Grants for Native American tribal organizations - Federal

The "Innovation Grants to Nurture Initial Translational Efforts (IGNITE)" program supports the development of in vitro and ex vivo assays to identify and characterize new therapeutic agents for neurological and neuromuscular disorders, with a focus on creating robust screening methods for promising neurotherapeutics.

This funding opportunity supports exploratory preclinical studies to evaluate the effectiveness of therapeutic agents for rare diseases affecting fewer than 200,000 people in the U.S., aiming to advance these treatments toward clinical trials.

The "NIDCD's Mentoring Networks to Enhance Clinician-Scientists' Participation in Research" grant aims to support educational and mentoring activities that encourage individuals, especially those from diverse backgrounds, to pursue research careers in biomedical, behavioral, and clinical sciences, with a particular focus on improving the recruitment, preparation, and retention of clinician investigators.

This grant provides funding for advanced graduate students to conduct dissertation research in collaboration with Head Start programs, focusing on early childhood education for low-income families.

This grant provides funding to early-career researchers in mental health to support innovative projects that advance the understanding and treatment of mental illnesses.

The "Enhancing Criminal Justice Coordinating Councils Through Specialized Technical Assistance and Coaching" grant aims to support local criminal justice councils in implementing best practices for managing jail populations and reentry programs, using data-driven insights to improve operational efficiency and outcomes in the justice system.

This funding opportunity provides financial support for U.S. institutions and organizations to develop innovative methods for identifying and safely sealing undocumented orphaned oil and gas wells, thereby reducing methane emissions and environmental risks.

Under this Funding Opportunity Announcement (FOA), DOL will award grants through a competitive process to organizations providing pre-apprenticeship services that support education, occupational skills training, and employment services to opportunity youth, ages 16 to 24, who are performing meaningful work and service to their communities. The YouthBuild program model prepares participants for quality jobs in a variety of careers, in diverse industry sectors, particularly in infrastructure sectors, and includes wrap-around services such as mentoring, trauma-informed care, personal counseling, transportation supports, and employment preparation - all key strategies for addressing violence in communities. YouthBuild applicants must include construction skills training and may include occupational skills training in other in-demand industries. This expansion into additional in-demand industries is the Construction Plus component. Eligible applicants for these grants are public or private non-profit agencies or organizations, including consortia of such agencies or organizations. These organizations include rural, urban, or Native American/Tribal entities that have previously served opportunity youth in a YouthBuild or other similar program. DOL will fund approximately 75 projects across the country. Individual grants will range from $700,000 to $1.5 million and require a 25 percent match from applicants, using sources other than federal funding. This FOA features a matching waiver for Tribal entities and U.S. insular areas which allows these entities to not include a match commitment in their applications. The grant period of performance for this FOA is 40 months, including a four-month planning period and a twelve-month follow-up period.

"Fluctuating cognition can occur in many types of dementia and is a core clinical feature of Dementia with Lewy Bodies. Cognitive fluctuations can last from seconds to days, are unpredictable (e.g., do not just occur in the evenings, as with sun-downing), and are associated with poor daily functioning for the patient. A number of small studies have suggested that cognitive fluctuations in subjects with dementia may be related to epileptiform discharges and impaired oscillatory activity on EEG, but it is not clear that these are the only factors involved in patient populations that often experience dysautonomia, orthostasis, and sleep disturbances. The etiology of cognitive fluctuations may be multi-factorial and may vary in different dementia populations. Understanding the physiology related to cognitive fluctuations is a critical next step to the development of treatment approaches and improving quality of life for these patients. This initiate would encourage research that will better characterize the physiology responsible for cognitive fluctuations in ADRD populations. Given their variable appearance and time course, it is anticipated that wearable digital devices will be important for capturing fluctuations in a timely fashion, and applicants should consider incorporating those device(s) capable of acquiring the relevant data to support the hypothesized mechanism(s). Applicants may focus on assessing multiple mechanisms in a specific ADRD population, or may chose to compare mechanisms across multiple types of ADRDs. "

This funding opportunity provides financial support to community-based organizations partnering with local governments or educational institutions to implement projects that address environmental and climate challenges in disadvantaged communities across the U.S.

Grant Title: Artificial Intelligence and Machine Learning Applied to Nuclear Science and Technology - This grant aims to fund research that uses AI and machine learning to improve the efficiency and effectiveness of nuclear science experiments, particularly in optimizing accelerators, detectors, and data analysis.

