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Grants for Nonprofits - Federal

Explore 6,598 grant opportunities

Office of Elementary and Secondary Education (OESE): Well-Rounded Education Programs: Jacob K. Javits Gifted and Talented Students Education (Javits) Program
$650,000
U.S. Department of Education
Federal

Application Deadline

Jun 23, 2026

Date Added

Apr 23, 2026

This funding opportunity provides financial support to educational agencies and organizations to develop innovative strategies for identifying and serving gifted and talented students, particularly those from underserved backgrounds.

Education
State governments
AFCEC Land Management Mapping for CONUS/Europe/PACAF Air Force Installations
$59,332,041
U.S. Department of Defense (Fort Worth District)
Federal

Application Deadline

May 26, 2026

Date Added

Apr 24, 2026

This funding opportunity is designed to support organizations involved in environmental conservation and land management by providing resources for geospatial data collection and analysis across U.S. Air Force installations in the continental U.S., Europe, and the Pacific.

Natural Resources
Public and State controlled institutions of higher education
Lewis Houghton Civics and Democracy Initiative - Continuing Awards
$250,000
Library of Congress
Federal

Application Deadline

May 18, 2026

Date Added

Apr 21, 2026

This funding opportunity provides financial support to existing partner organizations of the Library of Congress to enhance and expand civic education programs using the Library's digital collections.

Education
Nonprofits
Innovative Health Practices
$1,000,000,000
U.S. Agency for International Development
Federal

Application Deadline

Feb 20, 2028

Date Added

Feb 21, 2023

The United States Agency for International Development (USAID) is issuing this Broad Agency Announcement (BAA) to seek participants to co-create, co-design, co-invest, and collaborate on creating, piloting, and scaling innovative research and development interventions utilizing innovative health practices to help reduce disease and mortality rates worldwide. USAID invites organizations and companies to submit an Expression of Interest (EOI) and participate in generating novel tools and approaches that accelerate and sustain improved health outcomes in low-and-middle-income countries (LMICs). The intent of the BAA is to allow co-creation and co-design to the maximum extent to create high quality, effective partnerships with great efficiency in time and resources. USAID is seeking new applications of research development, science, partnerships, and innovative practices in global health that provide the best value to the Government. USAID will invite selected for-profit and non-profit, public and private organizations, as detailed below, to co-create innovative research and development (R) solutions to the Problem and Challenge Statements stated in this BAA, including those organizations that have ideas, expertise, resources, and/or funding to add to potential solutions. In particular, this BAA welcomes co-creation from local partners based in LMICs, including the private sector, faith-based organizations, and other non-traditional USAID partners, to increase the presence and voices of local populations in solving their own health challenges.The intent of the BAA is to enable and encourage co-creation and co-design in order to generate high quality ideas and effective partnerships with improved efficiency in time and resources. Other types of collaboration can also include co-investing:Co-Investing: USAID wants to align goals with the partners under this BAA, to facilitate shared responsibility, shared risk, and shared resourcing. Shared resourcing requires that cash and other resources, both tangible and intangible, such as in-kind contributions, expertise, intellectual property, brand value, high-value coordination, and access to key people, places, and information, are directed towards reaching the solution to the Problem/Challenge. Co-investing does not require equal shared resources (such as 1:1 leverage), but rather resource contributions that are appropriate to the specific projects objectives, considering the comparative advantages brought by the participation of each party.

Science and Technology
Nonprofits
Molecular Imaging of Inflammation in Cancer (R01 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 5, 2024

Date Added

Jul 22, 2021

This funding opportunity invites researchers to develop and apply advanced imaging techniques to better understand the role of inflammation in cancer, fostering collaboration between cancer scientists and imaging experts.

Education
State governments
T32 Training Program to Promote Broad Participation (T32 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Feb 4, 2025

Date Added

Jan 17, 2025

This funding opportunity supports research training for underrepresented students and health professionals in cardiovascular, pulmonary, hematologic diseases, and sleep disorders, aiming to increase diversity in the biomedical research workforce and reduce health disparities.

