Grants for Small businesses - Science and Technology

This funding opportunity is designed to support innovative prototype projects in military and civil engineering, targeting nontraditional defense contractors, traditional defense contractors, and nonprofit research institutions.

This grant provides funding to small businesses in the U.S. to develop innovative technologies that address critical national needs, particularly in health and technology, while promoting collaboration with research institutions.

This funding opportunity provides financial support for nonprofits, public-private partnerships, and industry consortia in North Dakota to develop and implement innovative autonomous agriculture projects that enhance technology, infrastructure, and workforce systems in the state.

Funding available through this RFA supports the ongoing research and development of innovative products, services, and infrastructure with significant potential impact on patient care. Generally, at this stage, the company has identified and characterized a lead compound; demonstrated efficacy in multiple translationally relevant animal models; completed pilot/dose ranging toxicology studies; determined the feasibility of a scalable, GMP compliant manufacturing process, including release assays; and identified a prototype formulation suitable for further development. The applicant is typically within one year from filing an IND/IDE or already in Phase 1. With appropriate justification, companies may use CPRIT funds to support the following: Studies that establish preclinical proof of concept (safety and efficacy) CMC/manufacturing development GLP safety studies to support INDs Phase 1 in humans to establish safety and a recommended dose for phase 2 Phase 2 studies to determine safety and efficacy in initial targeted patient population

This grant provides funding and technical support to innovators and organizations developing sustainable solutions for reusing and repurposing end-of-life products, promoting a circular economy and reducing waste.

This funding opportunity supports innovative research projects aimed at improving the quality of life for individuals living with lupus, including Service Members, Veterans, and their families, by encouraging collaboration among researchers, clinicians, and lupus advocates.

This grant provides funding for research projects that improve the production, quality, and marketability of iceberg lettuce in Arizona, targeting researchers and agricultural institutions involved in the lettuce industry.

The United States is made up of regional systems comprising interdependent urban and rural systems and every community category between urban and rural. Urban systems and rural systems are interdependent for the provisioning of food, energy sources, water, other materials and natural resources, markets, manufactured goods, and medical resources. These systems are also connected by ecological processes that both influence and are influenced by human behavior. The vital interconnection of urban-rural systems underscores the critical need for the advancement of sustainable regional systems (SRS). The goal of this solicitation is to fund convergent research and education that will advance sustainable regional systems science, engineering, and education to facilitate the transformation of current regional systems to enhance sustainability. To further the advancement of SRS science, engineering, and education, NSF will support proposals for Sustainable Regional Systems Research Networks (SRS RNs). Sustainable regional systems are connected urban and rural systems that are transforming their structures and processes collaboratively with the goal of measurably and equitably advancing the well-being of people and the planet. The purpose of the SRS RNs competition is to develop and support interdisciplinary, multi-organizational teams working collaboratively to produce cutting-edge convergent research, education, and outreach that addresses grand challenges in sustainable regional systems. SRS RNs will study multiscale regional systems to further SRS science, engineering, and education. Key elements will include new data, methods, and models to understand interactions between natural, human-built, and social systems; improved understanding of interdependencies, mutual benefits, and trade-offs of different wellbeing outcomes for humans and the environment; new and generalizable theories of change relevant to SRS;theco-production of knowledge; andexploration of conceptsof social equity in sustainable regional systems across spatial and temporal scales. SRS RN outcomes will have the potential to inform societal actions for sustainability across urban systems and the connected rural communities that make up regional systems. Subject to availability of funds and quality of proposals, this SRS RN solicitation will support: SRS RN Awards.These awards will supportfundamental convergent research, education, and outreach that addressesengineering, chemistry, biology, geosciences, mathematics, statistics, environmental, data, computational, education, and social, behavioral, and economic sciences ofsustainable regional systems in partnerships thatmay embrace universities, colleges, federal, state, and local governments, tribal communities, non-governmental and international bodies, non-profit organizations, industry, practitioners, and other community groups. The award size is up to $15 million totalwith a duration of 5 years. SRS RNs will conduct innovative and pioneering fundamental research and education that is of a scale and complexity that would not be possible within a single organization, center, or through the normal collaborative modes of NSF research support in core programs.

