Science and Technology Grants

The City of Dunedin is currently accepting funding requests for its 2025 Aid to Social/Cultural Non-Profit Organizations program. This grant initiative is designed to support non-profit programs that provide broad benefits to the community and for which other City of Dunedin funding sources are not available. The program's mission aligns with enhancing community well-being by fostering social and cultural initiatives, demonstrating the City's commitment to supporting vital community services and enriching the lives of its residents through diverse programming. The target beneficiaries of this grant are the community as a whole, with a focus on programs from social/cultural non-profit organizations. The impact goal is to address specific community needs through various programs. The City of Dunedin emphasizes the importance of these organizations in contributing to the overall social and cultural landscape, ensuring that funding is directed towards initiatives that have a wide-reaching and positive effect on the population. Priority for funding will be given to programs that clearly demonstrate a benefit to the community as a whole and do not have alternative funding from the City. Organizations must submit a letter detailing the requested funding amount and justification, the specific community needs their programs address, how the funding will be utilized (e.g., personnel, operating, or capital costs), and the performance criteria for measuring community value. This structured approach ensures accountability and strategic allocation of resources. For organizations that received funding in FY 2024, a crucial requirement for eligibility is the submission of documentation illustrating the achievement of their FY 2024 public benefits and performance measures. This demonstrates the City's strategic priority on measurable results and accountability, aligning with a theory of change that effective funding leads to tangible community improvements. The expected outcomes are impactful social and cultural programs that are well-managed and deliver demonstrable value to the community.

The Black Equity & Excellence Fund, established by the Central New York Community Foundation, is dedicated to supporting community-based projects that foster self-sufficiency and enhance the physical and economic well-being of the Black community in Central New York. This initiative aligns with the Foundation's broader mission to strengthen race-related matters and promote social and educational growth within the community. By investing in projects that directly address the unique needs and challenges faced by Black residents, the fund aims to create a more equitable and thriving environment, reflecting the Foundation's strategic priority of community development and social justice. The primary beneficiaries of this grant program are organizations and projects that explicitly serve the Black community, particularly in Onondaga and Madison counties. The overarching impact goal is to improve the quality of life for Black individuals and families through various interventions. The program aims to empower the Black community by building upon existing capabilities and addressing systemic disparities. This is achieved by focusing on specific interest areas that have been identified as crucial for community advancement and well-being. The fund prioritizes projects within several key focus areas, including Black Creatives, Black Leadership + Advancement, Black LGBTQIA+, Black Mental Wellness, Black Legacy + Generational Wealth, Black Business, Black Maternal Health, Black Civic Engagement, Black Youth + Students, and Black Tech. These areas reflect the Foundation's theory of change, which posits that targeted investments in these sectors will lead to holistic development and greater equity. Projects are encouraged to contribute to dialogue that strengthens race-related matters and supports social and educational growth, indicating a strategic approach to fostering long-term, sustainable change. Expected outcomes include increased self-sufficiency, improved physical and economic conditions, and enhanced community well-being within the Black community. Measurable results are tied to the types of projects funded, with different funding levels supporting various initiatives, from grassroots efforts and pilot programs to the expansion of existing projects and large capital projects. The eligibility criteria, which mandate Black leadership in senior executive positions and at least 51% Black board membership, further ensure that the projects are community-led and responsive to the needs of the Black population, thereby maximizing impact and fostering authentic community empowerment.

The key aspects of this award are: Impact: The SRA is intended to support research designed to have a major impact on the health and well-being of melanoma survivors, their families, and/or caregivers. Impactful research will accelerate the movement of promising ideas into clinical applications or other real-world applications and advance the field of melanoma-specific quality of life and survivorship. Study Design: Applications should clearly articulate and justify the chosen study design. Studies proposing retrospective analyses or prospective enrollment should clearly describe the architecture of the study (e.g., descriptive, correlational, field experimental, meta-analyses) and the study population(s). The study population(s) should be representative of the people who are anticipated to benefit from the research. If applicable, questionnaires should be described in sufficient detail to justify interpretation of potential results. Melanoma Consumer Collaboration: For the purposes of the SRA, a melanoma consumer is defined as a melanoma survivor, family member, and/or caregiver who can provide lived experience expertise to the research project team. Applicants to the SRA are required to establish a collaborative research approach with the melanoma consumer community to maximize the impact and translatability of the research for the benefit of the intended melanoma community(ies). The research team must include at least one melanoma consumer or a melanoma-community supporting organization who will be integral to the planning, execution, and implementation of the proposed research. The role of the melanoma consumer collaborator(s) should include providing objective input on the research question being addressed; the study design, execution, and evaluation; and the potential impact of the research outcomes on the health and well-being of melanoma survivors, their families, and/or their caregivers. The melanoma consumer collaborator(s) should be active participants and integrated into the research team; their participation should not be limited only to passive activities (e.g., attending seminars or quarterly team meetings). Additional information and resources for establishing a collaborative research approach with the melanoma consumer community is provided below.Other Important Considerations:Collaborative Research Approaches: Collaborative research approaches create partnerships between scientific researchers and, for the purposes of the SRA, melanoma consumers to create knowledge useable by both sets of stakeholders. Recognizing the strengths of each partner, scientific researchers and melanoma consumers collaborate and contribute equitably on all aspects of the project, which may include needs assessment, planning, research intervention design, implementation, evaluation, and dissemination. Collaborative research approaches feature shared responsibility and ownership for the research project to ensure non-tokenistic involvement of the melanoma consumers within the research team. Research results are jointly interpreted, disseminated, and fed back to affected communities and in some instances may be translated into interventions or policy.Collaborative relationships with the melanoma consumer community may be established through integrating melanoma consumers and/or melanoma-community supporting organizations into research teams as co-researchers, advisors, and/or consultants. Examples for implementing collaborative research approaches are listed below, but each research team may pursue other options as appropriate for the proposed research: The research team includes at least one melanoma consumer who will provide advice and consultation throughout the planning and implementation of the research project. The consumer(s) should be able to speak to the needs of the melanoma consumer community, not just speak to their own personal experiences. The research team establishes partnerships with at least one community-supporting organization that provides advice and consultation throughout the planning and implementation of the research project. Community-supporting organizations may include advocacy groups or other formal organizational stakeholders that can speak to the needs of the melanoma consumer community. The research team assembles a melanoma consumer community advisory board. The advisory board may include melanoma consumers, a coalition of community-supporting organizations, or any combination thereof that provides advice and consultation throughout the planning and implementation of the overall program and/or individual research projects.

