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Grants for Small businesses - Science and Technology

Explore 1,384 grant opportunities

Fundamental Research to Counter Weapons of Mass Destruction
$500,000,000
U.S. Department of Defense - Defense Threat Reduction Agency
Federal

Application Deadline

Sep 30, 2024

Date Added

Feb 22, 2022

**AMENDED on DECEMBER 11 2023**: The latest revision is posted as Amendment 18. Potential applicants are strongly encouraged to review the Amendment in its entirety, as it updates several sections. Specifically, ATTACHMENT 1: SPECIFIC TOPICS now includes Basic Research Topics N1-N4, with white papers due by 11:59pm EST on 5 February 2024. White papers may not be considered if they are received after this deadline. In addition, submissions to the general thrust areas in accordance with the requirements detailed in the BAA are also welcome. ** Please note that all correspondence must be sent to the appropriate Agency contact identified in Section 7. Agency Contacts. **

Science and Technology
Public and State controlled institutions of higher education
InnovateMass
$350,000
Massachusetts Clean Energy Center
State

Application Deadline

Not specified

Date Added

Dec 10, 2024

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Energy
For profit organizations other than small businesses
Scalable, Adaptive, and Resilient Autonomy (SARA)
$2,500,000
DOD-AMC (Dept of the Army -- Materiel Command)
Federal

Application Deadline

May 10, 2024

Date Added

Apr 11, 2024

**CYCLE 4 POSTED ON 10 APRIL 2024. SEE ATTACHED UPDATED ANNOUNCEMENT FOR SPECIFIC TOPICS OF INTEREST IN CYCLE 4 AND SUBMISSION INFORMATION** **CYCLE 3, ORIGINALLY POSTED ON 21 MARCH 2023, IS UPDATED TO INCLUDE A QUESTION AND ANSWER DOCUMENT AND TO UPDATE THE SUBMISSION DATE TO 5 MAY 2023 BY 1700 EASTERN TIME** **CYCLE 3 POSTED ON 21 MARCH 2023. SEE ATTACHED UPDATED ANNOUNCEMENT FOR SPECIFIC TOPICS OF INTEREST IN CYCLE 3 AND SUBMISSION INFORMATION** **CYCLE 2 POSTED ON 8 FEBRUARY 2021. SEE ATTACHED UPDATED ANNOUNCEMENT FOR SPECIFIC TOPICS OF INTEREST IN CYCLE 2 AND SUBMISSION INFORMATION** Purpose: Future Army forces will need to conduct cross-domain maneuver (CDM) and at times, operate semi-independently, disbursed, and while communications and infrastructure such as Global Positioning System (GPS) are disrupted or denied. Robotics and Autonomous Systems (RAS) will play a key role in expanding the operational reach, situational awareness, and effectiveness of maneuver forces in CDM. The Combat Capabilities Development Command (CCDC) Army Research Laboratory (ARL) is focused on developing fundamental understanding and informing the art-of-the-possible for warfighter concepts through research to greatly improve air and ground based autonomous vehicle perception, learning, reasoning, communication, navigation, and physical capabilities to augment and increase the freedom of maneuver in complex and contested environments. The Scalable, Adaptive, and Resilient Autonomy (SARA) program is focused on developing and experimentally accelerating emerging research in autonomous mobility and maneuverability, scalable heterogeneous and collaborative behaviors, and human agent teaming to realize adaptive and resilient Intelligent Systems that can reason about the environment, work in distributed and collaborative heterogeneous teams, and make op-tempo decisions to enable Autonomous Maneuver in complex and contested environments. In order to achieve this vision, advancements are needed in following: Novel methods for all-terrain ground and aerial maneuver to interact with and move through complex environments. Methods for scalable and heterogeneous collaborative behaviors in support of collaborative air and ground manned-unmanned teaming operations. Techniques for improved perception, decision-making, and adaptive behaviors for fully autonomous maneuver in contested environments. Methods, metrics, and tools to facilitate, simulate, and enable testing and evaluation of emerging approaches for intelligent and autonomous systems under Army relevant constraints and environments Experimental testbeds to develop and refine knowledge products to inform and transition technology to Army stakeholders.

Science and Technology
Nonprofits
Economic Opportunity Holiday Grants
$5,000
Los Angeles County Department of Economic Opportunity
Local

Application Deadline

Not specified

Date Added

Dec 11, 2024

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Business and Commerce
Small businesses
Small Business Innovation Research Program (SBIR) Phase II
$287,500
U.S. Department of Health and Human Services (Administration for Community Living)
Federal

Application Deadline

Not specified

Date Added

Sep 8, 2025

This funding opportunity provides financial support to small businesses that have completed an initial research project, enabling them to develop innovative solutions that improve the lives of individuals with disabilities.

