Grants for For profit organizations other than small businesses - Federal

In FY23, the OCRP established a new academy, the Ovarian Cancer Clinical Trial Academy (OCCTA), which will focus on clinical trial research in ovarian cancer. The intent of the OCCTA is to enhance knowledge within next generation of Early-Career Investigators (ECIs) in clinical trial research and to produce effective treatments and cures for ovarian cancer. The OCCTA will bring together established investigators (the Academy Dean and Assistant Dean), established Career Guides (mentors), and a group of ECIs/Scholars to conduct successful, highly productive clinical trials in ovarian cancer. The OCCTA strives to develop successful, highly productive ovarian cancer clinical trialists in a collaborative research and career development environment, providing intensive mentoring, national networking, collaborations, and a peer group for junior clinical trialists. The OCCTA, through its Leadership, provides for professional and leadership development of the ECIs to include skills and competencies needed to execute clinical trials.

This funding opportunity supports researchers in atmospheric science to utilize satellite data for advancing the understanding of precipitation, cloud dynamics, and related processes, particularly through the integration of legacy and current satellite missions.

This funding opportunity provides financial support for research projects that enhance data collection and analysis related to breast cancer, specifically targeting gaps in existing clinical studies and involving consumer advocates in the research process.

This funding opportunity supports projects that encourage low-income individuals to buy more fruits and vegetables by providing financial incentives through authorized retailers.

The "Puerto Rico Energy Resilience Fund: Resilient Communities Program" grant aims to use $1B in funding to enhance Puerto Rico's energy resilience and clean energy economy, particularly focusing on mitigating power outage impacts on low-income residents, ensuring energy reliability for healthcare services in disadvantaged communities, and supporting the growth of the clean energy workforce, through the installation of solar PV and battery storage in subsidized multi-family properties and community healthcare facilities.

The Department of States Office to Monitor and Combat Trafficking in Persons (TIP Office) is pleased to invite organizations to submit proposals to provide technical assistance focused on establishing survivor leadership and partnership structures in support of its global Training and Technical Assistance (T) Program. The Department of State’s Office to Monitor and Combat Trafficking in Persons (TIP Office) announces an open competition for projects to provide technical assistance focused on establishing survivor1 leadership and partnership structures 1 For simplicity and consistency, the terms “survivor” and “survivor leader” are used throughout this document. While some individuals who have experienced trafficking choose to embrace the title “survivor,” others do not. Terminology regarding human trafficking varies based on a country’s respective laws and language(s). The word “survivor” is not generally defined by law, nor is it in support of its global Training and Technical Assistance (T&TA) Program. The TIP Office manages foreign assistance programs dedicated to combating human trafficking outside of the United States. The TIP Office awards grants to combat all forms of human trafficking—sex trafficking, child sex trafficking, forced labor, domestic servitude, forced child labor, and the unlawful recruitment and use of child soldiers. The Department of State’s annual Trafficking in Persons Report (TIP Report) provides a diagnostic assessment of the efforts of governments to combat human trafficking and shapes our foreign assistance priorities. More information is available at: https://www.state.gov/international-programs-officeto-monitor-and-combat-trafficking-in-persons/. The TIP Office’s Training and Technical Assistance (T&TA) program aims to increase government and/or civil society capacity to combat human trafficking. T&TA is most appropriate for addressing specific knowledge or other capacity gaps through targeted, short-term interventions. The TIP Office can provide training and/or technical assistance on topics spanning all 4Ps – Prevention, Protection, Prosecution, and Partnership. T&TA interventions are most often initiated by requests from U.S. Embassies abroad, or sometimes from our T&TA implementing partners. The TIP Office reviews requests for T&TA on a rolling basis throughout the year. Selected T&TA requests are then referred by the TIP Office to the relevant implementer, depending on the type of assistance requested, the implementer’s areas of universally used or accepted in the context of human trafficking. In some countries, “survivor” may refer to those who have experienced historical, collective, or cultural trauma. Within the United States, there are some widely used terms for individuals who have experienced human trafficking and subsequently decided to engage in anti-trafficking related work on a professional level. Individuals may prefer to be referred to as “survivor leaders,” “survivor advocates,” or “subject matter experts with lived experience of human trafficking.” Some may have other titles or prefer not to identify based on this experience at all. In recognizing individuals’ full life experiences, skill sets, and professional goals, it is important to always ask someone how they want to be identified. Policymakers and stakeholders should not assume that someone who identifies as a “survivor leader,” “survivor advocate,” or “expert with lived experience of human trafficking” should be referred to as such in a professional setting or that identification as a survivor leader makes it acceptable to inquire about someone’s personal experience with human trafficking. expertise, and funding availability. The timeline to complete T&TA activities will depend on a variety of factors such as strategic priorities and country contexts. The selected implementer should be able to create an intervention concept note and budget in response to the specific T&TA request before the intervention is approved for implementation. The selected implementer should also expect to work closely with TIP Office staff throughout the development and implementation of interventions and activities. T&TA interventions can be standalone or they can lay the groundwork for or complement other programing, but they do not take the place of longer, multiyear programs. Individual T&TA interventions can sometimes also be structured in phases, with each phase being subject to TIP Office approval. T&TA activities may be conducted in countries across all regions of the world, so the scope of T&TA implementers’ capabilities must be global. The selected applicant should be able to respond to unanticipated requests for assistance in any country and/or region, with few exceptions. Some examples of what past T&TA interventions have looked like include the following: • Review of and edits to draft legislation or implementing regulations on a 24-hour turnaround; • Development and adoption of Foreign Government National Action Plan over the course of five months from receipt of request to final adoption; • Targeted technical assistance on the process to accede to United Nations Convention Against Transnational Organized Crime (UNTOC) and the Palermo Protocol; • Rapid diagnostic needs assessment on anti-trafficking capacity gaps of specialized anti-trafficking practitioners conducted within 4 weeks of initial request, followed by the development and delivery of a tailored training curriculum; • Tailored trainings delivered to law enforcement, prosecutors, and judges on how to build a human trafficking case in a country with limited resources and low capacity; • Tailored trainings delivered to shelter staff to improve identification, screening, and assistance of victims of trafficking, as well as technical assistance to develop necessary tools, such as screening forms and risk assessments; • Creation and implementation of a training series curriculum tailored to psychological and legal service providers to victims of trafficking in urban and rural locations both virtually and in-person, delivered over the course of several months; • Regional training for law enforcement and prosecutors, tailoring the materials to for applicability across various participating countries in the region. While some T&TA activities can be conducted remotely, and the ability to provide some programming virtually is an asset to the T&TA Program and to the selected implementers, the majority of T&TA activities are conducted in-person. Because T&TA interventions can take place in settings where utilities, such as internet connectivity, are unreliable, the TIP Office will not be able to consider applications whose model of T&TA delivery is entirely remote.

