Grants for Small businesses - Science and Technology

This funding opportunity supports projects that develop and operate geologic field laboratories for carbon storage technology, targeting organizations with access to suitable sites for testing and advancing carbon capture solutions.

This funding opportunity provides financial support to U.S.-based small businesses for innovative research and development projects that address critical challenges in energy, environment, and national security.

This grant supports entrepreneurs and researchers in Pennsylvania by providing resources and funding to help turn innovative ideas into marketable products and services that benefit the community and beyond.

The FY24 OCRP Clinical Trial Translational Endpoints Research Award intends to support correlation of clinical trial-related data (e.g., biosample analysis, imaging, or epidemiological data) with clinical outcomes or responses to therapies. Correlative studies may be associated with a past, ongoing, or future clinical trial in order to associate various factors (genetic, DOD FY24 Ovarian Cancer Clinical Trial Translational Endpoints Research Award 4biochemical, environmental and others) with initiation, progression, metastasis, recurrence, prognosis, diagnosis or effect of intervention on ovarian cancer outcomes. The translational research should address high-impact or unmet needs in ovarian cancer. The proposed research may be hypothesis testing or may be designed to generate new hypotheses to be tested in follow-up clinical research. The award may not be used to directly support a clinical trial.

The Nebraska SBIR/STTR Initiative provides financial assistance to small businesses in Nebraska participating in the federal SBIR/STTR programs. This state initiative offers Phase 0 assistance to help businesses apply for federal Phase 1 funding and matching funds for successful Phase 1 and Phase 2 federal awards. The initiative aims to promote innovation and technology transfer among small businesses in Nebraska, with a total fund availability of up to $6 million per year. Grant renewed every year. Grant Annual opening/closing deadline: July 1st to June 30th

This program provides financial assistance to businesses in Wabasha for improving the exterior of their commercial or industrial buildings, promoting revitalization and private investment in the community.

The DoD Kidney Cancer, Clinical Trial Award is a funding opportunity aimed at supporting the implementation of clinical trials that have the potential to significantly impact the treatment or management of kidney cancer, with a focus on new products, pharmacologic agents, devices, clinical guidance, and emerging approaches and technologies.

The Heartland Regional Food Business Center is offering Business Builder Subawards ranging from $5,000 to $50,000 to support small food and farm businesses in selected states and counties, aiming to expand local and regional food markets, increase business acumen, and strengthen food systems in response to COVID-19, with projects to be completed within a year.

