Grants for County governments - Federal

This program will constitute a national CBA Provider Network (CPN) to deliver CBA services to an interdisciplinary HIV prevention workforce (e.g., professional, technical, clinical, and managerial staff) within CDC-funded state and local health departments and CBOs. In the United States, an estimated 1.2 million people are living with HIV. In recent years, the number of people with HIV (PWH) has increased while deaths have declined. Of PWH, about 87% were aware of their HIV status. In 2021, among people with diagnosed HIV, an estimated 75% received HIV medical care and 66% were virally suppressed. Promising progress has been made in HIV prevention as the estimated annual new HIV infections were 12% lower in 2021 (32,100 infections) compared to 2017 (36,500 infections). This decline was largely driven by a substantial decrease (34%) in new infections among 13- to 24-year-olds, mostly among gay and bisexual males. However, HIV prevention efforts must go further, and progress must be faster, for gains to equitably reach all populations and end the HIV epidemic. The National HIV/AIDS Strategy (NHAS) for the United States focuses on four goals: preventing new HIV infections, improving HIV-related health outcomes of people with HIV, reducing HIV-related disparities and health inequities, and achieving integrated, coordinated efforts that address the HIV epidemic among all partners. Successful HIV programs must recognize the syndemics that affect the people and places disproportionately affected by HIV. A syndemic is population-level clustering of social and health problems. In the context of HIV, a syndemic is when HIV clusters with one or more other diseases or health conditions within a specific population, driven by the contextual, structural and social factors that increase the adverse effects on the health of people and communities. Syndemics may include HIV, STIs, TB, viral hepatitis, overdose, and substance use, and other existing and emerging conditions or factors that may be related to or impact HIV. The Ending the HIV Epidemic in the US (EHE) initiative focuses on scaling up four sciencebased strategies in communities most affected by HIV across the country. The strategies are to diagnose all people with HIV as early as possible; treat people with HIV rapidly and effectively to result in sustained viral suppression; prevent new HIV transmissions by using proven interventions, including condom distribution, pre-exposure prophylaxis (PrEP), postexposure prophylaxis (PEP), and syringe services programs (SSP); and respond quickly to potential HIV outbreaks to get vital prevention and treatment services to people who need them. Toward achieving national HIV prevention goals, the Centers for Disease Control and Prevention (CDC) funds state and local health departments and community-based organizations (CBOs) to plan, integrate, implement, evaluate, and sustain HIV prevention and surveillance programs, prioritizing people disproportionately affected by HIV including gay, bisexual, and other men who have sex with men, in particular Black, Latino, and American Indian/Alaska Native men, Black women, transgender women, youth aged 13-24, and people who inject drugs. Racism, HIV stigma, discrimination, homophobia, poverty, and barriers to health care continue to drive disparities in HIV prevention. Building individual competencies and technical expertise among staff, strengthening organizational capacities, and enabling supportive structural environments are critical strategies Page 5 of 81 in addressing operational challenges for more effective HIV prevention and surveillance programs. Reflecting CDC’s continued investment in improving the performance of the nation’s HIV workforce, this NOFO will support the provision of capacity building assistance (CBA) services, including training and technical assistance (TA).

The goal of the Activity is to improve the health, well-being, and protection of children and adolescents (and their families) living with, affected by, and vulnerable to HIV through high-impact service delivery and social service system strengthening to sustain an effective response for children, adolescents, and their families through locally led solutions in North West Province. The United States Agency for International Development (USAID) is seeking applications for acooperative agreement from qualified entities to implement the Children, Adolescents, andFamilies in the HIV Epidemic in North West Province Activity. Subject to funding availabilityand at the discretion of the Agency, USAID intends to provide up to $20 million in total USAIDfunding over a five (5) year period. Eligibility for this award is restricted to local entities (seeSection C.1 of this notice of funding opportunity (NOFO) for eligibility requirements of localentities). USAID encourages applications from potential new local partners. The Activity will beimplemented in the North West Province of South Africa.

This funding opportunity provides financial support for U.S. institutions and organizations to develop innovative methods for identifying and safely sealing undocumented orphaned oil and gas wells, thereby reducing methane emissions and environmental risks.

