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Grants for Nonprofits - Science and Technology

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Ideas Lab: Advancing Cell-Free Systems Toward Increased Range of Use-Inspired Applications
$3,750,000
National Science Foundation
Federal

Application Deadline

Sep 20, 2024

Date Added

Mar 2, 2024

The U.S. National Science Foundations Directorate for Technology, Innovation and Partnerships (TIP) is charged with accelerating use-inspiredand translationalresearch and development (R) to advance U.S. competitiveness in key technology focus areas. The Advancing Cell-Free Systems Toward Increased Range of Use-Inspired Applications (CFIRE) initiative will accelerate the adoption of cell-free systems, enable new applications of this technology and contribute to the growth of the U.S. bioeconomy. A nascent industry has formed around the ability to carry out biochemical processes, such as DNA transcription/translation, in cell-free in-vitro systems instead of in traditional cell-based in-vivo bio-reactors. This approach has a number of potential advantages, including rapid turn-around, distributed and highly retargetable manufacturing, high-fidelity instrumentation and control of the manufacturing environments without the constraints of biological growth and the interference caused by cell biomass and cell membranes during product purification. Furthermore, cell-free systems can produce products that are challenging to manufacture in cell-based cultures, such as those inherently toxic to cells or hydrocarbon products that are consumed by the cellular machinery. Despite these advantages, present-day cell-free manufacturing is significantly more expensive than cell-based methods and cell-free systems have a limited range of applications. CFIRE aims to: 1. Reduce the cost of cell-free systems; 2. Increase the range and capabilities of cell-free systems; and 3. Develop and demonstrate cost-effective use-inspired applications. CFIRE will address the key limitations of cell-free technology by identifying technical approaches that can enable ongoing cycles of improvement. The objective is to place cell-free technology on an exponential growth path in which reduced costs lead to increasing adoption which, in turn, generates the learning and investment required to further reduce costs. In order to keep the work focused and to stimulate increasing adoption, efforts funded through this initiative will focus on one or more specific use cases. CFIRE seeks significant breakthroughs that will accelerate the adoption of cell-free systems by: (a) Demonstrating the feasibility and advantages of cell-free systems through use-inspired applications with specific emphasis on applications beyond human therapeutics; (b) Creating infrastructure components, such as tools, protocols, kits, datasets, and characterization services that can readily be accessed by third parties; and (c) Investing in workforce components focused on the training of translational talent with the skills and passion to engage in use-driven cell-free applications. CFIRE will use the Ideas Lab process (see PAPPG Chapter II.F.6), starting with an intensive meeting that brings together multiple diverse perspectives. The primary objectives of this Ideas Lab workshop will be to: identify specific opportunities to significantly reduce the cost of cell-free systems; establish acceptable standards for the fidelity and reproducibility; expand the range of capabilities in order to facilitate broader adoption of the technology; and identify and prioritize use-driven applications beyond human therapeutics.

Science and Technology
Exclusive - see details
ROSES 2024: D.2 Astrophysics Data Analysis Program
$6,000,000
NASA-HQ (NASA Headquarters)
Federal