This funding opportunity supports the development of innovative computational tools to analyze complex brain data, inviting a diverse range of researchers and organizations to enhance our understanding of neural circuits and their functions.

The DoD Peer Reviewed Cancer, Virtual Cancer Center Director Award is a funding opportunity for established cancer researchers to create and lead a virtual cancer center, which aims to foster collaboration, mentorship, and innovative research among early career investigators across different cancer disciplines, with a focus on convergent science and the development of collaborative seed projects.

This funding opportunity supports research and extension projects that promote the development and adoption of nontraditional crops, helping farmers diversify their operations and improve economic resilience across the United States.

This funding opportunity provides financial support for researchers developing innovative chemical probes to study biological processes in the nervous system, focusing on understanding brain function and neurological diseases.

The Food Safety Education Fund grants program, administered by the Michigan Department of Agriculture & Rural Development (MDARD), is designed to enhance food safety throughout Michigan. Funded by assessments on licensed food establishments, the program aligns with a mission to protect public health by providing critical food safety training and education. This initiative directly supports the broader goal of ensuring a safe food supply for all Michigan residents. The foundation's strategic priority is to prevent foodborne illness through proactive education and the empowerment of various stakeholders within the food system. The program primarily targets two key beneficiary groups: Michigan consumers and food service establishment employees, as well as agents of the director who enforce food regulations (e.g., local health department sanitarians and MDARD food safety inspectors). The impact goal is to improve food safety knowledge and practices among these groups, ultimately reducing the incidence of foodborne illnesses. Eligibility is restricted to Michigan governmental and non-profit organizations and entities, ensuring that the grants support organizations deeply embedded in community health and public service. Producers, marketers, processors, and growers are explicitly excluded to maintain the program's focus on education and training. For the 2024-2025 grant cycle, up to $365,600 is available, with a specific allocation of $242,500 for consumer food safety education and $114,100 for food service establishment employees and regulatory agents. This demonstrates a clear prioritization of widespread public education while also fortifying the knowledge base of those directly involved in food handling and enforcement. The grant duration is typically one year, though multi-year proposals are considered on an individual basis, contingent on future funding availability. Proposals should specifically avoid requesting funding for routine or required training, such as HACCP or ServSafe certification, emphasizing a focus on innovative and supplementary educational initiatives. Proposals are evaluated based on several key criteria, including goals and objectives to improve food safety, assessment of statewide need and audience, measurable outcomes, potential for partnering with other organizations, inclusion of matching funds, and opportunities to build upon previously funded projects. These selection criteria reflect the program's theory of change, which posits that strategic partnerships, evidence-based interventions, and quantifiable results are essential for achieving sustainable improvements in food safety. The expected outcomes include a more informed public, better-trained food service professionals, and more effective enforcement of food safety regulations, all contributing to a safer food environment across Michigan.

The Geothermal Resources’ Value in Implementing Decarbonization (GRID) FOA aims to advance the Biden-Harris Administration's goals for a carbon-pollution-free electricity sector by 2035 and a net-zero emissions economy by 2050. The program focuses on regional grid modeling studies to quantify geothermal power's potential contribution to a decarbonized grid. Eligible applicants must submit a Letter of Intent by July 24th, 2024, and full applications by September 9th, 2024. The program offers funding between $500,000 and $1,500,000, with an estimated total funding of approximately $7 million.

This funding opportunity supports researchers in developing practical medical solutions that improve health outcomes for military service members, veterans, and their families by translating scientific discoveries into clinical applications.

This funding initiative provides financial support to small businesses in Overland Park, Kansas, to enhance their operations and workforce through various improvement projects.

This funding opportunity provides financial support for organizations to develop ethical technology initiatives that promote human rights and counter authoritarian influences globally.

