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Grants for Small businesses - Science and Technology

Explore 1,472 grant opportunities

Pilot Projects Enhancing Utility and Usage of Common Fund Data Sets (R03 Clinical Trial Not Allowed)
$200,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 23, 2026

Date Added

Jul 1, 2025

This funding opportunity provides financial support for small research projects that enhance the use and accessibility of large biomedical datasets, encouraging innovative analysis and integration to drive new discoveries in health research.

Science and Technology
Public and State controlled institutions of higher education
Complement-ARIE NAMs Reduction to Practice Challenge
$1,000,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Dec 24, 2025

This grant provides funding to researchers and organizations developing innovative non-animal testing methods to improve biomedical research and safety assessments.

Science and Technology
Individuals
Young Faculty Award (YFA) 2026
$1,350,000
U.S. Department of Defense (DARPA - Defense Sciences Office)
Federal

Application Deadline

Not specified

Date Added

Oct 1, 2025

This program provides funding and mentorship to early-career U.S. faculty researchers to develop innovative technologies that address national security challenges.

Science and Technology
Public and State controlled institutions of higher education
ROSES 2024: A.45 Earth Action: Ecological Conservation Impact Assessment
$500,000
NASA-HQ (NASA Headquarters)
Federal

Application Deadline

May 15, 2024

Date Added

Feb 15, 2024

Please note that this program requests optional Notices of Intent, which are due via NSPIRES by April 15, 2024. See the full posting on NSPIRES for details. Proposers must retrieve the instructions document (zip file) associated with the application package for this opportunity as there is at least one required form that must be attached to the submitted proposal package. The National Aeronautics and Space Administration (NASA) Science Mission Directorate (SMD) released its annual omnibus Research Announcement (NRA), Research Opportunities in Space and Earth Sciences (ROSES) 2024 (OMB Approval Number 2700-0092, CFDA Number 43.001) on February 14, 2024. In this case "omnibus" means that this NRA has many individual program elements, each with its own due dates and topics. All together these cover the wide range of basic and applied supporting research and technology in space and Earth sciences supported by SMD. Awards will be made as grants, cooperative agreements, contracts, and inter- or intra-agency transfers, depending on the nature of the work proposed, the proposing organization, and/or program requirements. However, most extramural research awards deriving from ROSES will be grants, and many program elements of ROSES specifically exclude contracts, because contracts would not be appropriate for the nature of the work solicited. The typical period of performance for an award is three years, but some programs may allow up to five years and others specify shorter periods. In most cases, organizations of every type, Government and private, for profit and not-for-profit, domestic and foreign (with some caveats), may submit proposals without restriction on teaming arrangements. Tables listing the program elements and due dates (Tables 2 and 3), a table that provides a very top level summary of proposal contents (Table 1), and the full text of the ROSES-2024 "Summary of Solicitation", may all be found NSPIRES at http://solicitation.nasaprs.com/ROSES2024. This synopsis is associated with one of the individual program elements within ROSES, but this is a generic summary that is posted for all ROSES elements. For specific information on this particular program element download and read the PDF of the text of this program element by going to Tables 2 or 3 of this NRA at http://solicitation.nasaprs.com/ROSES2024table2 and http://solicitation.nasaprs.com/ROSES2024table3, respectively, click the title of the program element of interest, a hypertext link will take you to a page for that particular program element. On that page, on the right side under "Announcement Documents" the link on the bottom will be to the PDF of the text of the call for proposals. For example, if one were interested in The Lunar Data Analysis Program (NNH24ZDA001N-LDAP) one would follow the link to the NSPIRES page for that program element and then to read the text of the call one would click on C.8 Lunar Data Analysis Program (.pdf) to download the text of the call. If one wanted to set it into the context of the goals, objectives and know the default rules for all elements within Appendix C, the planetary science division, one might download and read C.1 Planetary Science Research Program Overview (.pdf) from that same page. While the letters and numbers are different for each element within ROSES (A.12, B.7, etc.) the basic configuration is always the same, e.g., the letter indicates the Science Division (A is Earth Science, B is Heliophysics etc.) and whatever the letter, #1 is always the division overview. Frequently asked questions for ROSES are posted at http://science.nasa.gov/researchers/sara/faqs. Questions concerning general ROSES-2024 policies and procedures may be directed to Max Bernstein, Lead for Research, Science Mission Directorate, at sara@nasa.gov, but technical questions concerning specific program elements should be directed to the point(s) of contact for that particular element, who may be found either at the end of the individual program element in the summary table of key information or on the web list of topics and points of contact at: http://science.nasa.gov/researchers/sara/program-officers-list. Not all program elements are known at the time of the release of ROSES. To be informed of new program elements or amendments to this NRA, proposers may subscribe to: (1) The SMD mailing lists (by logging in at http://nspires.nasaprs.com and checking the appropriate boxes under "Account Management" and "Email Subscriptions"), (2) The ROSES-2024 blog feed for amendments, clarifications, and corrections to at https://science.nasa.gov/researchers/solicitations/roses-2024/, and (3) The ROSES-2024 due date Google calendars (one for each science division). Instructions are at https://science.nasa.gov/researchers/sara/library-and-useful-links (link from the words due date calendar).