The Central Indiana Community Foundation (CICF) is offering the Elevation Grant Program to support community-based efforts in Marion County, Indiana. This program aligns with CICF's mission to foster a thriving community by focusing on areas critical to well-being and equitable opportunity. The grant aims to empower residents and organizations to address systemic challenges through targeted interventions, ultimately leading to a more inclusive and resilient Central Indiana. The grant targets a diverse range of beneficiaries, including residents in specific neighborhoods, youth and young adults facing unique challenges, individuals currently interacting with the criminal legal system, and a priority population of Black/Latinx males aged 18-35 who are at high risk of violent victimization or perpetration. The impact goals are broad, encompassing increased resident safety, strengthened social networks, reduced crime, improved educational and employment outcomes for youth, enhanced social-emotional development, reduced recidivism, and comprehensive crisis response services for vulnerable populations. The Elevation Grant Program prioritizes five key areas: Thriving Neighborhoods, Empowered Youth / Young Adult, Restoration & Resilience, Justice-Involved Supports, and Intervention. Thriving Neighborhoods focuses on place-based efforts to promote safety and reduce crime, emphasizing resident engagement and community partnerships. Empowered Youth / Young Adult programs provide supportive services like employment, education, and mentoring to youth and young adults facing disengagement. Restoration & Resilience aims to offer social-emotional development, mental health support, and substance use reduction programs. Justice-Involved Supports focuses on services for individuals interacting with the criminal legal system to promote productive citizenship and reduce recidivism. Intervention programs implement integrated 24/7 crisis response services for the priority population, including housing, food, childcare, and mental health support. Expected outcomes and measurable results are integral to the grant program. For Thriving Neighborhoods, organizations must demonstrate increased resident safety and awareness through surveys, crime reporting, or statistics. Empowered Youth/Young Adult programs should show improved conditions for participants through measurable impacts of services and formal mentorship components. Justice-Involved Supports require demonstration of an individual's ability to gain skills, obtain work, secure housing, and prevent future interactions with the criminal legal system. The overall theory of change for CICF's Elevation Grant Program is to invest in strategic, community-led initiatives that address root causes of inequity and disengagement, thereby fostering a stronger, safer, and more equitable community for all residents of Marion County. The grant size ranges from $100,000 to $500,000 for an initial grant, with funding for the priority population ranging from $20,000 to $250,000. The grant duration is one year, with the grant period beginning October 1, 2024, and ending September 30, 2025. Eligibility criteria include being a 501(c)(3) public charity or having a fiscal sponsor, being located in and serving residents of Marion County, Indiana. Organizations may apply to multiple interest areas.

The Ion Bank Foundation is currently accepting applications for its grant program, designed to support organizations and initiatives that contribute to the betterment of communities it serves. The foundation's mission is aligned with fostering community well-being through strategic investments in various key areas. This program offers both designated and competitive grants, with competitive grants specifically targeting direct costs for starting or improving programs, as well as capital needs. The foundation emphasizes that indirect/overhead expenses are permitted, with specific documentation required for overhead exceeding 10% of the request. The grant program targets a broad range of beneficiaries within Hartford County, Litchfield County, and New Haven County in Connecticut, and Morris County in New Jersey. The primary impact goal is to address demonstrated community needs and advance community plans. The foundation seeks to achieve this by funding projects that show potential for leveraging additional or sustaining support, clearly explain their project plan, and provide a realistic budget. The Ion Bank Foundation's strategic priorities include affordable housing and rehabilitation, community services (encompassing healthcare, education, job training, social services, childcare, and credit/financial services), economic development, and the revitalization or stabilization of distressed or underserved areas. The foundation's theory of change posits that by investing in these key areas, it can contribute to a more stable, healthy, and prosperous community environment. Expected outcomes and measurable results include the successful implementation of evidence-based programs, improved community services, enhanced economic opportunities, and the revitalization of targeted areas. The foundation looks for strong proposals that summarize an organization's track record, adopt evidence-based models, and demonstrate a clear project plan. Preference is given to requests with broad, visible community involvement and collaborative ventures, indicating a focus on collective impact and sustainable change. Eligibility for the grant program extends to non-profit organizations recognized under Section 501(c)(3) of the Internal Revenue Code, municipal entities seeking grants for public purposes, and religious organizations undertaking nonsectarian projects aligned with the foundation's priorities. Applicants must be located in, or serve communities within, Ion Bank's defined assessment area for Community Reinvestment Act (CRA) purposes. Grants typically range from $1,000 to $10,000.

