Grants for For profit organizations other than small businesses - Science and Technology

This ISO seeks solution summary and proposal submissions for projects that fall within the scope of the ARPA-H mission Resilient Systems Office (RSO). RSOs interest areas will address systemic challenges across the healthcare and public health landscape by investing in cutting-edge technologies that address long-standing gaps in the quality, efficacy, and consistent availability of care.Aspects of todays health and public health systems remain fragile due to systemic challenges, which include rising healthcare costs, inadequate healthcare coverage for significant populations, outdated infrastructure, and health disparities among different demographic groups. Acute challenges, such as hospital closures, supply chain disruptions, staffing shortages, cyber-attacks, public health crises, and the emergence of new diseases, further exacerbate existing fragilities, making it more difficult to maintain high standards of care. These challenges are compounded by the fact that systems remain fragmented, hindering the ability to gain comprehensive insights, make informed decisions, develop tailored interventions, and share critical health information between stakeholders.RSO seeks solution summaries and proposals that drive innovations to enhance the adaptability, reliability, and interoperability of the health ecosystem. Of interest are innovations that foster flexibility and enable adaptation to system stressors, so that people and systems remain well-positioned to deliver high-quality care and improve health outcomes. The following interest areas categorize the ground-breaking research we seek to support:Sociotechnical System Innovation: Innovate user-centric digital health tools, platforms, technologies, and intervention models that improve outcomes across the health continuum, including prevention, diagnosis, and treatment of physical, mental, and behavioral health. Approaches to build trust in the healthcare system and distribute high-quality health guidance in an understandable manner that improves patient outcomes. Novel real-time measurement tools to track health outcomes, evaluate post-market performance of new interventions, and enable convergence on the most effective strategies to improve the quality of care, especially for underserved communities. Other population centered innovations to create more resilient communities and subpopulations. Innovations might include aggregate improvements to quality of care and better physical, mental, and behavioral health outcomes for the health ecosystem.Health Ecosystem Integration: Novel ways to collect, protect, secure, integrate, analyze, communicate, and present health data, including but not limited to advances in privacy, cyber security, artificial intelligence with enhanced patient safety properties, low-code or no-code technologies, semantic approaches, and rapid integration techniques. Strategies and technologies to leverage homes, community centers, pharmacies, and other accessible locations to enable new modalities of high-quality care, expand the reach of clinical research, or integrate end-user feedback to rapidly iterate prototype designs. Approaches to strengthen the connectivity and interoperability of health data and devices to 5 enable the safe, secure, and seamless exchange of information among healthcare providers, researchers, and stakeholders. Other novel approaches to increase the interoperability of health-related systems in support of improved health outcomes and enhanced transparency across the health ecosystem.Adaptive Antifragile Solutions: Creative approaches to enhance the stability and dependability of the health ecosystem through new adaptive paradigms, methods that anticipate and mitigate disruptions before they occur, and enhancements to emergency response. Approaches that enable health infrastructure to rapidly integrate information from new sensors; create decision support tools; adapt supply chains, manufacturing, and logistics; and better leverage the workforce during public health emergencies. Novel methods to engineer resilient tissues, microbiomes, and biophysical systems to combat disease or maintain health. Other novel approaches to enhance adaptability and reduce fragility within the health ecosystem.Proposals are expected to use innovative approaches to enable revolutionary advances in science, technology, systems, or methodology. Specifically excluded are proposals that represent an evolutionary or incremental advance in the state of the art or technology that has reached the clinical trial stage. Additionally, proposals directed towards policy changes, traditional education and training, or center coordination, formation, or development, and construction of physical infrastructure are outside the scope of the ARPA-H mission