This funding opportunity supports innovative researchers exploring groundbreaking ideas in tuberous sclerosis complex, aiming to generate preliminary data for future studies that benefit service members, veterans, and the public.

This funding opportunity provides financial support to Pennsylvania farmers, agricultural processors, and service providers for adopting innovative technologies and sustainable practices to improve productivity and environmental stewardship.

The FY24 DMDRP IDA promotes new ideas that are still in the early stages of development and have the potential to yield impactful data and new avenues of investigation. This award supports conceptually innovative, high-risk/high-reward research that could lead to critical discoveries or major advancements that will accelerate progress in improving outcomes for individuals with DMD. Applications should include a well-formulated, testable hypothesis based on strong scientific rationale.New Investigators: The FY24 DMDRP IDA mechanism encourages applications from independent investigators in the early stages of their careers (i.e., within 10 years of their first faculty appointment or equivalent) or applications from established investigators new to DMD research.The New Investigator Early Stage category is designed to allow applicants early in their faculty appointments to compete for funding separately from established investigators.The New Investigator Transitioning category is designed to allow investigators in an area other than muscular dystrophy, at or above the level of Assistant Professor, seeking to transition to a career in DMD, thereby bringing their expertise to the field.Applications from New Investigators and Established Investigators will be peer and programmatically reviewed separately. Principal Investigators (PIs) using the New Investigator Early Stage category or New Investigator Transitioning category are strongly encouraged to strengthen their applications by collaborating with investigators experienced in DMD research and/or possessing other relevant expertise. It is the responsibility of the applicant to describe how the included collaboration will augment the PIs expertise to best address the research question. All applicants for the New Investigator categories must meet the specific eligibility criteria described in Section II.C, Eligibility Information.Preliminary data relevant to DMD that supports the feasibility of the research hypotheses and research approaches are required. Preliminary data may include unpublished results from the laboratory of the PI, research team or collaborators named on the application.Key elements of this award are as follows:Innovation: Research deemed innovative may introduce a new paradigm, challenge current paradigms, look at existing problems from new perspectives, or exhibit other uniquely creative qualities.Impact: Research that has high potential impact may lead to major advancements and significantly accelerate progress toward improving outcomes for individuals with DMD.It is the responsibility of the PI to clearly and explicitly articulate the projects innovation and its potential impact on DMD. The projects impact to both DMD research and to individuals with DMD should be articulated, even if clinical impact is not an immediate outcome. Applications that demonstrate exceptional scientific merit but lack innovation and high potential impact do not meet the intent of the IDA.Clinical trials are not allowed under this funding opportunity.A clinical trial is defined in 45 CFR 46.102 as a research study in which one or more human subjects are prospectively assigned to one or more interventions (which may include a placebo or another control) to evaluate the effects of the interventions on biomedical or behavioral health-related outcomes.Studies that do not seek to measure safety, effectiveness, and/or efficacy outcome(s) of an intervention are not considered clinical trials.For the purposes of this funding opportunity, research that meets the definition of a clinical trial is distinct from clinical research. Clinical research encompasses research with human data, human specimens, and/or interaction with human subjects. Clinical research is observational in nature and includes:(1) Research conducted with human subjects and/or material of human origin such as data, specimens, and cognitive phenomena for which an investigator (or co-investigator) does not seek to assess the safety, effectiveness, and/or efficacy outcomes of an intervention. Research meeting this definition may include but is not limited to: (a) mechanisms of human disease, (b) diagnostic or detection studies (e.g., biomarker or imaging), (c) health disparity studies, and (d) development of new technologies.(2) Epidemiologic and behavioral studies that do not seek to assess the safety, effectiveness, and/or efficacy outcomes of an intervention.(3) Outcomes research and health services research that do not fit under the definition of clinical trial.Excluded from the definition of clinical research are in vitro studies that utilize human data or specimens that cannot be linked to a living individual and meet the requirements for exemption under 46.104(d)(4) of the Common Rule.