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Grants for Nonprofits - Federal

Explore 5,329 grant opportunities

IDeA Networks of Biomedical Research Excellence (INBRE) (P20 Clinical Trial Optional)
$2,750,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

May 22, 2025

Date Added

Feb 10, 2023

This funding opportunity supports the development of biomedical research networks in underfunded states and territories, enhancing research capacity and collaboration among colleges and universities, particularly those serving undergraduate students.

Health
State governments
Examining the Impact of Artificial Intelligence (AI) on Healthcare Safety (R18)
Contact for amount
U.S. Department of Health and Human Services (Agency for Health Care Research and Quality)
Federal

Application Deadline

Sep 25, 2024

Date Added

Jul 18, 2024

The purpose of this NOFO is to invite grant applications that support healthcare safety by determining (1) whether and how certain breakthrough uses of Artificial Intelligence (AI) systems can affect patient safety; and (2) how AI systems can be safely implemented and used. AI has the potential to improve the safety, effectiveness, efficiency, accessibility, and affordability of healthcare. However, as with most technologies, this potential must be balanced by identifying and mitigating potential risks for patient harm and user burden.

Health
State governments
NINDS Faculty Development Award to Promote Diversity in Neuroscience Research (K01 Independent Clinical Trial Not Allowed)
$95,000
HHS-NIH11 (National Institutes of Health)
Federal

Application Deadline

May 7, 2024

Date Added

Apr 23, 2021

(Reissue of PAR-18-490) The purpose of the NINDS Faculty Development Award to Promote Diversity in Neuroscience Research (K01) is to diversify the pool of independent neuroscience research investigators by providing junior faculty with research cost support, protected research time and career stage appropriate professional development mentorship in neuroscience research. Individuals from backgrounds underrepresented in biomedical research are eligible for support under this award if they have doctoral research degrees (Ph.D. or equivalent) and are in the first 3 years of a faculty tenure track or equivalent position at the time of application. This Funding Opportunity Announcement (FOA) is designed specifically for applicants proposing research that does not involve leading an independent clinical trial, a clinical trial feasibility study, or an ancillary study to a clinical trial. Applicants to this FOA are permitted to propose research experience in a clinical trial led by a mentor or co-mentor.

Health
State governments
State-based Healthcare Extension Cooperatives to Accelerate Implementation of Actionable Knowledge into Practice (U19)
$6,250,000
U.S. Department of Health and Human Services (Agency for Health Care Research and Quality)
Federal

Application Deadline

Jan 7, 2025

Date Added

Sep 9, 2024

This grant provides funding to establish state-based cooperatives that will improve behavioral healthcare for medically underserved populations by implementing patient-centered improvements based on evidence from patient-centered outcomes research.

Health
State governments
Exploratory Clinical Neuroscience Research on Substance Use Disorders (R61/R33 Basic Experimental Studies with Humans (BESH) Required)
$500,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 9, 2025

Date Added

Apr 10, 2023

This funding opportunity provides financial support for innovative research aimed at understanding the brain mechanisms behind substance use disorders, targeting a wide range of applicants including universities, nonprofits, and private organizations.

Education
State governments
Research on Biopsychosocial Factors of Social Connectedness and Isolation on Health, Wellbeing, Illness, and Recovery (R01 Clinical Trial Required)
Contact for amount
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 7, 2024

Date Added

Oct 5, 2021

This funding opportunity announcement (FOA) invites research projects that seek to explain the underlying mechanisms, processes, and trajectories of social relationships and how these factors affect outcomes in human health, illness, recovery, and overall wellbeing. Types of projects submitted under this FOA include mechanistic studies that are classified as clinical trials. Mechanistic studies are defined as studies with the objective to understand the mechanism(s) of action of an intervention, a biological or behavioral process, or the pathophysiology of a disease/condition. See NOT-AT-20-001 and NOT-MH-19-006 for examples of clinical trials that are/are not considered mechanistic studies. Clinical trials that propose to influence a clinical outcome, test safety or feasibility of an intervention, demonstrate the clinical efficacy or effectiveness of an intervention, or analyze the effect size of an intervention on clinical outcomes are ineligible for this FOA. Types of studies that should submit under this FOA include clinical trials that assess biomedical or behavioral outcomes in humans for the purpose of understanding the fundamental aspects of phenomena without specific application towards processes or products in mind. Researchers proposing basic science experimental studies involving human participants should consider this FOAs companion for basic experimental studies with humans, TEMP-14931, Research on Health, Wellbeing, Illness, and Recovery (R01 Basic Experimental Studies with Humans Required). Applications proposing studies that include, but are not limited to, model animal research or observational studies involving humans should submit under the companion FOA, TEMP-14934, "Research on Biopsychosocial Factors of Social Connectedness and Isolation on Health, Wellbeing, Illness, and Recovery (R01 Clinical Trials Not Allowed).

