Grants for Nonprofits - Science and Technology

The purpose of the RRTCs, which are funded through the Disability and Rehabilitation Research Projects and Centers Program, is to achieve the goals of, and improve the effectiveness of, services authorized under the Rehabilitation Act through well-designed research, training, technical assistance, and dissemination activities in important topical areas as specified by NIDILRR. These activities are designed to benefit people with disabilities, family members, rehabilitation service providers, policymakers and other research stakeholders. The purpose of this particular RRTC is to conduct research, training, technical assistance, and related activities to contribute to improved employment outcomes of adults with Serious Mental Illness. NIDILRR plans to make one grant under this opportunity. The grant will have a 60-month project period, with five 12-month budget periods.

The FY24 VRP MCRA is intended to support patient-oriented vision injury research and develop research expertise of highly motivated military or civilian clinicians in training. Research supported by the MCRA can be a standalone study of high impact to vision injury care or the generation of clinical research data in preparation for a more expansive study.Each MCRA must be led by an established clinician or Ph.D. clinical scientist who will serve as Principal Investigator (PI) of the award. Key personnel must include a clinician in training (e.g., a fellow, resident, junior clinician, clinician in a Ph.D. program). The clinician in training should have sufficient time remaining in their training program to complete the research proposed under the MCRA. The clinician in training will conduct the proposed research under the mentorship of the PI, with support from supporting personnel as appropriate. While additional junior scientists or clinicians may participate in the research, only one clinician in training may be designated as mentee. A Letter of Organizational Support and Mentee Eligibility, signed by the Department Chair or appropriate organization official, and a Letter of Commitment, signed by the mentee, should be submitted as part of Attachment 2: Supporting Documentation.For the purposes of this award mechanism, clinical research is defined as research conducted with human subjects or research on material of human origin, such as tissues or specimens or data obtained from human subjects. Documentation of Institutional Review Board (IRB)/ Ethics Committee (EC) approval or exemption by December 1, 2024, is required for an MCRA application to be considered for funding. See Attachment 2: Supporting Documentation for additional detail.The MCRA may not be used to conduct preclinical research (including animal research) or clinical trials.A clinical trial is defined in the Code of Federal Regulations, Title 45, Part 46.102 (45 CFR 46.102) as a research study in which one or more human subjects are prospectively assigned to one or more interventions (which may include a placebo or another control) to evaluate the effects of the interventions on biomedical or behavioral health-related outcomes.Studies that do not seek to measure safety, effectiveness, and/or efficacy outcome(s) of an intervention are not considered clinical trials.Studies that retrospectively analyze data generated from previously conducted clinical trial(s) are not considered a clinical trial.

The Social Justice Fund NorthWest (SJF) is offering the 2024 Base Building Grant, aimed at strengthening grassroots organizations in Idaho, Montana, Oregon, Washington, and Wyoming. This grant directly aligns with SJF's mission to foster social justice by investing in community organizing as a primary strategy. The program focuses on "Base Building," defined as a tactic that expands the number and engagement of people who share a vision for social justice and actively work to achieve it through organized strategies. This approach underscores SJF's strategic priority of empowering communities to drive systemic change. The grant targets organizations committed to community organizing and led by those most directly affected by the issues they address. Specifically, SJF prioritizes organizations with at least 51% leadership from Black, Indigenous, and people of color communities, or those working predominantly in reservation, rural, or small-town communities. The impact goals are to build collective power, widen the base of engaged individuals, develop strong leadership within communities, and implement effective long-term strategies. The expected outcomes include a critical mass of collective power capable of winning and defending policy, cultural, or institutional changes, as well as a diverse and actively engaged membership. SJF's community organizing framework emphasizes four key areas: Collective Power, Widening the Base, Leadership Development, and Strategy and Long-Term Planning. Under Collective Power, the focus is on building a diverse membership and achieving policy or cultural wins. Widening the Base involves fostering authentic relationships with those most affected, recruiting new people, and using varied, tailored communication methods, including face-to-face engagement. Leadership Development ensures clear entry points to leadership, accessible political education, and continuous engagement and agitation. Finally, Strategy and Long-Term Planning requires organizations to develop and adapt a comprehensive base-building plan with clear goals, timelines, infrastructure, and accountability structures. The grant, providing $100,000 over two years ($50,000 annually), is open to nonprofit organizations, tribal agencies, or fiscally sponsored groups with 501(c)3 or 501(c)4 status, or federally recognized American Indian tribal governments. This funding mechanism directly supports SJF's theory of change, which posits that sustained investment in community-led organizing, focused on these core elements, will lead to meaningful and lasting social justice outcomes in the specified regions.

