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Grants for Nonprofits - Federal

Explore 5,314 grant opportunities

Techgate
$25,000,000
U.S. Department of State (Bureau of Cyberspace and Digital Policy)
Federal

Application Deadline

Aug 29, 2025

Date Added

Jul 23, 2025

This funding opportunity provides financial support to U.S.-based nonprofit organizations and for-profit businesses to help foreign governments adopt trusted digital technologies, enhancing cybersecurity and infrastructure resilience while countering potentially harmful foreign technology influences.

Science and Technology
For profit organizations other than small businesses
BJA FY25 Second Chance Act Community-based Reentry Incubator Initiative
$4,000,000
U.S. Department of Justice (Bureau of Justice Assistance)
Federal

Application Deadline

Mar 4, 2025

Date Added

Jan 13, 2025

This funding opportunity provides financial support to nonprofit organizations that help smaller community-based groups improve services for exonerees transitioning back into society after wrongful incarceration.

Law Justice and Legal Services
Nonprofits
Mentored Research Scientist Development Award (Parent K01 Independent Basic Experimental Studies with Humans Required)
$100,000
HHS-NIH11 (National Institutes of Health)
Federal

Application Deadline

May 7, 2024

Date Added

May 7, 2020

The purpose of the NIH Mentored Research Scientist Development Award (K01) is to provide support and protected time (three to five years) for an intensive, supervised career development experience in the biomedical, behavioral, or clinical sciences leading to research independence. Although all of the participating NIH Institutes and Centers (ICs) use this support mechanism to support career development experiences that lead to research independence, some ICs use the K01 award for individuals who propose to train in a new field or for individuals who have had a hiatus in their research career because of illness or pressing family circumstances. Other ICs offer separate K01 FOAs intended to increase research workforce diversity.

Education
State governments
ML/AI Tools to Advance Genomic Translational Research (MAGen) - Development Sites (UG3/UH3 Clinical Trials Not Allowed)
$1,600,000
U.S. Department of Health and Human Services - National Institutes of Health
Federal

Application Deadline

Jul 28, 2024

Date Added

May 11, 2024

NHGRI aims to setup a research Consortium, ML/AI Tools to Advance Genomic Translational Research (MAGen), to collaboratively explore the feasibility of developing Machine Learning (ML) and Artificial Intelligence (AI) tools that can enhance the accuracy and precision of predicting how individuals with pathogenic genetic variants manifest disease. The primary goal is to identify both genomic and non-genomic factors influencing disease development in individuals carrying pathogenic genetic variants. The ML/AI tools will leverage existing multimodal genomic and non-genomic data and will be cross validated in genomic translational research settings to ensure the accuracy and generalizability of the tools for translational purposes. In addition, the Consortium will explore the ethical, legal, and social implications (ELSI) of integrating ML/AI tools into genomic medicine through the establishment of an ELSI Framework for their development, and through implementation of ELSI research projects.

Health
State governments
Cooperative Agreement for In Vivo High-Resolution Imaging for Inner Ear Visualization (U01 Clinical Trial Required)
$500,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 5, 2025

Date Added

Nov 9, 2023

This funding opportunity supports innovative clinical trials aimed at developing advanced imaging technologies to visualize the inner ear's structures and functions in living patients with high precision.

Health
State governments
NIDA Program Project Grant Applications (P01 Clinical Trial Optional)
Contact for amount
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 25, 2025

Date Added

Jan 10, 2023

This funding opportunity supports collaborative research projects by multidisciplinary teams focused on addressing significant challenges related to substance use disorders and their health consequences.

Education
State governments
NIDA REI: Research on Neurocognitive Mechanisms Underlying the Impact of Structural Racism on the Substance Use Trajectory (R61/R33 Clinical Trial Optional)
$500,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 14, 2024

Date Added

Aug 9, 2022

This funding opportunity supports research that explores how structural racism affects brain function and substance use risk, aiming to develop effective prevention strategies for substance use disorders among racial and ethnic minority populations.

