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Grants for Nonprofits - Federal

Explore 6,598 grant opportunities

Bipartisan Infrastructure Law San Francisco Bay Water Quality Improvement Fund
$2,000,000
Environmental Protection Agency (Environmental Protection Agency)
Federal

Application Deadline

Apr 17, 2025

Date Added

Oct 28, 2024

This funding opportunity supports projects that improve information security and responsible technology practices in the Middle East and North Africa, targeting resilience in information ecosystems and enhancing security at critical entry points.

Environment
City or township governments
Artificial Intelligence and Technology Collaboratory Coordinating Center (U24 Clinical Trial Not Allowed)
$1,900,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Dec 9, 2025

Date Added

Jun 10, 2025

This funding opportunity supports U.S.-based organizations in developing a centralized hub to advance the use of artificial intelligence and technology in research related to aging and Alzheimer's Disease, fostering collaboration and stakeholder engagement across multiple projects.

Health
State governments
Strategic support for human resources for health for the Ministry of Health and Social Services (MOHSS) to sustain HIV epidemic control in Namibia under the U.S. President's Emergency Plan for AIDS Relief (PEPFAR)
$15,500,000
U.S. Department of Health and Human Services (Centers for Disease Control-GHC)
Federal

Application Deadline

Not specified

Date Added

Oct 6, 2025

This funding opportunity is designed to strengthen Namibia's healthcare workforce by providing support for the recruitment and management of health professionals to sustain efforts in controlling HIV and tuberculosis.

Health
State governments
Discovery and Development of Natural Products for Cancer Interception and Prevention (UG3/UH3 Clinical Trial Not Allowed)
$250,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 30, 2024

Date Added

Mar 23, 2023

The overall goal of this UG3/UH3 Exploratory/Developmental phased initiative is to support the discovery and development of novel natural products that are safe, nontoxic, and efficacious for cancer interception and prevention. 1. Purpose of UG3: Select clinically relevant targets and develop and validate assays for bioactivity as well as toxicity screening 2. Purpose of UH3 phase: Screening libraries, structure elucidation, full-scale characterization, efficacy testing, and development of the screened agents.

Education
State governments
Community Reentry Settings Initiative
$100,000
U.S. Department of Justice (National Institute of Corrections)
Federal

Application Deadline

May 4, 2026

Date Added

Mar 6, 2026

This funding opportunity is designed for organizations with extensive experience in criminal justice research to evaluate and improve the decision-making processes used by state Departments of Corrections for placing individuals in community reentry facilities.

Law Justice and Legal Services
Nonprofits
Delta Health Care Service Grant Program
$1,000,000
U.S. Department of Agriculture - Rural Business-Cooperative Service
Federal

Application Deadline

Aug 12, 2024

Date Added

Jun 13, 2024

The Rural Business-Cooperative Service announces the availability of $3,000,000 in competitive grant funds for the FY 2024 Delta Health Care Services Grant (DHCS) Program as authorized under Section 379G of the Consolidated Farm and Rural Development Act (7 U.S.C. 2008u), as amended by the Agricultural Act of 2018 (Pub. L. 115-334). The purpose of this program is to provide financial assistance to address the continued unmet health needs in the Delta Region, through cooperation among health care professionals, institutions of higher education, research institutions and economic development entities in the Delta Region.

Health
Public and State controlled institutions of higher education
Genetic Medicines And Individualized Manufacturing For Everyone (GIVE)
Contact for amount
U.S. Department of Health and Human Services
Federal

Application Deadline

Feb 27, 2026

Date Added

Sep 29, 2025

This program provides funding to a wide range of organizations, including nonprofits, universities, and businesses, to develop innovative solutions for producing personalized genetic medicines quickly and efficiently, improving patient access across the United States.

Health
For profit organizations other than small businesses
Ultra-Rare Gene-based Therapy (URGenT) Network Resource Access (X01, Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Dec 17, 2024

Date Added

Nov 9, 2021

This grant provides access to specialized resources and expertise for researchers developing gene-based therapies for extremely rare neurological disorders, helping them prepare for regulatory submissions and advance their therapeutic projects.

