Grants for Nonprofits - Science and Technology

The FY24 Transformative Breast Cancer Consortium Award is designed to support collaborations and ideas that will transform the lives of individuals with, and/or at risk for, breast cancer and will significantly accelerate progress toward ending breast cancer. Applicants must bring together different perspectives to develop new paradigms that will solve fundamental yet overarching problems in breast cancer. This award requires a team-based approach by a consortium of exceptional researchers and advocates, whose collaborative efforts will make a transformative impact in breast cancer. The transformation intended by the consortium must be in peoples lives, and not in the healthcare or research system.This funding opportunity is a separate mechanism from the Transformative Breast Cancer Consortium Development Award, which is intended to provide successful applicants the time and resources needed to bring investigators and breast cancer advocates together to establish a consortium framework and conduct preliminary research to support application to a future, full Transformative Breast Cancer Consortium Award (pending availability of funds). For FY24, investigators may be named as Consortium Director on an application submitted to either (but not both) of these mechanisms. It is not necessary to receive a development award in order to apply for the current funding opportunity or anticipated full consortium awards in the future. Detailed information on the FY24 Transformative Breast Cancer Consortium Development Award is available under a separate program announcement (HT942524BCRPTBCCDA).For the FY24 Transformative Breast Cancer Consortium Award, the consortium should have at least four, but no more than five, project teams, each investigating different projects under a central hypothesis. No more than two project teams may be based at one institution. Each teams work must be integrated within the consortium so that every component is working toward the consortiums central hypothesis. Note: This award is not intended to replace, supplement, duplicate, or compete with other collaborative research efforts, such as the National Cancer Institute (NCI) Specialized Programs of Research Excellence (SPOREs), and it should not represent a collection of related Program Project grants or subprojects.The proposed consortiums overall work is expected to be innovative. In addition, the Transformative Breast Cancer Consortium Award will include funds for seed projects to pursue brand-new, high-risk/high-reward concepts that arise from the work, during the award period.DOD FY24 Transformative Breast Cancer Consortium Award 5The Breast Cancer Landscape describes the reality of breast cancer and identifies overarching challenges to progress the field. Research funded under this award mechanism should result in answers that will fundamentally and significantly transform and disrupt the present landscape.Applications submitted to the Transformative Breast Cancer Consortium Award must include the following: Research that includes truly innovative and brand-new, paradigm-shifting work in breast cancer that will address vital issues in a unique way. The issues may be one (or more) of the FY24 BCRP Overarching Challenges or, with justification, may be a different issue that meets the intent of the award mechanism and addresses the mission of ending breast cancer. If the application identifies a different fundamental issue, it must be coupled with at least one of the FY24 BCRP Overarching Challenges. Research that includes different disciplines that come together to address ending breast cancer with an ecologic approach. The consortiums proposed research must look at all aspects of the disease and bring together these different perspectives into one overarching plan for a deep, definitive dive into the FY24 BCRP Overarching Challenge(s) or other fundamental issue identified in the application. The plan also should include issues related to the hypothesis that have not been previously addressed or answered. A plan that describes in detail the integration across the consortium in all aspects, including administration, logistics, and substance. Applications must describe the substantive integration across and among teams that are necessary for the work. The required communication plan and administrative management plan will not suffice to show integration, nor will identifying individual team members who will cross teams. A detailed explanation of the substantive research processes that will be integrated is required.Synergistic, highly integrated, multidisciplinary, and multi-institutional research teams of leading scientists, clinicians, and consumer advocates must be assembled into a consortium to address a major problem in a way that could not be accomplished by a single investigator or group. While the project teams are made up of different groups, each with its own Principal Investigator (PI), the teams must be working on the major problem identified in the Transformative Breast Cancer Consortium Award application and under the leadership of the Consortium Director. The research proposed in Transformative Breast Cancer Consortium Award applications may include phase 1 clinical trials and collaborations with pharmaceutical or biotechnology industry scientists and/or companies, as appropriate. However, a clinical trial is not required, and the primary thrust of the application should not be a clinical trial.Although not all-inclusive, applications that propose the following as the primary effort(s) or central hypothesis of the consortium will not meet the intent of this award mechanism: NCI Program Project or SPORE grants or applications Conducting drug screens or testing a cocktail of therapeutics Targeting a single gene or protein Developing a new derivative or formulation of an old drug Conducting genomic landscape mapping analyses Seeking to improve existing technologies (e.g., mammography or magnetic resonance imaging screening)All applications submitted to the Transformative Breast Cancer Consortium Award must address the following key features:1. IMPACTDemonstrate potential to transform or improve the lives of individuals with, and/or at risk for, breast cancer. The time to the final impact may vary, but the outcomes of the effort must be transformative and significantly advance the BCRPs mission of ending breast cancer. A clear and compelling presentation of how the effort will be transformative for individuals with, and/or at risk for, breast cancer must be provided. Applications proposing research that represents an incremental advance in breast cancer do not meet the intent of this award mechanism.2. INNOVATIONPursue innovative, high-risk/high-reward research that has the potential to change existing paradigms, or develop new paradigms. Innovative research may introduce a new paradigm, look at existing problems from new perspectives, or exhibit other highly creative qualities. In addition to the requirement that the consortiums overall research be innovative, applications must describe a plan to support the pursuit of innovative concepts through seed projects, i.e., the development of new concepts that emerge during the course of the award. These seed projects should enable the research team to explore new avenues of high-risk/high-reward ideas that were not part of the original application, but that develop during the project and are within the scope of the overall vision of the research. A portion of the total direct budget costs (no more than 5%) must be reserved to support the seed projects, and these funds may not be used for equipment or travel.3. CONSORTIUMIntegrate project teams consisting of preeminent investigators and advocates from appropriate disciplines and institutions. Applications should include a robust consortium of researchers with the combined backgrounds and breast cancer-related expertise to enable successful conduct of the proposed research. Emphasis must be placed on integrating the most highly qualified investigators and advocates to focus on the research