Education
State governments
Multi-Source, Multi-Domain Data Exploitation for Battlespace Awareness and Decision Support
$5,000,000
Department of Defense - Air Force Research Laboratory (AFRL)
Federal

Application Deadline

Not specified

Date Added

Mar 18, 2025

This grant provides funding for innovative research and development projects that enhance military decision-making and battlespace awareness through advanced data processing and analytics technologies.

Science and Technology
For profit organizations other than small businesses
IIJA/IRA Bureau of Land Management Alaska Plant Conservation and Restoration Management
$100,000
U.S. Department of the Interior (Bureau of Land Management)
Federal

Application Deadline

Mar 17, 2025

Date Added

Nov 26, 2024

This grant provides funding for state, local, and tribal governments, educational institutions, and nonprofit organizations to promote ecological restoration and biodiversity through the use of native plant materials in Alaska.

Natural Resources
State governments
Strengthening the Cyberinfrastructure Professionals Ecosystem (SCIPE)
Contact for amount
National Science Foundation
Federal

Application Deadline

Jan 15, 2026

Date Added

May 28, 2025

This grant provides funding to enhance the skills and integration of Cyberinfrastructure Professionals in research, supporting initiatives that improve access to advanced computing resources and training in science and engineering.

Science and Technology
Public and State controlled institutions of higher education
2025 VBOC Directed Announcement - Renewal
$585,000
Small Business Administration (Small Business Administration)
Federal

Application Deadline

Apr 11, 2025

Date Added

Apr 4, 2025

This funding opportunity provides financial support to nonprofit organizations that assist veterans in starting and growing their own businesses through training, counseling, and management assistance.

Business and Commerce
Nonprofits
Foreign Assistance Leveraged for Cybersecurity Operational Needs - FALCON
$10,000,000
U.S. Department of State - Bureau of Cyberspace and Digital Policy
Federal

Application Deadline

Aug 2, 2024

Date Added

Jun 11, 2024

CDPs Foreign Assistance Leveraged for Cybersecurity Operational Needs FALCON project is intended to establish and maintain a reservoir of primarily commercial cybersecurity and technology capabilities that CDP can draw upon in short order and in a wide variety of situations to support U.S. allies and partners to effectively prevent, respond to, mitigate, and recover from cybersecurity incidents. The objective of the project is to support partner governments, their subordinate agencies and critical infrastructure operators and partners in their efforts to identify, prevent, respond to, mitigate and recover from cybersecurity incidents.

Science and Technology
Nonprofits
Countering Crowdfunding for Terrorism Financing
$1,480,019
DOS-SCT (Bureau of Counterterrorism )
Federal

Application Deadline

May 17, 2024

Date Added

Mar 13, 2024

The Bureau of Counterterrorism (CT) of the U.S. Department of State announces an open competition for organizations to submit applications to improve selected countries capacities to counter the financing of terrorism conducted via crowdfunding, including through misuse of the non-profit organization (NPO) sector and use of virtual assets. The Bureau of Counterterrorism's mission is to promote U.S. national security by taking a leading role in developing coordinated strategies and approaches to defeat terrorism abroad and securing the counterterrorism cooperation of international partners.

Law Justice and Legal Services
Nonprofits
Short-Term Research Education Program to Enhance Diversity in Health-Related Research (R25 Clinical Trial Not Allowed)
$175,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Feb 21, 2025

Date Added

Feb 12, 2025

This funding opportunity provides financial support for educational programs that create research experiences in health-related fields for undergraduate and health professional students from diverse and underrepresented backgrounds.

Health
State governments
BRAIN Initiative: Development and Validation of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in the Brain (R01 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 14, 2024

Date Added

Jun 16, 2023

This grant provides funding for researchers to develop and validate innovative tools that improve the analysis of brain circuits and cellular interactions, with a focus on targeting specific cell types and circuits across various species.

