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Grants for Nonprofits - Federal

Explore 6,598 grant opportunities

Formative and Pilot Intervention Research to Optimize HIV Prevention and Care Continuum Outcomes (R34 Clinical Trial Optional)
$225,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 9, 2025

Date Added

Jan 10, 2023

This grant provides funding for research projects that develop and test new strategies to improve HIV prevention and treatment outcomes, particularly by involving communities affected by HIV.

Health
State governments
Alfalfa Seed and Alfalfa Forage Systems
$900,000
U.S. Department of Agriculture (National Institute of Food and Agriculture)
Federal

Application Deadline

Jun 12, 2026

Date Added

Apr 29, 2026

This program provides funding to support research and extension projects that improve alfalfa seed and forage production systems, benefiting farmers, ranchers, and agricultural institutions across the U.S.

Agriculture
Public and State controlled institutions of higher education
Ending the Epidemic: New Models of Integrated HIV/AIDS, Addiction, and Primary Care Services (R34 Clinical Trial optional)
$450,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 27, 2024

Date Added

Jul 19, 2023

This funding opportunity is designed to support research that develops and tests new ways to integrate HIV/AIDS, Hepatitis, and substance use disorder prevention and treatment services to improve health outcomes for individuals at high risk or living with these conditions in the U.S.

Education
State governments
Strengthening the Medical Examiner-Coroner System Program
$300,000
U.S. Department of Justice (Bureau of Justice Assistance)
Federal

Application Deadline

Oct 14, 2025

Date Added

Sep 12, 2025

This funding opportunity provides financial support to medical examiner and coroner offices for accreditation and to develop forensic pathology fellowships, addressing workforce shortages and improving death investigation standards nationwide.

Law Justice and Legal Services
State governments
NIJ FY25 Research and Development in Forensic Science for Criminal Justice Purposes
$12,500,000
U.S. Department of Justice (National Institute of Justice)
Federal

Application Deadline

Apr 2, 2025

Date Added

Jan 17, 2025

This funding opportunity provides financial support for research and development projects that improve forensic science practices and technologies, targeting a wide range of eligible entities including government agencies, educational institutions, and nonprofit organizations.

Science and Technology
State governments
Preventing global health threats by strengthening surveillance systems to accelerate outbreak detection, notification, and response
$1,500,000
U.S. Department of Health and Human Services (Centers for Disease Control-GHC)
Federal

Application Deadline

Jul 15, 2026

Date Added

Sep 19, 2025

This funding opportunity provides financial support to a wide range of organizations, including governments and nonprofits, to strengthen global health surveillance systems for faster detection and response to infectious disease outbreaks in various regions around the world.

Health
State governments
Sustaining HIV services for key and priority populations through enhanced differentiated testing, innovative treatment and prevention approaches, and continuous support to Ukraine Ministry of Health, Public Health Center, and communities under PEPFAR
$8,000,000
U.S. Department of Health & Human Services (Centers for Disease Control-GHC)
Federal

Application Deadline

Feb 21, 2025

Date Added

Aug 8, 2024

This grant provides funding to organizations in Ukraine to improve HIV testing, prevention, and treatment services for vulnerable populations affected by the ongoing war.

Health
State governments
Research Projects to Enhance Applicability of Mammalian Models for Translational Research (R01 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 5, 2024

Date Added

Aug 18, 2023

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) invites applications for projects to expand, improve, or transform the utility of mammalian cancer and tumor models for translational research. With this NOFO, the NCI intends to encourage submission of projects devoted to demonstrating that mammalian models or their derivatives used for translational research are robust representations of human biology, are appropriate to test questions of clinical importance, and provide reliable information for patients' benefit. These practical goals contrast with the goals of many mechanistic, NCI-supported R01 projects that employ mammals, or develop and use mammalian cancer models, transplantation tumor models, or models derived from mammalian or human tissues or cells for hypothesis-testing, non-clinical research. Among many other possible endeavors, applicants in response to this FOA could propose demonstrations of how to overcome translational deficiencies of mammalian oncology models, define new uses of mammalian models or their genetics for unexplored translational challenges, advance standard practices for use of translational models, test approaches to validate and credential models, or challenge current practices for how models are used translationally

Education
State governments
BJS FY25 National Victimization Statistical Support Program (NVSSP)
$2,000,000
U.S. Department of Justice (Bureau of Justice Statistics)
Federal

Application Deadline

Feb 10, 2026

Date Added

Jan 16, 2026

This funding opportunity provides financial support for research and statistical analysis related to crime and victimization, primarily aimed at enhancing the National Crime Victimization Survey and its methodologies.

Information and Statistics
Independent school districts
Energy Frontier Research Centers (EFRCs)
$18,000,000
U.S. Department of Energy (Office of Science)
Federal

Application Deadline

Jul 1, 2026

Date Added

Feb 18, 2026

This funding opportunity supports interdisciplinary research teams in the U.S. to conduct foundational studies in energy, environment, and national security, fostering scientific innovation and training the next generation of energy-focused researchers.

Science and Technology
State governments
Marine Mammal and Habitat Monitoring-Cook Inlet Beluga Whale Prey at Joint Base Elmendorf-Richardson (JBER)
$522,500
U.S. Department of Defense (Fort Worth District)
Federal

Application Deadline

May 4, 2026

Date Added

Apr 3, 2026

This funding opportunity is designed for organizations involved in marine mammal research to study and monitor the endangered Cook Inlet beluga whale and its habitat near Joint Base Elmendorf-Richardson in Alaska.

