Grants for Public and State controlled institutions of higher education - Science and Technology

This grant provides funding for experienced researchers at U.S. higher education institutions to explore new engineering fields or reestablish their research after a break, with a focus on innovation, societal impact, and promoting diversity and inclusion.

The Pfizer Fellowship Grant for Transthyretin Cardiac Amyloidosis is a competitive grant initiative aimed at advancing the professional development of healthcare professionals specializing in the diagnosis and management of ATTR cardiac amyloidosis. This grant is dedicated to enhancing academic and clinical understanding of the disease through research and education. Offered to U.S.-based academic institutions, the program supports fellowship roles for Cardiologists or Heart Failure Advanced Practice Providers, emphasizing a balance of clinical practice, research, and educational outreach. The grant ensures that the supported activities are independent of Pfizer’s commercial interests, focusing on fostering substantial advancements in the field of cardiac health.

This funding opportunity supports innovative bioscience research projects in Delaware that have the potential for significant economic impact, targeting researchers and businesses in the developmental stage.

This funding opportunity provides resources to enhance the genome sequencing capabilities of laboratories in Latin America to investigate potential biological weapons attacks.

This funding opportunity supports research projects that use genome editing techniques to explore the genetic factors contributing to substance use disorders, encouraging diverse organizations to participate in advancing addiction science.

This grant provides funding for researchers and organizations to develop innovative technologies and processes that improve water treatment methods, reduce costs and environmental impacts, and enhance the efficiency of desalination and water purification systems.

The long-range goal of the Research Training Groups in the Mathematical Sciences (RTG) program is to strengthen the nation's scientific competitiveness by increasing the number of well-prepared U.S. citizens, nationals, and permanent residents who pursue careers in the mathematical sciences, be they in academia, government, or industry. The RTG program supports efforts to improve research training by involving undergraduate students, graduate students, postdoctoral associates, and faculty members in structured research groups pursuing coherent research programs. Research groups supported by RTG must include vertically-integrated activities that span the entire spectrum of educational levels from undergraduates through postdoctoral associates.

This funding opportunity is designed for research institutions affiliated with the Desert Southwest Cooperative Ecosystem Studies Unit to study vegetation health and water use in the Lower Colorado River's riparian areas using remote sensing technologies.

This grant provides $1 million to a qualified nonprofit or educational institution in California to develop a project aimed at improving health outcomes and reducing disparities for low-income and marginalized communities in San Diego and Imperial Counties.

This program provides matching funds to Nebraska businesses collaborating with local colleges or universities on research and development projects that create or improve products and processes to boost revenue.

This funding opportunity provides financial support for research and development projects that improve forensic science practices and technologies, targeting a wide range of eligible entities including government agencies, educational institutions, and nonprofit organizations.

This funding opportunity supports projects that utilize NASA Earth observations to improve decision-making in ecological conservation and management, targeting organizations involved in areas like habitat restoration, biodiversity protection, and invasive species management.

This funding opportunity supports a wide range of research and technology development in space and Earth sciences for various organizations, including government and private entities, both domestically and internationally.

This program provides funding and support to entrepreneurs nationwide, particularly from Massachusetts, to help them develop and commercialize innovative climate technology solutions.

This funding opportunity provides financial support to early-career academic scientists and engineers in the U.S. to advance research relevant to the Navy's science and technology priorities.

This grant provides funding for researchers to conduct innovative studies on ovarian cancer, focusing on impactful solutions that benefit patients and their families.

This program provides funding to support collaborations between formal methods researchers and experts in various computer and engineering fields to improve system design and reliability through innovative methodologies and educational initiatives.