The United States Agency for International Development (USAID) is issuing this Broad Agency Announcement (BAA) to seek participants to co-create, co-design, co-invest, and collaborate on creating, piloting, and scaling innovative research and development interventions utilizing innovative health practices to help reduce disease and mortality rates worldwide. USAID invites organizations and companies to submit an Expression of Interest (EOI) and participate in generating novel tools and approaches that accelerate and sustain improved health outcomes in low-and-middle-income countries (LMICs). The intent of the BAA is to allow co-creation and co-design to the maximum extent to create high quality, effective partnerships with great efficiency in time and resources. USAID is seeking new applications of research development, science, partnerships, and innovative practices in global health that provide the best value to the Government. USAID will invite selected for-profit and non-profit, public and private organizations, as detailed below, to co-create innovative research and development (R) solutions to the Problem and Challenge Statements stated in this BAA, including those organizations that have ideas, expertise, resources, and/or funding to add to potential solutions. In particular, this BAA welcomes co-creation from local partners based in LMICs, including the private sector, faith-based organizations, and other non-traditional USAID partners, to increase the presence and voices of local populations in solving their own health challenges.The intent of the BAA is to enable and encourage co-creation and co-design in order to generate high quality ideas and effective partnerships with improved efficiency in time and resources. Other types of collaboration can also include co-investing:Co-Investing: USAID wants to align goals with the partners under this BAA, to facilitate shared responsibility, shared risk, and shared resourcing. Shared resourcing requires that cash and other resources, both tangible and intangible, such as in-kind contributions, expertise, intellectual property, brand value, high-value coordination, and access to key people, places, and information, are directed towards reaching the solution to the Problem/Challenge. Co-investing does not require equal shared resources (such as 1:1 leverage), but rather resource contributions that are appropriate to the specific projects objectives, considering the comparative advantages brought by the participation of each party.

The 2024 Farm-to-School Competitive Grants Program, offered by the New York State Department of Agriculture and Markets, aims to increase the promotion and use of New York State produced foods in K-12 school cafeterias. This initiative seeks to build relationships between New York farmers, food hubs, producers, processors, and distributors with schools, ultimately benefiting school-age children by enhancing the quality of food served and fostering local agricultural connections. The program aligns with a broader mission of improving nutrition, exposing students to new, local culinary experiences, and increasing agricultural education opportunities. Target beneficiaries for this program include K-12 School Food Authorities, charter schools, not-for-profit organizations, and Indian tribal organizations within New York State. The impact goals are centered on increasing the volume and variety of New York State farm products purchased by schools and served in school meal programs. Secondary goals include fostering agricultural education and improving student nutrition through exposure to local foods. The program prioritizes projects that increase the purchase of New York specialty crops, build relationships between schools and New York farm product suppliers, and encourage agricultural and nutrition education, gardening activities, and relationship building with local agricultural food businesses and farmers. Projects that partner with producers or food processors are strongly encouraged, highlighting a focus on strengthening the entire farm-to-school supply chain. Challenges addressed by the program include seasonality, inconsistent quality/quantity, processing/packaging needs, complex bidding processes, distribution logistics, lack of equipment/skills for fresh produce, connecting diverse populations with culturally appropriate foods, and insufficient training for culinary staff. Expected outcomes and measurable results revolve around the increased procurement and serving of New York State farm products in school meal programs. The program, which has been in place since 2015, anticipates that successful projects will demonstrate a greater integration of local foods into school meals. While specific metrics are not detailed, the objective to "increase the volume and variety" implies a quantitative measure of growth in local food purchasing. The total funding available is $1,500,000, with individual grant awards ranging from $50,000 to $100,000, and $300,000 set aside for first-time recipients, indicating a strategic effort to expand participation and impact over the two-year project duration (September 1, 2024, to August 31, 2026).