Science and Technology
Nonprofits
NIJ FY25 Research and Evaluation of Policing Practices
$5,000,000
U.S. Department of Justice (National Institute of Justice)
Federal

Application Deadline

Jun 9, 2026

Date Added

May 8, 2026

This funding opportunity provides financial support for research and evaluation projects aimed at improving policing practices, officer well-being, and public safety outcomes across various law enforcement agencies in the United States.

Law Justice and Legal Services
State governments
Harmful Algal Bloom Innovation Challenge: Toxin Detection in Seafood
$250,000
U.S. Department of Commerce (DOC NOAA - ERA Production)
Federal

Application Deadline

Jul 16, 2026

Date Added

Mar 16, 2026

This funding opportunity provides financial support for U.S. institutions and organizations to develop innovative and cost-effective technologies for detecting harmful algal bloom toxins in seafood, enhancing public health and seafood safety.

Environment
Nonprofits
DOD Parkinsons Early Investigator Research Award
$2,400,000
U.S. Department of Defense - Dept. of the Army -- U.S.AMRAA
Federal

Application Deadline

Aug 6, 2024

Date Added

May 8, 2024

The PRP EIRA supports research opportunities for investigators in the early stages of their careers. The Early Investigator is considered the Principal Investigator (PI) of the application and must exhibit strong potential for, and commitment to, pursuing a career as an investigator at the forefront of PD research; however, the PI is not required to have previous PD research experience.

Science and Technology
Nonprofits
DoD Tuberous Sclerosis Complex, Idea Development Award
$500,000
U.S. Department of Defense - Dept. of the Army -- U.S.AMRAA
Federal

Application Deadline

Aug 1, 2024

Date Added

Apr 22, 2024

The IDA promotes ideas that have the potential to yield high-impact findings and new avenues of investigation. This award mechanism supports conceptually innovative research that could ultimately lead to critical discoveries in TSC research and/or improvements in patient care. Research projects should include a well-formulated, testable hypothesis based on strong preliminary data and scientific rationale. The following are important aspects of the IDA: Impact: Applications should articulate both the short- and long-term impact of the proposed research. High-impact research will, if successful, significantly advance TSC research and/or patient care. Innovation: Innovative research may introduce a new paradigm, challenge existing paradigms, look at existing problems from new perspectives, or exhibit other uniquely creative qualities that may include high-risk/potentially high-gain approaches to TSC research. Research that is merely an incremental advance (to the next logical step) is not considered innovative. Preliminary Data: Unpublished results from the laboratory of the Principal Investigator (PI) or collaborators named on this application, and/or data from the published literature that are relevant to TSC and the proposed research project, are required. New-to-the-Field Investigator (NFI): The FY24 TSCRP IDA mechanism encourages applications from investigators in the early stages of their TSC research career. The NFI Option is designed to support the continued development of promising independent investigators that are early in their faculty appointments and/or the transition of established investigators from other research fields into TSC research. Applications to the NFI Option will compete separately from Established Investigators submitting to the regular IDA. PIs applying under the NFI category are strongly encouraged to strengthen their applications through collaboration with investigators experienced in TSC research and/or possessing other relevant expertise as demonstrated by a record of funding and publications. See Attachment 8: Eligibility Statement.

Science and Technology
Nonprofits
Preventing Outages and Enhancing the Resilience of the Electric Grid Formula Grants to States
$150,000,000
Texas Division of Emergency Management
State

Application Deadline

Jun 28, 2024

Date Added

May 2, 2024

Governor Greg Abbott and the Texas Division of Emergency Management (TDEM) have announced the opening of applications for the Department of Energy's (DOE) grant program aimed at enhancing the resilience of electric grids against disruptive events. The program is designed to allocate competitive grants to improve infrastructure and reduce the likelihood and impact of such events on the electrical grid. The grant supports weatherization, fire-resistant technologies, monitoring and control systems, vegetation management, adaptive protections, and advanced modeling technologies. This grant opportunity is now active with a closing deadline of June 28, 2024.