Health
State governments
NIA Renewal and Revision Cooperative Agreements in AD/ADRD Research (U24 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 25, 2024

Date Added

Feb 3, 2022

This Funding Opportunity Announcement (FOA) allows for renewal and competitive revision applications, and their resubmissions, for funded U24?Research Resource/Infrastructure?applications?that?support?large-scale, complex research programs focused on?Alzheimers disease (AD) and?Alzheimers disease-related dementias (ADRD).?It is anticipated that such programs will likely involve a team of investigators within a single institution or a consortium of?institutions?and?align with one or more?AD/ADRD implementation research milestones?supporting the?research goals of the??National Plan to Address Alzheimers and Related Dementias.

Health
State governments
Bolstering Security and Defense
$15,000
U.S. Department of State (U.S. Mission to Luxembourg)
Federal

Application Deadline

May 4, 2025

Date Added

Dec 19, 2024

This funding opportunity supports U.S. and Luxembourgish organizations in initiatives that strengthen security and defense collaboration, focusing on NATO, countering misinformation, and enhancing cybersecurity efforts.

International Development
Nonprofits
FY 2024 Teams Engaging Affiliated Museums and Informal Institutions (TEAM II) STEM Innovator Award
$250,000
National Aeronautics & Space Administration
Federal

Application Deadline

Sep 26, 2024

Date Added

Jul 2, 2024

The FY 2024 Teams Engaging Affiliated Museums and Informal Institutions (TEAM II) STEM Innovator Award is a grant offered by NASA's Next Gen STEM Project, aimed at supporting informal education organizations and libraries in providing NASA-aligned, inquiry-based STEM educational opportunities to students and educators, with the goal of expanding their regional reach, enhancing innovative practices, and benefiting diverse local communities.

Education
Nonprofits
AI3 Action Institute - Artificial Intelligence for American Indians
$3,500,000
U.S. Department of Health and Human Services (Administration for Children and Families - ANA)
Federal

Application Deadline

Aug 27, 2026

Date Added

May 7, 2026

This funding opportunity provides resources to Native American communities and organizations to establish a national institute focused on the responsible use and governance of artificial intelligence technologies for socioeconomic development and cultural alignment.

Opportunity Zone Benefits
Native American tribal organizations
Cooperative Agreement for affiliated Partner with the Great Lakes Northern-Forest Cooperative Ecosystem Studies Unit
$299,971
U.S. Department of the Interior (Geological Survey)
Federal

Application Deadline

Jun 29, 2026

Date Added

Nov 27, 2025

This funding opportunity provides financial support for institutions involved in scientific research and conservation efforts to restore native mussel populations in the Great Lakes region, specifically targeting the Indiana Dunes National Park.

Science and Technology
Public and State controlled institutions of higher education
NIDA Animal Genomics Program (U01 Clinical Trial Not Allowed)
Contact for amount
Department of Health and Human Services - National Institutes of Health
Federal

Application Deadline

Jul 26, 2024

Date Added

Jun 24, 2024

The purpose of the NIDA Animal Genetics Program is to identify genetic, genomic, and molecular (epi)genetic variants that underlie: 1. Phenotypes associated with addictive behaviors and/or vulnerability to distinct stages along the substance use disorder (SUD) trajectory (e.g. initial/acute use, escalation of use, acquisition of tolerance, dependence, uncontrolled use, abstinence and relapse or recovery); 2. Behaviors associated with SUD (e.g. impulsivity, novelty seeking, delayed discounting, and other genetically-associated phenotypes); and 3. Comorbidities that demonstrate genetic correlations with phenotypes and behaviors linked with SUD (e.g. anxiety, stress, poor maternal care, social defeat, and other paradigms). Applications may examine any type of variant, including single nucleotide variants (SNVs), indels, large and small structural variants, and all types of mobile DNA. NIDA encourages applications that take genomics, multi-omics, and/or data-based approaches that integrate multi-level omics data, delineate gene networks, and/or uncover the function of known or newly discovered genetic or epigenetic variants. NIDA expects these studies to uncover novel mechanisms that contribute to SUD and facilitate the discovery of targets for intervention and guide the development of individualized therapeutics to treat these different aspects of SUD.