The Business Oregon grant funding aims to address longstanding economic inequities by providing culturally responsive services, outreach, support, and resources to eligible beneficiaries. Unlike traditional poverty alleviation programs, the EEIP is a wealth-building program that prioritizes outcomes related to self-sufficiency, economic stability, and economic equity. The program is funded by an $8 million one-time investment from the Oregon State Legislature. Successful applicants will demonstrate a meaningful track record of delivering programs or resources within key eligible areas: land ownership and other real property acquisition (including principal residences), entrepreneurship and business development, workforce development, or intergenerational wealth-building. Organizations receiving funds will directly provide outreach, support, and programming to eligible beneficiaries in one or more of these areas. Eligible beneficiaries are defined as “disadvantaged individuals, families, businesses, and communities” whose future is at risk due to two or more risk factors, as detailed in ORS 285B.761. Awards must be aimed at narrowing wealth gaps. Preference will be given to intermediary organizations with a proven track record of successfully delivering programs and resources that align with the goals and aspirations of the EEIP and possess the capacity to complete programs and expend all funds by June 30, 2025. Expected outcomes include increased self-sufficiency, economic stability, and economic equity for disadvantaged individuals, families, businesses, and communities in Oregon. The program's strategic priorities are centered on wealth-building, a departure from traditional poverty alleviation, to foster long-term economic well-being and reduce wealth disparities across the state. This initiative reflects a theory of change that by investing in key economic development areas and supporting capable intermediary organizations, sustainable economic growth and equity can be achieved for at-risk populations.

This funding opportunity provides financial support for innovative research in advanced scientific computing and extreme-scale science, targeting a wide range of applicants including universities, for-profit companies, and federal laboratories, to tackle challenges in high-performance computing, quantum technologies, and artificial intelligence.

This grant provides funding for experienced researchers at U.S. higher education institutions to explore new engineering fields or reestablish their research after a break, with a focus on innovation, societal impact, and promoting diversity and inclusion.

The Office of Economic and Workforce Development (OEWD) is offering grants to support San Francisco’s residents, businesses, visitors, and workers by providing critical economic and workforce development resources. This Request for Proposals (RFP) encompasses four distinct program areas, with an anticipated total funding of $2.38 million for initial grant awards. The grants are designed to support programs delivered through three key OEWD divisions: Business Development, Community Economic Development (formerly Invest In Neighborhoods), and Workforce Development. The target beneficiaries of these programs include various communities within San Francisco. For Community Economic Development, the focus is on Castro cultural activation, specifically uplifting Queer and Transgender Asian American and Pacific Islander communities. Workforce Development programs target workers through the Industries of Opportunity-Worker Cooperative Program and youth and young adults through the Industries of Opportunity-Youth and Young Adult Food Sovereignty program. Business Development programs aim to benefit the broader community through Union Square Park Programming. The grant prioritizes specific areas with defined funding allocations. Community Economic Development programs, focusing on Castro cultural activation, have a funding of $30,000. Workforce Development programs include $950,000 for the Worker Cooperative Program ($425,000 per program year) and $400,000 for the Youth and Young Adult Food Sovereignty program ($200,000 per program year). Business Development programs, specifically for Union Square Park Programming, are allocated $1,000,000. Successful proposals are expected to be funded for up to six years, concluding no later than June 2030, which indicates a long-term commitment to the initiatives. The eligibility criteria require applicants to be a nonprofit 501(c)(3), 501(c)(4), or 501(c)(6) organization, registered with the IRS and in good standing with relevant California state entities, and eligible to do business with the City and County of San Francisco. Expected outcomes include economic growth, workforce development, and community empowerment within the targeted areas of San Francisco, aligning with OEWD’s mission to support the city's residents and economy.

