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This solicitation describes an ambitious program to fund international, interdisciplinary collaborative research centers that will apply best practices of broadening participation and community engagement to develop use-inspired bioeconomy research to address one or more global challenges identified by the scientific community. Here, the "used-inspired" nature of the research refers to project outcomes leading to foreseeable benefits to society. This program will prioritize research collaborations that foster team science and community-engaged research, use knowledge-to-action frameworkswhose rationale, conceptualization, and research directions are driven by the potential use of the results as illustrated by Pasteurs Quadrant (see Stokes, Donald E. (1997), "Pasteur;apos;s Quadrant - Basic Science and Technological Innovation," Brooking Institution Press, p.196. ISBN 9780815781776).Proposals should also indicate how research will be co-generated with communities and stakeholders identified in the proposal. The proposed research should maximize the benefits of international, interdisciplinary collaborations, and describe the roles and responsibilities of each national team in achieving the goals of the proposed Global Center. Global Centers projects involving partnership between the U.S. and two or more partner countries are strongly encouraged. Global challenges must be addressed through international collaboration and researchers are encouraged to develop international teams to address research questions that can only be addressed through multilateral efforts. The topic for the 2024 competition of the Global Centers program is Addressing Global Challenges through the Bioeconomy and may include research from any combination of research disciplines supported by NSF. The Bioeconomy is the share of the economy based on products, services, and processes derived from living systems.Research investments to advance the bioeconomy serve to accelerate scientificdiscovery and to enable the harnessing, engineering, and rational modulation ofbiological systemsto create goods and services that contribute to the agriculture,health, security, manufacturing, energy, and environmental sectors of the global economy; or that provide access to unique systems that help us understand the processes and issues that we can use biotechnology to solve. Bioeconomy is built on the foundation of biotechnology and biomanufacturing, and in addition to biological science and engineering includes contributions from fields such as chemistry, materials science, geosciences, mathematics, data sciences, humanities, and the social sciences. The world is facing many serious challenges, including, but not limited to, adapting to or mitigating the effect of climate change, developing clean energy approaches, identifying and advancing sustainable food systems, addressing water insecurity, exploring solutions to emerging infectious diseases, creating resource efficiency, sustaining biodiversity, addressing inequalities in access to biotechnologies, and developing a circular bioeconomy. For example, bio-based materials offer heightened biodegradability and biosafety as compared to reusable plastic materials that shed microplastics during use and washing and affect water security and human health. This Global Centers solicitation in Bioeconomy offers a unique opportunity for interdisciplinary teams of scientists, educators, and practitioners to use knowledge of the bioeconomy to co-develop and execute a research plan for an international center that will address a global challenge facing humanity. The Global Centers program is meant to support multidisciplinary research that can only be achieved through international partnerships uniting complementary areas of expertise, and/or facilitating access to unique expertise or resources of the participating countries. The proposal should explain how the center will maximize the benefits of international collaborations and describe the unique contributions and the roles and responsibilities of each national team in achieving the goals of the proposed Global Center. Successful proposals will describe how the center will tackle a global challenge that can only be addressed through the diversity of knowledge, skills, and resources united in this center. Addressing global challenges requires international engagement and must go beyond production of data to demonstrate how co-generation and co-production of research with stakeholder groups can maximize the chances of research outcomes being taken up by target groups and applied to address the global challenge. Because change requires human involvement, this process, described as the Knowledge to Action framework explicitly recognizes the need to involve appropriate scientific experts and practitioners who study and work with humans in implementing the human action aspect of the framework. Examples of human action include (but are not limited to) studies in human and societal behavior, in policy, economics, psychology, anthropology, or education. Proposals are expected to describe a center that fully integrates human action elements with the knowledge generation portions of the center to produce a holistic, multi-disciplinary center that is greater than the sum of its parts. The center should offer a plan of research in which disciplines are integrated and complement and support each other to produce world class research, train the next generation of workforce, and use best practices to ensure that participant communities and stakeholder groups are involved in all stages of the research process so that outcomes are aligned with their needs and readily adoptable. Within the general theme of Bioeconomy, proposals submitted in the framework of this call must be centered on either or both of the two subtopics: Subtopic 1:Leveraging Biodiversity Across the Tree of Life to Power the Bioeconomy; and Subtopic 2: Biofoundries, using the Design-Build-Test-Learn process in biology. All proposals must integrate both of the two crosscutting themes into the proposed work: Crosscutting Theme A: Public engagement and co-generation of research activities to strengthen the global science and technology enterprise; andCrosscutting Theme B: Workforce Development and Education. See Section II, Program Description for details.

