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Grants for Small businesses - Science and Technology

Explore 1,472 grant opportunities

Cellular Senescence Network (SenNet):Technology Projects (UG3/UH3 Clinical Trial Not Allowed)
$6,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Dec 9, 2025

Date Added

May 29, 2025

This funding opportunity supports a variety of organizations in developing innovative technologies to identify and target senescent cells, which could lead to new treatments for age-related diseases.

Health
State governments
2024 Dual Use Technology Development at Marshall Space Flight Center
$1,000,000
National Aeronautics & Space Administration
Federal

Application Deadline

Sep 30, 2024

Date Added

Dec 5, 2023

The 80MSFC24M0001 Cooperative Agreement Notice is a grant aimed at fostering partnerships with U.S. industry and academic/non-profit organizations to develop technologies that enhance the commercial space sector, support future NASA missions, and promote the U.S. as a leader in aeronautical and space science, with financial support provided by NASA.

Science and Technology
Independent school districts
HeartShare 2.0: Refining Heart Failure Subtypes and Treatment Targets for Personalized Clinical Trials - Clinical Trial Center and Clinical Centers (U01 Clinical Trial Optional)
$1,000,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Jul 9, 2026

Date Added

Sep 3, 2025

This funding opportunity provides financial support for academic institutions, nonprofit organizations, and other eligible entities to establish clinical trial centers focused on advancing research and treatment for heart failure with preserved ejection fraction through coordinated clinical trials and patient engagement.

Health
Public and State controlled institutions of higher education
ROSES 2025: C.8 Yearly Opportunities for Research in Planetary Defense
$1,500,000
National Aeronautics and Space Administration (NASA Headquarters)
Federal

Application Deadline

Dec 3, 2025

Date Added

Jul 15, 2025

This funding opportunity is designed to support U.S.-based researchers and institutions working on projects that enhance the detection, tracking, and mitigation of potentially hazardous asteroids and comets that could threaten Earth.

Science and Technology
Public and State controlled institutions of higher education
Engineer Research and Development Center (ERDC) - Construction Engineering Research Laboratory (CERL) - Commercial Solutions Opening (CSO)
Contact for amount
U.S. Department of Defense (Engineer Research and Development Center)
Federal

Application Deadline

Not specified

Date Added

Apr 30, 2025

This grant seeks innovative commercial solutions from a wide range of organizations to enhance military and civilian infrastructure, focusing on sustainability, energy efficiency, and advanced construction technologies.

Science and Technology
For profit organizations other than small businesses
Fiscal Year 2026 Phase II Continuation Consolidated Innovative Nuclear Research
$1,000,000
U.S. Department of Energy (Idaho Field Office)
Federal

Application Deadline

May 20, 2026

Date Added

Dec 16, 2025

This funding opportunity provides financial support to U.S. universities for advanced nuclear energy research projects that build on existing work, with an emphasis on collaboration and undergraduate involvement.

Energy
Public and State controlled institutions of higher education
Notice of Intent: $10.6 Million Funding Opportunity for Floating Offshore Wind Technology
$10,600,000
National Offshore Wind Research and Development Consortium (NOWRDC)
Private

Application Deadline

Not specified

Date Added

Jun 18, 2024

This funding opportunity provides $10.6 million for innovative projects that improve floating offshore wind technology, targeting advancements in port infrastructure, transmission systems, and environmental monitoring tools.

Energy
Nonprofits
Growing Rural Opportunities for Well-being (GROW) Regional Grants Program
$22,853,219
Indiana Department of Health (IDOH)
State

Application Deadline

Jul 1, 2026

Date Added

Mar 13, 2026

This program provides $600 million in funding to regional coalitions in Indiana's rural areas to improve health outcomes and access to care through community-driven initiatives.

Health
Nonprofits
Llama 3.1 Impact Grants
$500,000
Meta
Private

Application Deadline

Not specified

Date Added

Oct 17, 2024

This program provides funding to organizations worldwide for innovative projects that use an open-source AI model to address social challenges in areas like economic development and public services.

Community Development
Nonprofits
CMT Research Foundation Funding Program
$200,000
CMT Research Foundation
Private

Application Deadline

Not specified

Date Added

Oct 16, 2025

This funding program supports innovative research aimed at developing treatments and cures for Charcot-Marie-Tooth disease, welcoming proposals from a variety of global institutions, including academic centers and biotech companies.