This ISO seeks solution summary and proposal submissions for projects that fall within the scope of the ARPA-H mission Resilient Systems Office (RSO). RSOs interest areas will address systemic challenges across the healthcare and public health landscape by investing in cutting-edge technologies that address long-standing gaps in the quality, efficacy, and consistent availability of care.Aspects of todays health and public health systems remain fragile due to systemic challenges, which include rising healthcare costs, inadequate healthcare coverage for significant populations, outdated infrastructure, and health disparities among different demographic groups. Acute challenges, such as hospital closures, supply chain disruptions, staffing shortages, cyber-attacks, public health crises, and the emergence of new diseases, further exacerbate existing fragilities, making it more difficult to maintain high standards of care. These challenges are compounded by the fact that systems remain fragmented, hindering the ability to gain comprehensive insights, make informed decisions, develop tailored interventions, and share critical health information between stakeholders.RSO seeks solution summaries and proposals that drive innovations to enhance the adaptability, reliability, and interoperability of the health ecosystem. Of interest are innovations that foster flexibility and enable adaptation to system stressors, so that people and systems remain well-positioned to deliver high-quality care and improve health outcomes. The following interest areas categorize the ground-breaking research we seek to support:Sociotechnical System Innovation: Innovate user-centric digital health tools, platforms, technologies, and intervention models that improve outcomes across the health continuum, including prevention, diagnosis, and treatment of physical, mental, and behavioral health. Approaches to build trust in the healthcare system and distribute high-quality health guidance in an understandable manner that improves patient outcomes. Novel real-time measurement tools to track health outcomes, evaluate post-market performance of new interventions, and enable convergence on the most effective strategies to improve the quality of care, especially for underserved communities. Other population centered innovations to create more resilient communities and subpopulations. Innovations might include aggregate improvements to quality of care and better physical, mental, and behavioral health outcomes for the health ecosystem.Health Ecosystem Integration: Novel ways to collect, protect, secure, integrate, analyze, communicate, and present health data, including but not limited to advances in privacy, cyber security, artificial intelligence with enhanced patient safety properties, low-code or no-code technologies, semantic approaches, and rapid integration techniques. Strategies and technologies to leverage homes, community centers, pharmacies, and other accessible locations to enable new modalities of high-quality care, expand the reach of clinical research, or integrate end-user feedback to rapidly iterate prototype designs. Approaches to strengthen the connectivity and interoperability of health data and devices to 5 enable the safe, secure, and seamless exchange of information among healthcare providers, researchers, and stakeholders. Other novel approaches to increase the interoperability of health-related systems in support of improved health outcomes and enhanced transparency across the health ecosystem.Adaptive Antifragile Solutions: Creative approaches to enhance the stability and dependability of the health ecosystem through new adaptive paradigms, methods that anticipate and mitigate disruptions before they occur, and enhancements to emergency response. Approaches that enable health infrastructure to rapidly integrate information from new sensors; create decision support tools; adapt supply chains, manufacturing, and logistics; and better leverage the workforce during public health emergencies. Novel methods to engineer resilient tissues, microbiomes, and biophysical systems to combat disease or maintain health. Other novel approaches to enhance adaptability and reduce fragility within the health ecosystem.Proposals are expected to use innovative approaches to enable revolutionary advances in science, technology, systems, or methodology. Specifically excluded are proposals that represent an evolutionary or incremental advance in the state of the art or technology that has reached the clinical trial stage. Additionally, proposals directed towards policy changes, traditional education and training, or center coordination, formation, or development, and construction of physical infrastructure are outside the scope of the ARPA-H mission

This funding opportunity provides financial support for innovative breast cancer research projects aimed at preventing the disease, understanding its recurrence, or improving treatment, targeting both early-stage and more developed studies from a range of eligible organizations and researchers.

**AMENDED on DECEMBER 11 2023**: The latest revision is posted as Amendment 18. Potential applicants are strongly encouraged to review the Amendment in its entirety, as it updates several sections. Specifically, ATTACHMENT 1: SPECIFIC TOPICS now includes Basic Research Topics N1-N4, with white papers due by 11:59pm EST on 5 February 2024. White papers may not be considered if they are received after this deadline. In addition, submissions to the general thrust areas in accordance with the requirements detailed in the BAA are also welcome. ** Please note that all correspondence must be sent to the appropriate Agency contact identified in Section 7. Agency Contacts. **

