Grants for Nonprofits - Federal

The U.S. Department of Justice (DOJ), Office of Justice Programs (OJP), Bureau of Justice Statistics (BJS) is seeking applications for funding. OJP is committed to advancing work that promotes civil rights and equity, increases access to justice, supports crime victims and individuals impacted by the justice system, strengthens community safety, protects the public from crime and evolving threats, and builds trust between law enforcement and the community. With this solicitation, BJS seeks to collect data on persons who died in the custody of federal law enforcement (LE) agencies in FY 24, FY 25, and FY 26, building on BJSs existing efforts. The data collection will include a web-based interface to allow federal LE agencies to identify all deaths that are arrest-related or that occur in detention or incarceration facilities. This program furthers the DOJs mission to uphold the rule of law, to keep our country safe, and to protect civil rights.

This funding opportunity is designed to establish a central hub that will support collaborative genetic research on Alzheimer’s disease and related dementias, focusing on diverse populations and innovative data-sharing practices.

The purpose of this Funding Opportunity Announcement (FOA) is to support innovative population-based research that can contribute to identifying and characterizing pathways and mechanisms through which work or occupation influences health outcomes and health status among populations with health and/or health care disparities, and how work functions as a social determinant of health.The main objective of this initiative is to determine the extent and mechanisms by which work as a SDOH both contributes to, and helps ameliorate, health and health care disparities. A recent workshop on September 28-29, 2020 organized by NIMHD (https://www.nimhd.nih.gov/news-events/conferences-events/hd-workshop.html) highlighted key ideas for furthering research on work as a SDOH that include conceptualizing work as a social class marker, as a source of exposures and risk factors, and as a source of beneficial social and economic resources such as income and wealth, neighborhood conditions, health care access, education, and social networks. Some key questions include: What are the specific and modifiable mechanisms by which work explains health disparities? To what extent does work as a social class marker, source of exposures and risk factors and/or source of beneficial social and economic resources explain health disparities? Which health disparities does work as a SDOH explain? Of particular interest are projects designed to examine pathways and mechanisms using conceptual model(s) grounded in minority health and health disparities theories that recognize that health disparities arise by multiple and overlapping contributing factors acting at multiple levels of influence (See the NIMHD Research Framework, https://www.nimhd.nih.gov/about/overview/research-framework.html). Studies must examine NIH-designated U.S. health disparity populations, e.g. racial and ethnic minority populations, sexual and gender minority groups, underserved rural populations, and socioeconomically disadvantaged populations of any race or ethnicity (https://www.nimhd.nih.gov/about/overview/). Studies involving primary data collection with human participants are strongly encouraged to incorporate SDOH measures from the Core and Specialty collections that are available in the Social Determinants of Health Collection of the PhenX Toolkit (www.phenxtoolkit.org). Of interest are intersectional approaches that consider different social identities and the embeddedness of individuals within families, households, and communities. Life course approaches that consider the role of work in shaping cumulative processes and critical transitions including periods of unemployment, under-employment, and unpaid and informal work arrangements, are also encouraged. Also, of interest is considering the role of work at the household level with influences on the health of partners and extended families, and the intergenerational transmission to children and their health. In addition, exploring the role of inequity-generating mechanisms that constrain choices around work and health such as racism and discrimination by sex, age, marital status, immigration status, social class, and other power structures is also encouraged. Additionally, of interest are projects that explore whether work can explain the health or health care disparities seen within diseases or conditions (e.g., COVID-19, opioid use disorder, mental/behavioral health, diabetes, cancer, heart disease, asthma, and maternal and infant health ) as well as disparities in co-morbidities and general indicators of health such as greater global burden of disease, quality of life, and daily functioning. Projects that utilize a syndemics lens (i.e., multiple disease states that are interlinked because of social, environmental, and structural conditions), to examine the role of work in disparities in co-occurring health conditions, are encouraged. Also, of interest are projects that explore how work contributes to health care disparities including but not limited to disparities in access to preventive, specialty, and emergency care, in health insurance coverage, and in quality of health care. Moreover, given the reciprocal relationship between work and health, of interest are projects that examine how health impacts access to different work opportunities, working conditions, and work benefits, and how that varies by different social identities. Projects may involve primary data collection and/or secondary analysis of existing datasets. Projects may utilize observational studies, natural experiments, quasi-experiments, simulation modeling, as well as use of large-scale longitudinal data sets, data mining techniques, registries, surveillance data, and linking to administrative data sets such as the Occupational Information Network (O*NET). Quantitative and mixed methods approaches are encouraged. Investigators are encouraged as appropriate for the research questions posed, to forge research collaborations with community partners and stakeholders in the conceptualization, planning and implementation of the research to generate better-informed hypotheses and enhance the translation of the research results into practice.