Health
Nonprofits
CDBG COVID-19 Small Business Assistance Grant
$10,000
City of Danville
Local
Rolling

Application Deadline

Not specified

Date Added

Dec 7, 2023

CDBG COVID-19 Small Business Assistance Grant – Illinois: The City of Danville is offering up to $139,820 in funding through its Community Development Block Grant (CDBG) program, funded by the US Department of Housing and Urban Development (HUD), to support small businesses within the city in addressing the challenges posed by the COVID-19 pandemic. The grant aims to supplement existing federal or state programs and provide targeted assistance to help Danville businesses effectively navigate the impact of the pandemic.

Business and Commerce
Nonprofits
CoasterChase
$25,000,000
U.S. Department of Defense (DARPA - Biological Technologies Office)
Federal

Application Deadline

Aug 28, 2025

Date Added

Jun 27, 2025

This grant provides funding for innovative research to develop ingestible devices that can sense and stimulate the gut's nervous system to improve stress responses and enhance the performance of military personnel.

Science and Technology
Public and State controlled institutions of higher education
Native Plant - Section 6 - Segment 32
$20,000
Arizona Department of Agriculture (AZDA)
State

Application Deadline

Jul 31, 2026

Date Added

Jul 3, 2026

This grant provides funding to various organizations and entities in Arizona to support conservation efforts for rare and endangered plant species on non-federal lands.

Environment
State governments
DoD, Melanoma, Melanoma Academy Scholar Award
$2,640,000
U.S. Department of Defense (Dept. of the Army -- U.S.AMRAA)
Federal

Application Deadline

Aug 26, 2024

Date Added

May 9, 2024

Key aspects of the MASA: Principal Investigator: The PI (i.e., Scholar) must be an early-career researcher or physician-scientist no more than 7 years from obtaining their first faculty-level appointment. Postdoctoral fellows (and equivalent) are not eligible for this award mechanism. The PIs record of accomplishments and the proposed research will be evaluated regarding their potential for contributing to the FY24 MRP Focus Area(s) in Section II.A.1. Not all of the PIs accomplishments need to be in the field of melanoma. The PIs organization must demonstrate a commitment to the PI through confirmation of independent laboratory space. Impact: The impact of the proposed research must relate to at least one of the FY24 MRP Focus Areas in Section II.A.1. Impactful research, including basic research, should expedite the advancement of promising ideas towards clinical and/or public utility. The application must articulate the short- and long-term impact the proposed research will have on melanoma research and/or patient care. Career Development: A Career Development and Sustainment Plan (Attachment 7) is required and should be prepared with appropriate guidance from the Career Guide. The Career Development and Sustainment Plan should include a clearly articulated strategy for establishing collaborations and acquiring the necessary skills, competencies, and expertise to advance and sustain an independent career at the forefront of the melanoma field. The Scholar must show milestones and career pathways toward achieving the milestones. The Scholar must articulate commitment to interactions with the MA. Career Guide: The Scholar must designate a Career Guide. The Career Guide must be an experienced melanoma researcher, as demonstrated by a strong record of funding and publications in melanoma. In addition, the Career Guide must demonstrate a commitment to advancing the Scholars career in the melanoma field. The Career Guide must also be committed to fully participating in the MA throughout the award period of performance, including interacting with other MA Scholars and Career Guides and participating in MA activities (e.g., serving on the MA Advisory Board) as requested by MA Leadership. The Career Guide must not be the named Career Guide on any previously funded (FY21-FY23) MASA applications, nor may a Career Guide be named on more than ONE FY24 MASA application. Preliminary Data NOT Required: Preliminary data are not required. However, any unpublished, preliminary data presented should originate from the laboratory of the PI or a member of the research team.

Science and Technology
Nonprofits
DOD Glioblastoma, Resource Development Award
$500,000
U.S. Department of Defense (Dept. of the Army -- U.S.AMRAA)
Federal

Application Deadline

Nov 20, 2024

Date Added

Sep 17, 2024

This grant provides funding for researchers to develop and improve preclinical models that better mimic glioblastoma biology, with the goal of enhancing research and treatment outcomes for this aggressive brain cancer.