The Arts & Culture Capacity Building Grant Program, offered by the City of Dubuque, is designed to support initiatives that foster more sustainable and effective arts and culture organizations within the city. This program aligns with a mission to strengthen the operational capacity of local arts and culture entities, ensuring their long-term viability and ability to contribute to the community. Funding is available for fiscal year 2025, from July 1, 2024, through June 30, 2025, with a total of $35,000 allocated for grants ranging from $1,000 to $10,000, although eligible organizations can apply for up to $8,000. The primary beneficiaries of this grant program are arts and culture organizations that are nonprofit 501(c)(3) organizations, have at least two years of programming documentation and two Form 990s, and are officially located within the city limits of Dubuque. These organizations must serve residents of Dubuque and conduct programming within the city. The program aims to impact these organizations by enhancing their capacity in various key areas, ultimately leading to improved organizational health and effectiveness. The program prioritizes a range of capacity-building initiatives. These include strategic planning, creating development plans and/or fundraising strategies, improving donor experience, providing nonprofit 101 training for staff and board members, leadership development, project or program development, program management, volunteer management, and Diversity, Equity, Accessibility, and Inclusion (DEAI) training. These focus areas are intended to address common challenges faced by arts and culture organizations and equip them with the tools and knowledge needed to thrive. Expected outcomes include organizations with stronger strategic frameworks, enhanced fundraising capabilities, improved donor engagement, more skilled staff and board members, and more effectively managed projects and programs. Measurable results would involve the successful implementation of these capacity-building initiatives, which could be tracked through reports detailing new strategic plans, implemented fundraising strategies, attendance at training sessions, and improved operational metrics. The City of Dubuque's strategic priorities for this grant program appear to be rooted in a theory of change that by investing in the foundational and operational strength of its arts and culture sector, it will foster a more vibrant, resilient, and inclusive cultural landscape for its residents.

The City of Champaign's Community Matters youth program, founded in 2007, offers funding for the 2024-2025 program year. This initiative aligns with the city's mission to address critical areas such as safety, academic support, technology, recreation, career exploration, and employment among its youth. The program seeks to support public or private non-profit agencies that provide services meeting the needs of Pre-K through 18-year-old students residing within Champaign. The primary beneficiaries of this grant are youth from low-income families within the City of Champaign. The program's impact goal is to have a lasting positive effect on the community by fostering well-rounded development in its youth. While open to low-income youth from any Champaign neighborhood as space and funding allow, a key prioritization is given to programs serving youth from specific target areas: Beardsley Park, Bristol Park, Garden Hills, and Douglass Park, ensuring that resources are directed where they are most needed for community transformation. Proposals should focus on activities that can be carried out with Community Development Block Grant (CDBG) funds. These activities are broad and include the rehabilitation of residential and non-residential structures, building demolition, construction and rehabilitation of public facilities, and public services. However, activities related to the general conduct of government, political activities, and new housing construction are generally ineligible. This focus ensures that the funded programs directly contribute to community improvement and youth development. The expected outcomes include enhanced safety, improved academic performance, increased technological literacy, greater recreational opportunities, and better career exploration and employment prospects for the youth participants. While specific measurable results for the 2024-2025 allocation are dependent on the yet-to-be-announced CDBG annual allocation, the previous year's public service allocation of approximately $133,000 provides an indication of the funding scale. This funding, limited to 15% of the City of Champaign’s total CDBG award, underscores the strategic priority of public services within the broader community development framework, aiming for a significant impact despite funding constraints. The funding period runs from July 1, 2024, to June 30, 2025.

This grant provides financial support for Cuyahoga County-based artists to fund public projects, events, or specific needs related to their creative practices.