The grant titled "Phased Multi-Site Clinical Trial: Testing Prevention of Cardiovascular Disease in Young Adults With High Lifetime Risk Using Surrogate Outcomes - Clinical Coordinating Center" aims to fund a clinical trial that will identify and test interventions to slow or prevent the development of heart disease in young adults who are at low immediate but high lifetime risk, comparing the effectiveness of current guidelines, LDL-lowering therapy, and potentially other methods.

This funding opportunity supports researchers conducting multi-site clinical trials to evaluate complementary and integrative health approaches that combine physical and psychological therapies, aiming to gather essential data for future larger-scale studies.

Each funding opportunity description is a synopsis of information in the Federal Register application notice. For specific information about eligibility, please see the official application notice. The official version of this document is the document published in the Federal Register. Free Internet access to the official edition of the Federal Register and the Code of Federal Regulations is available on GPO Access at: http://www.access.gpo.gov/nara/index.html. Please review the official application notice for pre-application and application requirements, application submission information, performance measures, priorities and program contact information. For the addresses for obtaining and submitting an application, please refer to our Revised Common Instructions for Applicants to Department of Education Discretionary Grant Programs, published in the Federal Register on December 7, 2022. Purpose of Program: The EIR program, established under section 4611 of the Elementary and Secondary Education Act, as amended (ESEA), provides funding to create, develop, implement, replicate, or take to scale entrepreneurial, evidence-based (as defined in this notice), field-initiated innovations to improve student achievement and attainment for high-need students and to rigorously evaluate such innovations. The EIR program is designed to generate and validate solutions to persistent education challenges and to support the expansion of those solutions to serve substantially more students. The central design element of the EIR program is its multitier structure that links the amount of funding an applicant may receive to the quality of the evidence supporting the efficacy of the proposed project, with the expectation that projects that build this evidence will advance through EIRs grant tiers: Early-phase, Mid-phase, and Expansion. Early-phase, Mid-phase, and Expansion grants differ in terms of the level of prior evidence of effectiveness required for consideration for funding, the expectations regarding the kind of evidence and information funded projects should produce, the scale of funded projects, and, consequently, the amount of funding available to support each type of project. Early-phase grants must demonstrate a rationale (as defined in this notice). Early-phase grants provide funding for the development, implementation, and feasibility testing of a program that prior research suggests has promise, for the purpose of determining whether the program can successfully improve student achievement and attainment for high-need students. Early-phase grants are not intended to simply expand established practices or address needs unique to one particular context. Rather, the goal is to determine whether and in what ways relatively new practices can improve student achievement and attainment for high-need students. This notice invites applications for Early-phase grants only. The notices inviting applications for Mid-phase grants and Expansion grants are published elsewhere in this issue of the Federal Register. Assistance Listing Number (ALN) 84.411C.

This funding opportunity provides financial support for innovative research projects aimed at advancing the understanding and treatment of Alzheimer's disease and related dementias, inviting applications from a wide range of institutions and researchers.

Synthesis Centers are a mechanism used by NSF's Directorate for Biological Science (BIO) to bring together communities that leverage existing data to catalyze discoveries through synthesis, analysis, and integrative training. Research supported by the Division of Integrative Organismal Systems (IOS) in BIO focuses on organisms as integrated units of biological organization, i.e., why they are structured as they are and function as they do. IOS seeks to establish a new Synthesis Center to advance our ability to explain and predict organismal resiliency and plasticity in response to complex and dynamic environmental circumstances encountered over a lifespan through the synthesis of varied data sets and types that bridge multiple scales and levels. The Synthesis Center will enable innovative synthesis and analysis of available biological and related data by providing the vision, infrastructure, and expertise to advance new avenues of inquiry in organismal biology focused on organismal resilience and plasticity. To accomplish this vision, the Synthesis Center will adopt approaches that are based on open science, team science, and data-intensive methods that enable data synthesis, sharing and inclusive collaborations among researchers across multiple levels of biological inquiry that may include genomic, physiological, structural, developmental, behavioral, neural, immunological, and microbiological analyses across some or all the IOS subdisciplines. In addition to supporting data and knowledge synthesis, the Synthesis Center should train new generations of researchers in solving challenging research problems through data-intensive, open, cross-disciplinary, and collaborative science. The Synthesis Center is also expected to serve as an example in effectively engaging diverse scientists from different types of institutions and across multiple disciplines. These types of data syntheses are expected to provide the basis for fundamental scientific discoveries and/or potentially translational, use-inspired research. In doing so, the Synthesis Center will have a profound impact on the progress of science and society.