Energy
City or township governments
ROSES25: C.12 Foundational Artificial Intelligence for the Moon and Mars
Contact for amount
National Aeronautics and Space Administration (NASA Headquarters)
Federal

Application Deadline

Apr 28, 2026

Date Added

Jan 14, 2026

This funding opportunity supports research and development in artificial intelligence technologies to advance NASA's exploration and scientific missions on the Moon and Mars, targeting U.S.-based institutions and international collaborations.

Science and Technology
Public and State controlled institutions of higher education
FY 2025 NIST Small Business Innovation Research Program Phase I
$100,000
U.S. Department of Commerce (National Institute of Standards and Technology)
Federal

Application Deadline

Dec 27, 2024

Date Added

Oct 30, 2024

This grant provides funding to small businesses for innovative research projects that can be commercialized, particularly those addressing federal agencies' research needs and promoting participation from underrepresented groups.

Science and Technology
Small businesses
2024/25 Effectiveness Monitoring Committee Grant
$973,392
California Board of Forestry
State

Application Deadline

May 15, 2024

Date Added

Apr 2, 2024

The Effectiveness Monitoring Committee (EMC), serving as an advisory body to the Board of Forestry and Fire Protection, aims to fund scientific research that tests the effectiveness of the California Forest Practice Rules and associated regulations. This includes addressing natural resource issues such as watershed science, wildlife concerns, and wildfire hazard. Proposals are sought that focus on one or more of EMC's Research Themes and Critical Monitoring Questions, particularly those that contribute to understanding and enhancing wildfire resilience and response to climate change across California's forestlands. Projects must directly relate to management activities on private timberlands in the state, although those on public lands may qualify if they demonstrate relevance to non-federal timberland activities.

Environment
Small businesses
Energy Storage Technology And Product Development
$2,000,000
New York State Energy Research and Development Authority
State

Application Deadline

Aug 11, 2025

Date Added

Jul 15, 2025

This funding opportunity provides financial support for innovative energy storage technology development and demonstration projects in New York State, targeting organizations capable of advancing next-generation storage solutions.

Energy
For profit organizations other than small businesses
Fiscal Year 2026 University Reactor Sharing and Outreach
$200,000
U.S. Department of Energy (Idaho Field Office)
Federal

Application Deadline

Feb 27, 2026

Date Added

Jan 7, 2026

This funding opportunity provides financial support to U.S. universities with operational nuclear research reactors to promote collaboration, education, and public engagement in nuclear science and engineering.

Education
Public and State controlled institutions of higher education
Community Development Block Grant Program 2025
$1,873,363
County of Maui
Local

Application Deadline

Not specified

Date Added

Oct 24, 2024

This program provides flexible funding to local governments to improve housing, infrastructure, and economic opportunities for low- and moderate-income individuals in their communities.

Community Development
Nonprofits
Agriculture Grant
$10,000
Orange County Agricultural Economic Development
Local

Application Deadline

Not specified

Date Added

Dec 17, 2024

This program provides financial assistance to farmers in Orange County, North Carolina, to support innovative agricultural projects that enhance income and market access.

Agriculture
Small businesses
FY 2026 Implementation of the U.S. Integrated Ocean Observing System (IOOS)
$5,000,000
U.S. Department of Commerce (DOC NOAA - ERA Production)
Federal

Application Deadline

Apr 13, 2026

Date Added

Feb 11, 2026

This funding opportunity provides financial support to universities, non-profits, and government entities for developing and managing regional coastal observing systems that enhance ocean and Great Lakes data collection and decision-making.

Environment
Public and State controlled institutions of higher education
Decentralized Artificial Intelligence through Controlled Emergence (DICE)
Contact for amount
U.S. Department of Defense (DARPA - Information Processing Technologies Office)
Federal

Application Deadline

Aug 25, 2026

Date Added

Jun 11, 2026

This funding opportunity is designed to support innovative research in decentralized artificial intelligence systems that can autonomously coordinate and adapt in complex and challenging environments, targeting a wide range of researchers and organizations capable of advancing national security technologies.

Science and Technology
Nonprofits
ROSES 2024: C.7 New Frontiers Data Analysis Program
$2,500,000
National Aeronautics & Space Administration (NASA Headquarters)
Federal

Application Deadline

Nov 7, 2024

Date Added

Sep 24, 2024

This funding opportunity is designed to support researchers and organizations engaged in innovative data analysis related to space and Earth sciences, enabling advancements in scientific understanding and technology development.

Science and Technology
Nonprofits
DoD Peer Reviewed Medical Research Program, Technology/Therapeutic Development Award
$3,500,000
U.S. Department of Defense (Dept. of the Army -- U.S.AMRAA)
Federal

Application Deadline

Jul 21, 2025

Date Added

May 28, 2025

This funding opportunity supports researchers and organizations in developing innovative medical solutions to improve the health and well-being of military personnel, veterans, and their families.

Science and Technology
Nonprofits