Grants for Nonprofits - Science and Technology

This funding opportunity provides financial support to nonprofit arts organizations in New Hanover County to enhance community arts experiences through operational and programming initiatives.

This funding opportunity provides financial support to public schools and nonprofit organizations in Durham County for innovative educational programs that promote equity and enhance college or career readiness for young people.

This funding provides financial support to social service organizations in Carlsbad to improve housing and services for low-income residents and those with special needs.

The **Sisters of Charity Foundation of South Carolina** offers **Immediate Needs Grants** to support organizations that address the most pressing and basic needs of individuals and families experiencing poverty across South Carolina. These grants are intended to help nonprofits provide direct services and essential resources that contribute to stability, dignity, and improved quality of life. By funding programs that deliver immediate relief and empower long-term self-sufficiency, the foundation continues its mission of reducing poverty and fostering compassion-driven community change throughout the state. Grants in this category are awarded to organizations delivering programs that meet needs related to **life and health**, **education and skills**, and **access and participation**. Examples of eligible initiatives include programs offering food assistance, mental health support, healthcare access, housing, literacy education, vocational training, affordable childcare, or transportation services. Each grant provides **$5,000** in funding, and **Cycle II Immediate Needs Grants** specifically target organizations with annual operating budgets of **$500,000 or more**, ensuring that established service providers have resources to meet urgent community challenges. The foundation evaluates applicants based on their demonstrated impact, community engagement, and accountability. Eligible organizations must identify and fill gaps in local resources, gather and apply participant feedback, and define clear measures of program success. Funded programs must have a direct and immediate effect on people’s daily lives, improving access to essential services and strengthening participants’ ability to thrive despite economic hardship. The grants aim to support both the continuity and expansion of programs that have proven effectiveness in addressing the complex realities of poverty. Eligibility is limited to organizations operating **within South Carolina** that have been established for at least one year. The foundation does not fund individuals, capital campaigns, scholarships, or organizations whose missions do not directly address poverty. Instead, it focuses on nonprofits that demonstrate strong community relationships, responsiveness to local needs, and an ability to deliver measurable outcomes tied to human well-being. Through the Immediate Needs Grant program, the Sisters of Charity Foundation reaffirms its enduring commitment to serving South Carolinians with compassion and equity. By supporting programs that meet basic needs while fostering education, access, and health, the foundation works toward its broader vision—a South Carolina where all individuals have the opportunity to live with dignity, security, and hope.

This grant provides financial support to local nonprofit organizations in Volusia and Flagler Counties to enhance programs focused on education, financial stability, and health for community improvement.

The objective of this research proposal is to develop physiologically based pharmacokinetic (PBPK) model-based mechanistic in vitro in vivo correlations (IVIVCs) for two major types of long acting injectables (LAIs) such as crystalline suspensions and polymer-based implants by considering their distinct characteristics. The goal of the project is to develop a bottom-up mechanistic PBPK model for these two LAI categories by accounting for the influence of critical formulation attributes of each LAI drug product type to predict its in vivo release mechanism. The model formulation parameters and relevant physiology should be informed with suitable in vitro and in vivo experiments. A suitable preclinical animal model can be used to validate the PBPK model based IVIVCs for both LAI suspensions and polymer based implants. The use of PBPK modelling provides a unique opportunity to understand how the physicochemical properties of drug molecules/polymer, implant specific properties, critical formulation attributes, and physiology, among other things, influence the in vivo release mechanisms of LAI drug products and their disposition characteristics. Moreover, once developed, a mechanistic PBPK model can help to define the 'safe space' for critical formulation attributes relevant to the reference listed drug (RLD) product, explain sources of PK variability and extrapolate predictions to human subjects by leveraging animal model data and by accounting for species-specific physiological differences.

This grant provides funding for researchers and organizations to develop and utilize artificial intelligence and machine learning techniques on heliophysics data, enhancing our understanding of solar and space phenomena.

