cooperators, 1862 land-grant universities, other colleges and universities, and government agencies are eligible to apply, acting as facilitators for these educational initiatives. The impact goals are centered on fostering a more sustainable, resilient, and economically viable agricultural sector through knowledge dissemination and practical application. Education Grants prioritize projects that clearly articulate what is being taught, to whom, and how the goals will be accomplished. Focus areas include experiential learning (demonstrations, on-farm tours, field days, workshops), integrative approaches (conferences, seminars, course curriculum), and reinforcement methods (fact sheets, bulletins, videos, online technologies). SSARE also encourages proposals on quality of life topics, such as heirs property, farmers’ markets, food hubs, local/regional processing, and urban agriculture systems, emphasizing the social health of farming systems. Expected outcomes include the adoption of sustainable agriculture practices, enhanced farmer innovation, increased community resilience, improved business success for agricultural enterprises, and greater agricultural diversification. Projects should yield results that are realistic, acceptable to farmers, logical, and capable of leading to tangible actions and benefits described in the proposal. The grant projects are strictly focused on education and outreach, with no research component, and are paid by reimbursement of allowable expenses. The foundation's strategic priorities are evident in the grant requirements, which mandate that project outcomes focus on sustainable agriculture systems and clearly demonstrate how education and outreach efforts will be implemented and evaluated. The theory of change underpinning this program is that by providing targeted education and outreach, knowledge and best practices will be transferred to farmers and communities, leading to the development and widespread adoption of sustainable agricultural methods and improved quality of life within farming systems. Project maximums are $50,000, with a duration limited to two years. Applicants from the Southern region, including Alabama, Arkansas, Florida, Georgia, Kentucky, Louisiana, Mississippi, North Carolina, Oklahoma, South Carolina, Tennessee, Texas, Virginia, Puerto Rico, and the U.S. Virgin Islands, are eligible. Farmers involved in these projects must have farming/ranching as their primary occupation or part-time farming with at least $1,000 of documented annual income from their operation, with exceptions for indigenous agriculture.

This funding opportunity provides $5 million to support the deployment and commercialization of innovative technologies in public transportation, aimed at federal, state, local, and tribal governments, as well as public transit providers and educational institutions.

The National Aeronautics and Space Administration (NASA) Headquarters has released a solicitation, titled Early Stage Innovations (ESI), as an appendix to the Space Technology Mission Directorate (STMD) umbrella NASA Research Announcement (NRA) titled "Space Technology Research, Development, Demonstration, and Infusion 2024 (SpaceTech REDDI 2024), on April 4, 2024. The ESI solicitation is available by opening the NSPIRES homepage at https://nspires.nasaprs.com/, selecting Open under "Solicitations," and searching "Early Stage Innovations (ESI24)" under Keywords. The Space Technology Research Grants (STRG) Program within STMD seeks proposals from accredited U.S. universities to develop unique, disruptive, or transformational space technologies that have the potential to lead to dramatic improvements at the system level performance, weight, cost, reliability, operational simplicity, or other figures of merit associated with spaceflight hardware or missions. The projected impact at the system level must be substantial and clearly identified. Only accredited U.S. universities are eligible to submit proposals. Teaming is permitted see solicitation for complete eligibility requirements as well as teaming restrictions. A Principal Investigator (see solicitation for restrictions) or Co-Investigator may participate in no more than two proposals in response to this solicitation. NASA encourages submission of ESI proposals on behalf of tenure-track or tenured faculty members at all U.S. universities and especially encourages proposals submitted on behalf of and/or that include as team members women, members of underrepresented minority groups, and persons with disabilities. The solicitation exclusively seeks proposals that are responsive to one of the following two topics: Topic 1 Computational Materials Engineering for Lunar Metals Welding Topic 2 Passive Lunar Dust Control through Advanced Materials and Surface Engineering NASA anticipates addressing other topics in future ESI Appendix releases. The financial and programmatic support for ESI comes from the Space Technology Research Grants Program within the Space Technology Mission Directorate. Awards are planned to start in January 2025. NASA plans to make approximately 6 awards as a result of this ESI solicitation, subject to the receipt of meritorious proposals. The actual number of awards will depend on the quality of the proposals received; NASA reserves the right to make no awards under this solicitation. STMD is strongly committed to ensuring that proposal review is performed in an equitable and fair manner that reduces the impacts of any unconscious biases. To this end, this Appendix will employ a Dual-Anonymous Peer Review (DAPR) process to evaluate proposals. Using DAPR, not only are proposers not told the identities of the reviewers, but the identities of the proposers (personnel and organization names) will not be shared with the reviewers until after the technical review of all anonymized proposals has been completed. All proposals must be submitted electronically through NSPIRES by an authorized organizational representative. Notices of Intent (strongly encouraged) are due by May 9, 2024, with proposals due on or before June 6, 2024, 5 pm Eastern. Detailed submission instructions and due dates are provided in the solicitation. Potential proposers and their proposing organizations are urged to familiarize themselves with the submission system, ensure they are registered in NSPIRES, and submit the required proposal materials well in advance of the deadline. All technical and programmatic comments and questions may be addressed by email to the Space Technology Research Grants Program Executive, at hq-esi-call@mail.nasa.gov. Responses to inquiries will be answered by email and may also be included in the Frequently Asked Questions (FAQ) documents located on the NSPIRES page associated with the solicitation; anonymity of persons/institutions who submit questions will be preserved.