This funding opportunity supports Anne Arundel County Public School clubs and youth organizations in implementing peer-led education programs focused on preventing substance misuse among youth.

The overall goal of ProCON Global is to promote open, interoperable, reliable, and secure commercial undersea cable systems around the world. The project will provide technical assistance to key decision-makers, including policymakers, regulators, and technology companies in emerging economies, to promote evaluation processes and investment in secure and trusted vendors when establishing undersea cable network supply chains. Technology companies include telecommunications operators/carriers, major technology and security firms, innovators, and content and cloud providers.

The intent of the Breakthrough Award is to support promising research that has high potential to lead to or make breakthroughs in breast cancer. The critical components of this award mechanism are:Impact: Research supported by the Breakthrough Award will have the potential for a major impact and accelerate progress toward ending breast cancer. The impact may be near-term or long-term, but must move beyond a minor advancement and have the potential to lead to a fundamentally new approach that is significantly more effective than interventions already approved or in clinical development. Applications are expected to identify the breast cancer patients or at-risk individuals who would ultimately benefit from the proposed research.Research Scope: The Breakthrough Award is structured with four different funding levels. The levels are designed to support major (but not all) stages of research that will lead to clinical application. Each level has a defined research scope. It is the responsibility of the Principal Investigator (PI) to select the level that aligns with the scope of the proposed research. The funding level should be selected based on the research scope defined in the program announcement, and not on the amount of the budget.The current program announcement discusses the Breakthrough Award Level 3. Funding Levels 1, 2, and 4 are available under other program announcements (HT942524BCRPBTA12 for Levels 1 and 2 and HT942524BCRPBTA4 for Level 4). The PI is strongly encouraged to review the research scope defined under each funding level as described in the corresponding Breakthrough Award program announcements before submitting the pre-application. An application that does not meet the intent of the funding level selected will not be recommended for funding, even if it might meet the intent of a different funding level.The following is a general description, although not all-inclusive, of the scope of research projects that would be appropriate to propose under the current program announcement:Funding Level 3: Advanced translational studies with a high degree of project readiness. Where relevant, proof of availability of and access to necessary data, human samples, cohort(s), and/or critical reagents must be provided. If the proposed research would ultimately require U.S. Food and Drug Administration (FDA) involvement, applications must demonstrate availability of, and access to, clinical reagents (e.g., therapeutic molecules) and patient population(s). Applications must state a realistic timeline for near-term clinical investigation. Small-scale clinical trials (e.g., first in human, phase 1/1b) may be appropriate.Partnering PI Option: The Breakthrough Award encourages applications that include meaningful and productive partnerships between investigators. The Partnering PI Option is structured to accommodate two PIs. One PI will be identified as the Initiating PI and will be responsible for the majority of the administrative tasks associated with application submission. The other PI will be identified as a Partnering PI. Both PIs should contribute significantly to the development of the proposed research project, including the Project Narrative, Statement of Work (SOW), and other required components. The PIs may have expertise in similar or disparate scientific disciplines, but each PI is expected to bring distinct contributions to the application. The application should clearly demonstrate that both PIs have equal intellectual input into the design of the project and will devote similar and appropriate levels of effort to the conduct of the project. It is expected that funding will be balanced between both PIs unless appropriately justified. New partnerships are encouraged, but not required. The application is expected to describe how the PIs unique expertise combined as a partnership will better address the research question, how the unique expertise that each individual brings to the application is critical for the research strategy and completion of the SOW, and why the work should be done together rather than through separate efforts. To meet the intent of the Partnering PI Option, applicants are discouraged from being named as a Partnering PI on multiple Breakthrough Award Level 3 applications unless they are clearly addressing distinct research questions. Applications where one PI is providing samples, animal models, or investigational agents while the other PI is conducting most or all of the experiments and analyses do not meet the intent of the Partnering PI Option. If recommended for funding, each PI will be named on separate awards to the recipient organization(s). Each award will be subject to separate reporting, regulatory, and administrative requirements. For individual submission requirements for the Initiating and Partnering PIs, refer to Section II.D.2, Content and Form of the Application Submission.Personnel: Applications are expected to include an appropriate and robust research team with the combined backgrounds and