Under this Funding Opportunity Announcement (FOA), DOL will award grants through a competitive process to organizations providing pre-apprenticeship services that support education, occupational skills training, and employment services to opportunity youth, ages 16 to 24, who are performing meaningful work and service to their communities. The YouthBuild program model prepares participants for quality jobs in a variety of careers, in diverse industry sectors, particularly in infrastructure sectors, and includes wrap-around services such as mentoring, trauma-informed care, personal counseling, transportation supports, and employment preparation - all key strategies for addressing violence in communities. YouthBuild applicants must include construction skills training and may include occupational skills training in other in-demand industries. This expansion into additional in-demand industries is the Construction Plus component. Eligible applicants for these grants are public or private non-profit agencies or organizations, including consortia of such agencies or organizations. These organizations include rural, urban, or Native American/Tribal entities that have previously served opportunity youth in a YouthBuild or other similar program. DOL will fund approximately 75 projects across the country. Individual grants will range from $700,000 to $1.5 million and require a 25 percent match from applicants, using sources other than federal funding. This FOA features a matching waiver for Tribal entities and U.S. insular areas which allows these entities to not include a match commitment in their applications. The grant period of performance for this FOA is 40 months, including a four-month planning period and a twelve-month follow-up period.

"Fluctuating cognition can occur in many types of dementia and is a core clinical feature of Dementia with Lewy Bodies. Cognitive fluctuations can last from seconds to days, are unpredictable (e.g., do not just occur in the evenings, as with sun-downing), and are associated with poor daily functioning for the patient. A number of small studies have suggested that cognitive fluctuations in subjects with dementia may be related to epileptiform discharges and impaired oscillatory activity on EEG, but it is not clear that these are the only factors involved in patient populations that often experience dysautonomia, orthostasis, and sleep disturbances. The etiology of cognitive fluctuations may be multi-factorial and may vary in different dementia populations. Understanding the physiology related to cognitive fluctuations is a critical next step to the development of treatment approaches and improving quality of life for these patients. This initiate would encourage research that will better characterize the physiology responsible for cognitive fluctuations in ADRD populations. Given their variable appearance and time course, it is anticipated that wearable digital devices will be important for capturing fluctuations in a timely fashion, and applicants should consider incorporating those device(s) capable of acquiring the relevant data to support the hypothesized mechanism(s). Applicants may focus on assessing multiple mechanisms in a specific ADRD population, or may chose to compare mechanisms across multiple types of ADRDs. "

Grant Title: Artificial Intelligence and Machine Learning Applied to Nuclear Science and Technology - This grant aims to fund research that uses AI and machine learning to improve the efficiency and effectiveness of nuclear science experiments, particularly in optimizing accelerators, detectors, and data analysis.

This funding opportunity supports research on the ethical, legal, and social implications of human genetics and genomics, particularly focusing on diverse perspectives and community engagement.

This funding opportunity provides financial support for conservation projects that engage youth in hands-on work experiences and skills development related to public lands and natural resource management, with a focus on promoting equity and climate resilience.

This funding opportunity supports early-stage postdoctoral researchers in cancer research by providing resources for structured training and professional development to advance their scientific careers.

(Reissue PAR-21-056) The purpose of this Program Announcement (PAR) is to enable analytical validation of strong candidate biomarkers for neurological diseases and conditions. Specifically, the goal of this PAR is to enable the rigorous validation of analytical methods for biomarker measurements, including evaluation of the detection method, its performance characteristics, and the optimal conditions that will generate reproducibility and accuracy consistent with FDA guidelines. This PAR assumes that 1) a candidate biomarker has already been identified, 2) detection method technology has already been developed, and 3) the research and/or clinical need and potential context of use has been identified.