The Visit BG Ohio 2025 Tourism Grant Program offers financial support ranging from $1,000 to $10,000 for projects, events, and activities that promote tourism, increase overnight stays, and provide economic benefits to the City of Bowling Green, with a focus on capital improvement, sports, conferences, festivals, large events, and arts and culture.

The Pennsylvania HOME-American Rescue Plan Supportive Services (HOME-ARP SS) funds can provide a broad range of supportive services to individuals and families that meet one of the qualifying populations as defined in Notice CPD-21-10: Requirements for the Use of Funds in the HOME-American Rescue Plan Program. Supportive services may be provided to individuals and families who are not already receiving the services outlined in the Notice through another program. Applicants may establish a separate supportive services activity or activities or may combine supportive services with other HOME-ARP activities. Notice CPD-21-10: Requirements for the Use of Funds in the HOME-American Rescue Plan Program HOME-ARP funding is provided by the U.S. Department of Housing and Urban Development (HUD) and administered by DCED. Financial Info: The minimum funding request for Supportive Services projects is $25,000. Up to 5% may be requested for administrative costs.

The FY24 PCRP Early Investigator Research Award supports prostate cancer-focused research opportunities for individuals in the early stages of their careers under the guidance of one or more designated mentors. This opportunity allows early-career investigators to develop a research project, investigate a problem or question in prostate cancer research, and further their intellectual development as prostate cancer researchers of the future. All application components for the FY24 PCRP Early Investigator Research Award are to be written by the Principal Investigator (PI), with appropriate direction from the mentor(s).Key elements of this award mechanism are as follows: Principal Investigator: The postdoctoral investigator is considered the PI of the application and must exhibit strong potential for and commitment to pursuing a career as an investigator at the forefront of prostate cancer research; however, the PI is not required to have previous prostate cancer research experience. The PI must have 3 years or less of postdoctoral research experience (excluding clinical residency or clinical fellowship training) as of March 31, 2025. The PCRP strongly encourages applications from PIs who demonstrate a commitment to pursuing a career focused on prostate cancer health disparity research. Mentor(s): Applications must include at least one mentor appropriate to the proposed research project who has experience in prostate cancer research and mentoring as demonstrated by a record of active funding, recent publications, and successful mentorship. The primary mentor can be a junior faculty member, in which case the PI is encouraged to include a secondary mentor with a more robust track record in prostate cancer research and mentorship. Applications that focus on prostate cancer health disparity should include at least one mentor with experience in prostate cancer health disparity research. The selected mentor(s) should also demonstrate a clear commitment to the development of the PI toward independence as a prostate cancer researcher. Research Approach: Proposed research ideas are required to address one or more of the FY24 PCRP Overarching Challenges. Projects that specifically address the FY24 PCRP Overarching Challenge to advance health equity and reduce disparities in prostate cancer are strongly encouraged. The scientific rationale and experimental methodology should demonstrate in-depth analysis of the research problem presented. The feasibility of the research design and methods should be well defined, and a clear plan should be articulated as to how the proposed goals of the project can be achieved. Inclusion of preliminary data relevant to prostate cancer and the proposed project is encouraged but not required. Any preliminary data provided should be from the PI, mentor(s), or member(s) of the collaborating team. Additionally, required resources should be identified and supported through documentation. Research involving human subjects and human anatomical substances is permitted; however, clinical trials are not allowed under this funding opportunity. Researcher Development Plan: The PI must outline an individualized, prostate cancer-focused researcher development plan, which should include a clearly articulated strategy for acquiring the necessary skills, competence, and expertise that will enable the PI to successfully complete the proposed research project and foster the PIs development as an independent prostate cancer researcher. An environment appropriate to the proposed mentoring and research project must be clearly described, although any deficiencies of resources and/or mentorship at the PIs institution can be mitigated through collaboration(s) with other institutions. If the PI will be utilizing resources at another institution to successfully complete the proposed project, then the PI is strongly encouraged to designate a co-mentor at the collaborating institution.Investigators are strongly encouraged to incorporate the following components into their study design, where appropriate, in order to maximize the potential impact of the proposed research project: authentication of proposed cell lines; statistical rigor of preclinical animal experiments; and incorporation of experiments to assess clinical relevance and translatability of findings. Studies utilizing data derived from large patient studies that include long-term