With this solicitation, NIJ seeks to support two (2) American Association for the Advancement of Science (AAAS) Science Technology Policy Fellowships (STPF) Fellows at NIJ. The AAAS STPF Fellow, as mutually agreed, will be assigned responsibilities across NIJs science offices depending on the interests of the science offices and the interests of the Fellows. Regardless of placement, the Fellows will have the opportunity to work across offices. The Fellows will have opportunities to engage in a range of science (including social and behavioral science), technology, engineering, and mathematics research development and evaluation projects.

The U.S. Department of State, Bureau of Democracy, Human Rights, and Labor (DRL) announces an open competition for organizations interested in submitting applications for projects that promote economic competitiveness through well-paying, quality jobs and dismantle systemic gender barriers that limit Haitians and Dominicans of Haitian descent women abilities to fully participate in the economy in the Dominican Republic.

Addendum # 24 The goal of the Malaria Elimination Activity is to advance Senegal toward its goal of malaria elimination by 2030. In the first year, the Malaria Elimination Activity will target the country's northern zone, with the regions of Matam, St-Louis and Louga, which have malaria annual incidence levels below the elimination threshold (below 5 per thousand). The anticipated mechanism is one fixed amount renewal award for specific programmatic activities and milestones.Addendum # 25 The purpose of the Strengthening Maternal, Newborn, and Child Health Care Activity is to reinforce the quality of the health care provided in health facilities in the three regions 9( Matam, Saint Louis and Louga), including supporting the functionality of obstetrical surgical units (blocs in French) and neonatal care services and improving the quality of family planning, maternal and child health (MCH), and nutrition services available in health facilities. Addendum #26 The purpose of the Community Health Social Behavior Change Activity is to improve the utilization of quality community health services in three regions (Saint Louis, Matam and Louga), increase preventive and care-seeking behaviors for maternal, newborn, and child health, family planning, nutrition, and zoonotic diseases, and improve leadership, management, and governance of community health.

The CTRA supports studies that will move promising, well-founded preclinical and/or clinical research findings closer to clinical application, including diagnosis, prognosis, or treatment of TSC. Projects supported by this award mechanism may include, but are not limited to: Studies moving from preclinical to clinical research and/or the reverse; or analyzing human anatomical substances and/or data associated with completed clinical trials to understand the mechanism of action, or to improve diagnosis, prognosis, or treatment. Studies advancing clinical trial readiness through development of biomarkers, clinical endpoints, and validation of pharmacokinetics/pharmacodynamics. Pilot clinical trials, where limited clinical testing (e.g., small sample size) of a novel intervention to produce information on diagnostic or therapeutic effectiveness, safety, tolerability, or mechanisms of action. These studies should be aimed at obtaining preliminary data leading to the development of interventions with the potential to improve TSC outcomes. New Studies improving clinical care of TSC encompassing the analysis of existing real-world clinical practice data to develop/improve guidelines for better outcomes in defined areas relevant to the FY24 TSCRP focus areas, include but are not limited to epilepsy surgery, tumor resection, reproductive health, perinatal surveillance and care, etc.Preclinical studies may be appropriate but must include a clinical component. Projects that are strictly animal research will not be considered for CTRA funding and should consider other FY24 TSCRP funding opportunities.