problem, regardless of their location. These investigators must include highly accomplished scientists, clinicians, and promising young investigators in the targeted areas of research who collectively represent the best team to solve the problem(s) identified. The proposed research effort should be broad enough to require a multidisciplinary approach that is reflected in the composition of the consortium team. Inclusion of scientists from nontraditional disciplines is encouraged.The award mechanism is structured with a Consortium Director and at least three, but no more than four, Project Team PIs representing at least two institutions. The Consortium Director is responsible for the day-to-day management of the consortium, as well as for leading their own project team. The Consortium Director, together with the Project Team PIs, are jointly responsible for leading and executing the proposed research projects that are integrated into a central hypothesis and will result in answers that will fundamentally and significantly transform and disrupt the present breast cancer landscape. Please see the top of this section, Section II.B, Award Information, for more details.Incorporate breast cancer consumer advocates into every aspect of the proposed consortiums activities. Applications are required to include consumer advocate involvement. The consortium team must include at least one breast cancer consumer advocate per project team. The consumer advocates are expected to represent the perspective of the patient population(s) that are most relevant to the consortiums proposed research. Breast cancer consumer advocates must have an active role in every aspect of the proposed consortiums work including consortium conception and design, ongoing discussion, decisions and oversight, program evaluation, and dissemination of information to the public. Consumer advocates must be integrated into and play an active role in the leadership and decision-making committees for the consortium at each participating institution. Examples of appropriate integration include membership on the advisory board(s) and steering committee(s), participation in each project team, and attendance at all consortium-related meetings. As lay representatives, the consumer advocates must be individuals who have been diagnosed with breast cancer, they should be part of a breast cancer advocacy organization, and their role in the project should be independent of their employment. They cannot be employees of any of the institutions participating in the application. They must have a high level of familiarity and training involving science and current issues in breast cancer research.4. INTEGRATIONProvide a plan that describes in detail the integration across the consortium in all aspects, including administration, logistics, and substance. Applications must demonstrate the substantive integration across and among teams that are necessary for the work. The integration plan must provide a detailed explanation of the substantive research processes that will be integrated.5. IMPLEMENTATIONProvide a strategy for implementation. Projects must demonstrate solid scientific rationale, and applications must include published and/or preliminary data that support the feasibility of their hypotheses and/or approaches. The application must include a detailed research management plan that identifies critical milestones, outlines the innovations and technical solutions that will be implemented to accomplish the milestones, and explains how these solutions will ultimately be translated to individuals with, and/or at risk for, breast cancer. It is expected that the proposed plan will present an exceptional level of innovation and creativity.Accelerate research progress through communication. Communication between and among consortium team members is essential to the success of the consortium. Applications must include a strategy for sharing data in real time and using information technologies to facilitate timely and effective communication and cooperation. The communication plan should specify the processes and tools to be used for regular and structured communication. The consortium should take full advantage of state-of-the-art communication and data sharing tools in addition to formal and informal meetings. The framework for the communication plan must be part of the application and the individual(s) who will maintain the data sharing and communications technologies must be identified.Provide an effective, coordinated administrative management plan that integrates and optimizes the research and collaborations. The Consortium Director is required to commit a minimum level of time and effort of 25% to direct and manage an initiative of this magnitude, as well as lead their own project team. The Consortium Director must have the scientific ability and proven administrative ability to oversee large research programs and a proven record of leadership, including experience in the effective use of communication tools and the management of multifaceted and multidisciplinary projects. The administrative management plan must explain how the consortium will be organized and managed, and specify the processes and tools to be used for project meeting scheduling, reviews of research findings, ensuring multidisciplinary authorship of all publications arising from the consortiums work, and other issues of common concern to the consortium and its investigators. The administrative management plan also must describe procedures and processes that will be used to maximize the resources (e.g., databases, animal models) and products (e.g., antibodies) generated by the consortium and how these resources and products will be made available to the scientific community. A portion of the total direct budget costs must be reserved for a program manager.Award Structure: The Transformative Breast Cancer Consortium Award is structured to accommodate up to five PIs (the Consortium Director and three or four Project Team PIs). The Consortium Director will be responsible for the majority of the administrative tasks associated with application submission and the day-to-day management of the consortium. In addition, the Consortium Director will be responsible for leading their own project team. The Consortium Director and Project Team PIs each have different submission requirements; however, all PIs should contribute significantly to the development of the proposed research project, including the Project Narrative, Statement of Work (SOW), and other required components. If recommended for funding, each PI will be named on separate awards to the recipient organizations. For individual submission requirements for the Consortium Director and Project Team PIs, refer to Section II.D.2, Content and Form of the Application Submission.The Consortium Director, Project Team PIs, and consumer advocates will be required to present an update on progress toward accomplishing research milestones and goals of the consortium and each project at an annual In-Progress Review (IPR) Meeting for the Transformative Breast Cancer Consortium Award. The intent of the IPR Meeting is to assess research progress, address problems, and define future directions. Annual IPR Meetings will be held at the conclusion of year 1 and every subsequent year in the period of performance and will be attended by members of the BCRP Programmatic Panel, CDMRP staff, and the USAMRAA Grants Officer to facilitate oversight and provide feedback to the consortium. IPR Meetings will either be held in person in the National Capital Region or virtually, at the discretion of the government. Continued funding may be contingent upon the successful completion of specific research milestones and goals. Research milestones from the approved SOW will be determined during the award negotiation process.In addition to IPR Meetings, each consortium must hold biannual workshops, which may be held at the PIs institutions or virtually, to facilitate ongoing communication and exchange of information within the consortium, as well as with advisory board(s) and/or steering committee(s).