The Healthy Soils Program (HSP) Block Grant Pilot Program, facilitated by the California Department of Food and Agriculture (CDFA) through the Solano County Farm Bureau, is designed to incentivize the implementation of conservation management practices across California. This program aligns with a broader mission to improve soil health, sequester carbon, and reduce atmospheric greenhouse gases (GHGs) by providing financial support to growers and ranchers. The initiative is a component of the California Climate Investments (CCI), which has allocated $50 million towards these environmental objectives. The primary beneficiaries of this grant program are California farmers, ranchers, agricultural business entities, and California Native Americans. Nonprofit organizations operating agricultural operations are also eligible, provided grant recipients are at least 18 years old. The program specifically targets producers in Alameda, Contra Costa, Sacramento, Solano, and Yolo Counties, with a priority given to those qualifying as socially disadvantaged. The overarching impact goals are to foster statewide adoption of sustainable agricultural practices, leading to enhanced soil health, significant carbon sequestration, and a measurable reduction in atmospheric GHG emissions. The program's priorities and focuses revolve around implementing specific conservation management practices. These include mulching (compost), cover crops, reduced tillage, riparian, herbaceous, and woody plantings, windbreaks, filter strips, and whole orchard recycling. Projects must be located on agricultural operations within California, encompassing row crops, vineyards, field and tree crops, commercial nurseries, nursery stock production, greenhouse operations producing food crops or flowers, and grazing lands. Excluded activities include cannabis cultivation, the use of potted plants or non-soil growth media, and research and product development. Expected outcomes and measurable results include an increase in the number of agricultural operations implementing soil health-improving practices, a quantifiable reduction in GHG emissions, and a documented increase in carbon sequestration across the state. The grant term is three years, with a maximum award of $100,000 per agricultural operation. This grant structure aims to provide substantial, sustained support to enable the successful adoption and maintenance of these beneficial practices, contributing directly to California's climate goals and fostering more resilient agricultural systems.

The Project Grants initiative, offered by Working Assumptions, is a new program designed to support artists, writers, educators, social workers, therapists, and creatives in exploring the relationship between photography and family in expansive and inventive ways. Working Assumptions believes that photography can illuminate the complexities of family life and foster compassion, aligning with their mission to support projects that spur reflection and dialogue around family, care systems, and kinship. This program directly reflects the foundation's strategic priority to use photography as a medium for social commentary and understanding, operating under the theory of change that creative projects can significantly influence public perception and dialogue on critical societal structures like family. The primary beneficiaries of this grant are individual artists, collaborations, researchers, academics, journalists, educators, therapists, social workers, and creatives across disciplines who focus on photography and family. Applicants must have a prior track record of exploring family themes, be U.S. citizens or residents with a U.S. tax ID and bank account, and be at least 18 years old. The impact goals are to inspire audiences and participants to view family in new, meaningful ways through photography, fostering greater understanding and compassion for diverse family experiences. The program prioritizes projects that address underrepresented family arrangements, care work, memory, identity formation, and other related topics. While the grant offers unrestricted funding for creative freedom, it expects projects to be intended for public consumption, ranging from photography series and book projects to public art, mental health programs, long-form journalism, curriculum, performances, and digital or scholarly projects. This broad scope allows for diverse approaches to the central theme, ensuring a wide array of perspectives are brought to light. Expected outcomes include the creation and public dissemination of innovative photographic and interdisciplinary projects that provoke thought and dialogue. Measurable results will include the completion of 6 projects annually, each receiving $10,000 in funding over an 8-month grant period (September 15 to May 15). While the funding is unrestricted, the emphasis on public consumption implies that the success of these grants will also be measured by their reach and the degree to which they engage and inspire audiences to reflect on family dynamics and kinship.

The 2024-25 Physical and Digital Infrastructure Security Grant (DF) Program for Health Care Facilities, offered by the California Governor’s Office of Emergency Services (Cal OES), aims to enhance physical and digital security for healthcare facilities in California. This program aligns with the foundational mission of protecting vital health services and ensuring the safety of facilities that provide abortion-related and reproductive healthcare, which are often targets of violence and vandalism. The grant seeks to mitigate these threats, thereby supporting the continuity and accessibility of critical healthcare services across the state. The target beneficiaries of this grant are currently licensed community health centers, tribal health programs, non-profit hospitals not part of large health systems, and non-profit organizations whose membership includes such licensed facilities. All eligible applicants must be located in California and provide abortion-related services (or referrals) and reproductive healthcare services. The impact goal is to strengthen the security infrastructure of these facilities, creating safer environments for both patients and staff, and ensuring uninterrupted access to essential healthcare. The program's priorities and focuses include providing funding for physical facility enhancements, such as improved security measures for buildings, and digital security enhancements to protect against cyber threats and data breaches. The grant specifically targets facilities that may be vulnerable to violence and vandalism due to the nature of the services they provide. The funding aims to directly address these vulnerabilities, thereby safeguarding the operational capacity of these crucial healthcare providers. Expected outcomes and measurable results include a demonstrable improvement in the physical and digital security posture of funded facilities. This could involve a reduction in incidents of vandalism or violence, enhanced data protection, and increased patient and staff safety. The grant period is from September 1, 2024, through December 31, 2026, during which time facilities are expected to implement and integrate these security upgrades. Applicants can request up to $750,000 from the total available funding of $7,798,822. While specific "Foundation's strategic priorities and theory of change" are not explicitly detailed for Cal OES in the provided text, the underlying theory of change for this grant program appears to be that by providing targeted funding for security enhancements, the state can directly reduce risks to essential healthcare infrastructure. This proactive investment is expected to lead to greater resilience for healthcare facilities, particularly those offering sensitive services, thereby upholding public health and safety and ensuring that all Californians have access to necessary medical care without fear or disruption.