Education
State governments
Quantum Computing for Computational Chemistry (QC3)
$10,000,000
U.S. Department of Energy (Advanced Research Projects Agency Energy )
Federal

Application Deadline

Nov 21, 2024

Date Added

Oct 25, 2024

This funding opportunity supports U.S.-based institutions in developing innovative quantum computing solutions to significantly improve computational chemistry and materials science for energy applications.

Energy
Public and State controlled institutions of higher education
Community Level Innovations for Improving Health Outcomes
$600,000
HHS-OPHS (Office of the Assistant Secretary for Health)
Federal

Application Deadline

May 15, 2024

Date Added

Mar 6, 2024

The Office of Minority Health announces the anticipated availability of funds for Fiscal Year (FY) 2024 under the authority of 42 U.S.C. 300u-6 (Section 1707 of the Public Health Service Act).This notice solicits applications for projects to demonstrate that community level innovations that reduce barriers related to social determinants of health (SDOH) can increase use of preventive health services and make progress toward Leading Health Indicator (LHI) targets. LHIs are a subset of high priority Healthy People 2030 (HP2030) objectives selected to drive action toward improving health and well-being. SDOH are described in HP2030 as conditions in the environments where people are born, live, learn, work, play, worship, and age that affect a wide range of health, functioning, and quality-of-life outcomes and risks.We anticipate the availability of $8,000,000 for up to 14 awards, ranging from $475,000 to $600,000 annually, for a period of performance of up to 48 months. Recipients will be required to report on progress and milestones as part of an annual noncompeting continuation application. Costs of medical services are unallowable under this funding opportunity. Early in the fourth budget period, we anticipate offering a competing continuation opportunity for an additional 12-month budget period (i.e., a fifth budget period) to support selected successful projects in their transition to sustainability. Funding available for the additional budget period is not guaranteed nor expected to be at the same level of previous budget periods. The Office of the Assistant Secretary for Health (OASH) Grants and Acquisitions Management Division (GAM) will administratively support this competition. GAM encourages all applicants to review all program requirements, eligibility information, application format and submission information, evaluation criteria, and other information in this notice to ensure that applications comply with all requirements and instructions.

Health
State governments
Research Opportunities for New and "At-Risk" Investigators to Promote Workforce Diversity (R01 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Feb 4, 2025

Date Added

Nov 22, 2024

This funding opportunity supports independent research projects by early-career and at-risk scientists from diverse backgrounds to enhance workforce diversity and address health disparities in various biomedical fields.

Health
State governments
Feasibility of Novel Diagnostics for TB in Endemic Countries (FEND for TB) (R01 Clinical Trial Not Allowed)
$3,500,000
HHS-NIH11 (National Institutes of Health)
Federal

Application Deadline

Jun 28, 2024

Date Added

Mar 28, 2024

The purpose of this notice of funding opportunity (NOFO) is to support the evaluation of early-stage diagnostics and novel diagnostic strategies for Tuberculosis (TB) in the context of existing clinical algorithms in TB endemic countries. Evaluation studies should: 1) perform proof-of principle studies of novel diagnostic tests and strategies for TB, including among people living with HIV (PLWH) and 2) provide feedback to diagnostic developers and policy makers on the performance of the technologies and most effective strategies for use of the diagnostic technologies in an endemic setting.

Health
State governments
FY25 IIJA/IRA Bureau of Land Management Oregon/Washington (ORWA) Rangeland Resource Management
$500,000
U.S. Department of the Interior (Bureau of Land Management)
Federal

Application Deadline

Feb 18, 2025

Date Added

Nov 15, 2024

This funding opportunity provides financial support for projects that conserve and restore rangelands in Oregon and Washington, focusing on climate resilience and environmental health, and is open to state, local, and tribal governments, educational institutions, and nonprofit organizations.

Natural Resources
State governments