Grants for Native American tribal organizations - Federal

Questions regarding this Funding Opportunity Announcement (FOA) Forecast may be emailed to SCSEP.OGM@dol.gov; however, please note there is limited information that may be shared with the public, as this FOA is currently under development. We encourage prospective applicants and interested parties to use the Grants.gov subscription option to register for future updates provided for this particular FOA.

This funding opportunity supports innovative clinical research to explore the brain mechanisms behind substance use disorders, targeting a wide range of researchers and institutions dedicated to addressing addiction challenges.

The National Institute on Drug Abuse (NIDA) Cutting-Edge Basic Research Award (CEBRA) is designed to foster highly innovative or conceptually creative research related to the etiology, pathophysiology, prevention, or treatment of substance use disorders (SUDs). It supports high-risk and potentially high-impact research that is underrepresented or not included in NIDA's current portfolio that has the potential to transform SUD research. The proposed research should: 1. develop, and/or adapt, revolutionary techniques or methods for addiction research or that show promising future applicability to SUD research; and /or 2. test an innovative and significant hypothesis for which there are scant precedent or preliminary data and which, if confirmed, would transform current thinking.

This funding opportunity provides financial support to accredited dental and dental hygiene education institutions to create loan repayment programs that encourage faculty recruitment and retention, addressing faculty shortages in the dental field.

This funding opportunity provides financial support to cultural institutions like museums and libraries to implement environmentally sustainable strategies for preserving their collections and improving storage conditions.

This program provides funding to federally recognized Indian Tribes to improve road safety and reduce traffic-related injuries and fatalities on tribal lands.

This funding opportunity provides financial support for researchers to analyze and integrate existing data to better understand cancer risk, prevention, and treatment outcomes, particularly focusing on innovative methodologies and addressing health disparities.

This ISO seeks solution summaries and proposal submissions for projects that fall within the general scope of the ARPA-H Health Science Futures (HSF) mission office. HSF expands what is technically possible by developing approaches that will remove the scientific and technological limitations that stymie progress towards the healthcare of the future. HSF supports cutting-edge, often disease-agnostic research programs that have the potential for translational real-world change.Considering the current healthcare challenges that we face today, the goal of achieving better health outcomes is a moving target that requires daring and adaptable solutions. HSF awardees will develop innovative technologies, tools, and platforms that can be applied to a broad range of diseases. The following interest areas define the ground-breaking research we seek to support:Breakthrough Technologies: Paradigm shifting technologies that will change how we approach the diagnosis, treatment, and impact of diseases and conditions. Novel approaches to improve maternal and fetal medicine, decrease maternal morbidity and mortality during birth, and the post-partum period. Efforts should include new technology to monitor, detect, and/or treat maternal and/or fetal complications with less invasive and traumatic methods. Foundational advances in genetic, epigenetic, cellular, tissue, and organ replacement therapies that enable personalized medical interventions at scale in a manner that is accessible, cost-effective, and designed to impact the communities of greatest need. Interventions that target and reverse disease pathogenesis and/or enhance plasticity to address diseases of the nervous, neuromuscular, skeletal, lymphatic, cardiovascular, and other organ systems. Novel approaches to diagnose and treat diseases of the lymphatic system, particularly rare diseases, with a focus on the effects of genetic expression in the lymphatic system and/or models demonstrating the relationship between lymphatic dysfunction and health and disease.Transformative Tools: Novel, agile solutions that will move from bench to bedside quickly, facilitating revolutionary advances in medical care. Development of tools that counter idiosyncratic, off-target, or chronic effects of medicines that are commonly used or that are being used experimentally to treat or prevent disease. Development of bionics to restore sight, hearing, taste, or smell. Site-selective neuromodulation to regulate specific physiological functions and treat chronic health conditions such as inflammation, pain, and metabolic or endocrine disorders. Synthetic biology approaches to diagnosing, treating, and/or curing a multitude of diseases. Novel physics and/or chemistry-based approaches to improve imaging that reduces cost, increases availability, expands capability, improves resolution, reduces exposure to radiation, and accommodates pediatric patient populations. Integrated sensing and delivery devices for treating and diagnosing chronic health conditions, including mental health conditions or substance use disorders. Miniaturization of complex hardware to enable broader access to pediatric and other patient populations, as well as portability, such as diagnostic, treatment, imaging, or other devices.Platform Systems: Adaptable, multi-application systems and technologies that are reconfigurable for a wide variety of clinical needs Novel molecular platform approaches, including the modulation of host systems, delivery to targets with spatial and temporal precision, and mitigation of off-target effects to accelerate interventions that dramatically improve health outcomes. New approaches to accelerate and routinize mammalian and microbial cellular engineering to enable next generation therapeutic applications, develop multiscale interventions, and automate hypothesis generation and discovery to expand those applications to disease states in which cellular therapies have not traditionally been employed. Innovative approaches at the intersection of artificial intelligence, high performance computing (including quantum computing) and biological systems, including enabling de novo design of biomolecules with entirely new phenotypes.Other high-quality submissions that propose revolutionary technologies that meet the goals of HSF will be considered even if they do not address the topics listed above.Proposals are expected to use innovative approaches to enable revolutionary advances in medicine and healthcare, and the science and technology underlying these areas. While approaches that are disease agnostic are encouraged, ARPA-H welcomes proposals that bring radically new insights to address specific diseases including, but not limited to, cancer, diabetes, neurological diseases, pediatric and maternal/fetal health, infectious diseases, and cardiovascular disease.Specifically excluded are proposals that represent an evolutionary or incremental advance in the current state of the art or technology that has reached the clinical trial stage. An example of this type of proposal might include the request to fund clinical trials of an otherwise developed product. Additionally, proposals directed towards policy changes, traditional education and training, or center coordination, formation, or development, and construction of physical infrastructure are outside the scope of the ARPA-H mission.