Education
State governments
Monitoring, Operations Research, Evaluation of Tools for Malaria Control and Prevention in Kenya
$3,000,000
U.S. Department of Health & Human Services (Centers for Disease Control and Prevention - ERA)
Federal

Application Deadline

Feb 12, 2025

Date Added

Aug 7, 2024

This funding opportunity provides financial support for research and evaluation projects aimed at improving malaria control and prevention strategies in Kenya, specifically targeting collaborations with local health institutions.

Health
State governments
Comprehensive Addiction and Recovery Act (CARA)
$75,000
U.S. Department of Health and Human Services (Centers for Disease Control - NCIPC)
Federal

Application Deadline

Jun 8, 2026

Date Added

Feb 20, 2026

This funding opportunity provides financial support to community coalitions focused on preventing and reducing opioid and methamphetamine use, as well as prescription drug misuse among youth aged 12 to 18 in areas experiencing higher-than-average substance misuse rates.

Health
Nonprofits
EXPRESS:2025 Exploratory Research for Extreme-Scale Science
$1,000,000
U.S. Department of Energy (Office of Science)
Federal

Application Deadline

May 6, 2025

Date Added

Jan 21, 2025

This funding opportunity provides financial support for innovative research in advanced scientific computing and extreme-scale science, targeting a wide range of applicants including universities, for-profit companies, and federal laboratories, to tackle challenges in high-performance computing, quantum technologies, and artificial intelligence.

Science and Technology
Nonprofits
National Communication System for Runaway and Homeless Youth Program
$1,800,000
U.S. Department of Health and Human Services (Administration for Children ; Families - ACYF/FYSB)
Federal

Application Deadline

Aug 19, 2026

Date Added

Apr 28, 2026

This funding opportunity provides financial support to nonprofit organizations and government entities to establish a nationwide communication system that assists runaway and homeless youth by connecting them with crisis intervention services and resources.

Income Security and Social Services
Nonprofits
Limited Competition: Small Grant Program for NIAMS K01, K08, K23, and K25 Recipients (R03) (Clinical Trials Not Allowed)
$100,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Feb 19, 2025

Date Added

Dec 10, 2024

This funding opportunity provides financial support to early-career researchers who have received specific NIAMS awards, enabling them to conduct small-scale studies and gather data to advance their research and secure future funding.

Health
State governments
NSF Boosting Research Ideas for Transformative and Equitable Advances in Engineering
$600,000
National Science Foundation
Federal

Application Deadline

Mar 3, 2025

Date Added

Nov 26, 2024

This grant provides funding for experienced researchers at U.S. higher education institutions to explore new engineering fields or reestablish their research after a break, with a focus on innovation, societal impact, and promoting diversity and inclusion.

Science and Technology
Nonprofits
DoW Prostate Cancer, Data Science Award
$1,400,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Sep 2, 2026

Date Added

May 6, 2026

This funding opportunity supports researchers and organizations using data science to analyze complex prostate cancer datasets, aiming to improve patient outcomes and advance scientific knowledge in the field.

Science and Technology
Nonprofits
ProCON Global
$10,000,000
DOS-CDP (Bureau of Cyberspace and Digital Policy)
Federal

Application Deadline

Jul 15, 2024

Date Added

May 22, 2024

The overall goal of ProCON Global is to promote open, interoperable, reliable, and secure commercial undersea cable systems around the world. The project will provide technical assistance to key decision-makers, including policymakers, regulators, and technology companies in emerging economies, to promote evaluation processes and investment in secure and trusted vendors when establishing undersea cable network supply chains. Technology companies include telecommunications operators/carriers, major technology and security firms, innovators, and content and cloud providers.

Science and Technology
Nonprofits