The Pfizer Sickle Cell Disease (SCD) Fellowship Grant is designed to bolster the number of fellowship programs focused on hematologists who specialize in the treatment of adults with sickle cell disease. This initiative is part of Pfizer Global Medical Grants' broader strategy to support healthcare community-led initiatives that enhance patient outcomes in critical areas of unmet medical need, aligning with Pfizer’s own medical and scientific strategies. The grant aims to enhance the quality of care for sickle cell patients by funding institutions that provide comprehensive training and research opportunities in the field. Specifically, the program supports both established and newly developed fellowship programs that include a robust curriculum in clinical practice, independent research, and education to deepen the scientific understanding of SCD. The fellowship is structured to foster an environment of expert mentorship and significant independent research opportunities. Research activities encouraged under this grant include observational studies and outcomes research that focus on the disease itself, screening tools, and their impact on patient health improvement. Grant funding is set at a maximum of $100,000 for a one-year fellowship, aiming to cover direct costs associated with the fellow’s training and research but explicitly excluding overhead or indirect costs. This financial support underlines Pfizer's commitment to advancing healthcare by investing directly in the development of professionals who are dedicated to improving patient outcomes in the field of sickle cell disease. Key to the grant’s operational framework is compliance with stringent regulatory requirements, including the U.S. Physician Payments Sunshine Act. This act mandates detailed reporting of all transfers of value to ensure transparency and maintain public trust in healthcare practices. The fellowship’s funding structure is designed to be transparent, with specific provisions to prevent any of the funds from benefiting Pfizer's business interests directly or indirectly. Overall, the Pfizer SCD Fellowship embodies a strategic effort to cultivate talent and advance knowledge in a critical area of healthcare, ensuring that the supported programs maintain high standards of integrity and contribute significantly to the field's body of knowledge and patient care practices.