PLEASE NOTE: Amendment 2 extends the application closing date to 7/1/2024. Please read Amendments 1 and 2 (found in the Related Documents tab) for updates to the Funding Opportunity Announcement. The purpose of the DOL Building Pathways to Infrastructure Jobs Grant Program is to fund public-private partnerships to develop, strengthen, and scale promising and evidence-based training models in H-1B industries and occupations critical to meeting the goals of the Bipartisan Infrastructure Law (BIL) and to maximize the impact of these investments. The United States (U.S.) will need a proficient workforce to fill the good-paying jobs created by this historic investment, and this grant program will train job seekers in advanced manufacturing; information technology; and professional, scientific, and technical services occupations that support renewable energy, transportation, and broadband infrastructure sectors. The DOL Building Pathways to Infrastructure Jobs Grant Program represents a down payment for the future skilled workforce needs that are being developed through the BIL investments by investing in the development and expansion of the workforce partnerships that will be needed to build equitable pathways to good infrastructure jobs.The Infrastructure Investment and Jobs Grant Program serves dual purposes by implementing and scaling worker-centered sector strategies to support the workforce necessary for successful implementation of the BIL. Applicants must choose one of the following tracks for this grant program: 1) Development Track: Developing and Implementing Local/Regional Worker-Centered Sector Strategy Programs; or 2) Scaling Track: Scaling Effective Worker-Centered Sector Strategy Programs. The goal of the Development Track is to use promising training models to invest in and establish local/regional partnerships that will implement sector-based training programs across one or multiple infrastructure-related sectors. This track will support equitable participation and growth of worker-centered sector-based training programs, particularly those serving rural and smaller communities and historically marginalized, underrepresented, and underserved populations. The goal of the Scaling Track is to scale an existing training model to the statewide or national level, that has shown demonstrated success in one infrastructure-related sector. This track will invest in statewide and national partnerships that will set the stage to enable support and growth in evidence-based worker-centered sector strategies.Both tracks require public-private partnerships to develop workforce training programs which incorporate the following core principles into their grant project design to ensure equitable access to quality jobs: 1) strategies for ensuring diversity, equity, inclusion, and accessibility; 2) career pathways that lead to middle- to high-skilled employment; and 3) worker-centered sector strategies. To embed strong worker voice into these grant projects, applicants should engage workers during the initial grant proposal development phase to ensure that worker needs and priorities and job quality are incorporated into the project design.Questions regarding this Funding Opportunity Announcement (FOA) may be emailed to IN_FOA-ETA-23-31@dol.gov. We encourage prospective applicants and interested parties to use the Grants.gov subscription option to register for future updates provided for this particular FOA.

This funding opportunity is designed to support the National Children’s Alliance in strengthening local Children’s Advocacy Centers across the country to improve responses to child abuse through enhanced services and resources.

This funding opportunity provides financial support for projects that protect and conserve rhinoceroses and tigers in Asia, focusing on habitat preservation, anti-poaching efforts, and community engagement.

The USGS is offering a funding opportunity to a CESU partner for research in evaluating the efficacy of Incompatible Insect Technique (IIT) as a mosquito population suppression control strategy designed to disrupt the avian malaria disease cycle. The CESU partner will develop statistical models that incorporate capture rates of Southern house mosquitoes (Culex quinquefasciatus) and the prevalence of Plasmodium relictum in mosquito samples to characterize the efficacy of the IIT project and disease pressure on Hawaiian forest birds in critical forest bird habitat. Another component of this research will be to develop a high-throughput, next-generation sequencing technique to quantify the prevalence of avian malaria and test whether that approach is comparable to quantitative PCR-based avian malaria assays.

This is a Request for Information (RFI) only. This RFI is not accepting applications for financial assistance. The purpose of this RFI is solely to solicit input for ARPA-E consideration to inform the possible formulation of future programs. The purpose of this Request for Information (RFI) is to solicit input for a potential ARPA-E program focused on leveraging material, process, equipment, and cross-supply chain manufacturing innovations to catalyze domestic production of cathode active materials (CAMs) and their precursors (pCAMs). Most commercial lithium-ion batteries employ graphite anodes and layered transition metal oxide cathodes. CAMs can account for approximately 50% of total battery cost, while CAM chemistry determines overall battery performance and safety.5 To date, commercial cell-level energy densities exceeding 280 watt-hour per kilogram (Wh/kg) are achievable in batteries where NMC is used as the CAM in combination with a graphite anode.6 Recent optimization efforts have focused on innovations in chemistry to decrease cobalt content and increase nickel content thus simultaneously increasing energy density and reducing cost. Moreover, significant government and private sector research funding has been allocated to develop alternative lithium-based battery chemistries. Thus far, LFP is the most commercially successful nickel-free and cobalt-free cathode to be developed with notable attributes in cost, safety, and cycle life. Recent gains in market share suggest that LFP batteries may become the dominant chemistry for compact, economy EVs, while NMC is likely to continue to be the preferred cathode chemistry for vehicles where torque response and range are priorities. To view the RFI in its entirety, please visit https://arpa-e-foa.energy.gov.

The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative proposals to identify and optimize novel molecules that exhibit inhibitory effects on Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-CRISPR associated proteins (CRISPR-Cas) gene editing processes. The Broad-Spectrum Antagonists for Editors (B-SAFE) program is explicitly seeking transformative approaches enabling the discovery or design of novel inhibitors of gene editing technologies with enhanced activity, utility, and breadth of coverage. Novel inhibitor activity will be assessed in vitro over the course of the program and a subset of top performing molecules will be selected for scale-up at quantities sufficient for testing and evaluation by Department of Defense (DoD) stakeholders. In concert, DARPA is interested in exploring methods to rapidly discover inhibitor molecules for novel gene editing technologies beyond CRISPR-Cas systems to keep pace with the rapidly advancing field and promote the safe, controlled use of these technologies. Research that generates incremental improvements to the existing state-of-the-art are specifically excluded.