This funding opportunity supports U.S. institutions in establishing a national center to coordinate and enhance research on Alzheimer's Disease and related dementias through data collection, integration, and collaboration efforts.

This funding opportunity supports a variety of organizations in Pennsylvania to develop environmental education projects that promote stewardship and awareness of natural resources, particularly focusing on climate change, water quality, and environmental justice.

The Access to Recreation Program, an initiative of the Community Foundation for the Land of Lincoln, is designed to support accessible recreation projects for individuals with disabilities and special needs. This includes adaptive sports, games, and programs, as well as capital projects, addressing various needs such as sensory, physical, mobility, cognitive, developmental, emotional, and psychological disabilities. The foundation's mission, as evidenced by this program, aligns with fostering inclusive community participation and removing barriers to recreation. The program primarily targets nonprofit organizations, faith-based organizations, public or private schools, and units of government or municipalities that serve residents of Sangamon County, IL. The goal is to provide opportunities for people with disabilities to participate in indoor or outdoor recreation activities without barriers. The program seeks to fund initiatives that are specifically designed for and/or about people with disabilities but are also available to the general public, promoting broader community inclusion. The program prioritizes requests that support accessible recreation, focusing on activities that enable participation for individuals with disabilities. This includes projects that facilitate adaptive sports, games, and various recreational programs. The emphasis is on creating an environment where disabilities do not hinder access to recreational activities, thereby enhancing the quality of life for individuals with special needs within Sangamon County. Expected outcomes include increased participation of people with disabilities in recreational activities, the development of more inclusive recreational programs, and the establishment of accessible facilities. Measurable results could include the number of individuals served, the types of adaptive programs implemented, and the improvements made to existing facilities to enhance accessibility. The foundation's strategic priorities appear to revolve around community well-being and equitable access, with a theory of change that posits by funding accessible recreation, they can directly improve the health, social integration, and overall life satisfaction of people with disabilities in their service area.