This funding opportunity supports research on the ethical, legal, and social implications of human genetics and genomics, particularly focusing on diverse perspectives and community engagement.

This funding opportunity provides financial support for conservation projects that engage youth in hands-on work experiences and skills development related to public lands and natural resource management, with a focus on promoting equity and climate resilience.

This funding opportunity supports early-stage postdoctoral researchers in cancer research by providing resources for structured training and professional development to advance their scientific careers.

(Reissue PAR-21-056) The purpose of this Program Announcement (PAR) is to enable analytical validation of strong candidate biomarkers for neurological diseases and conditions. Specifically, the goal of this PAR is to enable the rigorous validation of analytical methods for biomarker measurements, including evaluation of the detection method, its performance characteristics, and the optimal conditions that will generate reproducibility and accuracy consistent with FDA guidelines. This PAR assumes that 1) a candidate biomarker has already been identified, 2) detection method technology has already been developed, and 3) the research and/or clinical need and potential context of use has been identified.

The Division of Ocean Sciences (OCE) at the National Science Foundation (NSF) requests proposals from eligible U.S. institutionsto provide aScientific Ocean Drilling Coordination Office(SODCO). This Coordinating Office will work with Principal Investigators (PIs) in the selection of suitable, academically or commercially available drilling and coring platforms to collect subseafloor samples, make subseafloor measurements, and install long-term borehole observatories. It is anticipated that SODCO will be supported by the NSF Ocean Drilling Program (ODP) through a Cooperative Agreement of up to five years duration with the possibility of renewal for up to an additional five years. SODCO may work with the commercial drilling community or other drilling organizations from the United States or abroad to determine the type and availability of drilling platforms and services that may be available for NSF-funded scientific projects that require ocean drilling. SODCO will have the expertise to generate requests for bids to provide the drilling services as needed. SODCO is expected to play a proactive role in the ocean science community to encourage innovation in drilling technologies and methods in response to scientific community needs and will help guide the development of new drilling designs as requested by the ocean science community. SODCO will coordinate and manage drilling activities for the U.S. ocean science community. Requirements for drilling activities will be derived both from long-range science plans developed by the ocean science community as well as research proposals funded by NSF. We encourage collaborations with international partners and with scientists funded by other sources. SODCO will be capable of assisting in the planning and execution of all aspects of the drilling activities. Interested parties must respond to this solicitation with a proposal to provide for these services under a single award. SODCO award will be administered as a Cooperative Agreement with an anticipated duration of up to five-years. A mid-term management review will be required, which will guide a decision to re-compete or renew the Cooperative Agreement for up to a further five-year period. SODCOs role is expected to be coordination and management of activities for proponents seeking to develop a deep-sea drilling program; financial support for a specific drilling expedition, including lease of a specific platform will be through another award instrument. It is expected that provision of expedition-specific platforms will therefore be accomplishedearly in the science proposal development process in collaboration with individual proponents that intend to establish a drilling-based research program.

DEMD administers the EMDP grant. This solicitation seeks proposals for projects that conduct resource inventories and assessments, feasibility studies, or other pre-development studies necessary to process, use and develop energy and mineral resources. These resources and their uses include, but are not limited to, biomass (woody and waste) for heat or electricity; transportation fuels; hydroelectric, solar, or wind generation; geothermal heating or electricity production; district heating; other forms of distributed energy generation; oil, natural gas, and helium; sand and gravel, coal, precious minerals, and base minerals (lead, copper, zinc, etc.).EMDP projects may include, but are not limited to:Initial resource exploration;Defining potential targets for development;Performing a market analysis to establish production/demand for a commodity;Performing economic evaluation and analysis of the resource;Baseline studies related to energy and mineral projects; andOther pre-development studies or work necessary to promote the use and development of energy and mineral resources.

This grant provides funding for researchers to study how HIV and substance use disorder affect brain cell function, with the goal of uncovering new treatment strategies for individuals facing these combined challenges.

This funding opportunity supports multi-disciplinary research projects aimed at developing effective HIV/AIDS vaccines through advanced studies and preclinical evaluations in animal models.

This funding opportunity supports researchers in conducting multi-site clinical trials to investigate the effects of natural products, such as botanicals and dietary supplements, on health, requiring a comprehensive plan for trial management and data analysis.