Application Deadline

May 16, 2024

Date Added

Feb 15, 2024

Please note that this program requests optional Notices of Intent, which are due via NSPIRES by March 28, 2024. See the full posting on NSPIRES for details. Proposers must retrieve the instructions document (zip file) associated with the application package for this opportunity as there is at least one required form that must be attached to the submitted proposal package. The National Aeronautics and Space Administration (NASA) Science Mission Directorate (SMD) released its annual omnibus Research Announcement (NRA), Research Opportunities in Space and Earth Sciences (ROSES) 2024 (OMB Approval Number 2700-0092, CFDA Number 43.001) on February 14, 2024. In this case "omnibus" means that this NRA has many individual program elements, each with its own due dates and topics. All together these cover the wide range of basic and applied supporting research and technology in space and Earth sciences supported by SMD. Awards will be made as grants, cooperative agreements, contracts, and inter- or intra-agency transfers, depending on the nature of the work proposed, the proposing organization, and/or program requirements. However, most extramural research awards deriving from ROSES will be grants, and many program elements of ROSES specifically exclude contracts, because contracts would not be appropriate for the nature of the work solicited. The typical period of performance for an award is three years, but some programs may allow up to five years and others specify shorter periods. In most cases, organizations of every type, Government and private, for profit and not-for-profit, domestic and foreign (with some caveats), may submit proposals without restriction on teaming arrangements. Tables listing the program elements and due dates (Tables 2 and 3), a table that provides a very top level summary of proposal contents (Table 1), and the full text of the ROSES-2024 "Summary of Solicitation", may all be found NSPIRES at http://solicitation.nasaprs.com/ROSES2024. This synopsis is associated with one of the individual program elements within ROSES, but this is a generic summary that is posted for all ROSES elements. For specific information on this particular program element download and read the PDF of the text of this program element by going to Tables 2 or 3 of this NRA at http://solicitation.nasaprs.com/ROSES2024table2 and http://solicitation.nasaprs.com/ROSES2024table3, respectively, click the title of the program element of interest, a hypertext link will take you to a page for that particular program element. On that page, on the right side under "Announcement Documents" the link on the bottom will be to the PDF of the text of the call for proposals. For example, if one were interested in The Lunar Data Analysis Program (NNH24ZDA001N-LDAP) one would follow the link to the NSPIRES page for that program element and then to read the text of the call one would click on C.8 Lunar Data Analysis Program (.pdf) to download the text of the call. If one wanted to set it into the context of the goals, objectives and know the default rules for all elements within Appendix C, the planetary science division, one might download and read C.1 Planetary Science Research Program Overview (.pdf) from that same page. While the letters and numbers are different for each element within ROSES (A.12, B.7, etc.) the basic configuration is always the same, e.g., the letter indicates the Science Division (A is Earth Science, B is Heliophysics etc.) and whatever the letter, #1 is always the division overview. Frequently asked questions for ROSES are posted at http://science.nasa.gov/researchers/sara/faqs. Questions concerning general ROSES-2024 policies and procedures may be directed to Max Bernstein, Lead for Research, Science Mission Directorate, at sara@nasa.gov, but technical questions concerning specific program elements should be directed to the point(s) of contact for that particular element, who may be found either at the end of the individual program element in the summary table of key information or on the web list of topics and points of contact at: http://science.nasa.gov/researchers/sara/program-officers-list. Not all program elements are known at the time of the release of ROSES. To be informed of new program elements or amendments to this NRA, proposers may subscribe to: (1) The SMD mailing lists (by logging in at http://nspires.nasaprs.com and checking the appropriate boxes under "Account Management" and "Email Subscriptions"), (2) The ROSES-2024 blog feed for amendments, clarifications, and corrections to at https://science.nasa.gov/researchers/solicitations/roses-2024/, and (3) The ROSES-2024 due date Google calendars (one for each science division). Instructions are at https://science.nasa.gov/researchers/sara/library-and-useful-links (link from the words due date calendar).

Science and Technology
Nonprofits
Flash Grant Cycle 3
$27,500
North Carolina Biotechnology Center (NCBiotech)
Private

Application Deadline

Mar 19, 2025

Date Added

May 17, 2024

This program provides quick funding to researchers at North Carolina universities and nonprofit institutes to develop innovative life sciences projects that show strong commercial potential.

Science and Technology
Public and State controlled institutions of higher education
Union County Tourism Grant 2025
$100,000
Union County Tourism
Local

Application Deadline

Not specified

Date Added

Nov 14, 2024

This funding opportunity supports events and projects that boost tourism in Union County, Ohio, targeting both nonprofit and for-profit organizations, as well as municipalities, to enhance the area's appeal and economic impact.

Business and Commerce
Nonprofits
DoD Toxic Exposures Investigator-Initiated Research Award
$770,000
U.S. Department of Defense (Dept. of the Army -- U.S.AMRAA)
Federal

Application Deadline

Oct 16, 2025

Date Added

Jun 6, 2025

This funding opportunity supports independent researchers in studying the prevention, diagnosis, and treatment of diseases related to military toxic exposures, benefiting Service Members, Veterans, and their families.

Science and Technology
City or township governments
Action Grants
$15,000
New Jersey Council for the Humanities
Private

Application Deadline

Apr 15, 2025

Date Added

Sep 20, 2024

This funding opportunity provides financial support for New Jersey-based nonprofit organizations and government entities to implement public humanities projects that engage local audiences through activities like exhibitions, oral history projects, and community programs.