Science and Technology
Small businesses
Collaboration for Innovative Research on Aircraft Structure (CIRAS)
$6,000,000
U.S. Department of Defense (Air Force -- Research Lab)
Federal

Application Deadline

May 11, 2026

Date Added

May 11, 2021

This funding opportunity supports research and development projects focused on creating innovative and efficient aircraft structures, open to a wide range of applicants including universities, businesses, and non-profits.

Science and Technology
For profit organizations other than small businesses
Limited Competition: Regenerative Medicine Innovation Project (RMIP) Investigator-Initiated Studies (U01 Clinical Trial Not Allowed)
$400,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 21, 2025

Date Added

Jun 10, 2025

This funding opportunity supports late-stage preclinical studies using adult stem cells to advance regenerative medicine therapies, specifically for researchers who have previously received NIH funding in this area.

Health
State governments
Plant Engineering To Revolutionize Sustainable Energy Production And Heighten Opportunities For Novel Efficiency Sbir/STTR (Persephone Sbir/STTR)
$4,505,859
U.S. Department of Energy (Advanced Research Projects Agency Energy )
Federal

Application Deadline

Mar 4, 2025

Date Added

Jan 21, 2025

This grant provides funding to small businesses developing innovative tools for bioenergy crop engineering to enhance sustainable energy production and reduce carbon emissions.

Opportunity Zone Benefits
Small businesses
Business Improvement Grant Program
$10,000
Mayer Economic Development Authority
Private

Application Deadline

Jun 17, 2024

Date Added

Jun 11, 2024

The Impact 100 Ozark grant program seeks to provide transformational grants to organizations serving eastern Christian County, Missouri. The foundation's mission is deeply aligned with this program, aiming to empower women to significantly improve community lives through generosity and by funding impactful grants. This strategic approach ensures that the grants have a lasting positive effect within the specified geographic area, reflecting Impact 100 Ozark's commitment to community betterment through focused financial support. The target beneficiaries for these grants are 501(c)3 organizations or other IRS-approved entities, including government entities, school districts, and churches, that specifically serve the eastern Christian County area. The primary impact goal is to fund significant initiatives that dramatically improve lives. While not explicitly stated as a "theory of change," the foundation's approach suggests that by empowering local organizations with substantial funding, they can address critical community needs and foster sustainable improvements. The program prioritizes proposals that avoid funding day-to-day operations, scholarships, or the start-up of new nonprofit agencies, indicating a focus on established organizations and projects with a clear, transformative scope. This ensures that the grants are directed towards initiatives that can create a significant, rather than incremental, impact. The available funding includes two grants totaling $49,000, with one grant of $35,000 and another of $14,000, underscoring the "significant grants" aspect of their mission. Expected outcomes and measurable results are inherent in the program's design, aiming for "lasting impact." While specific metrics are not detailed in the provided information, the emphasis on "transformational grants" implies a desire for substantial and demonstrable change within the community. The foundation's strategic priority is clearly to harness generosity to fund these impactful projects, thereby improving the lives of individuals and families in eastern Christian County.

Business and Commerce
Small businesses
gBETA Life Sciences Accelerator for Early-stage Companies
Contact for amount
gener8tor
Private

Application Deadline

Not specified

Date Added

Feb 11, 2025

This program provides early-stage life science startups nationwide with free mentorship, networking, and resources to help them grow and prepare for investment opportunities.

Science and Technology
For profit organizations other than small businesses
Office of Naval Research Science and Technology for Advanced Manufacturing Projects (STAMP)
Contact for amount
U.S. Department of Defense (Office of Naval Research)
Federal

Application Deadline

Mar 31, 2025

Date Added

Mar 30, 2024

This grant provides funding opportunities for a wide range of organizations, including universities and businesses, to advance manufacturing technologies, with a particular encouragement for participation from historically black colleges and universities and minority institutions.

Science and Technology
Nonprofits
City of Lancaster Small Business Development Equipment Grant Program
$15,000
City of Lancaster
Local

Application Deadline

Jun 15, 2025

Date Added

May 12, 2025

This program provides financial support to small businesses in Lancaster for purchasing essential equipment to help create jobs and boost local economic growth.

Business and Commerce
Small businesses
ROSES 2024: B.14 Heliophysics Early Career Investigator Program
$175,000
National Aeronautics & Space Administration (NASA Headquarters)
Federal

Application Deadline

Dec 3, 2024

Date Added

Sep 25, 2024

This funding opportunity is designed to support early career researchers in heliophysics, enabling them to conduct innovative studies related to the Sun and its interactions with the Earth and space environment.