The MMRDA mechanism is intended to fund the logical continuation of previously DOD-funded research or development efforts relevant to the above FY24 JWMRP Focus Areas with the highest potential to augment and accelerate medical product development and health care solutions for active-duty Service Members, their Families, Veterans, and/or the American public. Collaboration with DOD organizations is encouraged when this alliance would contribute to the success of the research effort, and any funds designated for DOD laboratories or activities should be identified in the application/proposal through submission of a Suggested Intragovernmental/Intramural Budget Form, Attachment 15. Applications/proposals from small businesses and/or partnerships with industry are also encouraged. The MMRDA mechanism supports a wide range of research projects, spanning late-stage preclinical studies, late-state technology development efforts, technology demonstration, and translational research. A Clinical Research or Clinical Trial Option is available to specifically support clinical research/observational studies, all phases of clinical trials/interventional studies, and/or correlative studies in support of the development of promising pharmaceutical or biologic candidates, medical devices, and technologies. Note: Applications/proposals submitted under this option will be required to submit additional relevant application/proposal materials.

This funding opportunity provides financial support for innovative breast cancer research projects aimed at preventing the disease, understanding its recurrence, or improving treatment, targeting both early-stage and more developed studies from a range of eligible organizations and researchers.

**AMENDED on DECEMBER 11 2023**: The latest revision is posted as Amendment 18. Potential applicants are strongly encouraged to review the Amendment in its entirety, as it updates several sections. Specifically, ATTACHMENT 1: SPECIFIC TOPICS now includes Basic Research Topics N1-N4, with white papers due by 11:59pm EST on 5 February 2024. White papers may not be considered if they are received after this deadline. In addition, submissions to the general thrust areas in accordance with the requirements detailed in the BAA are also welcome. ** Please note that all correspondence must be sent to the appropriate Agency contact identified in Section 7. Agency Contacts. **

This grant provides funding for collaborative clinical trials aimed at improving the diagnosis and treatment of health issues related to military toxic exposures, targeting researchers and institutions involved in this critical area of study.

**CYCLE 4 POSTED ON 10 APRIL 2024. SEE ATTACHED UPDATED ANNOUNCEMENT FOR SPECIFIC TOPICS OF INTEREST IN CYCLE 4 AND SUBMISSION INFORMATION** **CYCLE 3, ORIGINALLY POSTED ON 21 MARCH 2023, IS UPDATED TO INCLUDE A QUESTION AND ANSWER DOCUMENT AND TO UPDATE THE SUBMISSION DATE TO 5 MAY 2023 BY 1700 EASTERN TIME** **CYCLE 3 POSTED ON 21 MARCH 2023. SEE ATTACHED UPDATED ANNOUNCEMENT FOR SPECIFIC TOPICS OF INTEREST IN CYCLE 3 AND SUBMISSION INFORMATION** **CYCLE 2 POSTED ON 8 FEBRUARY 2021. SEE ATTACHED UPDATED ANNOUNCEMENT FOR SPECIFIC TOPICS OF INTEREST IN CYCLE 2 AND SUBMISSION INFORMATION** Purpose: Future Army forces will need to conduct cross-domain maneuver (CDM) and at times, operate semi-independently, disbursed, and while communications and infrastructure such as Global Positioning System (GPS) are disrupted or denied. Robotics and Autonomous Systems (RAS) will play a key role in expanding the operational reach, situational awareness, and effectiveness of maneuver forces in CDM. The Combat Capabilities Development Command (CCDC) Army Research Laboratory (ARL) is focused on developing fundamental understanding and informing the art-of-the-possible for warfighter concepts through research to greatly improve air and ground based autonomous vehicle perception, learning, reasoning, communication, navigation, and physical capabilities to augment and increase the freedom of maneuver in complex and contested environments. The Scalable, Adaptive, and Resilient Autonomy (SARA) program is focused on developing and experimentally accelerating emerging research in autonomous mobility and maneuverability, scalable heterogeneous and collaborative behaviors, and human agent teaming to realize adaptive and resilient Intelligent Systems that can reason about the environment, work in distributed and collaborative heterogeneous teams, and make op-tempo decisions to enable Autonomous Maneuver in complex and contested environments. In order to achieve this vision, advancements are needed in following: Novel methods for all-terrain ground and aerial maneuver to interact with and move through complex environments. Methods for scalable and heterogeneous collaborative behaviors in support of collaborative air and ground manned-unmanned teaming operations. Techniques for improved perception, decision-making, and adaptive behaviors for fully autonomous maneuver in contested environments. Methods, metrics, and tools to facilitate, simulate, and enable testing and evaluation of emerging approaches for intelligent and autonomous systems under Army relevant constraints and environments Experimental testbeds to develop and refine knowledge products to inform and transition technology to Army stakeholders.