This funding opportunity supports researchers transitioning to data science in substance use and addiction studies, enabling innovative projects that leverage advanced analytical techniques to improve public health outcomes.

With this solicitation, OJJDP seeks to support state, local, and Tribal juvenile justice residential facilities, and the agencies that oversee them, with the recruitment and retention of staff to assist in complying with the staffing ratio requirements outlined in the national PREA standards. This solicitation prioritizes efforts to create and enhance a sexually safe culture, promoting zero tolerance of sexual abuse in juvenile facilities. This program furthers the DOJs mission to uphold the rule of law, to keep our country safe, and to protect civil rights.

With this solicitation, BJA seeks to support new and innovative strategies for preventing and reducing crime, improving community safety, and strengthening criminal justice system outcomes. BJA seeks to accomplish this by promoting collaborations with the field to identify, define, and respond to emerging or chronic crime problems or justice system challenges. BJA is looking for strategies that address these issues, including trying new approaches, addressing gaps in responses, building or translating research knowledge, or building capacity.

This funding opportunity supports multidisciplinary research aimed at improving the understanding and treatment of asthma and allergic diseases, inviting applications from various institutions and organizations involved in clinical and translational research.

This grant provides funding to specialized clinics for collecting and analyzing long-term health data on individuals with spina bifida, aiming to improve care and health outcomes for patients of all ages.

This grant provides funding to support research and initiatives that promote diversity, equity, inclusion, and accessibility for individuals with disabilities in STEM fields and education.

This funding opportunity supports innovative research projects that explore how T-cells contribute to HIV infection and related brain complications, targeting researchers from various institutions and organizations.

This funding opportunity supports innovative educational projects that engage K-12 students and teachers in the biomedical and behavioral sciences, particularly targeting individuals from diverse and underrepresented backgrounds.

The purpose of the Paul Calabresi Career Development Award for Clinical Oncology (PCACO) is to increase the number of clinician-scientists trained in clinical and translational cancer research, and to promote their career development as cancer researchers. This Funding Opportunity Announcement (FOA) allows appointment of Scholars proposing to serve as the lead investigator of an independent clinical trial; or proposing a separate ancillary study to an existing trial; or proposing to gain research experience in a clinical trial led by another investigator, as part of their research and career development.

The Blueprint Neurotherapeutics Network for Biologics (BPN-Biologics) provides support for biologic-based therapeutic discovery and development, from lead optimization through phase I clinical testing. This Funding Opportunity Announcement (FOA) supports preclinical discovery and development of potential therapeutic Biotechnology Products and Biologics including, but not limited to, large biologic macromolecules, (e.g., proteins, antibodies, and peptides), gene-based therapies (i.e., oligonucleotide- and viral-based), cell therapies, and novel emerging therapies (e.g., microbial and microbiome therapies). Applicants will collaborate with NIH-funded consultants and can augment their project with NIH contract research organizations (CROs) that specialize in manufacturing, scaling, pharmacokinetics, toxicology, and Phase I clinical testing. BPN-Biologics awardee institutions retain their assignment of IP rights and gain assignment of IP rights from the BPN-Biologics contractors (and thereby control the patent prosecution and licensing negotiations) for biotherapeutic candidates developed in this program.

This cooperative agreement would establish a Center for Home-based Child Care Research to support research about home-based child care (HBCC) in states, territories, This cooperative agreement would establish a Center for Home-based Child Care Research to support research about home-based child care (HBCC) in states, territories, tribes, and/or local community contexts. The purpose of the Center is to provide leadership, build research capacity in the field, and offer support in the development and facilitation of local research to improve understanding of HBCC settings and providers as well as access by the families who seek and utilize HBCC. This research center would promote sound research examining HBCC supply and the factors that support or suppress the availability of HBCC in communities. In addition, this Center would advance the fields understanding of HBCC engagement in public programs and quality improvement efforts. The Centers activities would build research and evaluation capacity in the field and support research in states, territories, and/or tribes that could inform local initiatives designed to sustain and strengthen HBCC.HBCC providers, or individuals and small business owners paid to provide child care in private residences or homes, are an essential segment of the child care landscape. They constitute the largest portion of the child care and early education (CCEE) workforce and serve the vast majority of children birth through school-age who are in regular nonparental care. It is critical for the Administration for Children and Families and for local communities to learn more about HBCC providers, both the individuals providing the care and the characteristics of the programs where they provide child care, in order to inform federal efforts and state, territory, tribal and/or local initiatives to increase access to safe and high-quality child care particularly for families with lower-incomes and working families. The Center would promote sound research examining HBCC and the factors that support or suppress the availability of HBCC in states, territories, and/or tribes. In addition, this Center would advance the fields understanding of HBCC providers engagement in publicly funded programs (e.g., child care subsidies, Head Start) and quality improvement efforts (e.g., Quality Rating and Improvement Systems (QRIS), quality initiatives (QI), and continuous quality improvement (CQI) initiatives). The Centers activities would build research and evaluation capacity in the field and support research in state, territories and/or tribes that could inform local initiatives designed to sustain and strengthen the supply of HBCC. This Center would ideally bring together a team that has experience investigating HBCC, evaluating Child Care and Development Fund (CCDF) program and policies, and assessing the needs and experiences of families with lower-incomes, in tribal communities, and of historically marginalized populations. This Center would be equipped to strengthen the ability of local research partnerships to conduct model research projects that effectively address questions concerning HBCC in local contexts, while contributing to broader understanding in the field about HBCC.

This funding opportunity supports small pilot projects that enhance understanding of the human virome, inviting collaborations from various organizations, including educational institutions and nonprofits, to develop innovative tools and methods for studying the interactions between viruses and human health.