The U.S. Department of States Bureau of Democracy, Human Rights, and Labor (DRL), in coordination with the Bureau of International Narcotic and Law Enforcement Affairs (INL), announces an open competition for organizations interested in submitting applications for a professional development program to strengthen the practical skills and resiliency of anticorruption actors to combat corruption more effectively in Central America.

This funding opportunity is designed to establish a center that will coordinate and manage data for collaborative research on rare diseases, supporting various research consortia and engaging stakeholders to improve diagnosis and treatment.

This program funds projects that improve the safety, efficiency, and reliability of intercity passenger and freight rail. The Consolidated Rail Infrastructure and Safety Improvements (CRISI) Program is authorized under 49 U.S.C. 22907. The purpose of the CRISI Program is to invest in a wide range of projects within the United States to improve railroad safety, efficiency, and reliability; mitigate congestion at both intercity passenger rail and freight rail chokepoints to support more efficient travel and goods movement; enhance multi-modal connections; and lead to new or substantially improved Intercity Passenger Rail Transportation corridors. This program invests in railroad infrastructure projects that improve safety, support economic vitality (including through opportunities for small businesses), create good-paying jobs with the free and fair choice to join a union, increase capacity and supply chain resilience, apply innovative technology, and explicitly address climate change, gender equity and racial equity. The purpose of this notice is to solicit applications for the competitive CRISI Program provided in Consolidated Appropriations Act, 2023, division L, title I, Public Law 117–328 (2023 Appropriation), Consolidated Appropriations Act, 2024, division F, title I, Public Law 118–42 (2024 Appropriation) and the 2023 and 2024 advance appropriation in the Infrastructure Investment and Jobs Act, division J, title II, Public Law 117–58 (2021).