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This funding opportunity provides financial support to various organizations and institutions to help prevent adversaries from exploiting advanced technologies and commercial facilities for military purposes, focusing on enhancing global partnerships and security measures.

The AARP Foundation is offering capacity building grants ranging from $10,000 to $100,000 for a period of 2 years to organizations that aim to enhance their resources and services to better connect adults aged 50 and above to health essentials programs, with a preference for projects serving communities facing systemic barriers and economic instability.

The Impact 100 Ozark grant program seeks to provide transformational grants to organizations serving eastern Christian County, Missouri. The foundation's mission is deeply aligned with this program, aiming to empower women to significantly improve community lives through generosity and by funding impactful grants. This strategic approach ensures that the grants have a lasting positive effect within the specified geographic area, reflecting Impact 100 Ozark's commitment to community betterment through focused financial support. The target beneficiaries for these grants are 501(c)3 organizations or other IRS-approved entities, including government entities, school districts, and churches, that specifically serve the eastern Christian County area. The primary impact goal is to fund significant initiatives that dramatically improve lives. While not explicitly stated as a "theory of change," the foundation's approach suggests that by empowering local organizations with substantial funding, they can address critical community needs and foster sustainable improvements. The program prioritizes proposals that avoid funding day-to-day operations, scholarships, or the start-up of new nonprofit agencies, indicating a focus on established organizations and projects with a clear, transformative scope. This ensures that the grants are directed towards initiatives that can create a significant, rather than incremental, impact. The available funding includes two grants totaling $49,000, with one grant of $35,000 and another of $14,000, underscoring the "significant grants" aspect of their mission. Expected outcomes and measurable results are inherent in the program's design, aiming for "lasting impact." While specific metrics are not detailed in the provided information, the emphasis on "transformational grants" implies a desire for substantial and demonstrable change within the community. The foundation's strategic priority is clearly to harness generosity to fund these impactful projects, thereby improving the lives of individuals and families in eastern Christian County.

The Projects for Organizations grant opportunity, offered by the Idaho Commission on the Arts, aims to support public projects and events by nonprofit organizations, informal arts groups applying through fiscal agents, and arts-in-education projects within schools and school districts. This grant aligns with the Commission's mission to foster arts and culture within Idaho by directly funding initiatives that engage the public and promote arts education. The program specifically targets organizations operating in Idaho for at least one year with a valid 501(c)(3) status or governmental units including schools. The primary beneficiaries of this grant are the citizens of Idaho, who benefit from increased access to public arts projects and events, and students within the state, who gain from enhanced arts-in-education programming. The impact goals include enriching community life through cultural offerings and fostering artistic development and appreciation. The grant prioritizes projects that compensate professional artists and meet specific eligibility criteria, ensuring a high standard of artistic endeavor and professional practice. Funding information indicates that grants are up to $1,100 and require a 1:1 match (cash or in-kind), funding up to 50% of projected expenses. This demonstrates a strategic priority to leverage additional resources and encourage community investment in arts projects. While specific measurable results beyond successful project completion and financial accountability are not explicitly detailed, the focus on public projects and arts-in-education implies expected outcomes such as increased community engagement in the arts and improved arts literacy among students. The Idaho Commission on the Arts' strategic priority, as reflected in this grant, is to provide accessible funding for a diverse range of artistic and cultural projects across all counties in Idaho. Their theory of change appears to be that by providing financial support and setting clear eligibility and project guidelines, they can empower local organizations and schools to deliver high-quality arts experiences, thereby enriching communities and fostering a vibrant arts ecosystem throughout the state. The requirement for final reports for past grants also indicates a commitment to accountability and continuous improvement within their funding programs.