Health
State governments
Enhancing Global Health Security: Expanding Efforts and Strategies to Protect and Improve Public Health in Bangladesh
$20,000,000
U.S. Department of Health and Human Services (Centers for Disease Control-GHC)
Federal

Application Deadline

Jan 2, 2026

Date Added

Aug 22, 2025

This funding opportunity provides financial support to a wide range of organizations, including governments, educational institutions, and nonprofits, to strengthen public health systems and improve responses to infectious disease threats in Bangladesh.

Health
State governments
DoD Breast Cancer Clinical Research Extension Award
$8,400,000
U.S. Department of Defense (Dept. of the Army -- U.S.AMRAA)
Federal

Application Deadline

Jun 27, 2025

Date Added

May 27, 2025

This funding opportunity provides financial support for research projects that enhance data collection and analysis related to breast cancer, specifically targeting gaps in existing clinical studies and involving consumer advocates in the research process.

Science and Technology
Nonprofits
Lower Mississippi Delta Initiative Local Heritage Grant
$25,000
National Park Service
Federal

Application Deadline

May 31, 2024

Date Added

Apr 22, 2024

Deadline: May 31, 2024, at 4 p.m. CDT. Eligible Recipients: Not-for-profit organizations with preservation, conservation, cultural, historical, or archeological missions, including HBCUs, tribal nations, and government entities. Eligible Projects: Must be within the Delta Region, focusing on cultural heritage, public roads, regional music, museums, and more. Priority Criteria: Projects addressing immediate needs, new initiatives, completed within 18 months, and enhancing heritage tourism. Where: Projects within the Delta Region, not on federal property. When: Applications open April 15, 2024, and close May 31, 2024, at 4 p.m. CDT. Selected projects announced by September 2024. Webinar: Optional webinar on April 24 at 10 a.m. CDT. Register here. Contact: For project inquiries, email us. For technical support, contact grants@jnpa.com.

Community Development
Nonprofits
ROSES25: B.6 Heliophysics Technology and Instrument Development for Science
$2,350,000
National Aeronautics and Space Administration (NASA Headquarters)
Federal

Application Deadline

Apr 15, 2026

Date Added

Jan 13, 2026

This grant provides funding for universities and nonprofits to develop innovative technologies and instruments that advance research in solar and space physics, supporting NASA's goals for future space exploration.

Science and Technology
Public and State controlled institutions of higher education
American Spaces Administrative Funds Management 2026
$12,591
U.S. Department of State (U.S. Mission to Zambia)
Federal

Application Deadline

Jun 20, 2026

Date Added

May 29, 2026

This funding opportunity provides financial support for organizations in Zambia to manage the administrative logistics of American Spaces programs that promote cultural and educational engagement with the United States.

International Development
Nonprofits
ScaleUp Bolivia
$40,000
U.S. Department of State (U.S. Mission to Bolivia )
Federal

Application Deadline

Jul 15, 2026

Date Added

May 14, 2026

This funding opportunity supports non-profit organizations in helping over 100 informal Bolivian businesses transition into the formal economy through education, guidance, and partnerships, ultimately strengthening economic ties with the United States.

International Development
Nonprofits
Bureau of Ocean Energy Management Experienced Services Program (ESP)
$2,000,000
DOI-BOEM (Bureau of Ocean Energy Management)
Federal

Application Deadline

Jun 18, 2024

Date Added

Apr 27, 2024

To partner with a qualified nonprofit organization to supply BOEM with qualified candidates 55 years and older that will support the BOEM on projects related to renewable energy, decommissioning, well intervention, and others.The Experienced Services Program provides a cost-effective recruitment opportunity to obtain the services of non-federal, experienced workers aged 55 and older. Through agreements with eligible nonprofit organizations, the BOEM will be able to recruit and utilize the services of these workers on a project-specific basis to enhance its capacity to achieve its mission, goals, and objectives. The program will benefit the general public by supporting projects related to renewable energy, decommissioning, well intervention, and others. Skilled and experienced older Americans, including veterans, will have the opportunity to put their talents and experience to use on a part-time to full-time basis. Enrollment in the program will not impact the retirement benefits of retired federal employees.Partnering with a qualified nonprofit organization(s) is a cost-effective human capital tool designed to obtain the services of experience workers aged 55 and older on a temporary basis through a cooperative agreement to assist the BOEM in reaching its priorities and strategic goals. This allows the BOEM to focus on identifying its need(s) for specific expertise while not having to dedicate time and resources to recruit, hire and directly administer those resources.ESP participants will provide technical engineering, information technology, administrative, regulatory, and other support to BOEM to develop and execute projects that benefit the general public and provide support to BOEM employees. These projects will enable the BOEM to carry out its mission to manage development of U.S. Outer Continental Shelf energy and mineral resources in an environmentally and economically responsible way.