Science and Technology
Nonprofits
Rural Child Care Planning Program
$50,000
Iowa Economic Development Authority (IEDA)
State

Application Deadline

Aug 30, 2024

Date Added

Jul 11, 2024

The Walter F. Goodnough Trust offers grants specifically designed to support the rehabilitation of underprivileged disabled children, aligning its mission directly with improving the health and well-being of this vulnerable population. This core grant program focuses on a critical area of need within the healthcare sector for children facing both disability and financial hardship. The foundation supports this mission by funding hospitalization-based rehabilitation services exclusively within the state of Florida. The primary beneficiaries of this grant program are underprivileged disabled children in Florida who require hospitalization for rehabilitation. The overarching impact goal is to facilitate their recovery and improve their quality of life by providing essential financial support for necessary medical interventions. To achieve this, the trust prioritizes health-related programs and aims to ensure that eligible organizations, specifically 501(c)(3) exempt organizations, can access funding to serve these children effectively. Regarding expected outcomes and measurable results, the document notes that specific detailed metrics are not explicitly stated beyond the goal of "rehabilitation." However, the implicit outcome is an improvement in health and functional abilities for the children served. Success would likely be measured internally by proxies such as the number of children assisted, the types of rehabilitation services provided, and potentially the duration or effectiveness of their hospitalization and subsequent recovery. The foundation’s financial support is focused, with an average grant size ranging from $2,500 to $5,000 and an average total giving of $15,000 per year, suggesting a focus on supporting individual or smaller-scale rehabilitation projects. The foundation's strategic priorities are centered on creating a direct and measurable impact within Florida's healthcare landscape, particularly for disabled children. This focused approach is highlighted by the geographic limitation to Florida and the specific program area of Health. The trust's theory of change posits that by providing financial grants directly to qualified organizations, they can enable access to crucial rehabilitation services that would otherwise be out of reach for underprivileged families, thereby addressing a core financial barrier to recovery and improved quality of life.

Workforce Development
City or township governments
Cecil County Route 40 Business Revitalization Program 2025
$25,000
Cecil County
Local

Application Deadline

May 1, 2025

Date Added

Nov 22, 2024

This funding initiative provides financial support to businesses and organizations along the Route 40 corridor in Cecil County, Maryland, for exterior improvements and revitalization efforts, with a special focus on removing blighted structures.

Science and Technology
For profit organizations other than small businesses
RFA C-25.1 Texas Diagnostic and Devices Company Awards
Contact for amount
Cancer Prevention and Research Institute of Texas
State

Application Deadline

May 1, 2024

Date Added

Apr 18, 2024

Funding available through this RFA supports the ongoing research and development of diagnostic tests and devices to treat, detect, diagnose, monitor, and assist in the treatment of cancer. Relevant areas include: Devices and assays for cancer detection, diagnosis, prognosis, monitoring, treatment and prediction of response or resistance to treatment Markers for cancer prevention and control, companion diagnostic to a therapy Development of diagnostic tests to distinguish high-risk early lesions Generally, at the time that an applicant applies to CPRIT pursuant to this RFA, the company has developed a commercial prototype of the device or a pictorial representation of the functional components/elements of the device. With respect to diagnostics, the company has developed assays that work on human samples and whose importance is well justified for development into clinical assays. The applicant should be working toward submitting an Investigational Device Exemption (IDE) or a 510(k) or Premarketing Approval (PMA) and is typically within one year from filing an IDE (or later stage work.) Potential applicants that are not at or near this stage of product development should consider applying for a Texas Seed Company Award. With appropriate justification, companies may use CPRIT funds to support studies that establish preclinical proof of concept, product validation, design, production, manufacturing and development, and clinical studies demonstrating safety and efficacy.

Business and Commerce
Small businesses
EDA Small Business Incentive Grant 2025
Contact for amount
New Ulm Economic Development Authority (EDA)
State

Application Deadline

Not specified

Date Added

Dec 17, 2024

This grant provides financial support to small businesses in New Ulm, particularly in the restaurant, retail, childcare, and light manufacturing sectors, to promote local economic development.

Workforce Development
Small businesses
Rural Dental Efficiency and Access Grants
$10,000,000
Wisconsin Department of Health Services (DHS)
State

Application Deadline

Jul 27, 2026

Date Added

Jun 16, 2026

This funding opportunity provides financial support to dental providers in rural Wisconsin to adopt modern technologies that improve efficiency and access to care for underserved populations.

Health
Nonprofits