This grant provides funding for innovative research and development of advanced quantum computing systems that integrate various architectural approaches to significantly improve performance, targeting a wide range of organizations including universities, businesses, and research centers.

This program honors and recognizes women leaders in the Denver metro area who demonstrate exceptional leadership, innovation, and community impact through their professional and volunteer efforts.

This funding opportunity provides up to $10,000 to nonprofit organizations and educational institutions in Oklahoma for projects that preserve and digitize important humanities collections to enhance public access and research.

This funding opportunity supports the establishment of a center to coordinate research on cellular senescence, aiming to improve health outcomes by identifying tissue-specific markers and developing new therapeutic strategies, targeting a wide range of eligible applicants including educational institutions, nonprofits, and businesses.

This grant provides financial support to non-profit organizations focused on social betterment, including disaster relief, basic needs, education in STEM fields, health initiatives, and programs for individuals with disabilities.

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This funding opportunity supports early-career researchers and community-based organizations in developing innovative health technologies and interventions to improve health outcomes.

The Long Island Sound Futures Fund (LISFF), managed by the National Fish and Wildlife Foundation (NFWF) in collaboration with the U.S. Environmental Protection Agency (EPA) and the Long Island Sound Study (LISS), seeks to restore the health and living resources of Long Island Sound. This grant program, with approximately $12 million available in 2024, aligns with the foundation's mission by supporting efforts to test innovative conservation approaches, deliver transformative projects, and engage communities that value and protect the Sound. Major funding is provided by EPA through the LISS, with additional support from the U.S. Fish and Wildlife Service, Natural Resources Conservation Service, and Zoetis Foundation, demonstrating a collaborative strategic approach to environmental conservation. The LISFF targets a broad range of beneficiaries, including non-profit 501(c) organizations, state government agencies, local and municipal governments, Tribal Governments and Organizations, and educational institutions. The impact goals are centered on improving water quality, enhancing and restoring coastal habitats, and fostering sustainable and resilient communities around the Long Island Sound. The program’s strategic priorities are guided by the Long Island Sound Comprehensive Conservation and Management Plan 2020-2024 Update (CCMP), which emphasizes three core themes: Clean Waters and Healthy Watersheds, Thriving Habitats and Abundant Wildlife, and Sustainable and Resilient Communities. Cross-cutting principles of resiliency to climate change, long-term sustainability, and environmental justice are also integral to the program's theory of change. Under the "Clean Waters and Healthy Watersheds" theme, the program prioritizes reducing nitrogen pollution, combined sewer overflows, impervious cover, stormwater runoff, and point and nonpoint source loading. This includes funding for "shovel-ready" projects that result in quantifiable pollutant prevention, particularly those addressing water quality at a larger scale. Planning activities, such as community engagement, feasibility studies, site assessments, conceptual design, and final design and permitting, are also supported. Projects in the Upper Basin states (MA, NH, VT) are specifically focused on quantifiable nitrogen/nutrient prevention with a documented benefit to Long Island Sound. The "Thriving Habitats and Abundant Wildlife" theme focuses on enhancing or restoring coastal habitats to maintain resilience and function, supporting fish, bird, and wildlife populations, and sustaining the Sound's ecological balance. This involves implementing "shovel-ready" habitat restoration and nature-based or green-gray hybrid resilience projects, as well as planning activities for such projects. The program also aims to foster diverse, balanced, and abundant populations of fish, birds, and wildlife, encouraging proposals that consider the LISS Habitat Restoration Guidelines. The "Sustainable and Resilient Communities" theme supports vibrant, informed, and engaged communities through projects that offer hands-on conservation experiences. Expected outcomes include quantifiable pollutant reductions, enhanced and restored coastal habitats, increased resilience to climate change, and more engaged communities actively participating in the Sound's protection and sustainability. For water quality projects, measurable results will include quantifiable pollutant prevention, particularly nitrogen/nutrient reductions. For habitat projects, long-term maintenance plans and ecological improvements are expected. The LISFF's strategic framework, rooted in the CCMP, aims to accelerate local and regional water quality improvements, natural resource restoration, coastal resilience, environmental justice, and community outreach, ultimately leading to a healthier, more productive, and resilient Long Island Sound for both people and wildlife.

This funding opportunity provides financial support to early-career researchers at less research-intensive institutions, helping them establish their independent research careers in computer and information science.