Humanities
City or township governments
RFGA2024-017 Community Health Worker (CHW) Sustainability
$250,000
State of Arizona
State

Application Deadline

Jul 11, 2024

Date Added

May 24, 2024

The subrecipient shall access the current utilization of CHWs in the State of Arizona. The subrecipient shall use results to inform and develop a statewide CHW workforce development plan to expand CHW curricula, training delivery, career ladders, integration of CHWs, promotion of CHW voluntary certification, and/or sustainable payment mechanisms for CHW services. Financial Notes: Funds for the Clinical Health Worker (CHW) Sustainability come from the Centers for Disease Control and Prevention (CDC), A Strategic Approach to Advancing Health Equity for Priority Populations with or at Risk for Diabetes (Part A) CDC-RFA-DP-23-0020 grant (230020).

Workforce Development
City or township governments
Arts Pathways for Youth Success Grant 2026
$100,000
Tennessee Arts Commission
Private

Application Deadline

Not specified

Date Added

Nov 20, 2024

This program provides funding for out-of-school arts initiatives that help underserved youth develop essential skills for success in education and careers through artistic engagement.

Arts
Nonprofits
Byrne Justice Assistance Grants
$500,000
Washington State Department of Commerce
Private

Application Deadline

Sep 16, 2024

Date Added

Sep 4, 2024

The Byrne Justice Assistance Grant (JAG) Washington Innovation Fund is a program designed to enhance Washington state's criminal legal system by supporting innovative, sustainable, and data-driven practices. Its overarching goals are to improve community safety, foster collaboration among various sectors, and provide support to victims and individuals involved in the criminal legal system. This aligns with a foundational mission of creating a fair and equitable criminal legal system in Washington that prioritizes these critical areas. The program draws on the Edward Byrne Memorial JAG program, a significant federal source of criminal justice funding, administered by the Bureau of Justice Assistance (BJA), which provides essential resources to state and local jurisdictions for system improvement and community advancement. The target beneficiaries of the JAG Innovation Fund include local governments and private community-based or non-profit agencies that are working to improve the criminal legal system. The program aims to impact community safety directly, enhance support for victims, and strengthen cross-sector collaboration and collective accountability within the system. Ultimately, the expected outcomes include the implementation of more effective and data-informed stewardship of criminal legal system resources, leading to a more just and safer Washington. The JAG Innovation Fund focuses on several key priorities for funding, including organizational or program capacity building, supporting new ideas, projects, or promising practices, enhancing system and community collaborations, and expanding or supplementing existing programs or practices. The program identifies nine specific Purpose Areas to allow for diverse and flexible criminal legal system improvement projects. These areas range from Planning, Evaluation and Technology Improvement to Crime Victim Programming, Support and Advocacy, Community Safety Enhancement, and Corrections, Community Corrections and Re-Entry, among others. Approximately $1,000,000 of JAG funding is dedicated to the Innovation Fund each award cycle, with individual project awards supporting proposals up to $150,000. The funding period for projects is from November 1, 2024, to December 31, 2025. To ensure accountability and community relevance, non-governmental applicants must provide one or more letters of support from a local government unit in the project's jurisdiction, explaining the proposed program's benefits to the local government agency and jurisdiction. This requirement underscores the program's strategic priority of fostering robust community and governmental partnerships as a theory of change for sustainable criminal legal system improvements.

Law Justice and Legal Services
County governments
Community Food Services
$50,000
City of San Leandro
Local

Application Deadline

Not specified

Date Added

Oct 7, 2024

This funding provides financial support to local nonprofit organizations in San Leandro that offer food services and assistance to low-income residents.