A. PROGRAM DESCRIPTION Executive Summary: U.S. Embassy Dushanbes Public Diplomacy Section (PDS) announces an open competition to implement the Academy for Women Entrepreneurs (AWE) in Tajikistan, a program that seeks to elevate the economic livelihood of 25 women in Panjakent District. The Academy of Women Entrepreneurs (AWE) is a global program that was established by the U.S. State Department's Bureau of Educational and Cultural Affairs in 2019 to provide women with the knowledge, networks, and access to launch or scale successful businesses. By promoting womens economic opportunities and ensuring that women have the capabilities and resources needed to participate in the economy, the AWE program directly supports the U.S. National Strategy on Gender Equity and Equality. Background: Due to the high rate of male labor migration and unemployment, more Tajik women are considering how to financially support their households. However, womens entrepreneurial activities are highly dependent on the effectiveness of the business environment in the country. Successful small business development creates new employment opportunities in Tajikistan and helps women support themselves and their families. Small businesses are fast becoming the main source of income for women in Tajikistan. Panjakent, a former trading city on the ancient Silk Road, is located in a strategic geographic area bordering Uzbekistan. After a 25-year hiatus, Tajikistan and Uzbekistan have restrengthened bilateral ties, and both countries are working to expand trade and economic cooperation with each other. In this manner, they have established free economic zones where businesspeople can put their ventures to work. The city of Panjakent and its surroundings is home to unique natural beauty, newly recognized UNESCO cultural heritage sites, and agricultural projects - all of which makes it a strategic location to empower women to advance economic and human development. The skills that women will learn through AWE will not only be valuable to establish stronger economic independence for themselves but also to contribute to more cross-border trade with neighboring Uzbekistan. Project Audience(s): The primary audience is approximately 25 Tajik women in Panjakent District who have some entrepreneurial skills, either with the capacity to scale-up current ventures in hospitality management, eco-tourism, and trade, or with experience working at local markets, such as in the areas of agricultural products, handicrafts, artisan products, or in service industries such as beauty parlors and sewing. Recruitment Criteria: a) Women aged 18 to 45. b) Holding high school and/or university degrees. c) Approximately 1-2 years business experience. d) Motivation to engage in long-term business or entrepreneurial activity. e) Must reside in the district of Panjakent or nearby villages. f) Womens leadership experience. g) Community service experience. h) Some English proficiency preferred, but not a requirement. In coordination with PDS Dushanbe, the implementer will organize informational meetings to spread the word about the project, its goals, objectives, and vision, and identify current or aspiring entrepreneurs in Panjakent District. This could include information sessions at American Space Panjakent and other relevant NGO offices and entities, but also outreach with flyers provided to target women working in local markets in the specified fields. Project Goal: To elevate the economic livelihood of current or aspiring women entrepreneurs in hospitality management, eco-tourism, trade, and handicrafts in Panjakent to support the tourism infrastructure of Panjakent District. Project Objectives: Objective 1: Improve women entrepreneurs confidence and motivation in pursuing and growing their businesses. Objective 2: Increase the ability of women from the Panjakent region to create and grow their businesses in hospitality management, eco-tourism, and trade through targeted training and mentorship activities. Training topics may include but are not limited to: U.S. small business best practices, business plan development, marketing, accounting, financial management, investment and financing, leadership, strategic planning, business registration, and more. Objective 3: Increase women entrepreneurs awareness and knowledge of tourism initiatives and business opportunities in Panjakent. Objective 4: Increase women entrepreneurs abilities to apply for funding opportunities, including grants, loans, and investments, to fuel their business growth and attract potential investors. Project Activities: Select 25 women entrepreneurs for the AWE project in Panjakent. Provide women entrepreneurs with the knowledge, networks, and access to launch or scale successful businesses in Panjakent through online and in-person trainings. This could include a mentoring program or other form of connection with the business community. Use the online training platform DreamBuilder to teach participants the fundamentals of starting or growing a small business from a U.S. perspective, offering modules on marketing, pricing, and bookkeeping, and includes a built-in business plan generator. Organize sessions to increase entrepreneurs understanding of the tourism potential of the region; this could include a three-day business tour to the city of Samarkand in Uzbekistan, which holds high potential for cross-border tourism and trade. Organize and hold a final pitch event, inviting potential investors to provide feedback. B. FEDERAL AWARD INFORMATION Length of performance period: 12 months Number of awards anticipated: 1 Award amounts: awards may range from a minimum of $25,000 to a maximum of Total available funding: $39,504 Award Ceiling: $39,504 Award Floor: $25,000 Type of Funding: ECA Anticipated program start date: September 1, 2024 This notice is subject to availability of funding. Funding Instrument Type: Cooperative Agreement Cooperative agreements are different from grants in that Embassy staff are more actively involved in the grant implementation. The Department of State will be substantially involved in carrying out the following aspects of this cooperative agreement: 1) Selection of AWE personnel. 2) Selection of AWE participants. 3) Monitor AWE programming. 4) Connect recipient with the U.S. Alumni Network of Tajikistan (USANT) 5) Connect regional AWE alumni with the first cohort of 25 Tajik women entrepreneurs. 6) Publish a press release on project completion. 7) Produce a video on project accomplishments. Recipient Responsibilities: 1) Collaborate with PDS Dushanbe in selecting the participants for AWE programming. 2) Coordinate all logistics for the events including promotion, venue arrangements, set up and take down, monitoring and evaluation of the events. 3) Engage ECA exchange alumni in AWE programming. 4) Translate Dreambuilder Online Learning Platform from English into Tajik to conduct mentoring and facilitation in local languages (fundamentals of starting or growing a small business from a U.S. perspective, offering modules on marketing, pricing, and bookkeeping, and includes a built-in business plan generator.) 5) Strengthen communication, media, and outreach plans in collaboration with USANT. 6) Connect AWE alumni across the globe with dynamic U.S. experts who can engage both virtually and in person on entrepreneurship and innovation-related topics.t 7) Submit 2024-2025 AWE alumni data to PDS Dushanbe. Program Performance Period: Proposed programs should be completed in 12 months or less. The Department of State will entertain applications for continuation grants funded under these awards beyond the initial budget period on a non-competitive basis subject to availability of funds, satisfactory progress of the program, and a determination that continued funding would be in the best interest of the U.S. Department of State. Support for Diversity, Equity, Inclusion, and Accessibility (DEIA): All programs should consider strategies for expanding the pool of individuals/organizations/beneficiaries to afford opportunities for as diverse and inclusive population as is feasible to bring diverse perspectives based on religion, sex, disability, race, ethnicity, sexual orientation, gender identity, gender expression, sex characteristics, national origin, and age to implementation of the program. The Public Diplomacy Section reserves the right to award less or more than the funds described under circumstances deemed to be in the best interest of the U.S. government, pending the availability of funds and approval of the designated Grants Officer. C. ELIGIBILTY INFORMATION 1. Eligible Applicants The following not-for-profit organizations are eligible to apply: Not-for-profit organizations Civil society/non-governmental organizations Public and private educational institutions Applicants are only allowed to submit one proposal per organization. If more than one proposal is submitted from an organization, all proposals from that institution will be considered ineligible for funding. 2. Cost Sharing or Matching Cost sharing or matching is not required for this funding opportunity, but is encouraged, as well as potential public private partnerships.