Natural Resources
Public and State controlled institutions of higher education
Tissue Chips in Space 2.0: Translational Multi-Organ Tissue Chip Systems for Drug Efficacy, Toxicity Testing, and Personalized Medicine in Human Health, Aging and Associated Diseases (UG3/UH3 Clinical Trial Not Allowed)
$750,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 18, 2024

Date Added

Jul 26, 2024

The "Tissue Chips in Space 2.0" grant aims to fund the development of automated miniaturized systems that mimic human organs, to study the effects of space conditions on human health, aging, and diseases, using a diverse range of human samples for more accurate modeling and intervention development.

Health
State governments
BRAIN Initiative: Targeted BRAIN Circuits Projects- TargetedBCP (R01 Clinical Trial Not Allowed)
Contact for amount
HHS-NIH11 (National Institutes of Health)
Federal

Application Deadline

Feb 13, 2024

Date Added

Feb 10, 2022

(Reissue of RFA-NS-18-030) This FOA solicits applications for research projects that use innovative, methodologically-integrated approaches to understand how circuit activity gives rise to mental experience and behavior. The goal is to support projects that can realize a meaningful outcome within 5 years. Applications should address circuit function in the context of specific neural systems such as sensation, perception, attention, reasoning, intention, decision-making, emotion, navigation, communication or homeostasis. Projects should link theory and data analysis to experimental design and should produce predictive models as deliverables. Projects should aim to improve the understanding of circuits of the central nervous system by systematically controlling stimuli and/or behavior while actively recording and/or manipulating dynamic patterns of neural activity. Projects can use non-human and human species, and applications should explain how the selected species offers ideal conditions for revealing general principles about the circuit basis of a specific behavior.

Education
State governments
NM FY25 IIJA/IRA Bureau of Land Management New Mexico Cultural and Paleontological Resource Management
$150,000
U.S. Department of the Interior (Bureau of Land Management)
Federal

Application Deadline

Feb 26, 2025

Date Added

Dec 20, 2024

This funding opportunity supports projects that preserve cultural and paleontological resources on federal lands in New Mexico, targeting state, local, and tribal governments, educational institutions, and nonprofit organizations.

Natural Resources
State governments
American Schools and Hospitals Abroad Program Worldwide
$2,000,000
USAID (Agency for International Development)
Federal
Rolling

Application Deadline

Not specified

Date Added

Jan 19, 2023

ASHA's Fiscal Year 2023 draft Request for Applications (RFA) is posted.ASHA intends to post the FY 2023 official RFA by late June 2023 and give at least 30 days for Phase 1 app submission.Please keep an eye out for updates from PartnerwithASHA@usaid.gov for information on the FY 2023 RFA as well as future opportunities with ASHA and USAID. If you are not subscribed to the ASHA listserv, join by sending an email to PartnerwithASHA@usaid.gov with the subject "ASHA Listserv Membership Request," and your full name and email address in the body of the email.Please submit applications to ASHAapplications@usaid.gov. Submissions will not be accepted through the grants.gov portal.

Education
Nonprofits
Defense Sciences Office (DSO) Office-wide BAA
Contact for amount
U.S. Department of Defense (DARPA - Defense Sciences Office)
Federal

Application Deadline

Jun 2, 2026

Date Added

Jun 4, 2025

This grant provides funding for innovative research proposals that advance scientific and technological breakthroughs to enhance national security, targeting a wide range of applicants including private institutions, nonprofits, and small businesses.

Science and Technology
For profit organizations other than small businesses
Rehabilitation Research and Training Center (RRTC): National Research Center for Parents with Disabilities
$925,000
U.S. Department of Health and Human Services (Administration for Community Living)
Federal

Application Deadline

Not specified

Date Added

Sep 8, 2025

This funding opportunity provides resources to organizations conducting research and training to improve support and services for parents with disabilities, helping them navigate their parenting roles effectively.

Science and Technology
State governments
Transition to Independent Environmental Health Research (TIEHR) Career Award (K01 Independent Basic Experimental Studies with Humans Required)
$125,000
HHS-NIH11 (National Institutes of Health)
Federal

Application Deadline

May 7, 2024

Date Added

Mar 15, 2021

The Transition to Independent Environmental Health (TIEHR) Career Award is a 3-year bridge scholar development program for newly independent faculty who intend to pursue research careers in environmental health sciences. At the conclusion of the career development period the candidates are expected to demonstrate they can successfully compete for research funding in the environmental health sciences. All applications submitted to this Funding Opportunity Announcement must propose basic science experimental studies involving humans, otherwise referred to in NOT-OD-18-212 as prospective basic science studies involving human participants, that fall within the NIH definition of a clinical trial and also meet the definition of basic research.

Environment
Public and State controlled institutions of higher education
Climate Adaptation Science Center Grants
Contact for amount
U.S. Department of the Interior
Federal

Application Deadline

Not specified

Date Added

Oct 3, 2024

This funding opportunity supports organizations in the Northeast, South Central, and Pacific Islands regions to develop innovative climate adaptation strategies that address local environmental challenges.

Environment
State governments
Fair Housing Initiatives Program - Private Enforcement Initiative (PEI)
$425,000
Housing & Urban Development (Department of Housing and Urban Development)
Federal

Application Deadline

Aug 21, 2025

Date Added

Jul 30, 2025

This funding opportunity provides financial support to nonprofit organizations dedicated to enforcing fair housing laws through testing, investigation, and legal activities.

Housing
Nonprofits