breast cancer-related expertise to enable successful conduct of the project.Consumer Advocates: Applications are required to include consumer advocate involvement. The research team must include two or more breast cancer consumer advocates, who will be integral throughout the planning and implementation of the research project. Consumer advocates should be involved in the development of the research question, project design, oversight, recruitment, and evaluation, as well as other significant aspects of the proposed project. Interactions with other team members should be well integrated and ongoing, not limited to attending seminars and semi-annual meetings. As lay representatives, the consumer advocates must be individuals who have been diagnosed with breast cancer, and they should be active in a breast cancer advocacy organization. Their role in the project should be independent of their employment, and they cannot be employees of any of the organizations participating in the application. Their role should be focused on providing objective input on the research and its potential impact for individuals with, or at risk for, breast cancer. The consumer advocates should have a high level of knowledge of current breast cancer issues and the appropriate background and/or training in breast cancer research to contribute to the project.A congressionally mandated Metastatic Cancer Task Force was formed with the purpose of identifying ways to help accelerate clinical and translational research aimed at extending the lives of advanced state and recurrent patients. As a member of the Metastatic Cancer Task Force, CDMRP encourages applicants to review the recommendations (https://health.mil/Reference-Center/Congressional-Testimonies/2018/05/03/Metastatic-Cancer-Research) and submit research ideas to address these recommendations provided they are within the limitations of this funding opportunity and fit within the FY24 BCRP priorities.Innovative research involving nuclear medicine and related techniques to support early diagnosis, more effective treatment, and improved health outcomes of active-duty Service Members and their Families is encouraged. Such research could improve diagnostic and targeted treatment capabilities through noninvasive techniques and may drive the development of precision imaging and advanced targeted therapies.The proposed research must be relevant to active-duty Service Members, Veterans, military beneficiaries, and/or the American public. Collaborations between researchers at military or Veteran institutions and non-military institutions are strongly encouraged. These relationships can leverage knowledge, infrastructure, and access to unique clinical populations that the partners bring to the research effort, ultimately advancing cancer research that is of significance to the Warfighter, military Families, and the American public.Title 45, Part 46.102 (45 CFR 46.102) as a research study in which one or more human subjects are prospectively assigned to one or more interventions (which may include a placebo or another control) to evaluate the effects of the interventions on biomedical or behavioral health-related outcomes.Studies that do not seek to measure safety, effectiveness, and/or efficacy outcome(s) of an intervention are not considered clinical trials.For the purposes of this funding opportunity, research that meets the definition of a clinical trial is distinct from clinical research. Clinical research encompasses research with human data, human specimens, and/or interaction with human subjects. Clinical research is observational in nature and includes:(1) Research conducted with human subjects and/or material of human origin such as data, specimens, and cognitive phenomena for which an investigator (or co-investigator) does not seek to assess the safety, effectiveness, and/or efficacy outcomes of an intervention. Research meeting this definition may include but is not limited to: (a) mechanisms of human disease, (b) diagnostic or detection studies (e.g., biomarker or imaging), (c) health disparity studies, and (d) development of new technologies.(2) Epidemiologic and behavioral studies that do not seek to assess the safety, effectiveness, and/or efficacy outcomes of an intervention.(3) Outcomes research and health services research that do not fit under the definition of clinical trial.Excluded from the definition of clinical research are in vitro studies that utilize human data or specimens that cannot be linked to a living individual and meet the requirements for exemption under 46.104(d)(4) of the Common Rule.The funding instrument for awards made under the program announcement will be grants (31 USC 6304).The anticipated direct costs budgeted for the entire period of performance for an FY24 BCRP Breakthrough Award Level 3 should not exceed $4M for applications with a single PI or $5M if applying under the Partnering PI Option. Refer to Section II.D.5, Funding Restrictions, for detailed funding information.Awards supported with FY24 funds will be made no later than September 30, 2025.The CDMRP expects to allot approximately $13.95M to fund approximately two BCRP Breakthrough Award Level 3 applications. Funding of applications received is contingent upon the availability of federal funds for this program, the number of applications received, the quality and merit of the applications as evaluated by peer and programmatic review, and the requirements of the government. Funds to be obligated on any award resulting from this funding opportunity will be available for use for a limited time period based on the fiscal year of the funds. It is anticipated that awards made from this FY24 funding opportunity will be funded with FY24 funds, which will expire for use on September 30, 2030.

