Grants for County governments - Federal

Reissue of RFA-NS-18-020: Understanding the dynamic activity of brain circuits is central to the NIH BRAIN Initiative. This FOA seeks applications for proof-of-concept testing and development of new technologies and novel approaches for recording and modulation (including various modalities for stimulation/activation, inhibition and manipulation) of cells (i.e., neuronal and non-neuronal) and networks to enable transformative understanding of dynamic signaling in the central nervous system (CNS). This FOA seeks exceptionally creative approaches to address major challenges associated with recording and modulating CNS activity, at or near cellular resolution, at multiple spatial and/or temporal scales, in any region and throughout the entire depth of the brain. It is expected that the proposed research may be high-risk, but if successful, could profoundly change the course of neuroscience research. Proposed technologies should be compatible with experiments in behaving animals, validated under in vivo experimental conditions, and capable of reducing major barriers to conducting neurobiological experiments and making new discoveries about the CNS. Technologies may engage diverse types of signaling beyond neuronal electrical activity such as optical, magnetic, acoustic and/or genetic recording/manipulation. Applications that seek to integrate multiple approaches are encouraged. If suitable, applications are expected to integrate appropriate domains of expertise, including biological, chemical and physical sciences, engineering, computational modeling and statistical analysis.

This funding opportunity supports collaborative research projects led by independent investigators to advance the understanding and treatment of infectious and immune-mediated diseases.

Rapid advances in genotyping and next generation sequencing technologies have led to the identification of genetic variants that are associated with a wide variety of congenital defects including structural birth defects (SBDs), intellectual developmental disabilities (IDDs) and inborn errors of metabolism (IEMs). Large quantities of genomic data collected from pediatric birth defects cohorts are available to the research community through several databases such as the Database of Genotypes and Phenotypes (dbGaP), the Gabriella Miller Kids First Data Resource Portal, the European Genome-Phenome Archive and Clinical Genome Resource (ClinGen). The purpose of this initiative is to promote the screening, functional validation and characterization of birth defects-associated genetic variants identified through public facing databases and individual efforts using in-silico tools, appropriate animal models, in vitro systems or multi-pronged approaches. This initiative addresses a challenging gap between identifying sequence variations of potential interest and recognizing which of those variations have functional effects on the phenotype of interest.

This funding opportunity supports researchers in conducting observational studies or validating biomarkers related to dental, oral, and craniofacial diseases, aiming to improve prevention, diagnosis, and treatment through prospective data collection and analysis.

The "U.S. Embassy Oslo Public Diplomacy Section (PDS) Annual Program Statement" grant aims to fund projects by eligible organizations and individuals that promote U.S.-Norway relations, with a focus on areas such as global security, Arctic issues, climate change, media influence, diversity, cultural heritage, shared values, U.S. higher education, and cross-border collaborations.

This grant provides funding to various government entities, educational institutions, and nonprofit organizations in New Mexico to manage and control invasive plant species on public lands, protecting native ecosystems and promoting community engagement.

This funding opportunity provides financial support to organizations working to strengthen export controls and compliance measures against the Chinese Communist Party's efforts to acquire advanced technologies for military and economic purposes.

This funding opportunity provides financial support to organizations working to review wrongful convictions and improve the integrity of the criminal justice system, particularly in underserved rural areas.

CDC announces availability of fiscal year 2024 funding for a cooperative agreement for Cycle 5 of the STD Surveillance Network (SSuN). Continuing resurgence of sexually transmitted infections (STIs), along with the imperative to implement syndemic approaches to disease surveillance addressing related epidemics such as Human Immunodeficiency Virus (HIV) and Mpox (Orthopox virus previously referred to as monkeypox) inform this competitive Notice of Funding Opportunity (NOFO) which will support integrated sentinel and enhanced surveillance at the local, state, and national level. Emergent issues of concern such as Mpox and antimicrobial resistant STIs add urgency to the maintenance of robust syndemic surveillance at the community level and in sexual health clinical settings. The purpose of this NOFO is to support sentinel and enhanced surveillance for STDs providing complete demographics, behavioral risk, clinical and preventive services data missing in routine reporting. Sentinel clinic surveillance, enhanced investigations of reported cases, and special projects funded by this NOFO will provide epidemiologic and preventive services information filling gaps in knowledge regarding STI prevention priorities. These data improve the ability of public health agencies to address STI/HIV health equity outcomes and syndemic interactions in populations with shared risks.This NOFO supports two core strategies for (A) sentinel surveillance in sexual health clinical facilities, and (B) enhanced case-based surveillance in community settings. Both core strategies integrate a syndemic approach to monitoring STIs, HIV, behavioral data, and on preventive services accessed by all persons presenting for care in sexual health settings, and persons diagnosed and reported with selected STIs from all provider settings in defined geographic areas. The goal of this NOFO is to monitor and report trends in patient characteristics, screening, and diagnoses to identify opportunities and gaps across the STI/HIV prevention continuum. Protocols are designed to address critical information gaps in routine national case reporting and incorporate local flexibility to respond to emergent health issues by supporting a network of geographically diverse health departments and an expanded network of clinical partners. These efforts complement existing state, local and national surveillance strategies and enhance the capacity of health departments to collect high-quality, timely data to inform disease prevention and control activities.