This funding opportunity provides financial support for innovative research projects aimed at improving safety in the U.S. railroad system, targeting researchers, universities, inventors, and private companies exploring new safety concepts.

1. PurposeThe Healthy Homes Production Program (HHP) is part of HUDs overall Healthy Homes Initiative launched in 1999. The program takes a comprehensive approach to addressing multiple childhood diseases and injuries in the home by focusing on housing-related hazards in a coordinated fashion, rather than addressing a single hazard at a time. The program builds upon HUDs successful Lead Hazard Control programs to expand the Departments efforts to address a variety of high-priority environmental health and safety hazards. Applicants receiving a Healthy Homes Production Award will be expected to accomplish the following objectives:Maximize both the number of vulnerable residents protected from housing-related environmental health and safety hazards and the number of housing units where these hazards are controlled;Identify and remediate housing-related health and safety hazards in privately owned, low-income rental and/or owner-occupied housing, especially in units and/or buildings where families with children, older adults 62 years and older, or families with persons with disabilities reside;Promote cost-effective and efficient healthy home methods and approaches that can be replicated and sustained;Support public education and outreach that furthers the goal of protecting children and other vulnerable populations from housing-related health and safety hazards;Build local capacity to operate sustainable programs that will prevent and control housing-related environmental health and safety hazards in low- and very low-income residences, and develop a professional workforce that is trained in healthy homes assessment and principles;Promote integration of this grant program with housing rehabilitation, property maintenance, weatherization, healthy homes initiatives, local lead-based paint hazard control programs, health and safety programs, and energy efficiency improvement activities and programs;Build and enhance partner resources to develop the most cost-effective methods for identifying and controlling key housing-related environmental health and safety hazards;Promote collaboration, data sharing, and targeting between health and housing departments;Ensure to the greatest extent feasible that job training, employment, contracting, and other economic opportunities generated by this grant will be directed to low- and very-low-income persons, particularly those who are recipients of government assistance for housing, and to businesses that provide economic opportunities to low- and very low-income persons in the area in which the project is located. For more information, see 24 CFR 135 (Section 3);Further environmental justice, the fair treatment, and meaningful involvement of all people within the target communities regardless of race, color, national origin, disability, religion, sex (including sexual orientation and gender identify), familial status or income regarding the development, implementation, and enforcement of environmental laws, regulations, and policies; k. Comply with Section 504 of the Rehabilitation Act of 1973 (Section 504) and its implementing regulations at 24 CFR part 8, as well as Titles II and III of the Americans with Disabilities Act when applicable. Each of these prohibits discrimination based on disability. In addition to these requirements, recipients have an obligation to comply with the Fair Housing Act, including the obligation to affirmatively further fair housing, and Title VI of the Civil Rights Act of 1964. Note that besides being an objective of this NOFO, the obligation to affirmatively further fair housing is also a civil right related statutory and program requirement.

This funding opportunity is designed to support Kyrgyz nonprofit organizations and educational institutions in fostering entrepreneurship and strengthening commercial ties with U.S. businesses to promote economic development in the Kyrgyz Republic.

The purpose of the Tribal Colleges Extension Program: Special Emphasis (TCEP-SE) is to support pilot projects in Extension at the 1994 Land-Grant institutions. A pilot project allows Extension offices to be responsive to community needs through projects that address youth, agriculture, economic development, or other issues important to stakeholders. The TCEP-SE is intended to be a component of the applicant 1994 institutions land-grant roadmap or strategic planning process and can be used to supplement their existing Tribal Colleges Extension Program (TCEP) capacity project by extending the reach of innovations in research and technology and enhancing informal, local educational programming.

NIEHS invites applications for cooperative agreements to support the development of model programs for the training and education of workers engaged in activities related to hazardous materials and waste generation, removal, containment, transportation and emergency response. This funding opportunity announcement aims to prevent work-related harm through safety and health training. The training programs will transmit skills and knowledge to workers in how best to protect themselves and their communities from exposure to hazardous materials encountered during hazardous waste operations, hazardous materials transportation, environmental restoration of contaminated facilities or chemical emergency response. A variety of sites, such as those involved with chemical waste cleanup and remedial action and transportation-related chemical emergency response, may pose severe health and safety concerns to workers and the surrounding communities. These sites contain many hazardous substances, sometimes unknown, and often a site is uncontrolled. A major goal of the Worker Training Program (WTP) is to support institutional competency-building for the development and delivery of model training and education programs.