health records, biospecimen repositories, and pre-existing research and apply state-of-the-art genomic and/or proteomic analysis, bioinformatics, and/or mathematical models to such data are also encouraged. Investigators are highly encouraged to provide a letter of support indicating access to and the availability of any resources required to support the study.A congressionally mandated Metastatic Cancer Task Force was formed with the purpose of identifying ways to help accelerate clinical and translational research aimed at extending the lives of advanced state and recurrent patients. As a member of the Metastatic Cancer Task Force, the CDMRP encourages applicants to review the recommendations (https://health.mil/Reference-Center/Congressional-Testimonies/2018/05/03/Metastatic-Cancer-Research) and submit research ideas to address these recommendations provided they are within the limitations of this funding opportunity and fit within the FY24 PCRP priorities.Innovative research involving nuclear medicine and related techniques to support early diagnosis, more-effective treatment, and improved health outcomes of active-duty Service Members and their Families is encouraged. Such research could improve diagnostic and targeted treatment capabilities through noninvasive techniques and may drive the development of precision imaging and advanced targeted therapies.Applications from investigators within the military services and applications involving multidisciplinary collaborations among academia, industry, the military services, the U.S. Department of Veterans Affairs (VA), and other federal government agencies are highly encouraged. These relationships can leverage knowledge, infrastructure, and access to unique clinical populations that the collaborators bring to the research effort, ultimately advancing research that is of significance to Service Members, Veterans, and/or their Families. If the proposed research relies on access to unique resources or databases, the application must describe the access at the time of submission and include a plan for maintaining access as needed throughout the proposed research.All projects should adhere to a core set of standards for rigorous study design and reporting to maximize the reproducibility and translational potential of clinical and preclinical research. The standards are described in SC Landis et al., 2012, A call for transparent reporting to optimize the predictive value of preclinical research, Nature 490:187-191 (http://www.nature.com/nature/journal/v490/n7419/full/nature11556.html). While these standards are written for preclinical studies, the basic principles of randomization, blinding, sample-size estimation, and data handling derive from well-established best practices in clinical studies.Clinical trials are not allowed. A clinical trial is defined in the Code of Federal Regulations, Title 45, Part 46.102 (45 CFR 46.102) as a research study in which one or more human subjects are prospectively assigned to one or more interventions (which may include a placebo or another control) to evaluate the effects of the interventions on biomedical or behavioral health-related outcomes.Studies that do not seek to measure safety, effectiveness, and/or efficacy outcome(s) of an intervention are not considered clinical trials.For the purposes of this funding opportunity, research that meets the definition of a clinical trial is distinct from clinical research. Clinical research encompasses research with human data, human specimens, and/or interaction with human subjects. Clinical research is observational in nature and includes:(1) Research conducted with human subjects and/or material of human origin such as data, specimens, and cognitive phenomena for which an investigator (or co-investigator) does not seek to assess the safety, effectiveness, and/or efficacy outcomes of an intervention. Research meeting this definition may include but is not limited to: (a) mechanisms of human disease, (b) diagnostic or detection studies (e.g., biomarker or imaging), (c) health disparity studies, and (d) development of new technologies.(2) Epidemiologic and behavioral studies that do not seek to assess the safety, effectiveness, and/or efficacy outcomes of an intervention.(3) Outcomes research and health services research that do not fit under the definition of clinical trial.Excluded from the definition of clinical research are in vitro studies that utilize human data or specimens that cannot be linked to a living individual and meet the requirements for exemption under 46.104(d)(4) of the Common Rule.The funding instrument for awards made under the program announcement will be grants (31 USC 6304).The anticipated direct costs budgeted for the entire period of performance for an FY24 PCRP Early Investigator Research Award should not exceed $300,000. Refer to Section II.D.5, Funding Restrictions, for detailed funding information.Awards supported with FY24 funds will be made no later than September 30, 2025.The CDMRP expects to allot approximately $6.24M to fund approximately 13 Early Investigator Research Award applications. Funding of applications received is contingent upon the availability of federal funds for this program, the number of applications received, the quality and merit of the applications as evaluated by peer and programmatic review, and the requirements of the government. Funds to be obligated on any award resulting from this funding opportunity will be available for use for a limited time period based on the fiscal year of the funds. It is anticipated that awards made from this FY24 funding opportunity will be funded with FY24 funds, which will expire for use on September 30, 2030.