The Onion Foundation aims to connect Maine residents with arts experiences, both as audience members and creators, fostering opportunities for expression, learning, and inspiration. This aligns directly with the foundation's mission, which recognizes the arts' crucial role in creativity, cultural exchange, intellectual development, joy, compassion, and human connection. The foundation seeks to support a vibrant arts sector in Maine, ensuring that the arts are accessible and beneficial to the state's population. The target beneficiaries of this grant program are Maine residents, with a focus on increasing access to arts education, supporting public engagement in arts programs, and building the capacity of Maine's arts sector. The impact goals are to enhance intellectual development, foster joy and compassion, and strengthen feelings of connection among individuals through artistic engagement. The foundation prioritizes organizations that are 501(c)3 public charities, fiscally sponsored projects, public education institutions, or Maine governmental units, with work based in Maine and benefiting its people. The program offers two types of grants: general operating and project support. General operating grants provide unrestricted funds for organizations whose activities align with the foundation's strategies, offering multi-year support of up to $20,000 per year for organizations with annual budgets over $50,000, and up to $7,500 per year for those under $50,000. Project support grants fund specific activities or programs, also with multi-year options and similar funding tiers based on project budgets. The expected outcomes include a more engaged public in Maine arts, a stronger arts education infrastructure, and a more robust overall arts sector in the state. The Onion Foundation's strategic priorities are clearly outlined in its three guiding strategies for the arts program: Strategy I: Increase Access to Arts Education in Maine, Strategy II: Support Public Engagement in Maine Arts Programs, and Strategy III: Build The Capacity of Maine’s Arts Sector. The theory of change implicitly suggests that by funding these areas, the foundation will achieve its broader mission of connecting Maine residents to arts experiences, leading to expression, learning, and inspiration, and ultimately fostering a more creative, compassionate, and connected society. Measurable results would likely include increased participation rates in arts programs, growth in arts education initiatives, and the sustained health and development of arts organizations in Maine.

TheMacrosystems Biology and NEON-Enabled Science (MSB-NES): Research on Biological Systems at Regional to Continental Scalesprogram will support quantitative, interdisciplinary, systems-oriented research on biosphere processes and their complex interactions with climate, land use, and changes in species distributionatregional to continental scales as well as training activities to broaden participation of researchers in Macrosystems Biology and NEON-EnabledScience. MSB-NES projects that use data and/or resources fromthe National Ecological Observatory Network(NEON) are encouraged. Substantive NEON-enabled projects rely on data and/or samples collected by NEON and/or co-locate research activities at NEON sites. Projects may develop tools that will explicitly enhance the processing, use, and/or analysis of NEON data or collections, in the context of addressing a specific research question or hypothesis. However, proposals primarily focused on tool development that can be used for a broad class of research questions or for topics that meet the needs of a community of researchers should be directed toward the Infrastructure Innovation for Biological Research (Innovation) or Infrastructure Capacity for Biological Research (Capacity) programs in the Division of Biological Infrastructure.

The National Academy of Sciences Gulf Research Program is investing $50 million in the Gulf Futures Challenge to fund projects addressing critical challenges in the Gulf region. The Challenge aims to discover and promote innovative and transformative solutions by leveraging the talent and knowledge of the Gulf's people. The competition focuses on three main areas: energy transition, environmental change along the coast, and healthy and resilient communities. Up to ten finalists will receive up to $1 million in project development support, with two finalists awarded $20 million each to implement their solutions. Eligible applicants include nonprofits, state, local, and tribal governments, and academic institutions from Alabama, Florida, Louisiana, Mississippi, or Texas, with projects located within 100 miles of the Gulf coastline. The registration deadline is August 20, 2024, and the application deadline is September 20, 2024.