Science and Technology
Nonprofits
Innovation Incubator and Accelerator Grants
$100,000
City of Sacramento
Local

Application Deadline

Sep 9, 2024

Date Added

Aug 7, 2024

The City of Sacramento Office of Innovation and Economic Development is offering Incubator and Accelerator Grants to fund organizations that support start-up businesses and entrepreneurs in the Sacramento region. The program's mission aligns with stimulating economic development and fostering innovation by nurturing early-stage businesses. The grant size ranges from $10,000 to $100,000, with a total allocation of approximately $500,000, and a grant duration of one year. The deadline for applications is September 9, 2024. The target beneficiaries are early-stage businesses and entrepreneurs within the Sacramento region, particularly those with high growth potential and innovative solutions. The primary impact goal is for participants of the funded incubator and accelerator programs to successfully start or grow their businesses, thereby spurring innovation and stimulating economic development locally. Non-profits and companies are invited to apply for funding to run these programs. The grant prioritizes programs that offer a comprehensive suite of services, including mentorship and coaching from experienced professionals, educational workshops on business planning and financial management, product development support, and legal and administrative assistance. Furthermore, programs should focus on marketing and branding support, strategic partnerships, and facilitating access to funding through pitch training and investor introductions. Access to shared office space is also a valuable component. Expected outcomes include a measurable increase in the number of new businesses started and existing businesses grown within the Sacramento region. The program aims to foster a vibrant entrepreneurial ecosystem, leading to job creation and economic prosperity. The City's strategic priority is to invest in initiatives that directly contribute to innovation and economic growth, with the theory of change being that by supporting early-stage businesses through comprehensive programs, they will be better equipped to succeed and contribute to the local economy. Eligible activities for grant expenditures are broad, covering program development and delivery, staff salaries, stipends for volunteers and participants, training supplies, office space, marketing, and even food for participants (up to 5% of the grant total). Scholarships for program participants, software subscription fees, and professional services are also permissible. Applicants must operate from a fixed place of business within Sacramento city limits, or provide grant-supported programming within the city, and be in compliance with current and past City grants.

Workforce Development
Small businesses
Voucher Opportunity 6: Hydropower Testing Network (HyTN)
$250,000
U.S. Department of Energy
Federal

Application Deadline

Oct 30, 2024

Date Added

Sep 18, 2024

This program provides financial support to U.S.-based developers of hydropower technologies, enabling them to access testing facilities that will help improve their innovations and accelerate commercialization.

Energy
For profit organizations other than small businesses
COVID-19 PA Hazard Pay Grant
Contact for amount
Pennsylvania Department of Community and Economic Development
State

Application Deadline

Not specified

Date Added

Mar 22, 2024

The COVID-19 PA Hazard Pay Grant Program was established to help employers provide hazard pay to employees in life-sustaining occupations during the coronavirus (COVID-19) pandemic. Hazard pay is intended to keep front-line employees working in sectors that are vital to every Pennsylvanians’ existence. The program will help employers provide hazard pay for their employees to retain current employees. This reimbursement-based grant is for employers who will be offering hazard pay over the eligible program period. For general questions about the program or specific application questions, visit our Hazard Pay FAQs. Hazard Pay FAQs Financial Info: The COVID-19 PA Hazard Pay Grant Program was established to help employers provide hazard pay to employees in life-sustaining occupations during the coronavirus (COVID-19) pandemic. Hazard pay is intended to keep front-line employees working in sectors that are vital to every Pennsylvanians’ existence. The program will help employers provide hazard pay for their employees to retain current employees. This reimbursement-based grant is for employers who will be offering hazard pay over the eligible program period. For general questions about the program or specific application questions, visit our Hazard Pay FAQs. Hazard Pay FAQs

Health
Small businesses
AT&T Small Business Contest
$50,000
AT&T
Private

Application Deadline

Sep 30, 2025

Date Added

Jul 23, 2025

This contest provides financial support and promotional opportunities to small businesses in the U.S. with 50 or fewer employees, helping them grow and gain visibility through AT&T's network.

Business and Commerce
Small businesses
Advanced Development and Validation of Emerging Technologies for Basic and Clinical Cancer Research (R33 Clinical Trial Not Allowed)
$300,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Apr 10, 2026

Date Added

Sep 9, 2025

This funding opportunity supports the advanced development and validation of innovative technologies aimed at improving cancer research, targeting a diverse range of organizations capable of contributing to this field.

Health
State governments
Requests for Proposals for Financial Literacy Services Program
$500,000
City of Philadelphia
Local

Application Deadline

Not specified

Date Added

Sep 24, 2024

This funding opportunity provides financial support to nonprofit organizations in Philadelphia to deliver free tax preparation and financial literacy services to low-to-moderate income households, helping them build wealth and access essential financial resources.

Science and Technology
Small businesses
Disruptive DC Converters For Grid Resilient Infrastructure To Deliver Sustainable Energy Sbir/STTR (Dc-Grids Sbir/STTR)
$4,505,859
U.S. Department of Energy (Advanced Research Projects Agency Energy )
Federal

Application Deadline

Mar 3, 2025

Date Added

Nov 8, 2024

This funding opportunity provides financial support for small businesses and research institutions in the U.S. to develop innovative high-voltage direct current technologies that improve grid resilience and facilitate the integration of renewable energy sources.

Opportunity Zone Benefits
Small businesses