Food and Nutrition
City or township governments
DoD, Melanoma, Survivorship Research Award
$2,300,000
U.S. Department of Defense (Dept. of the Army -- U.S.AMRAA)
Federal

Application Deadline

Aug 26, 2024

Date Added

May 9, 2024

The key aspects of this award are: Impact: The SRA is intended to support research designed to have a major impact on the health and well-being of melanoma survivors, their families, and/or caregivers. Impactful research will accelerate the movement of promising ideas into clinical applications or other real-world applications and advance the field of melanoma-specific quality of life and survivorship. Study Design: Applications should clearly articulate and justify the chosen study design. Studies proposing retrospective analyses or prospective enrollment should clearly describe the architecture of the study (e.g., descriptive, correlational, field experimental, meta-analyses) and the study population(s). The study population(s) should be representative of the people who are anticipated to benefit from the research. If applicable, questionnaires should be described in sufficient detail to justify interpretation of potential results. Melanoma Consumer Collaboration: For the purposes of the SRA, a melanoma consumer is defined as a melanoma survivor, family member, and/or caregiver who can provide lived experience expertise to the research project team. Applicants to the SRA are required to establish a collaborative research approach with the melanoma consumer community to maximize the impact and translatability of the research for the benefit of the intended melanoma community(ies). The research team must include at least one melanoma consumer or a melanoma-community supporting organization who will be integral to the planning, execution, and implementation of the proposed research. The role of the melanoma consumer collaborator(s) should include providing objective input on the research question being addressed; the study design, execution, and evaluation; and the potential impact of the research outcomes on the health and well-being of melanoma survivors, their families, and/or their caregivers. The melanoma consumer collaborator(s) should be active participants and integrated into the research team; their participation should not be limited only to passive activities (e.g., attending seminars or quarterly team meetings). Additional information and resources for establishing a collaborative research approach with the melanoma consumer community is provided below.Other Important Considerations:Collaborative Research Approaches: Collaborative research approaches create partnerships between scientific researchers and, for the purposes of the SRA, melanoma consumers to create knowledge useable by both sets of stakeholders. Recognizing the strengths of each partner, scientific researchers and melanoma consumers collaborate and contribute equitably on all aspects of the project, which may include needs assessment, planning, research intervention design, implementation, evaluation, and dissemination. Collaborative research approaches feature shared responsibility and ownership for the research project to ensure non-tokenistic involvement of the melanoma consumers within the research team. Research results are jointly interpreted, disseminated, and fed back to affected communities and in some instances may be translated into interventions or policy.Collaborative relationships with the melanoma consumer community may be established through integrating melanoma consumers and/or melanoma-community supporting organizations into research teams as co-researchers, advisors, and/or consultants. Examples for implementing collaborative research approaches are listed below, but each research team may pursue other options as appropriate for the proposed research: The research team includes at least one melanoma consumer who will provide advice and consultation throughout the planning and implementation of the research project. The consumer(s) should be able to speak to the needs of the melanoma consumer community, not just speak to their own personal experiences. The research team establishes partnerships with at least one community-supporting organization that provides advice and consultation throughout the planning and implementation of the research project. Community-supporting organizations may include advocacy groups or other formal organizational stakeholders that can speak to the needs of the melanoma consumer community. The research team assembles a melanoma consumer community advisory board. The advisory board may include melanoma consumers, a coalition of community-supporting organizations, or any combination thereof that provides advice and consultation throughout the planning and implementation of the overall program and/or individual research projects.

Science and Technology
Nonprofits
Annual Program Statement_UAE_2025
$200,000
U.S. Department of State (U.S. Mission to United Arab Emirates)
Federal

Application Deadline

Aug 18, 2025

Date Added

Jun 19, 2025

This funding opportunity supports not-for-profit organizations and educational institutions in the UAE to develop programs that strengthen U.S.-UAE relations through cultural events, space exploration initiatives, and entrepreneurship activities.

International Development
Nonprofits
Cultural STAR Special Project Grant
$796,366
City of Saint Paul
Local