The Foothills Community Partnership Charitable Grant Fund, administered by the Community Foundation of Northeast Alabama, offers grants ranging from $1,000 to $10,000 for a duration of one year. This program is specifically designed to support 501(c)(3) qualified public charities operating within Calhoun County, Alabama. The core mission of this fund is to benefit and enhance the sustainability of services provided by non-profit organizations that address critical human care issues within the county. This aligns directly with the Foundation's broader strategic goal of fostering community well-being and supporting vital local services. The primary beneficiaries of this grant program are non-profit organizations serving Calhoun County that focus on human care issues. The overarching impact goal is to strengthen these organizations, enabling them to deliver more effective and sustainable services to the community. By providing financial support, the fund aims to help these organizations achieve their objectives and improve the quality of life for residents in Calhoun County. The fund's priorities and focus areas are clearly defined: Education, Community and economic development, and Safety and wellness. Programs and projects that address these specific community issues are given precedence. This targeted approach ensures that the grants contribute to strategic areas identified as crucial for the growth and stability of the community. Expected outcomes include a strengthened non-profit sector in Calhoun County, leading to improved access to essential human care services. Measurable results could involve an increased number of individuals benefiting from educational programs, enhanced economic opportunities, or a reduction in safety and wellness concerns within the community, all directly supported by the funded projects. The Foundation's theory of change posits that by strategically investing in these key areas through local non-profits, it can foster a more resilient, educated, and healthy community in Calhoun County.

The Florida Department of Health's Sickle Cell Disease Research and Treatment Grant Program aims to enhance the quality and accessibility of healthcare services for individuals living with sickle cell disease (SCD) in Florida. This initiative also seeks to advance data collection and analysis to support SCD research. The program's mission is directly aligned with the department's public health goals, focusing on improving health outcomes for a vulnerable population through both direct care and scientific inquiry. The primary beneficiaries of this grant program are persons living with sickle cell disease in Florida, along with community-based sickle cell disease medical treatment and research centers operating within the state. The impact goals are to improve healthcare services and foster research that can lead to better treatments and understanding of SCD. This involves supporting existing centers of excellence and developing new ones, ultimately creating a more robust and accessible healthcare infrastructure for SCD patients. The program has two key priority areas: sickle cell disease workforce development and education, and sickle cell disease treatment centers of excellence. These priorities are designed to address both the human capital and infrastructure needs within the SCD care landscape. The grant funds, totaling up to $10 million, can be utilized for a variety of expenses, including personnel, facility upgrades, technology acquisition, and contractual services, all aimed at bolstering these priority areas. Expected outcomes include improved health service utilization, better patient outcomes, and a stronger network of SCD treatment centers across Florida. Projects are required to include impact evaluation plans to measure these changes. The program emphasizes the importance of proposals demonstrating how an applicant's strategic priorities integrate facility enhancement or the creation of new centers, as well as showcasing the organization's experience in securing and managing funding. This ensures that projects are not only well-conceived but also sustainable and capable of delivering measurable results in line with the department's objectives.

The UpPrize Social Innovation Challenge, powered by Innovation Works and funded by the BNY Mellon Foundation of Southwestern Pennsylvania, is an annual competition designed to foster entrepreneurship with a lasting community impact in Southwestern Pennsylvania. This initiative creates cross-sector partnerships to tackle pressing community problems, aligning with a broader mission to promote social innovation through investment, grants, and educational assistance. Since its inception in 2015, the UpPrize Challenge has allocated over $3.1 million to local nonprofits, entrepreneurs, and other participants, demonstrating a commitment to empowering community-driven solutions. The primary beneficiaries of this challenge are nonprofits, businesses, and individuals who are based in and whose startup's impact is within one of the following Pennsylvania counties: Allegheny, Armstrong, Beaver, Butler, Fayette, Greene, Indiana, Lawrence, Washington, or Westmoreland. The program specifically targets those who are 18 years or older and have not received $50,000 or more in previous UpPrize cycles. The core impact goal is to launch or expand startups that leverage technology to address social inequities, thereby creating a meaningful and lasting community impact in Southwestern Pennsylvania. The program's priorities and focus areas revolve around technology-driven solutions to social inequities. This is evidenced by the prize structure, which offers combined prize monies and accelerator assistance to the top three finalists to facilitate the launch or expansion of such startups. The challenge encourages innovation and entrepreneurship, particularly in areas that can demonstrate tangible benefits to the community through the application of new technologies and creative problem-solving. Expected outcomes include the successful launch or expansion of promising startups, leading to measurable improvements in social equity within the targeted counties. The challenge's structure, which awards significant prize money ($125,000 for first place, $100,000 for second, and $75,000 for third), incentivizes the development of impactful solutions. These investments are intended to translate into direct community benefits, fostering a more equitable and innovative environment in Southwestern Pennsylvania through the practical application of entrepreneurial endeavors.