As directed by Congress, SSP makes federal funds available to enable non-federal entities to off-set allowable costs incurred for services associated with noncitizen migrants recently encountered and released by DHS. As stated in the FY 2024 appropriation, the primary purpose of SSP is to reliev[e] overcrowding in short-term holding facilities of [CBP]. Recipients of SSP may also seek grant funds for renovations or costs associated with modifications to existing facilities in support of individuals who have recently been released from the custody of CBP. Refer to Appendix A of the NOFO for allowable activities.The Department of Homeland Security (DHS) has committed to bolstering the capacity of non-federal entities to receive noncitizens after they have been processed by U.S. Customs and Border Protection (CBP) and released from a DHS facility. DHS is committed to ensuring appropriate coordination with and support for state, local, and community leaders to help mitigate increased impacts to their communities as outlined in the DHS Plan for Southwest Border Security and Preparedness, issued on April 26, 2022, and updated on December 13, 2022.Applicants can submit applications for this funding opportunity through FEMA Grants Outcomes (GO). Access the system at https://go.fema.gov/.

This funding opportunity provides financial support for states, Tribes, irrigation districts, and nonprofit conservation organizations to restore aquatic ecosystems and improve biodiversity through various projects.

CSEPP is funded under the chemical demilitarization program, a major defense acquisition program executed by the Department of Defense. CSEPP augments the Armys Chemical Materials Activity (CMA), whose mission is to safely store the stockpile by ensuring maximum protection to its workers, the public, and the environment. CSEPP resides within the Technological Hazards Division (THD) of the National Preparedness Directorate of FEMA. FEMAs role is executed through a national office at FEMA Headquarters and the FEMA regional program offices where chemical installations are located.

The Water Resources Development Act (WRDA) of 2000 authorized the Comprehensive Everglades Restoration Plan (CERP) as a framework for modifications and operational changes to the Central and Southern Florida Project needed to restore the south Florida ecosystem. Provisions within WRDA 2000 provided for specific authorization for an adaptive assessment and monitoring program. The CEPP is a CERP project expected to provide an additional 370,000 acre-feet of freshwater to the Everglades annually. Freshwater fishes and invertebrates play a critical role at the base of the food chain within Everglades marshes, providing food to iconic apex predators like wading birds and alligators. Changes in water quantity and quality that influence freshwater fish and invertebrate assemblage structure directly influences wading bird ecology and ecosystem integrity of Everglades marshes. Monitoring of fishes and large invertebrates is necessary to track changes in water management associated with restoration projects both within Everglades National Park and upstream within the Water Conservation Areas. Long-term monitoring data are required to support assessment of the changes in water management. This project will conduct field sample collection, process samples, and data analyses and evaluate the long-term data set with regards to natural resource condition assessments. The CEPP Adaptive Management and Ecological Monitoring Plans identify the freshwater fish and macroinvertebrate communities as essential attributes of the ecosystem that need to be monitored to assess the influence of the CEPP and to confirm additional freshwater is improving the production and availability of aquatic fauna (fish and macroinvertebrates) to support higher tropic levels. This monitoring of aquatic fauna will inform CEPP Adaptive Management actions associated with CEPP performance in conjunction with other CERP projects and non-CERP operations. Program Description/Objective: (brief description of the anticipated work) The purpose of this research is to leverage a long-term dataset to monitor the status and trends of freshwater fish and macroinvertebrate populations at established sites within Water Conservation Area 3 (WCA3) in order to determine pre-CEPP implementation baseline conditions for aquatic fauna to inform CEPP Adaptive Management and Ecological Monitoring Plans The project objectives include: Objective 1: Collect samples to monitor status and trends of large (>8cm) and small (<8cm) freshwater fish and macroinvertebrate populations at 10-12 established sites in WCA3 up to 5 times intra-annually. Objective 2: Establish and report the baseline condition of aquatic faunal abundances and biomasses for future use in a Before, After, Control, Impact (BACI) assessment of CEPP project implementation. Objective 3: Demonstrate progress and present results in the form of quarterly status reports, annual reports, and a final report. Public Benefit This project will play a critical role in determining the effect of the CEPP on the aquatic fauna community in WCA3 and continue to build upon the knowledge base for understanding the ecology of the freshwater trophic community in the Greater Everglades ecosystem. Data collected will be used to inform the successful implementation of the CEPP and support the CERP in reaching its restoration goals and objectives. Understanding aquatic faunal dynamics within WCA3 is critical to assess and the effects of hydrologic changes associated with CEPP implementation, ecosystem restoration, and climate change which have potential impacts on the economy of South Florida, including tourism, recreational opportunities, and water management.