Gabon has vast natural resources in its maritime and terrestrial ecosystems that are being exploited through illegal, unreported, and unregulated (IUU) fishing; illegal logging; and poaching. According to a 2019 report by the Environmental Investigation Agency, illegal logging costs Gabon an estimated $1 billion per year, while WildAid reports IUU fishing results in $610 million in losses per year. Objective of the grant: Raise public awareness about the devastating effects of illegal fishing, logging and encourage the community of Gabon to act against these detrimental practices. The goals of the awareness campaign on illegal fishing and logging are as follows: Raise Public Awareness: The primary goal is to educate and inform the community of Libreville and Gabon in general about the detrimental effects of illegal fishing and logging. Increase public understanding of the environmental, economic, and social consequences associated with these activities. Behavior Change: Encourage individuals to take a stand against illegal fishing and logging by adopting sustainable practices. Motivate citizens to report illegal activities, support conservation efforts, and promote responsible fishing and logging practices. Community Engagement: Foster a sense of ownership and responsibility among the community members of Libreville, and Gabon. Encourage active participation in events, workshops, and seminars that promote environmental conservation and sustainable resource management. Advocacy and Policy Support: Generate public support for stronger regulations and enforcement measures against illegal fishing and logging. Advocate for policy changes that enhance the protection of marine resources and forests in Gabon. Partnerships and Collaborations: Establish partnerships and collaborations with local organizations, government bodies, press and influencers to create a united front against illegal activities. Leverage collective efforts to maximize the campaign's impact and sustainable outcomes. Long-Term Awareness and Behavior Shift: Create a lasting impact by instilling a sense of responsibility and understanding of the importance of preserving marine resources and forests. Lay the foundation for long-term behavior change and sustainable practices among individuals and communities.

This grant provides funding for researchers to study how HIV and substance use disorder affect brain cell function, with the goal of uncovering new treatment strategies for individuals facing these combined challenges.

This funding opportunity supports researchers in conducting multi-site clinical trials to investigate the effects of natural products, such as botanicals and dietary supplements, on health, requiring a comprehensive plan for trial management and data analysis.

The purpose of the NINDS Postdoctoral Mentored Career Development Award is to support the ability of outstanding, mentored postdoctoral researchers to develop a potentially impactful research project with a comprehensive career development plan that will enable them to launch an independent research program. Candidates are encouraged to apply for support from this NINDS K01 any time between the second through fourth year of cumulative mentored postdoctoral research experience, and may be supported by this NINDS K01 within the first 6 years of cumulative postdoctoral research experience. Because the completion of a strong, well-planned, thorough career development plan, in addition to development of an impactful research project, is a critical aspect of this K01, applications are strongly encouraged early in the postdoctoral eligibility window. By the end of the proposed K01 award period, the candidate should be poised to begin an independent research career with a well-developed, impactful research project and the expertise required to become a leader in the field.This Funding Opportunity Announcement (FOA) is designed specifically for applicants proposing to serve as the lead investigator of an independent clinical trial, a clinical trial feasibility study, or a separate ancillary study to an existing trial, as part of their research and career development.

This funding opportunity supports research and evaluation projects that aim to improve strategies for preventing and addressing domestic violence, sexual assault, and stalking, targeting a range of eligible applicants including local governments, nonprofits, and educational institutions.

This funding opportunity provides financial support to various government and nonprofit organizations to improve access to medical forensic examinations for sexual assault survivors through the development and expansion of specialized programs and services.

This Notice of Funding Opportunity (NOFO) aims to support research on interdisciplinary population approaches to increasing awareness of the relationship between alcohol and cancer risk, understanding and changing social norms related to alcohol consumption, developing and/or evaluating alcohol policy approaches, and the development, testing, and implementation of population-level interventions to reduce alcohol-related cancer risk. Applications that address multiple levels of consumption, such as moderate and heavy drinking, are of particular interest, as well as those focusing on alcohol use disorder (AUD) from the perspective of cancer prevention and control. Proposals addressing understudied areas are encouraged, as is attention to underrepresented minority (URM) populations experiencing cancer and alcohol-related disparities such as American Indian, Alaskan Native, and sexual and gender minority populations.

This funding opportunity provides financial support to organizations that offer mentoring services to at-risk youth across multiple states, helping them improve their academic performance and avoid negative behaviors.

This funding opportunity supports researchers conducting multisite clinical trials and observational studies focused on women, children, pregnant and lactating individuals, and persons with disabilities, utilizing NICHD's established network infrastructure.

This funding opportunity supports doctoral candidates conducting research on maternal and child health using a large dataset to explore the impact of early environmental exposures on child health outcomes.