Microbes and communities of microbes have remarkable genetic, physiological and biochemical diversity, allowing them to flourish in environments all over the planet and in a variety of substrates and hosts. Given their relative importance to ecosystems around the world, to the economy and to health, researchers have studied microbial systems extensively and have a better understanding of their capabilities and impacts on hosts and the environment. In recent years, researchers have increasingly turned to microbes and their diverse capabilities for bioremediation and applications in biotechnology, agriculture, and medicine. Because of advances in molecular biology, synthetic biology and bioengineering, researchers now have the ability to assemble synthetic microbial communities that have novel compositions, genetics and phenotypes and to use these communities to address both fundamental biological questions and a range of societal problems. The goal of this solicitation is to support research that addresses one or more of the three themes: 1) define the underlying mechanisms or rules that drive the formation, maintenance or evolution of synthetic microbial communities, 2) use synthetic microbial communities to address fundamental biological questions, including questions in molecular biology, cellular/organismal biology, ecology and evolution and/or 3) build synthetic communities with biotechnology, bioeconomy or environmental engineering applications, including but not limited to the production of novel biorenewable chemicals, biodegradation of recalcitrant or forever chemicals, enabling a circular bioeconomy, fostering sustainable agriculture and mitigating the impacts of climate change. For theme 3, the emphasis should be on designing communities with novel capabilities and understanding the underlying mechanisms that lead to these novel capabilities. Proposals must address one or more of the three themes noted above. Highest funding priority is given to proposals that have outstanding intellectual merit and broader impacts, while proposals with weaknesses in either category (or those that are perceived as likely to have an incremental impact) will not be competitive. The most competitive broader impacts include assessment plans. Well-conceived broader impacts activities take time and resources; thus, proposers are encouraged to include appropriate costs for broader impacts in the budget. To better understand the societal benefits and risks, as well as the potential for misuse or unintended damage to natural biological systems, synthetic microbial communities proposals should include a careful consideration of the social, ethical, and biosafety/security dimensions of the research. Investigators may choose to address these issues either as part of intellectual merit or broader impacts. Reproducibility in research leads to data that is amenable to more powerful analysis and the potential for reuse of data and greater generation of knowledge. Reproducibility in biological research that is prone to context dependent biological variation presents a unique challenge for the synthetic microbial communities researchers. Investigators must follow or advance best practices in sample collection and preparation, experimental design, data analysis, model generation, and/or validation of mathematical and computational methods to produce scientifically defensible results.