Employment Labor and Training
Nonprofits
The Gus Schumacher Nutrition Incentive Program - Nutrition Incentive Program
$500,000
U.S. Department of Agriculture (National Institute of Food and Agriculture)
Federal

Application Deadline

Apr 15, 2025

Date Added

Jan 15, 2025

This funding opportunity supports projects that encourage low-income individuals to buy more fruits and vegetables by providing financial incentives through authorized retailers.

Agriculture
Nonprofits
Consortium for Palliative Care Research Across the Lifespan (U54 Clinical Trial Optional)
$9,500,000
HHS-NIH11 (National Institutes of Health)
Federal

Application Deadline

Jul 2, 2024

Date Added

Feb 22, 2024

This Notice of Funding Opportunity (NOFO) invites applications for a U54 Specialized Center (henceforth: Consortium) to provide resources, expertise, and coordination to advance innovative, high-quality research on palliative care for those with serious illness across the lifespan. This research infrastructure will encompass Alzheimers disease and Alzheimers disease-related dementias (AD/ADRD), cancer, and other serious illnesses and populations relevant to the partnering Institutes, Centers, and Offices (ICOs). NIH currently funds many palliative care research projects across the ICOs, and there is a need for a structure to leverage synergies, coordinate efforts, develop the scientific workforce, and address remaining gaps in the field. The goals of this initiative include generating new scientific knowledge, in part through supporting pilot and exploratory studies; fostering development of early- and mid-career palliative care investigators; serving as a national platform to provide research resources and facilitate high-quality palliative care research; engaging healthcare systems and community-based organizations as research partners and settings for palliative care research; and disseminating research findings, best practices, data, and other impactful resources to the palliative care research and clinical communities. An important focus of the Consortiums work will be on facilitating research to understand and address disparities in access, quality, and use of palliative care services for health disparities populations or in underserved areas.

Education
State governments
U.S. Embassy Yangon Public Diplomacy Small Grants Competition
$99,999
U.S. Department of State (U.S. Mission to Myanmar)
Federal

Application Deadline

Apr 15, 2025

Date Added

Dec 23, 2024

This funding opportunity supports organizations and individuals in Myanmar to implement programs that strengthen cultural ties with the United States, focusing on education, entrepreneurship, media literacy, English language learning, and bilateral relations.

Education
Nonprofits
Puerto Rico Energy Resilience Fund: Resilient Communities Program
$185,000,000
U.S. Department of Energy (National Energy Technology Laboratory)
Federal

Application Deadline

Oct 22, 2024

Date Added

Aug 30, 2024

The "Puerto Rico Energy Resilience Fund: Resilient Communities Program" grant aims to use $1B in funding to enhance Puerto Rico's energy resilience and clean energy economy, particularly focusing on mitigating power outage impacts on low-income residents, ensuring energy reliability for healthcare services in disadvantaged communities, and supporting the growth of the clean energy workforce, through the installation of solar PV and battery storage in subsidized multi-family properties and community healthcare facilities.

Energy
Public housing authorities
Distance Learning and Telemedicine Grants
$1,000,000
U.S. Department of Agriculture (Rural Utilities Service)
Federal

Application Deadline

Mar 6, 2025

Date Added

Jan 7, 2025

This funding opportunity provides financial support to various organizations for improving healthcare and education services in rural areas through advanced telecommunications technology, with a focus on addressing substance use disorders and enhancing access to specialized resources.

Business and Commerce
State governments