Education
State governments
FY25 Bureau of Land Management Threatened and Endangered Species- Bureau wide
$1,000,000
U.S. Department of the Interior (Bureau of Land Management)
Federal

Application Deadline

Jul 23, 2025

Date Added

Jun 24, 2025

This funding opportunity provides financial support for conservation projects aimed at protecting and recovering endangered and threatened species across the United States, targeting eligible applicants such as state and local governments, educational institutions, tribal organizations, and nonprofits.

Natural Resources
State governments
USAID/Ghana Teaching and Learning Materials and Classroom Furniture (TLM+) Activity
$3,000,000
U.S. Agency for International Development (Ghana USAID-Accra)
Federal

Application Deadline

Oct 21, 2024

Date Added

Aug 21, 2024

The USAID/Ghana Teaching and Learning Materials and Classroom Furniture (TLM+) Activity grant is aimed at funding qualified local entities to improve educational resources and classroom furniture in Ghana, with the award going to the applicant who best meets the funding objectives as per the criteria outlined in the Notice of Funding Opportunity.

Education
Individuals
NSF Trailblazer Engineering Impact Award (Trailblazer)
$3,000,000
National Science Foundation
Federal

Application Deadline

Apr 15, 2025

Date Added

Aug 28, 2024

This grant provides funding for innovative researchers in engineering and science to explore new research directions that address national challenges and promote collaboration across disciplines.

Science and Technology
Nonprofits
2025 AWE Alumnae Regional Summit
$26,000
Department of State - Bureau of Western Hemisphere Affairs
Federal

Application Deadline

Jul 22, 2024

Date Added

Jul 18, 2024

The U.S. Embassy Nassaus Public Diplomacy (PD) section announces an open competition for organizations to submit applications to develop and organize a Regional Alumnae Summit for the Academy for Women Entrepreneurs (AWE) network throughout the Caribbean. The PD section invites proposals from non-profit organizations, civil society organizations, and U.S. government alumni organizations to design and organize a summit to connect small and medium businesses of AWE Alumnae from across the Caribbean during a 2-day Summit in Nassau, The Bahamas in Spring 2025. This Summit will also provide a forum for AWE Alumnae to expand their professional network, share best practices and gain broader market access. In consultation with the U.S. Embassy Public Diplomacy team, the awardee is expected to organize all logistics for the Summit to include, but not limited to several deliverables. Therefore, the proposal should clearly describe how each item below will be addressed: Structure and Overall plan for the event. The estimated Cost for the proposed Venue for the Summit. Equipment (Equipment cannot account for more than 10% of the total project cost.) Marketing plan Proposed 6 Conference Speakers and associated costs (this should include Bahamian, Caribbean and American Entrepreneurs as well as a Keynote Speaker.) Travel Costs for participants from Family Islands. A Business Expo opportunity for participants. Opportunities for participants to scale up their businesses (ex. export, product development and scaling.) Cost Share (not required but looked upon favorably) Public Private Partnerships Pre and Post Surveys for participants (ex. To garner input for topics for summit)

Women & Girl Services
Nonprofits
Fy25 Vietnam Wartime Accounting Initiative Cooperative Agreements
$550,000
U.S. Department of Defense (Washington Headquarters Services)
Federal

Application Deadline

Sep 28, 2025

Date Added

Aug 29, 2025

This grant provides funding to three specific organizations to support efforts in locating and recovering missing persons from the Vietnam War, thereby enhancing U.S.-Vietnam defense cooperation and addressing humanitarian concerns.

International Development
Public and State controlled institutions of higher education
Landscape Characterization and Monitoring in the Chesapeake Bay Watershed
$6,500,000
Environmental Protection Agency
Federal

Application Deadline

Jul 19, 2024

Date Added

May 20, 2024

Authorized by Clean Water Act (CWA) Section 117, 33 USC Section 1267, the Chesapeake Bay Program (CBP) is a unique regional, state, federal, and local partnership that has been directing and conducting the restoration and protection of the Chesapeake Bay. CBP is responsible for supporting the Chesapeake Bay Executive Council (Executive Council) through a number of actions, including the coordination of federal, state, and local efforts to restore and protect living resources and water quality of the Chesapeake Bay and its watershed. The Notice of Funding Opportunity is seeking insightful, expert, and cost-effective applications from eligible applicants to provide the CBPs non-federal partners with updated land use/land cover data, enhanced river corridor data, and landscape metrics and communication products associated with these data to facilitate their application to CBP's outcomes and the CBPs Phase 7 suite of modeling tools. For more information, please see the funding opportunity.