**CYCLE 4 POSTED ON 10 APRIL 2024. SEE ATTACHED UPDATED ANNOUNCEMENT FOR SPECIFIC TOPICS OF INTEREST IN CYCLE 4 AND SUBMISSION INFORMATION** **CYCLE 3, ORIGINALLY POSTED ON 21 MARCH 2023, IS UPDATED TO INCLUDE A QUESTION AND ANSWER DOCUMENT AND TO UPDATE THE SUBMISSION DATE TO 5 MAY 2023 BY 1700 EASTERN TIME** **CYCLE 3 POSTED ON 21 MARCH 2023. SEE ATTACHED UPDATED ANNOUNCEMENT FOR SPECIFIC TOPICS OF INTEREST IN CYCLE 3 AND SUBMISSION INFORMATION** **CYCLE 2 POSTED ON 8 FEBRUARY 2021. SEE ATTACHED UPDATED ANNOUNCEMENT FOR SPECIFIC TOPICS OF INTEREST IN CYCLE 2 AND SUBMISSION INFORMATION** Purpose: Future Army forces will need to conduct cross-domain maneuver (CDM) and at times, operate semi-independently, disbursed, and while communications and infrastructure such as Global Positioning System (GPS) are disrupted or denied. Robotics and Autonomous Systems (RAS) will play a key role in expanding the operational reach, situational awareness, and effectiveness of maneuver forces in CDM. The Combat Capabilities Development Command (CCDC) Army Research Laboratory (ARL) is focused on developing fundamental understanding and informing the art-of-the-possible for warfighter concepts through research to greatly improve air and ground based autonomous vehicle perception, learning, reasoning, communication, navigation, and physical capabilities to augment and increase the freedom of maneuver in complex and contested environments. The Scalable, Adaptive, and Resilient Autonomy (SARA) program is focused on developing and experimentally accelerating emerging research in autonomous mobility and maneuverability, scalable heterogeneous and collaborative behaviors, and human agent teaming to realize adaptive and resilient Intelligent Systems that can reason about the environment, work in distributed and collaborative heterogeneous teams, and make op-tempo decisions to enable Autonomous Maneuver in complex and contested environments. In order to achieve this vision, advancements are needed in following: Novel methods for all-terrain ground and aerial maneuver to interact with and move through complex environments. Methods for scalable and heterogeneous collaborative behaviors in support of collaborative air and ground manned-unmanned teaming operations. Techniques for improved perception, decision-making, and adaptive behaviors for fully autonomous maneuver in contested environments. Methods, metrics, and tools to facilitate, simulate, and enable testing and evaluation of emerging approaches for intelligent and autonomous systems under Army relevant constraints and environments Experimental testbeds to develop and refine knowledge products to inform and transition technology to Army stakeholders.

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This funding opportunity supports late-stage preclinical studies using adult stem cells to advance regenerative medicine therapies, specifically for researchers who have previously received NIH funding in this area.

This grant provides funding to small businesses developing innovative tools for bioenergy crop engineering to enhance sustainable energy production and reduce carbon emissions.

The Impact 100 Ozark grant program seeks to provide transformational grants to organizations serving eastern Christian County, Missouri. The foundation's mission is deeply aligned with this program, aiming to empower women to significantly improve community lives through generosity and by funding impactful grants. This strategic approach ensures that the grants have a lasting positive effect within the specified geographic area, reflecting Impact 100 Ozark's commitment to community betterment through focused financial support. The target beneficiaries for these grants are 501(c)3 organizations or other IRS-approved entities, including government entities, school districts, and churches, that specifically serve the eastern Christian County area. The primary impact goal is to fund significant initiatives that dramatically improve lives. While not explicitly stated as a "theory of change," the foundation's approach suggests that by empowering local organizations with substantial funding, they can address critical community needs and foster sustainable improvements. The program prioritizes proposals that avoid funding day-to-day operations, scholarships, or the start-up of new nonprofit agencies, indicating a focus on established organizations and projects with a clear, transformative scope. This ensures that the grants are directed towards initiatives that can create a significant, rather than incremental, impact. The available funding includes two grants totaling $49,000, with one grant of $35,000 and another of $14,000, underscoring the "significant grants" aspect of their mission. Expected outcomes and measurable results are inherent in the program's design, aiming for "lasting impact." While specific metrics are not detailed in the provided information, the emphasis on "transformational grants" implies a desire for substantial and demonstrable change within the community. The foundation's strategic priority is clearly to harness generosity to fund these impactful projects, thereby improving the lives of individuals and families in eastern Christian County.

This program provides early-stage life science startups nationwide with free mentorship, networking, and resources to help them grow and prepare for investment opportunities.

This grant provides funding opportunities for a wide range of organizations, including universities and businesses, to advance manufacturing technologies, with a particular encouragement for participation from historically black colleges and universities and minority institutions.

This program provides financial support to small businesses in Lancaster for purchasing essential equipment to help create jobs and boost local economic growth.

This funding opportunity is designed to support early career researchers in heliophysics, enabling them to conduct innovative studies related to the Sun and its interactions with the Earth and space environment.