The FY24 PCRP Implementation Science Award supports studies that are expected to bridge the gap between research, practice, and policy through establishment of a knowledge base of interventions, clinical practices/guidelines, tools, and policies that can be deployed to targeted populations at the appropriate time and point of need. For the purposes of this funding opportunity, an implementation science study accesses strategies used and develops tools to enhance the systematic uptake of evidence-based health interventions into clinical and/or community settings in order to improve patient outreach, patient outcomes, and/or the effectiveness of health care.Impact: Research supported by the Implementation Science Award is expected to have the potential for major, near-term impact that will accelerate the widespread adoption of evidence-based practices in prostate cancer care, prevention, and survivorship. Applications are expected to identify the prostate cancer patients or at-risk individuals who would ultimately benefit from the proposed research. Applications must also include a detailed research transition plan that articulates the pathway to moving the projects findings to the next phase for widespread clinical impact after successful completion of the award. Research transition plans are encouraged to consider future strategies targeting the patient, physician/provider, community, and/or healthcare system levels as applicable.Community Engagement: Applications are required to include members of the targeted population and/or community in the development and execution of the research project where appropriate. The research team must include one or more prostate cancer consumer advocate(s) or member(s) of the community, who will be integral throughout the planning and performance of the research project. Consumer advocates and/or community-based members should be involved in the development of the research question, project design, oversight, recruitment, and evaluation and dissemination of outcomes, as well as other significant aspects of the proposed project. Interactions with other team members should be well integrated and ongoing, not limited to attending seminars and semi-annual meetings; communication between the research team and the community should be frequent and bidirectional. The consumer advocates can be individuals who have been diagnosed with prostate cancer, a direct caregiver for someone who has been diagnosed with prostate cancer, or other representatives from the targeted community who are positioned to effect change. The consumer advocates and/or community-based members should have a high level of knowledge of current prostate cancer issues and the appropriate background in prostate cancer research and/or clinical care to contribute to the project or be otherwise positioned within the target community to effect changes in behavior based on projected outcomes. A list of implementation science resources and community or advocacy organizations is provided at the end of the Implementation Science Award Information section.Health Equity and Disproportionately Affected Populations: Regardless of the FY24 PCRP Overarching Challenge(s) being addressed, all research projects are strongly encouraged to consider health equity (e.g., access to evidence-based care) and/or have a focus on addressing the needs of disproportionately affected populations in the application.Research Scope: The Implementation Science Award mechanism is intended to fund studies including, but not limited to, the following: Small-scale clinical trials (up to phase 2) that contain clear reporting and implementation strategies to narrow the research-to-practice timeline and improve care for prostate cancer survivors, particularly within disproportionately affected populations Interventions that focus on behavioral or lifestyle changes at the patient, provider, community, and/or policy level Comparative effectiveness research establishing the benefits and harms of emerging or standard-of-care interventions and strategies to prevent, diagnose, treat, and monitor health conditions in real-world settings Development and evaluation of strategies to overcome barriers to health care access across the cancer care continuum Altering the adoption, adaptation, integration, scale-up, and sustainability of evidence-based interventions, tools, policies, and guidelines.Preliminary data to support the scientific rationale and feasibility of the research approaches are required. These preliminary data do not need to have been generated solely in prostate cancer. The inclusion of additional preliminary data to support the clinical relevance of the idea is strongly encouraged.Investigators proposing a clinical trial are highly encouraged to consider leveraging the PCRP Prostate Cancer Clinical Trials Consortium (https://pcctc.org) to facilitate the rapid initiation and completion of the trial.Correlative studies that are associated with ongoing clinical trials, and preclinical studies involving the use of animals do not meet the intent of the FY24 PCRP Implementation Science Award.Partnering Principal Investigator (PI) Option: The FY24 PCRP Implementation Science Award encourages applications that include meaningful and productive collaborations between two investigators. The PIs may have expertise in similar or disparate scientific and/or clinical disciplines, but each PI is expected to bring distinct contributions to the application. The Partnering PI Option is structured to accommodate two PIs. One PI will be identified as the Initiating PI and will be responsible for the majority of the administrative tasks associated with application submission. The other PI will be identified as a Partnering PI. Both PIs should contribute significantly to the development and execution of the proposed research project. If recommended for funding, each PI will be named on separate awards to the recipient organization(s). Each award will be subject to separate reporting, regulatory, and administrative requirements. For individual submission requirements for the Initiating and Partnering PIs, refer to Section II.D.2, Content and Form of the Application Submission.A congressionally mandated Metastatic Cancer Task Force was formed with the purpose of identifying ways to help accelerate clinical and translational research aimed at extending the lives of advanced state and recurrent patients. As a member of the Metastatic Cancer Task Force, the CDMRP encourages applicants to review the recommendations (https://health.mil/Reference-Center/Congressional-Testimonies/2018/05/03/Metastatic-Cancer-Research) and submit research ideas to address these recommendations provided they are within the limitations of this funding opportunity and fit within the FY24 PCRP prioritiesInnovative research involving nuclear medicine and related techniques to support early diagnosis, more effective treatment, and improved health outcomes of active duty Service Members and their Families is encouraged. Such research could improve diagnostic and targeted treatment capabilities through noninvasive techniques and may drive the development of precision imaging and advanced targeted therapies.Applications from investigators within the military services and applications involving multidisciplinary collaborations among academia, industry, the military services, the U.S. Department of Veterans Affairs (VA), and other federal government agencies are highly encouraged. These relationships can leverage knowledge, infrastructure, and access to unique clinical populations that the collaborators bring to the research effort, ultimately advancing research that is of significance to Service Members, Veterans, and/or their Families. If the proposed research relies on access to unique resources or databases, the application must describe the access at the time of submission and include a plan for maintaining access as needed throughout the proposed research.All projects should adhere to a core set of standards for rigorous study design and reporting to maximize the reproducibility and translational potential of clinical and preclinical research. The standards are described in SC Landis et al., 2012, A call for transparent reporting to optimize the predictive value of preclinical research, Nature 490:187-191 (https://www.nature.com/nature/journal/v490/n7419/full/nature11556.html). While these standards are written for preclinical studies, the basic principles of randomization, blinding, sample-size estimation, and data handling derive from well-established best practices in clinical studies.A Clinical Trial Option allows for studies proposing small-scale clinical trials with a focus on implementation science. A clinical trial is defined in the Code of Federal Regulations, Title 45, Part 46.102 (45 CFR 46.102) as a research study in which one or more human subjects are prospectively assigned to one or more interventions (which may include a placebo or another control) to evaluate the effects of the interventions on biomedical or behavioral health-related outcomes. Applications proposing a clinical trial are expected to provide detailed plans for initiating the clinical study within the first year, including U.S. Food and Drug Administration (FDA) Investigational New Drug/Investigational Device Exemption application submission plans, within 60 days of the award.Studies that do not seek to measure safety, effectiveness, and/or efficacy outcome(s) of an intervention are not considered clinical trials.For the purposes of this funding opportunity, research that meets the definition of a clinical trial is distinct from clinical research. Clinical research encompasses research with human data, human specimens, and/or interaction with human subjects. Clinical research is observational in nature and includes:(1) Research conducted with human subjects and/or material of human origin such as data, specimens, and cognitive phenomena for which an investigator (or co-investigator) does not seek to assess the safety, effectiveness, and/or efficacy outcomes of an intervention. Research meeting this definition may include but is not limited to: (a) mechanisms of human disease, (b) diagnostic or detection studies (e.g., biomarker or imaging), (c) health disparity studies, and (d) development of new technologies.(2) Epidemiologic and behavioral studies that do not seek to assess the safety, effectiveness, and/or efficacy outcomes of an intervention.(3) Outcomes research and health services research that do not fit under the definition of clinical trial.Excluded from the definition of clinical research are in vitro studies that utilize human data or specimens that cannot be linked to a living individual and meet the requirements for exemption under 46.104(d)(4) of the Common Rule.Implementation Sciences Resources: Potential applicants for this award are encouraged to seek collaborations and access to appropriate study populations through the following (or similar) resources: CDMRP: Search the CDMRP awards database at https://cdmrp.health.mil. The North Carolina Louisiana Prostate Cancer Project (PCaP): The PCaP was supported by the PCRP to conduct prostate cancer health disparity studies and developed a large biorepository of health disparity-related epidemiological data and biospecimens that may be requested for use by the research community. Information on PCaP investigators, data, and specimens is available at https://pcap.bioinf.unc.edu. National Cancer Institute Center to Reduce Cancer Health Disparities: Search for health disparity research and researchers at https://crchd.cancer.gov/index.html. National Institute on Minority Health and Health Disparities (NIMHD), National Institutes of Health (NIH), Community-Based Participatory Research (CBPR) Initiative: Contact the NIMHD at https://www.nimhd.nih.gov/programs/extramural/community-based-participatory.html for information on current CBPR programs and scientists and communities engaged in health disparity research. Cancer Prevention and Control Research Network (CPCRN): Contact the CPCRN at https://cpcrn.org/ for information on community participatory research to reduce cancer in disproportionately affected populations. Health Resources and Services Administration, Office of Minority Health: Search for health disparity programs and funded investigators at https://www.hrsa.gov/index.html. NIH Research Portfolio Online Reporting Tool (NIH RePORTER): Search for NIH awards at https://projectreporter.nih.gov/reporter.cfm. Defense Technical Information Center (DTIC): Search for Department of Defense (DOD) and other government-funded investigators through DTIC Technical Reports at https://discover.dtic.mil/. National Library of Medicine, NIH, PubMed: Search for investigators publishing studies on prostate cancer health disparities at https://www.ncbi.nlm.nih.gov/pubmed. U.S. Department of Education: Search for institutions that may have increased access to disproportionately affected populations at https://www2.ed.gov/about/offices/list/ocr/edlite-minorityinst.html. International Cancer Research Partnership: Search for investigators and studies relevant to health disparity that are supported by cancer research funders from several countries including the United States, European Union, United Kingdom, and Canada at https://www.icrpartnership.org. National Coalition for LGBT Health: For more information on programs focused on Lesbian, Gay, Bisexual, and Transgender (LGBT) research, policy, education, and training, search https://www.healthlgbt.org. National LGBT Cancer Network: To obtain more information, search https://www.cancer-network.org.In addition, the following is a list of potential community and/or advocacy organizations that applicants may find helpful to satisfy the requirement for community engagement within their proposed studies: the American Indian Health Care Association, National African American Outreach Program of the Patient Advocate Foundation, National Alliance for Hispanic Health, National Medical Association, National Rural Health Association, and Prostate Health Education Network, as well as international organizations such as the African-Caribbean Cancer Consortium, African Organization for Research and Training in Cancer, Europa Uomo, European Cancer Patient Coalition, Global Prostate Cancer Alliance, Malecare, Men of African Descent and Carcinoma of the Prostate Consortium, Prostate Cancer Transatlantic Consortium, Urban League, and The Prostate Net.The funding instrument for awards made under the program announcement will be grants (31 USC 6304).The anticipated direct costs budgeted for the entire period of performance for an FY24 PCRP Implementation Science Award should not exceed $2.0M. Refer to Section II.D.5, Funding Restrictions, for detailed funding information.Awards supported with FY24 funds will be made no later than September 30, 2025.The CDMRP expects to allot approximately $9.6M to fund approximately three PCRP Implementation Science Award applications. Funding of applications received is contingent upon the availability of federal funds for this program, the number of applications received, the quality and merit of the applications as evaluated by peer and programmatic review, and the requirements of the government. Funds to be obligated on any award resulting from this funding opportunity will be available for use for a limited time period based on the fiscal year of the funds. It is anticipated that awards made from this FY24 funding opportunity will be funded with FY24 funds, which will expire for use on September 30, 2030.