This funding opportunity supports urban youth agricultural education and community development initiatives in Minnesota's urban and peri-urban areas, benefiting a range of organizations including nonprofits, schools, and local governments.

This program provides early-stage life science startups nationwide with free mentorship, networking, and resources to help them grow and prepare for investment opportunities.

The Small Rural Hospital Improvement Program (SHIP), overseen by the Minnesota Department of Health, aims to assist small rural hospitals in implementing value-based payment systems and improving health care quality. The program is supported by the U.S. Department of Health and Human Services through the Federal Office of Rural Health Policy. SHIP funding focuses on enabling hospitals to comply with Medicare program requirements, improve health care quality, and achieve financial sustainability. For the 2025 program year, the estimated maximum grant award for eligible hospitals is $13,832, distributed equally based on state allocations. The grant does not require matching funds and operates on an annual funding cycle, with the 2025 program year running from June 2025 to May 2026. The program supports non-federal, short-term general acute care hospitals with 49 or fewer beds, located in rural areas. Eligible entities include for-profit, nonprofit, and faith-based organizations, as well as tribal hospitals. Critical Access Hospitals automatically qualify under their rural designation. Applicants must disclose potential organizational changes, such as mergers, during the application process. Collaboration is encouraged, and hospitals may apply as networks or consortia. SHIP funding can be used for a variety of purposes, including purchasing hardware and software, providing training, and supporting efforts related to value-based purchasing, accountable care organizations, and payment bundling. Examples include implementing electronic health records, conducting quality improvement training, and enhancing interoperability systems. Certain expenses are ineligible, such as staff salaries, contractor fees without training components, and supplies for patient satisfaction. Applications must be submitted online via the Minnesota Department of Health’s Grants Portal by January 10, 2025, at 4:30 p.m. Central Time. Required materials include a completed application form, budget allocation, project descriptions, and disclosures. Current SHIP grantees must reapply to receive funding for the new cycle. An informational webinar will be held on December 17, 2024, to assist applicants, with materials available afterward. Selection criteria include compliance with submission requirements, alignment with SHIP goals, and detailed descriptions of planned activities. Grantees are required to submit mid-year and final reports to ensure accountability and secure payments. The state reserves the right to conduct monitoring visits and financial reconciliations for grants exceeding $50,000. Technical assistance is available from the Minnesota Department of Health. The program emphasizes compliance with affirmative action, nondiscrimination laws, and conflict-of-interest disclosures. Applications become public after the evaluation process, except for designated trade secrets. The program timeline includes specific deadlines for reporting and invoicing, with the final report due by July 2026. Grantees must ensure their projects align with the state and federal requirements outlined in the program guidelines.

This funding opportunity provides financial support for the construction and renovation of child care and early learning facilities in King County, prioritizing projects that serve low-income, BIPOC, and underserved communities.

This grant provides funding opportunities for a wide range of organizations, including universities and businesses, to advance manufacturing technologies, with a particular encouragement for participation from historically black colleges and universities and minority institutions.

This program provides financial support to small businesses in Lancaster for purchasing essential equipment to help create jobs and boost local economic growth.

This funding opportunity is designed to support early career researchers in heliophysics, enabling them to conduct innovative studies related to the Sun and its interactions with the Earth and space environment.

The PMGP was started in 1970 to support research in the field of fundamental measurement or the determination of fundamental constants, enabling the faculties at universities and colleges and laboratory researchers to conduct significant research in this area. By funding the research projects of eligible applicants through this program, NIST supports advances in fundamental measurement, the determination of fundamental constants, and fosters extramural collaboration with NIST scientists.

This grant provides financial support to individuals, artists, and community organizations in Worcester County to develop projects in the arts, humanities, and sciences that enhance the cultural landscape and benefit local residents.