This grant provides funding for multidisciplinary research and educational initiatives aimed at improving our understanding of wildland fire dynamics and enhancing community resilience to wildfires, targeting a wide range of stakeholders including academics, local communities, and Indigenous groups.

The District of Columbia Department of Health (DC Health) is offering a grant program aimed at improving the recruitment and retention of the dental workforce within the District. This initiative directly aligns with the broader mission of enhancing public health by addressing critical shortages in dental care, particularly in designated Health Professional Shortage Areas (HPSAs). By strengthening the dental workforce, DC Health seeks to ensure greater access to oral health services for all residents, thereby contributing to the overall well-being of the community. The primary target beneficiaries of this grant are dental professionals practicing or intending to practice in dental HPSAs. The impact goals are to alleviate the shortage of dental workers, reduce burnout among existing staff, and create more stable and effective dental care environments. The grant prioritizes the implementation or development of targeted training programs, the creation of initiatives to address organizational gaps impacting oral health workforce retention, and other strategies designed to combat burnout within the dental field. Expected outcomes include an increase in the number of dental professionals working in HPSAs, a reduction in staff turnover rates, and the establishment of sustainable and scalable approaches to meet the needs of dental organizations. Measurable results will likely involve tracking recruitment numbers, retention rates, and the successful implementation of new programs aimed at improving workforce stability. The goal is to identify and address the drivers of administrative and clinical support staff retention, ensuring a robust and resilient oral health workforce. The funding available for this project is substantial, with an anticipated amount of $80,000, and individual awards ranging from $60,000 to $80,000. The project period is set to begin on August 1, 2024, and conclude on July 31, 2025. Eligibility is extended to Federally Qualified Health Centers and dental clinics currently providing care in dental Health Professional Shortage Areas. This strategic investment reflects DC Health's commitment to a theory of change that posits by directly supporting the dental workforce, the District can achieve significant improvements in oral health equity and access.

The Department of Cultural Affairs (DCA) is offering the 2023-2024 Public-Space Activation Fund (PAF), a grant program aimed at supporting activities that revitalize public spaces within the City of Los Angeles, California. This initiative aligns with the DCA's mission to enrich the cultural life of the city by fostering community engagement and providing accessible cultural experiences. The grant seeks to fund projects that transform public areas into vibrant hubs of activity, reflecting a commitment to broad public benefit and cultural accessibility. The primary beneficiaries of the PAF are the residents and visitors of Los Angeles, particularly those who participate in or attend the various public events and activities supported by the fund. The impact goals include enhancing community cohesion, celebrating cultural diversity, and providing opportunities for cross-cultural learning. By supporting a range of accessible events, the fund aims to improve the quality of public life and create inclusive environments for artistic and cultural expression. The PAF prioritizes projects falling under four main categories, with specific emphasis on International Festivals & Intercultural Foods (IFIF). IFIF grants, typically ranging from $7,500 to $10,000, are designed for pop-up or festival-style events such as community picnics, outdoor festivals, block parties, and food/food-truck festivals. Additionally, creative enhancements to farmers' markets that incorporate live performing arts and cultural activities are highly encouraged. These projects are expected to embrace multicultural themes and feature entertainment suitable for family-friendly, street-adjacent spaces like public parks, schoolyards, and parking lots. Expected outcomes include a measurable increase in public attendance at cultural events, greater community participation in organized activities, and a visible enhancement of public spaces. The success of IFIF projects, for instance, will be measured by their ability to promote opportunities for cross-cultural learning and engage diverse audiences through multicultural entertainment. The DCA's strategic priority is to activate public spaces, and this grant program serves as a direct implementation of that theory of change, believing that by funding accessible cultural events, they can foster a more connected and culturally rich urban environment.

This program provides funding to interdisciplinary teams working on innovative projects that enhance public access to research data and promote open science through collaborative cyberinfrastructure initiatives.

The Community Foundation for Monterey County offers grants ranging from $1,000 to $10,000 to support initiatives that increase awareness, promote acceptance, and improve the quality of life for the LGBTQ+ community in Monterey County, CA, with a focus on arts and culture, education, civil rights, health, mental health, organizational capacity building, and programs for youth and seniors.

The DoD Traumatic Brain Injury and Psychological Health, Clinical Trial Award is a funding opportunity aimed at supporting the implementation of clinical trials that can significantly impact psychological health conditions and/or traumatic brain injury through the development of healthcare products, technologies, or practice guidelines.

This funding opportunity provides financial support for nonprofit organizations, educational institutions, and community groups to implement projects that enhance maritime cooperation, economic ties, and regional security in the Cook Islands and Niue.