This ISO seeks solution summaries and proposals for projects that fall within the general scope of the ARPA-H Scalable Solutions mission office. SSO expands what is technically possible by developing approaches that will leverage an interdisciplinary approach and collaborative networks to address challenges of geography, distribution, manufacturing, data and information, thereby improving health care access and affordability. In the United States, many communities and remote areas lack access to timely and quality health care, which leads to disparities in health outcomes for those populations. Bottlenecks during the manufacturing processes of products and health technologies also lead to delays and limited availability, preventing effective distribution of health care solutions to areas of need, especially in emergencies.ARPA-H SSO seeks solutions to improve the scalability and affordability of health care solutions, bridge gaps in underserved areas, and extend remote access to expertise by developing location-specific interventions, telemedicine solutions, and mobile health clinics. Solutions should focus on rapid innovation and the use of partnerships, as well as flexible distribution networks and streamlined manufacturing processes. The following SSO interest areas categorize the ground-breaking solutions we seek to support:Scalable Technologies and Interventions: Approaches to improve affordability and equitable access to health care that are adaptable to various geographic, demographic, economic contexts and can be rapidly deployed at scale (e.g., drug-repurposing*, telemedicine, point-of-care diagnostics, and modular health care infrastructure). Tailored solutions for the pediatric population that provide parity in access to treatments and other health care interventions with the adult population and adapt to the pediatric patients changing physiology and developmental status over the course of years. Transformational approaches to reduce or eliminate health disparities, including tools and models for product design and care delivery that scale novel approaches in human factors and human-centered design to respond to full diversity of patients. Tools to enable the scaling of provider and institutional capabilities (e.g., school nurses and schools, walk-in clinics, homesteading care) to address unmet health care access needs and expand availability of critical services. Foundational capabilities to accelerate diagnoses and reduce the cost of treatments for rare diseases wherever patients are, without the need for specialized facilities or healthcare expertise.* Solution summaries and proposals that focus on testing drugs for effectiveness for other disease states or use cases, are unlikely to be funded unless including additional R, or providing gains in cost reduction, accessibility, and/or equity.Collaborative Distribution Networks: Methods for standardization, automation, and democratization of complex procedures 5 including, but not limited to, histopathology, rare disease diagnosis and treatment, and surgical interventions to ensure access and delivery to populations diverse in demographics, geographies, and resources at scale. Approaches to enhance delivery of effective healthcare solutions in rural or low resource settings, including but not limited to "last mile delivery, at-home monitoring, imaging, drug delivery, telehealth augmentation, and support for remote medical procedures with limited need for specialized training. Technologies to enable the deployment of critical healthcare resources rapidly, equitably, and securely at scale to the point of need in permissive and non-permissive (i.e., damaged infrastructure, cyber-denied) environments during a public health crisis or natural disaster. Solutions to scale education and training of critical healthcare resources for health care providers and patients to ensure information integrity to prevent negative impacts to resource use/uptake. Innovative information technology, data and analytic products and technologies to enable ordering, inventory management, situational awareness, allocation planning and demand forecasting of critical healthcare resources during a public health crisis or natural disaster.Biomanufacturing Innovations*: Innovative manufacturing technologies and approaches that reduce cost, shorten the timeline for production, advance domestic competitiveness and reduce supply chain risk of biologics, cellular and gene therapies, pharmaceuticals, medical devices and personal protective equipment. New approaches to support predictable, programable biological production of conventional and novel materials reliability at scale in a cost-effective sustainable manner. Novel solutions to reduce the reliance on specialized handling and cold chain management of pharmaceuticals and biologics. Scalable innovations to advance and strengthen biomanufacturing supply chain and resolve bottlenecks including:o Advances in production of active pharmaceutical ingredients, process consumables, and other critical materials (i.e., enzymes, cell lines, etc);o Novel biomanufacturing-related data products, technologies or models to integrate into supply chain situational awareness systems;o Alternative materials and new manufacturing capabilities for personal protective equipment; ando Improvement of capabilities sustainably re-shore manufacturing and utilize a broad array of readily accessible and cost-efficient feedstocks as part of strengthening the local and national industry base. Analytics and novel sensor systems to precisely manage bioproduction, real-time release assays, and predictive capabilities to inform tuning of biological chassis for efficient and effective scale-up of manufacturing to industrial scale.*ARPA-H is not interested in approaches that merely increase capacity reservation.Other high-quality submissions that propose revolutionary technologies that meet the goals of SSO will be considered even if they do not address the topics listed above.Proposals are expected to use innovative approaches to enable revolutionary advances in medicine and healthcare, and the science and technology underlying these areas. While approaches that are disease agnostic are encouraged, ARPA-H welcomes proposals that bring radically new insights to address specific diseases including, but not limited to, cancer, diabetes, neurological diseases, pediatric and maternal/fetal health, infectious diseases, and cardiovascular disease.Specifically excluded are proposals that represent an evolutionary or incremental advance in the current state of the art or technology that has reached the clinical trial stage. An example of this type of proposal might include the request to fund clinical trials of an otherwise developed product. Additionally, proposals directed towards policy changes, traditional education and training, or center coordination, formation, or development, and construction of physical infrastructure are outside the scope of the ARPA-H mission.