The U.S. Geological Survey (USGS) Great Lakes Science Center is offering a funding opportunity to a CESU Partner for research to determine the effects of incubation temperature on survival, growth, morphology, and gene expression of artificially reared cisco (Coregonus artedi) from the Great Lakes. This work is in support of ongoing efforts to develop a cisco hatchery strain that may be used to restore cisco to Lake Huron and other Great Lakes. Hatchery and resource managers are interested in understanding the impacts of the early rearing environment on gene expression and ultimately the adult phenotype in cisco. Working with agency partners will collect cisco gametes from northern Lake Huron and rear them at the Tunison Laboratory of Aquatic Science. Using these fish, the objectives are to (1) evaluate the effects of three incubation temperature treatments on cisco survival, growth, morphology, and gene expression, (2) identify physiological responses to stress across temperature treatments, and (3) identify genes that vary in expression across temperature treatments that appear to play key roles in cisco survival and morphology.

he DOE SC program in High Energy Physics (HEP) hereby announces its interest in receiving interdisciplinary applications for open scientific research on Quantum Information Science (QIS) Enabled Discovery (QuantISED) to further the HEP mission to understand how the universe works at its most fundamental level. Successful applications will help define an exploratory program where innovative solutions for scientific discovery are developed and deployed to advance HEP science drivers and contribute to QIS research and technology for public benefit.The QIS subprogram within HEP has been developed over the last few years with a series of workshops, followed by funding opportunities in 2018 and 2019, and is aligned with a broader SC initiative in QIS and coordinated with various national and interagency QIS programs, including the National QIS Research Centers. Cross-cutting the traditional frontiers and thrusts of the HEP program, the QIS subprogram exploits the interdisciplinary nature of QIS and associated partnerships for exploratory, early-stage research aimed at high impact discoveries aligned with HEP science goals, but also driving developments in foundational QIS and related scientific and technology research areas.Such research is intended to create public benefit within HEPs Congressionally-authorized mission space by increasing human understanding of the physical universe and driving relevant developments of advanced technologies that support that mission.

The PRP EIRA supports research opportunities for investigators in the early stages of their careers. The Early Investigator is considered the Principal Investigator (PI) of the application and must exhibit strong potential for, and commitment to, pursuing a career as an investigator at the forefront of PD research; however, the PI is not required to have previous PD research experience.