Application Deadline

May 15, 2024

Date Added

May 3, 2024

The Special Project grants, offered by the City of Saint Paul through its Cultural STAR fund, aim to support quality arts activities across all disciplines within the city's geographic boundaries. This initiative is deeply aligned with the fund's overarching mission to promote cultural vitality and economic growth, particularly within the downtown Cultural District, by strengthening the arts and culture community. The grants are designed to support projects that contribute to a vibrant cultural landscape, ultimately enhancing the quality of life for residents and attracting visitors, thereby fostering economic development. Target beneficiaries for these grants include nonprofit arts and cultural organizations located within the City of Saint Paul, as well as informal arts-focused groups, individuals, and one-time arts projects that partner with eligible nonprofits. Businesses in the Cultural District are also eligible for projects that enhance visitor enjoyment. The impact goals are centered on building and diversifying audiences, promoting a broad range of cultural offerings, producing long-term cultural impact, and leveraging additional financial support for the arts. The Cultural STAR Program prioritizes projects and programs that attract audiences, develop and improve cultural facilities, and build the capacity of artists and cultural organizations. A significant focus is placed on the Cultural District of downtown Saint Paul, with at least 80% of funds allocated to nonprofit organizations within this targeted area. The remaining 20% can support businesses in the Cultural District or nonprofit organizations located elsewhere in Saint Paul. This geographic focus underscores the strategic priority of revitalizing and enriching the downtown cultural hub. Expected outcomes include increased audience engagement with diverse cultural offerings, enhanced and accessible cultural facilities, and strengthened organizational capacity within the arts and culture sector. Measurable results could include metrics related to audience attendance, the number and variety of cultural events, improvements in cultural infrastructure, and the ability of organizations to secure additional funding. The Cultural STAR fund's theory of change is that by investing in these areas, it will lead to sustained cultural vitality and economic growth, creating a dynamic and engaging environment for both residents and tourists.

Arts
City or township governments
Room Tax Grant
$100,000
County of Chemung
Local

Application Deadline

Not specified

Date Added

Feb 27, 2025

This funding opportunity is designed for non-profit organizations in Chemung County to promote tourism through events and promotional initiatives that attract visitors and boost local economic activity.

Business and Commerce
Nonprofits
Firearms and Archery Range Recreation Program
$150,000
Washington State Recreation and Conservation Office
State

Application Deadline

Oct 31, 2024

Date Added

Aug 28, 2024

This funding opportunity provides financial support to various organizations, including cities, counties, and nonprofit shooting groups, for the acquisition, development, and renovation of firearm and archery training facilities to improve public access and safety.

Recreation
City or township governments
2024 Arkansas Computer and Electronic Waste Recycling Grants
Contact for amount
Arkansas Department of Environmental Quality
State

Application Deadline

Jun 1, 2024

Date Added

Apr 22, 2024

The Arkansas Department of Environmental Quality runs an annual Electronic Waste Grants. This initiative aims to address electronic waste through projects focused on collection, transportation, processing, recycling, demanufacturing, and innovative approaches to disposal. Eligible projects are evaluated based on the sustainability and impact of their e-waste recovery efforts, including the minimization of e-waste volumes, job creation in Arkansas, and the effectiveness of investment in the projects. Eligible applicants include a wide range of entities within Arkansas, such as private industries, educational institutions, governmental bodies, non-profits, and regional solid waste management boards. This program operates on a reimbursement basis. Grant renewed every year. Grant Annual opening/closing deadline: January 1st to June 1st

Environment
Nonprofits
The Calvin K. Kazanjian Economics Foundation Grant 2025
Contact for amount
The Calvin K. Kazanjian Economics Foundation
Private

Application Deadline

Sep 10, 2025

Date Added

Aug 15, 2025

This grant provides funding to nonprofit organizations in the U.S. that develop innovative economic education programs, particularly those utilizing artificial intelligence to improve learning outcomes and engagement.

Education
Nonprofits
Rural Arts Facilities Fund 2026
$500,000
Tennessee Arts Commission
Private

Application Deadline

Not specified

Date Added

Nov 20, 2024

This program provides funding to rural communities in Tennessee for building or improving arts and cultural facilities to boost local economies and enhance quality of life through arts programming.

Arts
County governments
Mohawk Valley Historic Revitalization Grant Program in New York
$100,000
Erie Canalway National Heritage Corridor
Private

Application Deadline

Oct 31, 2024

Date Added

Jun 5, 2024

This grant provides funding for the rehabilitation of historic properties in small rural communities along the Erie Canal in New York, aiming to enhance local tourism and economic development.

Workforce Development
Nonprofits
HRER45 Tributary Restoration and Resiliency
$800,000
Dept of Environ Conservtion
State

Application Deadline

Not specified

Date Added

Oct 3, 2024

This grant provides funding to municipalities, non-profits, and educational institutions in New York to restore and improve the health of tributaries in the Hudson River Estuary watershed, enhancing habitats and community resilience to flooding.

Environment
City or township governments