This grant provides funding for researchers and organizations to conduct laboratory analysis of samples returned from space missions, supporting advancements in space and Earth sciences.

This program provides funding for early-career ocean scientists to conduct research, promote diversity in STEM, and engage in professional development through mentorship and collaboration at U.S.-based host organizations.

The Virginia Department of Criminal Justice Services (DCJS) is offering grant funds through its Combatting Hate Crimes Grant Program. This program aims to minimize bias-motivated incidents by providing competitive grants to local governments that have established partnerships with eligible non-profit, 501(c)3 institutions and organizations. These organizations are either current targets or at risk of being targets of hate crimes based on race, religious conviction, color, gender, disability, gender identity, sexual orientation, or national origin. The broader mission of this initiative aligns with public safety and social justice, seeking to protect vulnerable communities and promote an inclusive environment free from bias-motivated violence. The primary beneficiaries of this program are local governments and their partner non-profit, 501(c)3 institutions, and similarly situated organizations within their jurisdictions. These organizations are at risk for targeted, bias-motivated violence. The impact goal is to reduce the occurrence of hate crimes by strengthening the security and resilience of these at-risk entities. Expected outcomes include enhanced physical and cybersecurity, improved staff preparedness to respond to incidents, and a decrease in vulnerabilities identified through threat assessments. The program strategically prioritizes localities that demonstrate a proactive approach to risk mitigation, specifically those that have conducted threat assessments with local crime prevention officers. The program's focus is on funding projects that enhance security and preparedness against hate crimes. This includes support for target hardening activities, critical technology and infrastructure, and security and monitoring equipment. Additionally, funds can be used for contractual security services, such as on-site security, cybersecurity activities, and inspection and screening systems. Training is also a key priority, encompassing security-related training for employed and volunteer staff, response to serious incidents, and terrorism awareness. Personnel funding is available for part-time staff dedicated to performing security assessments for non-profit organizations. The grant duration is a twelve-month period, from January 1, 2025, to December 31, 2025. The total funding available for the Combatting Hate Crimes Grant Program for the FY2025 fiscal year is $3,500,000, with a maximum request of $150,000 per locality. Success will be measured by the implementation of approved security enhancements, documented training completion, and the capacity building of non-profit organizations to identify and address vulnerabilities. The program's theory of change posits that by providing resources for enhanced security, training, and threat assessment, at-risk organizations will become less susceptible to bias-motivated violence, thereby contributing to a safer community for all.

The City of San Carlos is offering a Childcare Grant Program, providing funding between $10,000 to $100,000 for local childcare centers, family childcare homes, and non-profit centers to fund capital improvement projects aimed at increasing childcare spaces, particularly for infants and children with special needs, with applications due by October 18, 2024.

This funding opportunity provides financial support for organizations to create a strategic plan aimed at achieving carbon neutrality in the District of Columbia by 2040, with a focus on promoting equity for communities most affected by climate change.

This grant provides funding for projects that conserve and restore grasslands and wildlife in the Southern Great Plains, particularly benefiting rural communities and enhancing climate resilience.

This initiative seeks input from energy stakeholders to identify and develop large-scale electric grid projects that can meet the increasing energy demands of industries like data centers and advanced manufacturing.