The Pfizer Fellowship Grant for Transthyretin Cardiac Amyloidosis is a competitive grant initiative aimed at advancing the professional development of healthcare professionals specializing in the diagnosis and management of ATTR cardiac amyloidosis. This grant is dedicated to enhancing academic and clinical understanding of the disease through research and education. Offered to U.S.-based academic institutions, the program supports fellowship roles for Cardiologists or Heart Failure Advanced Practice Providers, emphasizing a balance of clinical practice, research, and educational outreach. The grant ensures that the supported activities are independent of Pfizer’s commercial interests, focusing on fostering substantial advancements in the field of cardiac health.

This funding opportunity provides financial support for collaborative geologic mapping projects aimed at identifying and assessing critical mineral resources across the United States, benefiting researchers, state agencies, and organizations involved in geology and natural resource management.

The FY24 DMDRP CTRA mechanism supports advanced translational research that will accelerate the movement of promising ideas in DMD research into clinical applications. Translational research may be defined as an integration of basic science and clinical observations. However, applicants should not view translational research as a one-way continuum from bench to bedside. The research plan must involve a reciprocal flow of ideas and information between applied and clinical research. As such, applications must include preliminary and/or published data relevant to DMD to support the proposed research project.This mechanism is intended to support established projects that have moved beyond the realm of basic research and proof of concept studies and have the potential to result in a near-term impact in clinical research or the clinic. Research projects investigating therapies that will be efficacious across the life span, including infants, toddlers, and non-ambulatory individuals, are strongly encouraged. Pilot, proof-of-principle clinical trials, and correlative studies to better inform development of drugs, devices, and other interventions are allowed.Early-Career Partnering PI Option: The FY24 DMDRP encourages applications that include meaningful and productive collaborations between investigators. In an effort to promote enhanced research capacity within the DMD field, the FY24 CTRA includes an option for an Early-Career Partnering Principal Investigator (PI). The Partnering PI Option is structured to accommodate two PIs. One PI will be identified as the Initiating PI and will be responsible for the majority of the administrative tasks associated with application submission. The Early-Career PI will be identified as the Partnering PI. Both PIs should contribute significantly to the development and execution of the proposed research project. If recommended for funding, each PI will be named on separate awards to the recipient organization(s). Each award will be subject to separate reporting, regulatory, and administrative requirements. For individual submission requirements for the Initiating and Partnering PI, refer to Section II.D.2, Content and Form of the Application Submission.The FY24 DMDRP CTRA offers two funding levels (refer to Section II.D.5 Funding Restrictions). Only one funding level category may be chosen per application, and the choice of application category is at the discretion of the applicant. The following are generalized descriptions of the scope of the research appropriate for each funding level:Funding Level 1: Funding Level 1 is intended to support smaller, less complex preclinical and/or clinical research. Pilot clinical trials are allowed. The proposal/applications direct costs budgeted for the entire period of performance should not exceed $650,000.Funding Level 2: Funding Level 2 is intended to support larger, more complex preclinical and/or clinical research. Pilot clinical trials are allowed. The proposal/applications direct costs budgeted for the entire period of performance should not exceed $1.35M.Additionally, both funding levels will support an Early-Career Partnering PI Option at the same maximum direct costs and periods of performance, respectively.For the purposes of this funding opportunity, research that meets the definition of a clinical trial is distinct from clinical research. Both pilot clinical trials and clinical research are permitted under this mechanism.A clinical trial is defined in the Code of Federal Regulations, Title 45, Part 46.102 (45 CFR 46.102) as a research study in which one or more human subjects are prospectively assigned to one or more interventions (which may include a placebo or another control) to evaluate the effects of the interventions on biomedical or behavioral health-related outcomes.Studies that do not seek to measure safety, effectiveness, and/or efficacy outcome(s) of an intervention are not considered clinical trials.Clinical research encompasses research with human data, human specimens, and/or interaction with human subjects. Clinical research is observational in nature and includes:(1) Research conducted with human subjects and/or material of human origin such as data, specimens, and cognitive phenomena for which an investigator (or co-investigator) does not seek to assess the safety, effectiveness, and/or efficacy outcomes of an intervention. Research meeting this definition may include but is not limited to: (a) mechanisms of human disease, (b) diagnostic or detection studies (e.g., biomarker or imaging), (c) health disparity studies, and (d) development of new technologies.(2) Epidemiologic and behavioral studies that do not seek to assess the safety, effectiveness, and/or efficacy outcomes of an intervention.(3) Outcomes research and health services research that do not fit under the definition of clinical trial.Excluded from the definition of clinical research are in vitro studies that utilize human data or specimens that cannot be linked to a living individual and meet the requirements for exemption under 46.104(d)(4) of the Common Rule.All investigators applying to FY24 DMDRP funding opportunities and conducting clinical research are encouraged to consult the Strategies to Promote Diversity in Muscular Dystrophy Research Participation developed by the MDCC.

The U.S. Geological Survey Southwest Biological Science Center (SBSC) is offering a funding opportunity to a CESU partner for research to understand the effects of solar photovoltaic (PV) panels, vegetation treatments, and additional solar project management activities affect plant community composition at the Gemini Solar Project.