This funding opportunity provides financial support for research consortia focused on improving the diagnosis and treatment of rare diseases through collaborative, patient-centered clinical studies involving multiple institutions and patient advocacy groups.

The "Enhancing NIDCD's Extramural Workforce Diversity through Research Experiences" grant aims to fund educational activities that inspire individuals from diverse and underrepresented backgrounds to pursue careers or further studies in biomedical and behavioral sciences research.

This funding opportunity supports innovative research projects that aim to improve health outcomes and promote health equity in the U.S. by addressing social determinants of health and enhancing healthcare delivery systems.

This funding opportunity supports researchers in analyzing existing data from a major study on adolescent brain development and health to uncover new insights and address health disparities among youth.

This funding opportunity supports the development of innovative tools and methodologies to study the human virome, inviting a diverse range of organizations to enhance our understanding of how viruses impact human health and disease.

The "Neuropathological Interactions Between COVID-19 and ADRD" grant aims to fund research that investigates how COVID-19 affects the brain and cognitive outcomes in models with Alzheimer's Disease and related dementias (AD/ADRD), how it accelerates these conditions in early stages, and how it potentially increases the risk for future AD/ADRD.

This grant provides funding to state, local, and tribal governments, nonprofits, and educational institutions in the Southern U.S. to implement wildfire hazard mitigation projects that enhance community resilience and reduce fire risks.

This program is authorized by 34 U.S.C. 12421. The Training and Services to End Abuse in Later Life Program (Abuse in Later Life Program) (Assistance Listing # 16.528) supports a comprehensive approach to addressing abuse in later life, including domestic violence, dating violence, sexual assault, stalking, neglect, abandonment, economic abuse, or willful harm committed against victims who are 50 years of age or older.

The US Army Corps of Engineers, Portland District (USACE) intends to enter into a cooperative agreement with a non-Federal public entity or nonprofit organization for land stewardship and restoration services on USACE land at the Bonneville Lock and Dam in Skamania County, WA and Multnomah County, OR. This cooperative agreement will assist Portland District in fulfilling environmental stewardship responsibilities consisting of restoration and management of native and historic landscapes and wildlife habitat while providing education and training opportunities to the recipients participants in the local communities around Bonneville Lock and Dam. These education and training opportunities exist through the need for natural resource and maintenance services on public lands within Bonneville Lock and Dams jurisdiction. The goals and objectives of this cooperative agreement are for the implementation of best natural resources management practices with regards to environmental stewardship, high and low density recreation areas, and operations/facilities maintenance. Environmental and maintenance training opportunities include but are not limited to: Vegetation Management Vegetation PlantingPark and Trail MaintenanceLitter RemovalTrail Construction and Maintenance This cooperative agreement will be awarded pursuant to 33 USC 2339 Conservation and Recreation Management. The recipient for this cooperative agreement must be a qualified non-Federal public entity or nonprofit organization that serves low security inmates and/or individuals executing community service sentences within the Skamania County, WA, Clark County, WA, Hood River, OR and/or Multnomah County, OR correctional system, and has experience in land stewardship and restoration using small work crews supervised by experienced leaders so that ecological concepts can be accurately conveyed to work crew and leaders.

This grant provides funding to various organizations, including government agencies and nonprofits, to help farmers in the Western Lake Erie Basin adopt better nutrient management practices that reduce harmful agricultural runoff and improve water quality.

The Food and Drug Administration's (FDA), Center for Drug Evaluation and Research (CDER), Office of New Drugs (OND), is announcing this Funding Opportunity Announcement (FOA) for a Cooperative Agreement. The proposed work directly supports the U.S. FDAs stated goal of protecting public health from unacceptable risks from nitrosamine impurities in human drugs. Although significant experimental and policy/regulatory initiatives have been undertaken in this area, there remains a need for further research into and development and refinement of translational and implementable practices that will protect the public against nitrosamine risks while ensuring continued safe access to critical therapeutic drugs. The aim is to improve the safety of human drugs with potential nitrosamine impurity liabilities. In addition to the work outlined above, the award recipient will assess how best to ensure that this research and practices development continues among industry members, non-profits, and/or academic institutions once the FDA funding for this cooperative agreement ends.