The 2025 Massachusetts 250 Grant Program, offered by the Executive Office of Economic Development (EOED) through the Massachusetts Office of Travel and Tourism (MOTT), is a competitive grant designed to fund programming and interpretation related to the American Revolution in Massachusetts. The program aims to increase tourism and travel within the state by highlighting its pivotal role in the nation's founding. This aligns with a broader mission to promote Massachusetts' historical significance and attract visitors, thereby bolstering the state's economic development through tourism. The grant targets municipalities, public agencies, tribal entities, and nonprofit organizations (501(c)3, 501(c)5, or 501(c)6) operating in Massachusetts. Eligible projects must demonstrate a direct connection to the American Revolution, link to themes of revolution and independence, celebrate significant historical "firsts" in Massachusetts, or offer creative approaches to commemorating the nation’s semiquincentennial. The program emphasizes that grant funds can be utilized for both programming and marketing initiatives. The primary priorities and focus areas for this grant include fostering a deeper understanding of the American Revolution's impact in Massachusetts and enhancing the state's appeal as a historical destination. The grant's strategic priorities are centered on supporting projects that interpret and tell these stories effectively, ultimately driving increased tourism. This implicitly supports a theory of change where investments in historical programming and marketing lead to greater engagement, visitor numbers, and economic benefits for the state. Expected outcomes and measurable results include an increase in tourism and travel to and within Massachusetts, successful programming that engages visitors with the American Revolution, and effective marketing campaigns that raise awareness of Massachusetts' historical significance. While specific quantitative metrics are not detailed, the competitive nature of the grant and the emphasis on increasing tourism suggest that successful applicants will demonstrate a clear plan for achieving these outcomes and, presumably, for measuring their impact. The program anticipates awarding up to $1,500,000 in FY25, with individual grants ranging from $5,000 to $100,000. This substantial funding demonstrates the state's commitment to commemorating the American Revolution and leveraging its historical assets for economic growth. Eligibility also requires compliance with regulations such as the MBTA Communities Act for municipal applicants, good standing with the Commonwealth, and current tax payments, ensuring responsible use of public funds.

The Noble County Community Foundation, in partnership with the Foundation for Appalachian Ohio, is offering grants to nonprofits, schools, and public organizations for projects and programs that benefit Noble County residents and communities. This initiative aligns with the foundation's mission to advance opportunities within the county by addressing key areas of need, known as the Pillars of Prosperity. The program seeks to empower local efforts and unleash the potential within Noble County. The grant program targets individuals of all ages within Noble County. The core impact goal is to create opportunities, meet pressing needs, and foster the potential of the community. The focus is on supporting a wide range of projects and programs that contribute to the overall well-being and development of the county's residents. Priorities for funding are centered around five critical areas: arts and culture, community and economic development, education, environmental stewardship, and health and human services. The foundation emphasizes supporting efforts that are spearheaded by local individuals and organizations. While funding requests typically range from $500 to $2,500, larger requests may be considered based on their potential for significant impact within these priority areas. Expected outcomes include tangible improvements and advancements across the Pillars of Prosperity. Measurable results will likely be tied to the specific goals of each funded project, demonstrating how they address community needs and create opportunities. The foundation's strategic priorities are deeply rooted in community development and empowerment, with a theory of change that posits by investing in these key areas, the overall quality of life and future prospects for Noble County residents will be significantly enhanced.

This grant provides funding to support research and initiatives that promote diversity, equity, inclusion, and accessibility for individuals with disabilities in STEM fields and education.