Walla Walla DistrictThis announcement represents an opportunity to enter into a cooperative agreement with an organization for outdoor education and training while accomplishing maintenance on public lands consisting of park maintenance, vegetation management, prescribed burns, landscaping, and similar services. The U.S. Army Corps of Engineers (USACE) is seeking organizations that offer challenging education and job-training experience that helps young adults develop the skills they need to lead full and productive lives and offer opportunity for aid with formal post high school education. Statutory Authority: Water Resources Development Act of 2000, Title 33, Part 2339, Section 213(a), Public Law 106-106-541, 114 Stat. 2593 (codified as amended at 33 U.S.C. 2339).

This funding opportunity supports researchers investigating the harmful effects of high-risk chemical exposures on lung and eye health, particularly in relation to public health emergencies.

This funding opportunity supports predoctoral students in dual-degree programs at institutions without NIH-funded training programs, helping them pursue research and clinical training to become future physician-scientists.

This funding opportunity is designed to support local governments, nonprofits, and educational institutions in Nebraska in providing culturally and linguistically appropriate health outreach and support services for newly arrived refugees.

This funding opportunity announcement (FOA) focuses on sensitivity and tolerance mechanisms underlying the development of alcohol use disorder. The intent of this FOA is to: (1) develop hypotheses about cellular, molecular or network mechanisms that regulate sensitivity and tolerance to alcohol, and (2) develop quantitative models to predict the development of tolerance and the progression to alcohol use disorder. These objectives will be accomplished with a Phased Innovation (R21/R33) mechanism, clinical trial optional, in which secondary data analysis or pilot studies can occur during the R21 phase, and research testing the hypotheses can be expanded in the R33 phase. The transition to the R33 phase will be determined by NIAAA program staff after evaluation of the achievement of specific milestones set for the R21 phase.

This initiative will support national service centers for molecular structure determination by high resolution cryoelectron microscopy (cryoEM). The centers will provide access to state-of-the-art equipment, technical support, and training for the production and analysis of high-resolution data and offer equal-opportunity nationwide access to services through an open application process.

This funding opportunity provides financial support to various organizations for delivering essential services to victims of crime, including children, the elderly, and other affected individuals, across the United States.

This funding initiative provides financial support to African scientists and institutions, along with global partners, to advance the development of an effective HIV vaccine through collaborative research and clinical trials.

The Embassy of the United States of America in Paraguays Public Diplomacy (PD) section of the U.S. Department of State announces an open competition for organizations to submit applications to carry out a program to implement the Academy of Women Entrepreneurs (AWE) FY-2024 program in Paraguay. The AWE program is an initiative to support and empower women entrepreneurs around the world. Through a hybrid learning experience, Paraguayan women will have the opportunity to explore the fundamentals of business, such as preparing business plans and raising capital, with the goal of building a better future for themselves, their families, and their communities. The AWE program is supported with the DreamBuilder platform developed by Thunderbird University, an online course that reinforces entrepreneurship components. This year, the AWE Paraguay program seeks to reach all 17 departments of Paraguay, empowering 100 women through the DreamBuilder platform, and virtual meetings.

This funding opportunity supports researchers exploring the mechanisms and effects of trained immunity in the immune system, particularly its implications for infectious diseases and immune-related conditions.