The purpose of this NIDCD initiative is to encourage research in the development, characterization, and reproducibility/reliability of human auditory and vestibular organoids.Applications investigating animal organoids are allowable but only if accompanying comparative or other integrated companion studies with human organoids. Singular animal organoid studies alone are not responsive to this funding opportunity. This funding opportunity encourages innovative, reproducible, and novel methodologies and technologies that will drive the reproducibility and holistic longevity of hearing/balance sensory organoids as model systems. The development of novel tools to deliver genes, proteins, molecules, and synthetics that might lead to the successful expansion and longer-term survivability of organoid populations in a stable, reliable, and reproducible manner is highly encouraged. Subsequent characterization of the organoid platforms must be shown to mimic and recapitulate the native correlative biological function. Applications that provide approaches that remove current barriers and lessen challenges to improve current reproducibility and stability are highly encouraged. Applications that have breakthrough approaches and technologies using human auditory/vestibular organoids are highly encouraged.

The GEL-ICS program will build a cohesive group of leaders working on issues in cyberspace who are committed to the UN-affirmed Framework of Responsible State Behavior and will be equipped with the necessary knowledge and global connections to be effective advocates and champions of the Framework through the fellowship and other activities.

This funding opportunity provides financial support to non-profits, local and tribal governments, and businesses for projects that promote renewable wood energy and innovative wood products, particularly in underserved communities and areas with high unemployment.

The NPS Chesapeake Gateways Tourism and Economic Development Grants aim to provide funding for projects that promote tourism and economic growth in the Chesapeake Bay area, with application details, FAQs, and training schedules available on their website, and additional information can be requested via email.

This funding opportunity supports early-career researchers in ovarian cancer clinical trials by providing financial resources, mentorship, and professional development through a specialized academy.

This funding opportunity provides financial support for U.S.-based organizations to conduct research on innovative construction technologies and policies that can help increase the availability of affordable housing nationwide.

The "U.S. Embassy Monrovia PDS Annual Program Statement" grant aims to fund programs by Liberian non-profit entities that strengthen U.S.-Liberian cultural ties and promote mutual understanding through activities such as lectures, workshops, cultural preservation, academic exchanges, and media training, all of which must include an American cultural element or connection.

This funding opportunity is designed for non-U.S.-based research entities to develop innovative AI technologies that improve maritime security through enhanced scene perception for unmanned vessels in complex marine environments.

The Public Affairs Section of the U.S. Embassy in Kuala Lumpur announces an open competition for a cooperative agreement to develop, organize, and oversee the 2025 Young Southeast Asian Leaders Initiative (YSEALI) Summit, pending the availability of funds. The four-day Summit (exclusive of arrival and departure dates) in 2025 will gather over 150 YSEALI exchange program alumni from across ASEAN countries and Timor-Leste. The award recipient is expected to design a youth-focused, high-energy, and dynamic Summit that will provide the next generation of Southeast Asian leaders the opportunity to build networks, discuss ideas, and develop solutions to contemporary challenges. The YSEALI Summit in Malaysia will be conducted in English. The content of the program should touch on each of the four pillars of YSEALI and include leadership, mentorship, and teamwork training. The Summit will enable participants to see how YSEALI members have become leaders in Southeast Asian communities through community service, entrepreneurship, civic engagement, and education. The Summit should feature panels and presentations by prior YSEALI participants from each country who have become changemakers in their fields. The Summit should feature sessions giving participants the opportunity to work together to develop possible solutions to current environmental, social, political, and economic challenges in the region. Participants should learn innovative approaches to promote relations among ASEAN countries and with the United States through presentation, case studies and simulations. The Summit will also provide leadership and other soft skills training on topics such as advocacy, negotiation, and personal branding, which are core soft skills YSEALI alumni need to become successful leaders. Participants will also have a chance to join cultural activities, and other site visits that support the Summits theme. The Summit will include a mix of informational sessions, discussions and challenges, and break-out sessions on different topics and group presentations, as well as site and cultural visits.

This grant provides funding and opportunities for companies and coalitions developing innovative energy storage solutions that enhance the integration of renewable energy systems and improve the efficiency of the electricity grid.