The FY24 PCRP Exploration Hypothesis Development Award supports the exploration of highly innovative, untested, potentially high-gain concepts, theories, paradigms, and/or methods that address an important problem relevant to one or more of the FY24 PCRP Overarching Challenges. This award is designed to provide investigators the opportunity to pursue serendipitous observations that may reveal entirely new avenues for investigation. Results of studies conducted through this award may provide the scientific premise upon which a new hypothesis can be based or initial proof of principle of an innovative hypothesis, laying the groundwork for future avenues of scientific investigation. Presentation of preliminary data is inconsistent with the intent of this award mechanism and is therefore strongly discouraged. However, logical reasoning and a sound scientific rationale for the proposed work must be described. Reviewers will be blinded to the identity of the Principal Investigator (PI), collaborator(s), and their organization(s). Refer to Section II.D.2.b.i, Full Application Submission Type, for more information. New for FY24: Clinical research is allowed. For the purposes of this funding opportunity, research that meets the definition of a clinical trial is distinct from clinical research. Clinical research encompasses research with human data, human specimens, and/or interaction with human subjects. Clinical research is observational in nature and includes: (1) Research conducted with human subjects and/or material of human origin such as data, specimens, and cognitive phenomena for which an investigator (or co-investigator) does not seek to assess the safety, effectiveness, and/or efficacy outcomes of an intervention. Research meeting this definition may include but is not limited to: (a) mechanisms of human disease, (b) diagnostic or detection studies (e.g., biomarker or imaging), (c) health disparity studies, and (d) development of new technologies. (2) Epidemiologic and behavioral studies that do not seek to assess the safety, effectiveness, and/or efficacy outcomes of an intervention. (3) Outcomes research and health services research that do not fit under the definition of clinical trial. Excluded from the definition of clinical research are in vitro studies that utilize human data or specimens that cannot be linked to a living individual and meet the requirements for exemption under 46.104(d)(4) of the Common Rule. Clinical trials are not allowed. A clinical trial is defined in the Code of Federal Regulations, Title 45, Part 46.102 (45 CFR 46.102) as a research study in which one or more human subjects are prospectively assigned to one or more interventions (which may include a placebo or another control) to evaluate the effects of the interventions on biomedical or behavioral health-related outcomes. Studies that do not seek to measure safety, effectiveness, and/or efficacy outcome(s) of an intervention are not considered clinical trials. A congressionally mandated Metastatic Cancer Task Force was formed with the purpose of identifying ways to help accelerate clinical and translational research aimed at extending the lives of advanced state and recurrent patients. As a member of the Metastatic Cancer Task Force, the CDMRP encourages applicants to review the recommendations (https://health.mil/Reference-Center/Congressional-Testimonies/2018/05/03/Metastatic-Cancer Research) and submit research ideas to address these recommendations provided they are within the limitations of this funding opportunity and fit within the FY24 PCRP priorities. Innovative research involving nuclear medicine and related techniques to support early diagnosis, more-effective treatment, and improved health outcomes of active-duty Service Members and their Families is encouraged. Such research could improve diagnostic and targeted treatment capabilities through noninvasive techniques and may drive the development of precision imaging and advanced targeted therapies. Applications from investigators within the military services and applications involving multidisciplinary collaborations among academia, industry, the military services, the U.S. Department of Veterans Affairs (VA), and other federal government agencies are highly encouraged. These relationships can leverage knowledge, infrastructure, and access to unique clinical populations that the collaborators bring to the research effort, ultimately advancing research that is of significance to Service Members, Veterans, and/or their Families. If the proposed research relies on access to unique resources or databases, the application must describe the access at the time of submission and include a plan for maintaining access as needed throughout the proposed research. All projects should adhere to a core set of standards for rigorous study design and reporting to maximize the reproducibility and translational potential of clinical and preclinical research. The standards are described in SC Landis et al., 2012, A call for transparent reporting to optimize the predictive value of preclinical research, Nature 490:187-191 (https://www.nature.com/nature/ journal/v490/n7419/full/nature11556.html). While these standards are written for preclinical studies, the basic principles of randomization, blinding, sample-size estimation, and data handling derive from well-established best practices in clinical studies. The funding instrument for awards made under the program announcement will be grants (31 USC 6304). The anticipated direct costs budgeted for the entire period of performance for an FY24 Exploration Hypothesis Development Award should not exceed $150,000. Refer to Section II.D.5, Funding Restrictions, for detailed funding information. Awards supported with FY24 funds will be made no later than September 30, 2025. The CDMRP expects to allot approximately $3.60M to fund approximately 15 Exploration Hypothesis Development Award applications. Funding of applications received is contingent upon the availability of federal funds for this program, the number of applications received, the quality and merit of the applications as evaluated by peer and programmatic review, and the requirements of the government. Funds to be obligated on any award resulting from this funding opportunity will be available for use for a limited time period based on the fiscal year of the funds. It is anticipated that awards made from this FY24 funding opportunity will be funded with FY24 funds, which will expire for use on September 30, 2030. Research Involving Animals: All research funded by the FY24 PCRP Exploration-Hypothesis Development Award involving new and ongoing research with animals must be reviewed and approved by the USAMRDC Office of Human and Animal Research Oversight (OHARO; previously the Human Research Protection Office), Animal Care and Use Review Office (ACURO), in addition to the local Institutional Animal Care and Use Committee (IACUC) of record. IACUC approval at the time of submission is not required. Allow at least 3 to 4 months for ACURO regulatory review and approval processes for animal studies. Refer to the General Application Instructions for additional information.

To obtain a copy of the Funding Opportunity Announcement (FOA) please go to the ARPA-E website at https://arpa-e-foa.energy.gov. To apply to this FOA, Applicants must register with and submit application materials through ARPA-E eXCHANGE (https://arpa-e-foa.energy.gov/Registration.aspx). For detailed guidance on using ARPA-E eXCHANGE, please refer to the ARPA-E eXCHANGE User Guide (https://arpa-e-foa.energy.gov/Manuals.aspx). ARPA-E will not review or consider concept papers submitted through other means. For problems with ARPA-E eXCHANGE, email ExchangeHelp@hq.doe.gov (with FOA name and number in the subject line). Questions about this FOA? Check the Frequently Asked Questions available at http://arpa-e.energy.gov/faq. For questions that have not already been answered, email ARPA-E-CO@hq.doe.gov. The purpose of this modification is to incorporate changes to Funding Opportunity Announcement. Accordingly, this modification: Inserted new Exploratory Topic, Topic M: H2SENSE. See Table 1. Exploratory Topics, Appendix M, and Total Amounts to be awarded on Cover Page. Updated Language in Appendix L Section 5.

This funding opportunity provides financial support for public diplomacy projects that strengthen U.S.-Slovenian relations and enhance community safety, prosperity, and resilience through initiatives involving both American and Slovenian participants.