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Grants for Nonprofits - Federal

Explore 6,593 grant opportunities

Project Grants
$300,000
State Justice Institute (SJI)
Federal
Rolling

Application Deadline

Not specified

Date Added

Aug 7, 2025

This funding opportunity supports state and local courts, as well as national nonprofit organizations, in implementing innovative projects that enhance judicial administration and improve the quality of justice in the U.S.

Law Justice and Legal Services
State governments
National Science Foundation Translation to Practice
$2,000,000
National Science Foundation
Federal

Application Deadline

Sep 16, 2026

Date Added

Jul 10, 2025

This program provides funding to U.S. higher education institutions and nonprofit research organizations to help translate scientific discoveries into practical applications that address real-world challenges through collaboration with industry and government partners.

Science and Technology
Public and State controlled institutions of higher education
Multilateral Partnerships Leveraging Excellence
$2,500,000
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Sep 16, 2024

This funding initiative supports U.S.-based research teams in forming international partnerships with at least two other countries to tackle urgent global challenges through innovative scientific collaboration.

Science and Technology
Public and State controlled institutions of higher education
NSF STEM K-12
$750,000
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Aug 23, 2025

This funding opportunity supports a wide range of projects aimed at improving STEM education and learning outcomes in schools and informal settings across the United States, targeting institutions, organizations, and individuals involved in education and research.

Education
Public and State controlled institutions of higher education
Successor-in-Interest (Type 6 Parent Clinical Trial Optional)
Contact for amount
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Jul 17, 2027

Date Added

Jul 15, 2024

This funding opportunity supports U.S. and eligible foreign institutions in conducting research to measure the masses of exoplanets, enhancing our understanding of their properties and formation.

Education
State governments
Reissue of RFA-FD-22-001 - Efficient and Innovative Natural History Studies Addressing Unmet Needs in Rare Diseases (R01 Clinical Trials Optional)
$600,000
U.S. Department of Health & Human Services (Food and Drug Administration)
Federal

Application Deadline

Feb 8, 2028

Date Added

Jul 12, 2025

This funding opportunity supports research projects that investigate the natural history of rare diseases, aiming to improve medical product development and patient outcomes through collaborative studies and innovative methodologies.

Health
Public and State controlled institutions of higher education
The NIDDK Disorders of Gastrointestinal Interoception Consortium Clinical Centers (DGIC)
$3,000,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 1, 2026

Date Added

Sep 19, 2025

This funding opportunity supports clinical research centers focused on understanding and improving treatments for various gastrointestinal disorders by exploring how the body senses and interprets internal signals, benefiting both adults and children.

Health
Public and State controlled institutions of higher education
DEVCOM Analysis Center Broad Agency Announcement For Applied Research
Contact for amount
U.S. Department of Defense (Dept of the Army -- Materiel Command)
Federal
Rolling

Application Deadline

Jan 4, 2028

Date Added

Jan 5, 2023

This funding opportunity is designed to support a wide range of research proposals from universities, nonprofits, businesses, and government entities that aim to advance the U.S. Army's technological capabilities and operational effectiveness.

Science and Technology
Nonprofits
NHLBI Program Project Applications (P01 Clinical Trials Optional)
Contact for amount
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 25, 2026

Date Added

Nov 20, 2023

This funding opportunity supports collaborative research projects focused on heart, lung, and blood diseases, encouraging innovative approaches and participation from emerging scientists.

Health
State governments
DoW Amyotrophic Lateral Sclerosis Research Program, Therapeutic Idea Award
$840,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Sep 30, 2026

Date Added

May 5, 2026

This funding opportunity supports innovative research projects aimed at developing new therapies for amyotrophic lateral sclerosis (ALS), particularly those that include biomarker development to measure treatment effects, and is open to a wide range of researchers and organizations.

Health
Nonprofits
DoW Peer Reviewed Cancer, Clinical Trial Award
$4,500,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Oct 5, 2026

Date Added

May 7, 2026

This funding opportunity supports clinical trials aimed at improving cancer treatment and management for various types of cancer, specifically targeting military populations and involving significant patient advocate participation.

Health
Nonprofits
Data Coordinating Center for Multi-Site Investigator-Initiated Clinical Trials (Collaborative U24 Clinical Trial Required)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 2, 2028

Date Added

Aug 5, 2025

This grant provides funding to establish a Data Coordinating Center that will support multi-site clinical trials focused on improving health outcomes related to cardiovascular, lung, blood, and sleep disorders.

Health
State governments
NCI Community Oncology Research Program (NCORP) Research Bases (UG1 Clinical Trial Required)
$74,500,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 18, 2026

Date Added

May 29, 2025

This funding opportunity provides financial support to U.S.-based organizations with established cancer research capabilities to develop and conduct multi-institutional clinical trials focused on cancer prevention, control, and care delivery in community settings.

Health
Public and State controlled institutions of higher education
Novel Experiential Technologies Assisting Individual Learning (NExT AI) Hubs
$1,600,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 2, 2026

Date Added

Jul 9, 2025

This funding opportunity supports research centers that will investigate how innovative artificial intelligence technologies can improve learning outcomes for children with specific learning disabilities affecting literacy and numeracy skills.

Science and Technology
State governments
DoW Orthopaedic, Clinical Research Award
$3,200,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Nov 18, 2026

Date Added

May 22, 2026

This funding opportunity supports clinical research and trials focused on improving recovery and treatment for military personnel with orthopaedic injuries, while also benefiting the general public.

Science and Technology
Nonprofits
Computational Mathematics
$200,000,000
National Science Foundation
Federal

Application Deadline

Dec 1, 2026

Date Added

Dec 10, 2024

This funding opportunity supports research in mathematical sciences, particularly innovative computational methods and algorithms, aimed at advancing scientific knowledge and competitiveness in the U.S.

Science and Technology
Public and State controlled institutions of higher education
Rfa-Dp-18-000
Contact for amount
U.S. Department of Health and Human Services (Centers for Disease Control and Prevention - ERA)
Federal

Application Deadline

Sep 30, 2030

Date Added

Nov 26, 2025

This funding opportunity provides support for states, universities, and nonprofit organizations to enhance existing public health and injury prevention programs through administrative supplements to their current CDC grants.

Health
State governments
DoW Reconstructive Transplant, Concept Award
$200,000
U.S. Department of Defense (Dept. of the Army -- USAMRAA)
Federal

Application Deadline

Nov 4, 2026

Date Added

Jun 1, 2026

This funding opportunity supports innovative research projects aimed at improving reconstructive transplantation techniques and access for injured Service Members, Veterans, and the general public.

Science and Technology
Nonprofits
MENA Freedom 250 NFL Flag Football Launch and Championship
$150,000
U.S. Department of State (U.S. Mission to Saudi Arabia)
Federal

Application Deadline

Sep 14, 2026

Date Added

Sep 1, 2026

This grant provides funding to nonprofit organizations and educational institutions to develop flag football programs and host a regional championship in the Middle East and North Africa, promoting American culture and youth engagement through sports.

Recreation
Nonprofits
Engineering (ENG): Civil, Mechanical and Manufacturing Innovation (CMMI)
$100,000,000
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Aug 18, 2026

This grant provides funding for researchers and innovators in civil, mechanical, and manufacturing fields to explore foundational advancements that can lead to safer, more efficient, and resilient systems and materials.

Science and Technology
Public and State controlled institutions of higher education