The Washington State Department of Commerce (COMMERCE) is seeking proposals for a project focused on weatherizing multifamily buildings across Washington State. This initiative aims to increase energy efficiency and reduce the energy burden for residents in these buildings. The program aligns with a broader mission of improving community well-being and sustainability by enhancing housing quality and affordability through energy conservation. The grant is designed to expand existing weatherization services or establish new agencies dedicated to this specific purpose, addressing a critical need within the state. The primary beneficiaries of this grant program are residents of multifamily buildings throughout Washington State, particularly those in traditionally hard-to-reach markets and underserved regions. The impact goal is to significantly lower energy costs for these residents while simultaneously improving the energy efficiency of their homes. This will lead to more comfortable living conditions and financial relief for households, contributing to overall community resilience. The program also aims to address health and safety remediation in these properties, further enhancing the living environment for beneficiaries. COMMERCE is prioritizing services that focus solely on increasing energy efficiency and lowering the energy burden in multifamily buildings. A key focus is on reaching underserved areas and a broader category of homes that may have been overlooked by previous initiatives. This strategic focus ensures that the grant funding will have the most significant impact where it is needed most, aligning with a theory of change that posits that targeted interventions in housing energy efficiency can lead to measurable improvements in resident welfare and environmental sustainability. The expected outcomes include a measurable increase in the number of weatherized multifamily buildings across the state, resulting in quantifiable reductions in energy consumption and associated costs for residents. The grant specifies a funding period from July 10th, 2024, to June 30th, 2027, with a total budget not to exceed $7,301,514.13. This funding is allocated across West, East, Central, and Coastal North regions of Washington, with specific amounts designated for program operations and administrative awards. Successful contractors will demonstrate experience in weatherizing multifamily buildings and implementing residential energy efficiency measures, ensuring the effective delivery of the program's intended results.

This funding opportunity provides resources to enhance the genome sequencing capabilities of laboratories in Latin America to investigate potential biological weapons attacks.

This grant provides funding to nonprofit organizations in New Mexico that focus on improving the lives of youth and families through programs in areas such as at-risk youth support, community enrichment, education, STEM, and arts and culture.

This funding opportunity supports various organizations in Maine to develop and implement projects that expand affordable housing options and workforce housing through community planning and collaboration.

This funding opportunity supports research projects that use genome editing techniques to explore the genetic factors contributing to substance use disorders, encouraging diverse organizations to participate in advancing addiction science.

The Sisters of St. Francis (Sylvania) Foundation Grant Program, in partnership with the Greater Toledo Community Foundation, is offering grants ranging from $5,000 to $50,000 to 501(c)(3) organizations in selected counties of Ohio and Michigan, to support programs that combat human trafficking, assist immigrants and refugees, advance social justice and equal opportunity, and promote environmental preservation and sustainability.

This grant provides funding for researchers and organizations to develop innovative technologies and processes that improve water treatment methods, reduce costs and environmental impacts, and enhance the efficiency of desalination and water purification systems.

CNY Arts is accepting applications for the Tier Three Project Support Program, offering grants between $1,000 to $10,000 for arts and cultural projects executed by Onondaga County nonprofit organizations in New York, with the application deadline on October 21, 2024.