Environment
Nonprofits
DFC Support Program National Community Anti-Drug Coalition Institute (NCI)
$2,500,000
Office of National Drug Control Policy
Federal

Application Deadline

Sep 16, 2024

Date Added

Aug 13, 2024

Adolescence is a critical risk period for substance use initiation and adverse outcomes related to substance use, particularly as drug use has been found to escalate between ages 12 and 19. The goal of substance use prevention efforts is to prevent and/or delay the first use of substances. Research shows that early age of onset is an important predictor for the development of a substance use disorder later in life. Further, research shows that prevention interventions can have positive long-term effects in reducing substance use. Recognizing that preventing or delaying initiation of substance use can confer important health and social benefits, the purpose of the NCI is to serve as the training and technical assistance partner for DFC and non-DFC funded community coalitions across the country by enhancing the capacity of the prevention workforce and others in the prevention community to implement evidence-based interventions.

Health
Nonprofits
Combating Antibiotic-Resistant Bacteria Interdisciplinary Units (CARBIRUs) (P01 Clinical Trial Not Allowed)
$1,500,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Mar 26, 2025

Date Added

Nov 5, 2024

This grant provides funding for interdisciplinary research teams to develop innovative strategies for preventing and treating infections caused by antibiotic-resistant bacteria.

Health
State governments
Energy Improvements in Rural or Remote Areas Fiscal Year 2025 Release
$50,000,000
U.S. Department of Energy (Headquarters)
Federal

Application Deadline

Aug 28, 2025

Date Added

Jun 5, 2025

This funding opportunity provides financial support for clean energy projects in rural and remote areas, targeting communities with 10,000 residents or fewer to reduce energy costs and improve access to sustainable energy solutions.

Energy
Native American tribal organizations
Women's Business Center Application Readiness and Procurement Assistance
$150,000
U.S. Small Business Administration
Federal

Application Deadline

Aug 7, 2024

Date Added

Jun 11, 2024

The purpose of this Funding Opportunity Announcement (FOA) is to provide grant funding for organizations to establish Womens Business Centers (WBCs) to assist women entrepreneurs with application readiness for certification in the Women-Owned Small Business (WOSB) and Economically Disadvantaged Women-Owned Small Business (EDWOSB) Programs, procurement assistance, and entrepreneurial development.

Business and Commerce
Nonprofits
DRL FY23 Combatting Transnational Repression Globally
$2,640,000
DOS-DRL (Bureau of Democracy Human Rights and Labor)
Federal

Application Deadline

May 6, 2024

Date Added

Mar 5, 2024

The U.S. Department of State, Bureau of Democracy, Human Rights, and Labor (DRL) announces an open competition for organizations interested in submitting applications for a global project to 1) dissuade and deter governments from engaging in and/or facilitating transnational repression (TNR) activities and 2) mitigate the impact of TNR activities on individuals and communities. Competitive proposals will incorporate activities in at least three regions as defined by the State Department (Sub-Saharan Africa, East Asia and the Pacific, Europe and Eurasia, Middle East and North Africa, South and Central Asia, and Western Hemisphere).

International Development
Nonprofits
OJJDP FY25 National Mentoring Programs
$30,000,000
U.S. Department of Justice (Office of Juvenile Justice Delinquency Prevention )
Federal

Application Deadline

Nov 3, 2025

Date Added

Sep 19, 2025

This funding opportunity provides financial support to national organizations for delivering mentoring services to at-risk youth, particularly those involved in or affected by the juvenile justice system, across at least 38 states.

Youth
Nonprofits
DRL Strengthening the Rights of Workers in the Care Economy
$1,000,000
DOS-DRL (Bureau of Democracy Human Rights and Labor)
Federal

Application Deadline

Jul 15, 2024

Date Added

Jun 17, 2024

The U.S. Department of State, Bureau of Democracy, Human Rights, and Labor (DRL) announces an open competition for organizations interested in strengthening the rights of workers in the care economy in line with internationally recognized labor standards.

Workforce Development
Nonprofits
Leveling the Field for American Workers in U.S.-Mexico Trade
$10,000,000
U.S. Department of Labor (Bureau of International Labor Affairs)
Federal

Application Deadline

Sep 26, 2025

Date Added

Jul 22, 2025

This grant provides funding to organizations working to improve labor conditions in Mexico's key trade sectors, ensuring fair practices that benefit American workers and businesses.

Employment Labor and Training
Nonprofits